@biomatik.bsky.social
Congratulations to Xi Qiao & the Ventelä team! They discovered that in head & neck cancer, they found that tumors with high LIMA1-alpha expression respond poorly to surgery and promote metastasis. This biomarker may guide more personalized cancer treatments.
🔗 doi.org/10.1038/s443...
#Oncology
🔗 doi.org/10.1038/s443...
#Oncology
September 8, 2025 at 8:34 PM
Congratulations to Xi Qiao & the Ventelä team! They discovered that in head & neck cancer, they found that tumors with high LIMA1-alpha expression respond poorly to surgery and promote metastasis. This biomarker may guide more personalized cancer treatments.
🔗 doi.org/10.1038/s443...
#Oncology
🔗 doi.org/10.1038/s443...
#Oncology
Reposted
Just donated a few $$ to keep people informed on climate. Felt like a good way to start the day. 🧪
Scientists breathe new life into climate website after shutdown under Trump
Climate.gov, which went dark this summer, to be revived by volunteers as climate.us with expanded mission
www.theguardian.com
September 2, 2025 at 7:02 PM
Just donated a few $$ to keep people informed on climate. Felt like a good way to start the day. 🧪
TIL cat dementia is a thing
Feline dementia shows brain changes, like amyloid-beta buildup and synapse loss, strikingly similar to human Alzheimer’s, offering new insight into brain aging and potential treatments.
How do you keep your brain sharp? 🐈⬛🧠🧪
#Cat #Brain #Alzheimers
How do you keep your brain sharp? 🐈⬛🧠🧪
#Cat #Brain #Alzheimers
September 2, 2025 at 8:18 PM
TIL cat dementia is a thing
Applause to Amir Namvar Vansofla and the Shahmaleki Lab! Shigella infections kill hundreds of thousands yearly. This team designed a vaccine with multiple epitopes that protected mice from diverse Shigella strains. A big leap for global health.
🔗 doi.org/10.1016/j.ji...
#GlobalHealth #Vaccine
🔗 doi.org/10.1016/j.ji...
#GlobalHealth #Vaccine
September 1, 2025 at 8:34 PM
Applause to Amir Namvar Vansofla and the Shahmaleki Lab! Shigella infections kill hundreds of thousands yearly. This team designed a vaccine with multiple epitopes that protected mice from diverse Shigella strains. A big leap for global health.
🔗 doi.org/10.1016/j.ji...
#GlobalHealth #Vaccine
🔗 doi.org/10.1016/j.ji...
#GlobalHealth #Vaccine
Bravo to Alexander Fenton & Jean Chung! They discovered that Bruton's tyrosine kinase (Btk) assembles on membranes via weak proline-rich region (PRR)–SH3 interactions, enabling phase separation. Btk is a key player in B-cell development and a target in leukemia therapy.
🔗 buff.ly/KlAKcub
#Leukemia
🔗 buff.ly/KlAKcub
#Leukemia
August 25, 2025 at 8:34 PM
Bravo to Alexander Fenton & Jean Chung! They discovered that Bruton's tyrosine kinase (Btk) assembles on membranes via weak proline-rich region (PRR)–SH3 interactions, enabling phase separation. Btk is a key player in B-cell development and a target in leukemia therapy.
🔗 buff.ly/KlAKcub
#Leukemia
🔗 buff.ly/KlAKcub
#Leukemia
Reposted
Hey everybody! @drjuliawester.bsky.social and I have a new paper!
We surveyed over 800 scientists, science communicators, and science educators who use social media.
Conclusion: Scientists no longer find Twitter useful or pleasant, and many have switched to Bluesky! 🧪🌎🦑
doi.org/10.1093/icb/...
We surveyed over 800 scientists, science communicators, and science educators who use social media.
Conclusion: Scientists no longer find Twitter useful or pleasant, and many have switched to Bluesky! 🧪🌎🦑
doi.org/10.1093/icb/...
Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky
Synopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For
doi.org
August 19, 2025 at 2:34 PM
Hey everybody! @drjuliawester.bsky.social and I have a new paper!
We surveyed over 800 scientists, science communicators, and science educators who use social media.
Conclusion: Scientists no longer find Twitter useful or pleasant, and many have switched to Bluesky! 🧪🌎🦑
doi.org/10.1093/icb/...
We surveyed over 800 scientists, science communicators, and science educators who use social media.
Conclusion: Scientists no longer find Twitter useful or pleasant, and many have switched to Bluesky! 🧪🌎🦑
doi.org/10.1093/icb/...
Linda Brent & Florian Roeber find that low-dose testosterone safely restores hormonal balance in neutered dogs, potentially preventing "spay-neuter syndrome" and improving long-term health outcomes.
🔗 buff.ly/aWprWB5
#VeterinaryMedicine #Endocrinology
🔗 buff.ly/aWprWB5
#VeterinaryMedicine #Endocrinology
Safety and dosing of testosterone for hormone restoration in neutered dogs - BMC Veterinary Research
A lack of safety and dosing information on restoring hormone levels in neutered dogs has hindered treatment of spay-neuter syndrome, the diverse set of health and behavior conditions resulting from…
doi.org
August 18, 2025 at 8:34 PM
Linda Brent & Florian Roeber find that low-dose testosterone safely restores hormonal balance in neutered dogs, potentially preventing "spay-neuter syndrome" and improving long-term health outcomes.
🔗 buff.ly/aWprWB5
#VeterinaryMedicine #Endocrinology
🔗 buff.ly/aWprWB5
#VeterinaryMedicine #Endocrinology
Nicholas Vitari & team reveal that short-term morphine disrupts the gut microbiome & triggers immune complement activation. This suggests opioids may suppress homeostasis via host-microbe interactions—critical for chronic pain patients.
🔗 buff.ly/xeGEH8Q
#Immunology #Microbiota
🔗 buff.ly/xeGEH8Q
#Immunology #Microbiota
August 11, 2025 at 12:19 PM
Nicholas Vitari & team reveal that short-term morphine disrupts the gut microbiome & triggers immune complement activation. This suggests opioids may suppress homeostasis via host-microbe interactions—critical for chronic pain patients.
🔗 buff.ly/xeGEH8Q
#Immunology #Microbiota
🔗 buff.ly/xeGEH8Q
#Immunology #Microbiota
Congratulations to Antonius Chrisnandy from The Lutolf Lab who showed that intestinal stem cells make their own ECM niche, enabling organoid growth without animal-derived laminin. A big step toward defined, scalable culture systems.
🔗 doi.org/10.1016/j.de...
#StemCells #OrganoidResearch
🔗 doi.org/10.1016/j.de...
#StemCells #OrganoidResearch
An extracellular matrix niche secreted by epithelial cells drives intestinal organoid formation
Intestinal organoids have become an important model system in basic and translational research, but their culture typically relies on an ill-defined l…
doi.org
August 8, 2025 at 2:37 PM
Congratulations to Antonius Chrisnandy from The Lutolf Lab who showed that intestinal stem cells make their own ECM niche, enabling organoid growth without animal-derived laminin. A big step toward defined, scalable culture systems.
🔗 doi.org/10.1016/j.de...
#StemCells #OrganoidResearch
🔗 doi.org/10.1016/j.de...
#StemCells #OrganoidResearch
Many congratulations to Samrin Habbani and Sayeh Dowlatshahi from the Mohammed lab on another awesome discovery! They identified protein biomarkers for early cervical cancer detection. This could improve screening in underserved areas.
🔗https://buff.ly/YS59dny
#Cancer #Diagnostics #GlobalHealth
🔗https://buff.ly/YS59dny
#Cancer #Diagnostics #GlobalHealth
August 6, 2025 at 1:36 AM
Many congratulations to Samrin Habbani and Sayeh Dowlatshahi from the Mohammed lab on another awesome discovery! They identified protein biomarkers for early cervical cancer detection. This could improve screening in underserved areas.
