Bruna Martins Garcia
@brunamgarcia.bsky.social
Postdoc 👩🔬 curious about everything unknown and passionate about #CancerMetabolism and #Mitochondria | Altea-Manzano lab, CABIMER - Seville, Spain | Schmidt Fellow 2024 | eLife ambassador | EACR ambassador
Reposted by Bruna Martins Garcia
RESEARCH | T Feng, Q Luo, J Yun et al (@mdanderson.bsky.social)
The combination of glucose and fructose in sugar-sweetened beverages promotes colorectal cancer metastasis via sorbitol dehydrogenase 🧪
www.nature.com/articles/s42...
The combination of glucose and fructose in sugar-sweetened beverages promotes colorectal cancer metastasis via sorbitol dehydrogenase 🧪
www.nature.com/articles/s42...
Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD - Nature Metabolism
Feng, Luo and colleagues show that the combination of glucose and fructose, as found in sugar-sweetened beverages, promotes colorectal cancer metastasis through a mechanism involving sorbitol dehydrog...
www.nature.com
November 8, 2025 at 8:22 PM
RESEARCH | T Feng, Q Luo, J Yun et al (@mdanderson.bsky.social)
The combination of glucose and fructose in sugar-sweetened beverages promotes colorectal cancer metastasis via sorbitol dehydrogenase 🧪
www.nature.com/articles/s42...
The combination of glucose and fructose in sugar-sweetened beverages promotes colorectal cancer metastasis via sorbitol dehydrogenase 🧪
www.nature.com/articles/s42...
The weekly Metabolism driving cancer organotropism (biomed.news/bims-metorg/...) and Metabolites-driven PTMs focusing on cancer (biomed.news/bims-prolim/...) at @biomednews.bsky.social are out ☺️
bims-metorg 2025-11-02 papers
biomed.news
November 3, 2025 at 8:27 AM
The weekly Metabolism driving cancer organotropism (biomed.news/bims-metorg/...) and Metabolites-driven PTMs focusing on cancer (biomed.news/bims-prolim/...) at @biomednews.bsky.social are out ☺️
Reposted by Bruna Martins Garcia
It is a big honor to receive this Award "Premio Nacional de Investigación 2024". This is also a recognition for colleagues, mentors and friends that worked with me along the way. Hope this inspires young scientists that come after.
Thanks for the beautiful day🥰😊 www.youtube.com/watch?v=oSQP...
Thanks for the beautiful day🥰😊 www.youtube.com/watch?v=oSQP...
July 4, 2025 at 8:59 AM
It is a big honor to receive this Award "Premio Nacional de Investigación 2024". This is also a recognition for colleagues, mentors and friends that worked with me along the way. Hope this inspires young scientists that come after.
Thanks for the beautiful day🥰😊 www.youtube.com/watch?v=oSQP...
Thanks for the beautiful day🥰😊 www.youtube.com/watch?v=oSQP...
The weekly Metabolites-driven PTMs focusing on cancer @biomednews.bsky.social is out ☺️ biomed.news/bims-prolim/...
Highlight:
portlandpress.com/biochemsoctr...
Highlight:
portlandpress.com/biochemsoctr...
The rise of AMPylation: from bacterial beginnings to modern implications in health and disease
Protein AMPylation is a post-translational modification in which adenosine monophosphate (AMP) from ATP is covalently attached to a target protein via a phosphodiester bond. This reaction is catalyzed...
portlandpress.com
July 14, 2025 at 7:09 AM
The weekly Metabolites-driven PTMs focusing on cancer @biomednews.bsky.social is out ☺️ biomed.news/bims-prolim/...
Highlight:
portlandpress.com/biochemsoctr...
Highlight:
portlandpress.com/biochemsoctr...
Reposted by Bruna Martins Garcia
www.sciencedirect.com/science/arti...
Have a look at our views on the recent paper about fumarate and mitophagy.
Have a look at our views on the recent paper about fumarate and mitophagy.
