Benoit Pons
benoitjpons.bsky.social
Benoit Pons
@benoitjpons.bsky.social
Lecturer in bacterial genomics at Université Toulouse III - Paul Sabatier
Research in phage-bacteria co-evolution at LMGM @cbitoulouse.bsky.social
he/him
How do bacteria choose what type of defences to use against phages? We explored that question in the last paper I worked on as a postdoc at the Uni of Exeter @uniofexeteresi.bsky.social with Stineke van Houte, Stefano Pagliara and Edze Westra (not on Bluesky)
doi.org/10.1098/rstb...
Phage provoke growth delays and SOS response induction despite CRISPR-Cas protection | Philosophical Transactions of the Royal Society B: Biological Sciences
Bacteria evolve resistance against their phage foes with a wide range of resistance strategies whose costs and benefits depend on the level of protection they confer and on the costs for maintainance....
doi.org
September 4, 2025 at 4:02 PM
Reposted by Benoit Pons
Can CRISPR-Cas systems target any phage? Yes, no, it depends? What does it depend on? The second paper from my PhD came out today in a special issue of Phil Trans B on the ecology and evolution of bacterial immune systems
doi.org/10.1098/rstb...
Phage susceptibility to a minimal, modular synthetic CRISPR-Cas system in Pseudomonas aeruginosa is nutrient dependent | Philosophical Transactions of the Royal Society B: Biological Sciences
CRISPR-Cas systems can provide adaptive, heritable immunity to their prokaryotic hosts against invading genetic material such as phages. It is clear that the importance of acquiring CRISPR-Cas immunit...
doi.org
September 4, 2025 at 11:32 AM
Reposted by Benoit Pons
PhD opportunity, please share:

We are looking for a prospective PhD student to start in October 2026 who is excited about bacteria (Klebsiella pneumoniae), how they interact, and how they exchange DNA.
All details can be found on the funder website 👉 gw4biomed.ac.uk/developing-c...
Developing CRISPR-Cas antimicrobials to tackle antibiotic resistance spread in Klebsiella pneumoniae - GW4 BioMed MRC DTP
Project Code MRCIIAR26Ex van Houte Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance (AMR) poses a ...
gw4biomed.ac.uk
September 2, 2025 at 9:48 AM
Reposted by Benoit Pons
The team is growing fast!
🎉 Congratulations to Léa Masson on receiving a PhD fellowship from the BSB doctoral school @universitetoulouse.bsky.social 👏

The PhD will be co-supervised by @benoitjpons.bsky.social and myself - @cbitoulouse.bsky.social

#PhD #Microbiology #Klebsiella
July 18, 2025 at 2:24 PM
Reposted by Benoit Pons
Had an amazing time at @cbitoulouse.bsky.social! Stimulating discussions, insightful questions, and always a joy to reconnect with old friends and colleagues!
Thanks for the invitation @benoitjpons.bsky.social @olayarendueles.bsky.social
Great talk today @cbitoulouse.bsky.social from @annechevallereau.bsky.social- on the importance of surface receptors in phage adsorption and of intracellular phage defense mechanisms - and the relative importance of each of them in shaping phage host range &productive phage infection 🦠
May 9, 2025 at 4:49 PM
Reposted by Benoit Pons
Great talk today @cbitoulouse.bsky.social from @annechevallereau.bsky.social- on the importance of surface receptors in phage adsorption and of intracellular phage defense mechanisms - and the relative importance of each of them in shaping phage host range &productive phage infection 🦠
May 6, 2025 at 8:37 PM
Reposted by Benoit Pons
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
December 2, 2024 at 12:10 PM
Reposted by Benoit Pons
Looking for a PhD in phage ecology, metagenomics and defence systems? We have a fully funded PhD opportunity to join us at the University of York with great collaborators.

See here for more info:
www.findaphd.com/phds/project...
November 26, 2024 at 4:40 PM
Reposted by Benoit Pons
Lovely day @ CBI with our newest team members already working hard in our brand new lab. Check out the incredible #BlueSky in #Toulouse
#MicroSky
November 15, 2024 at 10:37 AM
Reposted by Benoit Pons
I'm recruiting a Research Technician to work on plasmid transmission and antimicrobial resistance in St Andrews, to start in October. Deadline for applications is 19 June. Please share!
www.vacancies.st-andrews.ac.uk/Vacancies/W/...
Research Assistant - AR2992DM
www.vacancies.st-andrews.ac.uk
May 31, 2024 at 7:37 AM
Reposted by Benoit Pons
Just out in The ISME Journal, a paper from my time in the Westra lab. We find that the extent of phage exposure shapes subsequent resistance dynamics over longer timescales (up to 30 days).

And huge thanks to first authors @bridgetwatson.bsky.social and Loris for mammoth experiments!
CRISPR-Cas in Pseudomonas aeruginosa provides transient population-level immunity against high phage exposures

ISME Journal by Bridget Watson et al
with @ellinoralseth.bsky.social @seanmeaden.bsky.social

academic.oup.com/ismej/advanc...
January 11, 2024 at 11:25 AM