🔗https://buff.ly/YS59dny
#Cancer #Diagnostics #GlobalHealth
🔗https://buff.ly/YS59dny
#Cancer #Diagnostics #GlobalHealth
Many congratulations to Saranya Reghupaty and Laetitia Voilquin-Coassolo from the Svensson team on another awesome discovery! They found Ism1 loss triggers insulin resistance. This could point to new metabolic disease treatments.
🔗https://buff.ly/NTGFbpY
#Metabolism #Diabetes
🔗https://buff.ly/NTGFbpY
#Metabolism #Diabetes
August 5, 2025 at 10:11 PM
Many congratulations to Saranya Reghupaty and Laetitia Voilquin-Coassolo from the Svensson team on another awesome discovery! They found Ism1 loss triggers insulin resistance. This could point to new metabolic disease treatments.
🔗https://buff.ly/NTGFbpY
#Metabolism #Diabetes
🔗https://buff.ly/NTGFbpY
#Metabolism #Diabetes
Congrats to Serena Muratcioglu from the Kuriyan Lab! They found that TEL-ABL fusion proteins drive resistance to asciminib by forming oligomers. These insights into fusion oncoproteins and drug-resistant leukemias.
🔗 doi.org/10.1126/scis...
#Leukemia #CancerSignaling
🔗 doi.org/10.1126/scis...
#Leukemia #CancerSignaling
Autophosphorylation of oncoprotein TEL-ABL in myeloid and lymphoid cells confers resistance to the allosteric ABL inhibitor asciminib
Oligomerization renders the oncoprotein TEL-ABL insensitive to the ABL inhibitor asciminib.
doi.org
August 4, 2025 at 10:30 PM
Congrats to Serena Muratcioglu from the Kuriyan Lab! They found that TEL-ABL fusion proteins drive resistance to asciminib by forming oligomers. These insights into fusion oncoproteins and drug-resistant leukemias.
🔗 doi.org/10.1126/scis...
#Leukemia #CancerSignaling
🔗 doi.org/10.1126/scis...
#Leukemia #CancerSignaling
It's maybe not so surprising to anyone familiar with inflammatory immune responses that immunology and oncology are so tightly linked
A study in Nature shows that respiratory viruses trigger metastatic breast cancer cells to proliferate in lungs in mouse models of breast cancer. These findings are supported by human observational data. go.nature.com/4l7NZ8l #medsky 🧪
August 1, 2025 at 7:05 PM
It's maybe not so surprising to anyone familiar with inflammatory immune responses that immunology and oncology are so tightly linked
I didn't normally use twitter until I started managing Biomatik's social media
What stood out most that there's so many more antivaxxers than I thought
What stood out most that there's so many more antivaxxers than I thought
August 1, 2025 at 7:04 PM
I didn't normally use twitter until I started managing Biomatik's social media
What stood out most that there's so many more antivaxxers than I thought
What stood out most that there's so many more antivaxxers than I thought
Reposted
July 31, 2025 at 9:27 PM
Reposted
OMFG THIS IS GOOD NEWS! Looks like our senators are starting to understand the potential impacts of the proposed budget cuts. There was bipartisan support for a $400 mil INCREASE in the NIH budget, including preserving all 27 institutes within the NIH.
🧪🔗 www.science.org/content/arti...
🧪🔗 www.science.org/content/arti...
With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency
Republicans on spending committee push back against proposed reorganization and overhead cuts
www.science.org
July 31, 2025 at 10:34 PM
OMFG THIS IS GOOD NEWS! Looks like our senators are starting to understand the potential impacts of the proposed budget cuts. There was bipartisan support for a $400 mil INCREASE in the NIH budget, including preserving all 27 institutes within the NIH.
🧪🔗 www.science.org/content/arti...
🧪🔗 www.science.org/content/arti...
