A collaborative paper is published with Professor Andrew Mugler's Group at the University of Pittsburgh regarding biophysical modeling of cellular sensing capability under chemical and fluidic cues in the Journal Physical Review Research. Quantifying cellular autonomy in multicue environmentsLouis González, Hogyeong Gwak, Bumsoo Han, and Andrew Mugler Abstract A cell routinely responds to one of many competing environmental cues.

Dr. Hye-ran Moon, who performed her PhD and Postdoc research training in our group, will starts her faculty appointment in the School of Integrative Engineering of Chung-Ang University, Seoul, South Korea. She established microphysiological systems of pancreatic cancer in the group, and implemented the MPS to drug discovery and cancer research. After graduation, she was a research scientist developing liver organoid at Korea Research Institute of Bioscience and Biotechnology. Congratulation and best wishes!

We bid a fond farewell to Sae Rome as she begins an exciting new chapter in her career. She starts Research Fellow at Mayo Clinic. During her time in the Group, Sae Rome made outstanding contributions in developing and implementing the microphysiological systems of pancreatic cancer for biology and drug discovery resaerch. Her scientific creativty and rigor, collaborative spirit, and friendship left a lasting impact on the group.

We bid a fond farewell to Sae Rome as she begins an exciting new chapter in her career. She starts Research Fellow at Mayo Clinic. During her time in the Group, Sae Rome made outstanding contributions in developing and implementing the microphysiological systems of pancreatic cancer for biology and drug discovery resaerch. Her scientific creativty and rigor, collaborative spirit, and friendship left a lasting impact on the group.

Our paper regarding targeting KRAS-mutant cancer cells using macropinocytosis is highlighted as a frontiepiece in the Journal Advanced Science. DNA Origami-Cyanine Nanocomplex for Precision Imaging of KRAS-Mutant Pancreatic Cancer Cells Hye-ran Moon, Yancheng Du, Sae Rome Choi, Seongmin Seo, Cih Cheng, Bennett D. Elzey, Jong Hyun Choi, and Bumsoo Han Abstract Selective delivery of imaging agents to pancreatic cancer cells (PCCs) within the highly desmoplastic tumors of pancreatic ductal adenocarcinoma (PDAC) represents a significant advancement.

An NNMT inhibitor reduces tumour burden and metastasis in multiple mouse cancer models and restores immune checkpoint blockade efficacy by decreasing cancer-associated-fibroblast-mediated recruitment of myeloid-derived suppressor cells and reinvigorating CD8+ T cell activation.

The brain’s response to injury includes the activation of intrinsic microglia and the influx of leukocytes, collectively constituting neuroinflammation, the “flame” of the brain. Although details diff...

Trauma leaves traces in the brain. A study of alterations in gene regulation in the brains of people with post-traumatic stress disorder offers insights into its biology.

Sex and gender research could lead to better, more equitable treatments — if it is allowed to continue without political interference.

The activity that consumes roughly one-third of our lives affects health in ways scientists are only beginning to fully understand.

Nature - The Haenyeo divers of the Korean island of Jeju have a genetic variant linked to pain tolerance, as do other people living on Jeju.

Last week, I was invited to share my group's research on pancreatic cancer at 2025 HopeTalks hosted by the UIUC Chapter of American Cancer Society. The enthusiasm and curiosity exhibited by the student attendees were truly inspiring.

An electroadhesive hydrogel interface achieves 30-day gastrointestinal retention for prolonged porcine mucosal theranostics.