Boris Bogdanow
@bogdanow.bsky.social
Linking protein structure to function and mechanisms in virology. https://virologie-ccm.charite.de/forschung/ag_bogdanow
Pinned
Boris Bogdanow
@bogdanow.bsky.social
· Jul 22
Structural host-virus interactome profiling of intact infected cells - Nature Communications
Virus-host protein-protein interactions are fundamental to viral pathogenesis, yet few are structurally resolved. Here, the authors combine cross-linking mass spectrometry, bio-orthogonal labeling and...
www.nature.com
Check out Structural Host–Virus Interactome Profiling (SHVIP) in intact cells infected with Herpes Simplex Virus type 1 (HSV-1)! Now published!
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
Reposted by Boris Bogdanow
It’s out! Using cryo-ET in Dicty cells, we take a fresh in situ look at vaults. Surprisingly, we uncover vaults associated with ER and NE membranes, and find that many vaults enclose ribosomes in defined orientations, opening new avenues to their cellular function! www.biorxiv.org/lookup/conte...
December 16, 2025 at 8:17 AM
It’s out! Using cryo-ET in Dicty cells, we take a fresh in situ look at vaults. Surprisingly, we uncover vaults associated with ER and NE membranes, and find that many vaults enclose ribosomes in defined orientations, opening new avenues to their cellular function! www.biorxiv.org/lookup/conte...
Reposted by Boris Bogdanow
IsoNet2 determines cellular structures at submolecular resolution without averaging https://www.biorxiv.org/content/10.64898/2025.12.09.693325v1
December 11, 2025 at 11:32 AM
IsoNet2 determines cellular structures at submolecular resolution without averaging https://www.biorxiv.org/content/10.64898/2025.12.09.693325v1
Reposted by Boris Bogdanow
Excited to share: A Nature Communications study led by Fan Liu (Absea SAB Chair, FMP Berlin) introduces SHVIP—a method revealing 739 virus–host PPIs in intact HSV-1 infected cells.
It preserves membrane structure & uses AlphaFold to interpret complex networks.
🔗
It preserves membrane structure & uses AlphaFold to interpret complex networks.
🔗
Structural host-virus interactome profiling of intact infected cells - Nature Communications
Virus-host protein-protein interactions are fundamental to viral pathogenesis, yet few are structurally resolved. Here, the authors combine cross-linking mass spectrometry, bio-orthogonal labeling…
www.nature.com
August 7, 2025 at 9:30 AM
Excited to share: A Nature Communications study led by Fan Liu (Absea SAB Chair, FMP Berlin) introduces SHVIP—a method revealing 739 virus–host PPIs in intact HSV-1 infected cells.
It preserves membrane structure & uses AlphaFold to interpret complex networks.
🔗
It preserves membrane structure & uses AlphaFold to interpret complex networks.
🔗
Check out Structural Host–Virus Interactome Profiling (SHVIP) in intact cells infected with Herpes Simplex Virus type 1 (HSV-1)! Now published!
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
Structural host-virus interactome profiling of intact infected cells - Nature Communications
Virus-host protein-protein interactions are fundamental to viral pathogenesis, yet few are structurally resolved. Here, the authors combine cross-linking mass spectrometry, bio-orthogonal labeling and...
www.nature.com
July 22, 2025 at 8:15 AM
Check out Structural Host–Virus Interactome Profiling (SHVIP) in intact cells infected with Herpes Simplex Virus type 1 (HSV-1)! Now published!
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
📄 www.nature.com/articles/s41...
#LoveVirology #TeamMassSpec
Reposted by Boris Bogdanow
Building atomic models to cryo-EM maps of huge molecules is intimidating: crowded, uncertain copy numbers, variable resolution ...
Fan Liu and team incl us, show how cross-linking MS can be used to build novel models of unknown complexes, like a giant Melbourne virus
biorxiv.org/content/10.1...
Fan Liu and team incl us, show how cross-linking MS can be used to build novel models of unknown complexes, like a giant Melbourne virus
biorxiv.org/content/10.1...
June 19, 2025 at 1:54 PM
Building atomic models to cryo-EM maps of huge molecules is intimidating: crowded, uncertain copy numbers, variable resolution ...
Fan Liu and team incl us, show how cross-linking MS can be used to build novel models of unknown complexes, like a giant Melbourne virus
biorxiv.org/content/10.1...
Fan Liu and team incl us, show how cross-linking MS can be used to build novel models of unknown complexes, like a giant Melbourne virus
biorxiv.org/content/10.1...