This is amazing work- enantiomer selection for proteins opens up tons of new biosynthesis options long term
Fantastic work by the Ward lab to repurpose cytochrome #P450 enzymes for a new-to-nature asymmetric metal-catalysed H atom transfer! Just released
@Nature
: doi.org/10.1038/s415.... A must read!🧪
@Nature
: doi.org/10.1038/s415.... A must read!🧪
Repurposing haemoproteins for asymmetric metal-catalysed H atom transfer - Nature
Cytochrome P450 enzymes can be repurposed to catalyse asymmetric metal–hydride hydrogen atom transfer, a new-to-nature reaction.
doi.org
August 1, 2025 at 6:46 PM
This is amazing work- enantiomer selection for proteins opens up tons of new biosynthesis options long term
Reposted
A technology feature in Nature describes how enzyme-based techniques and refinements in organic chemistry are easing the generation of extended DNA sequences. 🧬 🧪
Made-to-order DNA goes big: new tech doubles size of custom genetic sequences
Enzyme-based techniques and refinements in organic chemistry ease the generation of extended DNA sequences.
go.nature.com
August 1, 2025 at 1:11 AM
A technology feature in Nature describes how enzyme-based techniques and refinements in organic chemistry are easing the generation of extended DNA sequences. 🧬 🧪
Many congratulations to Jessica Regan and Christian DeJarnette from the Palmer lab on another awesome discovery! They found PanK is a key vulnerability in cancer cells. This could spark new selective cancer therapies.
🔗https://doi.org/10.1016/j.chembiol.2025.04.007
#CancerTherapy
🔗https://doi.org/10.1016/j.chembiol.2025.04.007
#CancerTherapy
July 28, 2025 at 8:34 PM
Many congratulations to Jessica Regan and Christian DeJarnette from the Palmer lab on another awesome discovery! They found PanK is a key vulnerability in cancer cells. This could spark new selective cancer therapies.
🔗https://doi.org/10.1016/j.chembiol.2025.04.007
#CancerTherapy
🔗https://doi.org/10.1016/j.chembiol.2025.04.007
#CancerTherapy
Many congratulations to Luis Ontiveros-Padilla and Dylan Hendy from the @kristy-ainslie-lab.bsky.social on another awesome discovery! They developed a nanocomplex intranasal flu vaccine effective across strains. This could help create a universal, needle-free flu shot.
🔗 doi.org/10.1016/j.jc...
🔗 doi.org/10.1016/j.jc...
July 24, 2025 at 12:19 AM
Many congratulations to Luis Ontiveros-Padilla and Dylan Hendy from the @kristy-ainslie-lab.bsky.social on another awesome discovery! They developed a nanocomplex intranasal flu vaccine effective across strains. This could help create a universal, needle-free flu shot.
🔗 doi.org/10.1016/j.jc...
🔗 doi.org/10.1016/j.jc...
Many congratulations to Mohamed Allam and Yahia Amin from the Ali lab on another awesome discovery! They found MSCs help repair lead-induced DNA damage in testicular cancer. This could support regenerative therapies for toxin exposure.
🔗 doi.org/10.1186/s406...
#StemCells
🔗 doi.org/10.1186/s406...
#StemCells
Mesenchymal stem cells reduce the genotoxic effect of lead acetate in the testis of male rats and induce testicular cellular proliferation indicated by 16S rRNA sequence, increase the proliferation marker Ki-67 and a reduction in the apoptosis marker caspase-3 - Biological Research
Background Lead is a ubiquitous environmental and industrial pollutant with worldwide health problems. Lead acetate toxicity induces both genotoxic effects and apoptosis. The present study aimed to…
doi.org
July 21, 2025 at 8:34 PM
Many congratulations to Mohamed Allam and Yahia Amin from the Ali lab on another awesome discovery! They found MSCs help repair lead-induced DNA damage in testicular cancer. This could support regenerative therapies for toxin exposure.
🔗 doi.org/10.1186/s406...
#StemCells
🔗 doi.org/10.1186/s406...
#StemCells