Fumarate hits the brakes on mitophagy
In this issue of Molecular Cell, Ham et al.1 demonstrate that the metabolite fumarate, when accumulated in cells, can influence mitochondrial quality …
www.sciencedirect.com
June 19, 2025 at 3:11 PM
www.sciencedirect.com/science/arti...
Have a look at our views on the recent paper about fumarate and mitophagy.
Have a look at our views on the recent paper about fumarate and mitophagy.
What a wonderful way to start a holiday!
First Spanish Fellowship ✔️
I am looking forward to developing the project with the amazing @alteamanzanolab.bsky.social at @cabimer.bsky.social in the pretty Seville 😍
First Spanish Fellowship ✔️
I am looking forward to developing the project with the amazing @alteamanzanolab.bsky.social at @cabimer.bsky.social in the pretty Seville 😍
June 19, 2025 at 8:50 AM
What a wonderful way to start a holiday!
First Spanish Fellowship ✔️
I am looking forward to developing the project with the amazing @alteamanzanolab.bsky.social at @cabimer.bsky.social in the pretty Seville 😍
First Spanish Fellowship ✔️
I am looking forward to developing the project with the amazing @alteamanzanolab.bsky.social at @cabimer.bsky.social in the pretty Seville 😍
The weekly Metabolites-driven PTMs focusing on cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
June 9, 2025 at 7:16 AM
The weekly Metabolites-driven PTMs focusing on cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
Reposted by Bruna Martins Garcia
We @morgridgeinstitute.bsky.social, in partnership with
@bmolchem.bsky.social , are looking for a great new metabolism researcher to join our @morgridgemeta.bsky.social team. Please see ad below and send along to your colleagues!
morgridge.org/job-posting/...
@bmolchem.bsky.social , are looking for a great new metabolism researcher to join our @morgridgemeta.bsky.social team. Please see ad below and send along to your colleagues!
morgridge.org/job-posting/...
Assistant Professor in Metabolism Research - Morgridge Institute for Research
The Morgridge Institute for Research, in partnership with the Department of Biomolecular Chemistry at the University of Wisconsin-Madison, seeks a joint tenure track assistant professor to lead a vibr...
morgridge.org
May 27, 2025 at 4:35 PM
We @morgridgeinstitute.bsky.social, in partnership with
@bmolchem.bsky.social , are looking for a great new metabolism researcher to join our @morgridgemeta.bsky.social team. Please see ad below and send along to your colleagues!
morgridge.org/job-posting/...
@bmolchem.bsky.social , are looking for a great new metabolism researcher to join our @morgridgemeta.bsky.social team. Please see ad below and send along to your colleagues!
morgridge.org/job-posting/...
The weekly Metabolites-driven PTMs focusing on cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
Highlights (1/2): pmc.ncbi.nlm.nih.gov/articles/PMC...
Highlights (2/2): www.science.org/doi/10.1126/...
Highlights (1/2): pmc.ncbi.nlm.nih.gov/articles/PMC...
Highlights (2/2): www.science.org/doi/10.1126/...
Dual Regulation of Sprouty 4 Palmitoylation by ZDHHC7 and Palmitoyl-Protein Thioesterase 1: A Potential Therapeutic Strategy for Cisplatin-Resistant Osteosarcoma
Background: Osteosarcoma (OS) is a primary malignant bone tumor predominantly affecting adolescents. Chemotherapeutic agents, such as cisplatin, are commonly used in OS treatment; however, drug resist...
pmc.ncbi.nlm.nih.gov
June 1, 2025 at 12:56 PM
The weekly Metabolites-driven PTMs focusing on cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
Highlights (1/2): pmc.ncbi.nlm.nih.gov/articles/PMC...
Highlights (2/2): www.science.org/doi/10.1126/...
Highlights (1/2): pmc.ncbi.nlm.nih.gov/articles/PMC...
Highlights (2/2): www.science.org/doi/10.1126/...
One month left to register for the 2025 Early Career Researchers Conference!
In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.
Don't miss it: eacr.org/conference/e...
In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.
Don't miss it: eacr.org/conference/e...
One month left to register for the 2025 Early Career Researchers Conference!
In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.
Don't miss it: eacr.org/conference/e...
In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.
Don't miss it: eacr.org/conference/e...
May 12, 2025 at 11:01 AM
One month left to register for the 2025 Early Career Researchers Conference!
In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.
Don't miss it: eacr.org/conference/e...
In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.
Don't miss it: eacr.org/conference/e...
The weekly Metabolites-driven PTMs focusing on cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
Highlights (1/2): Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics molecular-cancer.biomedcentral.com/articles/10....
Highlights (1/2): Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics molecular-cancer.biomedcentral.com/articles/10....
Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics - Molecular Cancer
Protein lipidation is a pivotal post-translational modification that increases protein hydrophobicity and influences their function, localization, and interaction network. Emerging evidence has shown ...
molecular-cancer.biomedcentral.com
May 11, 2025 at 12:29 PM
The weekly Metabolites-driven PTMs focusing on cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
Highlights (1/2): Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics molecular-cancer.biomedcentral.com/articles/10....
Highlights (1/2): Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics molecular-cancer.biomedcentral.com/articles/10....
The weekly Metabolites-driven PTMs Biomed News is out ☺️ biomed.news/bims-prolim/...
Highlights (1/2): Engineered depalmitoylases enable selective manipulation of protein localization and function www.nature.com/articles/s41...
Highlights (1/2): Engineered depalmitoylases enable selective manipulation of protein localization and function www.nature.com/articles/s41...
Engineered depalmitoylases enable selective manipulation of protein localization and function - Nature Communications
Dynamic palmitoylation modulates protein localization and function. Here, Jayaraman et al develop a toolkit of engineered depalmitoylases to manipulate protein function with spatial, temporal, and sub...
www.nature.com
April 20, 2025 at 7:12 PM
The weekly Metabolites-driven PTMs Biomed News is out ☺️ biomed.news/bims-prolim/...
Highlights (1/2): Engineered depalmitoylases enable selective manipulation of protein localization and function www.nature.com/articles/s41...
Highlights (1/2): Engineered depalmitoylases enable selective manipulation of protein localization and function www.nature.com/articles/s41...
Reposted by Bruna Martins Garcia
"Many scientists know from the start that they want to be academic researchers. But for others the path unfolds gradually, with spurts of doubt and uncertainty along the way. In a way, that’s fitting." #ScienceWorkingLife scim.ag/43Ph9Ei
April 14, 2025 at 7:07 PM
"Many scientists know from the start that they want to be academic researchers. But for others the path unfolds gradually, with spurts of doubt and uncertainty along the way. In a way, that’s fitting." #ScienceWorkingLife scim.ag/43Ph9Ei
Reposted by Bruna Martins Garcia
How can we fix gender #inequality in #academia in 3 steps? Suggestions from our article in @elife.bsky.social with Gabriella Damasceno, @danielahoss.bsky.social, Alexandra Weyrich, a product of the iDiv Female Scientists initiative www.idiv.de/striving-for...
elifesciences.org/articles/105...
elifesciences.org/articles/105...
Equity, Diversity and Inclusion: Improving gender equity in academia depends on the workplace environment
The authors recommend actions that can be taken by individuals, institutions and policymakers to promote gender equity.
elifesciences.org
April 14, 2025 at 9:50 AM
How can we fix gender #inequality in #academia in 3 steps? Suggestions from our article in @elife.bsky.social with Gabriella Damasceno, @danielahoss.bsky.social, Alexandra Weyrich, a product of the iDiv Female Scientists initiative www.idiv.de/striving-for...
elifesciences.org/articles/105...
elifesciences.org/articles/105...
"We have to be willing to fail, to be wrong — to start over again with lessons learned."
www.ted.com/talks/angela...
www.ted.com/talks/angela...
Grit: The power of passion and perseverance
Leaving a high-flying job in consulting, Angela Lee Duckworth took a job teaching math to seventh graders in a New York public school. She quickly realized that IQ wasn't the only thing separating the...
www.ted.com
April 14, 2025 at 5:00 AM
"We have to be willing to fail, to be wrong — to start over again with lessons learned."
www.ted.com/talks/angela...
www.ted.com/talks/angela...
This week Metabolites-driven PTMs (focused on lipidation), metabolism, and cancer Biomed News is out ☺️
biomed.news/bims-prolim/...
biomed.news/bims-prolim/...
bims-prolim 2025-04-13 papers
biomed.news
April 13, 2025 at 8:09 AM
This week Metabolites-driven PTMs (focused on lipidation), metabolism, and cancer Biomed News is out ☺️
biomed.news/bims-prolim/...
biomed.news/bims-prolim/...
Want to learn more about cancer models that span in vitro investigations to in vivo cancer biology? Join the EACR in Essen from 23-25 Sept 2025 for Goodbye Flat Biology! www.eacr.org/conference/goodbyeflatbiology2025 #CancerResearch #Oncology
After a sold-out 2023 event, Goodbye Flat Biology has moved to a larger venue in Essen, Germany to make sure more of you can join us for what promises to be another fantastic event!
Join us for 3 days of excellent science and networking:
eacr.org/conference/g...
Join us for 3 days of excellent science and networking:
eacr.org/conference/g...
April 11, 2025 at 7:48 AM
Want to learn more about cancer models that span in vitro investigations to in vivo cancer biology? Join the EACR in Essen from 23-25 Sept 2025 for Goodbye Flat Biology! www.eacr.org/conference/goodbyeflatbiology2025 #CancerResearch #Oncology
This week, Metabolites-driven PTMs (focused on lipidation), metabolism, and cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
April 6, 2025 at 12:30 PM
This week, Metabolites-driven PTMs (focused on lipidation), metabolism, and cancer Biomed News is out ☺️ biomed.news/bims-prolim/...
Reposted by Bruna Martins Garcia
Online Now: Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
The overall impact of arginine metabolism in tumor progression remains unclear. Using clinical analysis, scRNA-seq, and animal models, Zhu et al. identify cancer cell-macrophage metabolic interplay as the key driver of arginine’s impact in breast cancer. This study provides mechanistic insights into leveraging arginine metabolism to enhance antitumor immunity.
dlvr.it
April 4, 2025 at 6:51 PM
Online Now: Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
Reposted by Bruna Martins Garcia
NEW content online!
Blocking cholesterol biosynthesis to clean out cancer
Nature Reviews Cancer, Published online: 04 April 2025; doi:10.1038/s41568-025-00816-9The mechanisms of how pH-dependent cell death, alkaliptosis, is regulated are incompletely understood. Chen et al. now demonstrate that the cholesterol biosynthesis protein CYP51A1 suppresses alkaliptosis induced by the opioid analgesic JTC801.
www.nature.com
April 4, 2025 at 2:32 PM
NEW content online!
This week, Metabolites-driven PTMs (focused on lipidation), metabolism, and cancer Biomed News is out ☺️ biomed.news/bims-prolim/... with 2 highlights:
pubmed.ncbi.nlm.nih.gov/40121269/
www.embopress.org/doi/full/10....
pubmed.ncbi.nlm.nih.gov/40121269/
www.embopress.org/doi/full/10....
S-palmitoylation modulates ATG2-dependent non-vesicular lipid transport during starvation-induced autophagy | The EMBO Journal
imageimageATG2 is essential for autophagosome biogenesis as it transfers membrane material from
the endoplasmic reticulum to growing phagophores. This study reveals that S-palmitoylation
dynamically r...
www.embopress.org
March 31, 2025 at 7:53 AM
This week, Metabolites-driven PTMs (focused on lipidation), metabolism, and cancer Biomed News is out ☺️ biomed.news/bims-prolim/... with 2 highlights:
pubmed.ncbi.nlm.nih.gov/40121269/
www.embopress.org/doi/full/10....
pubmed.ncbi.nlm.nih.gov/40121269/
www.embopress.org/doi/full/10....
This issue looks great! And has my supervisor @alteamanzanolab.bsky.social new review “Metabolic interplays between the tumour and the host shape the tumour macroenvironment”! #cancer #metabolism
🚨 Our April issue is LIVE! 🌻 🌦️
It features articles on:
- Dendritic cell maturation in cancer
- Cross-priming in cancer immunology & immunotherapy
- Metabolic interplays between tumour & host
- A 'cells to society' research framework for appendix cancer
📖👉
It features articles on:
- Dendritic cell maturation in cancer
- Cross-priming in cancer immunology & immunotherapy
- Metabolic interplays between tumour & host
- A 'cells to society' research framework for appendix cancer
📖👉
Nature Reviews Cancer - Volume 25 Issue 4, April 2025
Hunting a rare cancer, inspired by the Expert Recommendation on p293.
bit.ly
March 28, 2025 at 4:49 PM
This issue looks great! And has my supervisor @alteamanzanolab.bsky.social new review “Metabolic interplays between the tumour and the host shape the tumour macroenvironment”! #cancer #metabolism
Reposted by Bruna Martins Garcia
Fue un placer compartir con la familia de CSIC nuestros trabajos en cáncer metastásico y visitar la Residencia de Estudiantes de @csic.es
It was a pleasure to share our work on metastatic cancer with the CSIC family and visit the Residencia de Estudiantes. Thank you for having me!
It was a pleasure to share our work on metastatic cancer with the CSIC family and visit the Residencia de Estudiantes. Thank you for having me!
Hoy nos ha impresionado la conferencia de la investigadora Patricia Altea sobre posibles dianas del Cáncer Metastásico
Nuestra joven colega del CABIMER- @CSIC
es ya Premio Nacional de Investigación y tiene una impresionante trayectoria internacional
premiosnacionales.csic.es/patricia-alt...
Nuestra joven colega del CABIMER- @CSIC
es ya Premio Nacional de Investigación y tiene una impresionante trayectoria internacional
premiosnacionales.csic.es/patricia-alt...
March 27, 2025 at 6:42 AM
Fue un placer compartir con la familia de CSIC nuestros trabajos en cáncer metastásico y visitar la Residencia de Estudiantes de @csic.es
It was a pleasure to share our work on metastatic cancer with the CSIC family and visit the Residencia de Estudiantes. Thank you for having me!
It was a pleasure to share our work on metastatic cancer with the CSIC family and visit the Residencia de Estudiantes. Thank you for having me!
Reposted by Bruna Martins Garcia
Good morning, all. The first curated issue of papers in #cancermetabolism and #mitochondrialbiology this spring is out. Don't miss it!
biomed.news/bims-camemi/...
@biomednews.bsky.social
"Not everything that is faced can be changed, but nothing can be changed that is not faced." James Baldwin
biomed.news/bims-camemi/...
@biomednews.bsky.social
"Not everything that is faced can be changed, but nothing can be changed that is not faced." James Baldwin
a stick figure is sitting on a stool reading a book
ALT: a stick figure is sitting on a stool reading a book
media.tenor.com
March 23, 2025 at 6:12 AM
Good morning, all. The first curated issue of papers in #cancermetabolism and #mitochondrialbiology this spring is out. Don't miss it!
biomed.news/bims-camemi/...
@biomednews.bsky.social
"Not everything that is faced can be changed, but nothing can be changed that is not faced." James Baldwin
biomed.news/bims-camemi/...
@biomednews.bsky.social
"Not everything that is faced can be changed, but nothing can be changed that is not faced." James Baldwin