Anne Chevallereau
@annechevallereau.bsky.social
Group leader @CNRS, @MMSB (Lyon, France) studying how viruses interact and evolve with other MGE and with their host #bacterial_immunity #sociovirology #phages #Pseudomonas.
Pinned
The ambivalent effect of spatial structure on the spread of cooperative anti-CRISPR phages https://www.biorxiv.org/content/10.1101/2025.08.06.668856v1
📝New preprint!
We investigated how spatial structure affects cooperation between phages, combining mathematical modelling and experiments.
A short thread 🧶
We investigated how spatial structure affects cooperation between phages, combining mathematical modelling and experiments.
A short thread 🧶
Reposted by Anne Chevallereau
Very happy to see this piece out in @plosbiology.org, on the bacterial immune systems and microbial communities. It was a great team effort with Rafael Custodio, @brockhurstlab.bsky.social , @brownlab.bsky.social, and Edze Westra! 🦠🧫 #phagesky #mevosky
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Bacterial immune systems as causes and consequences of microbiome structure
Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile genetic ele...
journals.plos.org
November 19, 2025 at 6:35 PM
Very happy to see this piece out in @plosbiology.org, on the bacterial immune systems and microbial communities. It was a great team effort with Rafael Custodio, @brockhurstlab.bsky.social , @brownlab.bsky.social, and Edze Westra! 🦠🧫 #phagesky #mevosky
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
🤯
Amazing work..!
Looking forward to digging into the paper.
Amazing work..!
Looking forward to digging into the paper.
🚀New preprint from our lab!
I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡
Continue reading (🧵)
I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡
Continue reading (🧵)
November 20, 2025 at 7:43 PM
🤯
Amazing work..!
Looking forward to digging into the paper.
Amazing work..!
Looking forward to digging into the paper.
Reposted by Anne Chevallereau
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Liverpool on Fin...
PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...
www.findaphd.com
November 18, 2025 at 9:38 AM
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Reposted by Anne Chevallereau
PhD studentship opportunity! Join us at St Andrews to study the factors controlling plasmid transmission in the gut. Competition-funded as part of the EASTBIO DTP, co-supervised with Dr Jaclyn Pearson. Please share & pass on to anyone interested! 🦠🧫 Deadline 15th December👇
www.findaphd.com
November 18, 2025 at 11:41 AM
PhD studentship opportunity! Join us at St Andrews to study the factors controlling plasmid transmission in the gut. Competition-funded as part of the EASTBIO DTP, co-supervised with Dr Jaclyn Pearson. Please share & pass on to anyone interested! 🦠🧫 Deadline 15th December👇
Reposted by Anne Chevallereau
Interested in doing a PhD in phage biology? See below a super cool project on megaphage ecology and evolution available at the University of Jyväskylä (FIN) in Elina Laanto's lab (Project no. 4). Co-supervision provided by yours truly.
🚀 PhD opportunity
The Dept of Biological and Environmental Science, University of Jyväskylä, is recruiting 1–4 new PhD candidates.
One of the positions is potentially in my lab, focusing on megaphages and their hosts.
Details and apply here 👇
bit.ly/48eqYNB
#phage
The Dept of Biological and Environmental Science, University of Jyväskylä, is recruiting 1–4 new PhD candidates.
One of the positions is potentially in my lab, focusing on megaphages and their hosts.
Details and apply here 👇
bit.ly/48eqYNB
#phage
Doctoral Researcher positions, Biological and Environmental Sciences
The Department of Biological and Environmental Sciences is seeking applicants for 1–4 fully funded doctoral researcher positions. The positions will begin on August 1, 2026, or as agreed, for a maximu...
ats.talentadore.com
November 14, 2025 at 9:47 AM
Interested in doing a PhD in phage biology? See below a super cool project on megaphage ecology and evolution available at the University of Jyväskylä (FIN) in Elina Laanto's lab (Project no. 4). Co-supervision provided by yours truly.
JOB OFFER #PhageSky
We have a postdoc position opening in my group to investigate phage-MGE interactions !
We're based in the very nice city of Lyon, France @mmsb-lyon.bsky.social
Contact me for more info !
>> Apply on the CNRS webpage emploi.cnrs.fr/Offres/CDD/U...
We have a postdoc position opening in my group to investigate phage-MGE interactions !
We're based in the very nice city of Lyon, France @mmsb-lyon.bsky.social
Contact me for more info !
>> Apply on the CNRS webpage emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Offre d'emploi - Postdoctoral researcher Microbiology (M/F)
emploi.cnrs.fr
October 22, 2025 at 9:35 AM
JOB OFFER #PhageSky
We have a postdoc position opening in my group to investigate phage-MGE interactions !
We're based in the very nice city of Lyon, France @mmsb-lyon.bsky.social
Contact me for more info !
>> Apply on the CNRS webpage emploi.cnrs.fr/Offres/CDD/U...
We have a postdoc position opening in my group to investigate phage-MGE interactions !
We're based in the very nice city of Lyon, France @mmsb-lyon.bsky.social
Contact me for more info !
>> Apply on the CNRS webpage emploi.cnrs.fr/Offres/CDD/U...
Reposted by Anne Chevallereau
New pre-print www.biorxiv.org/content/10.1...
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky
Trade-offs between phage resistance and conjugative ability shape the ecological and evolutionary response of a multidrug resistance plasmid to plasmid-dependent phage
Phage therapy is a promising alternative to antibiotics to treat multidrug resistant infections. Plasmid dependent phages (PDPs) are particularly attractive as therapeutics because they can both kill ...
www.biorxiv.org
October 9, 2025 at 10:07 AM
New pre-print www.biorxiv.org/content/10.1...
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky
Reposted by Anne Chevallereau
#ResultatScientifique 🔎| Le complexe CST protège l’ADN en réparant les cassures même après dégradation partielle, limitant ainsi les mutations dangereuses 🧬
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
Le complexe CST, un acteur inattendu de la réparation de l’ADN
Réparer l’ADN endommagé est un processus essentiel à l’intégrité du génome, qui peut être dérégulé dans les cancers.
www.insb.cnrs.fr
October 7, 2025 at 2:36 PM
#ResultatScientifique 🔎| Le complexe CST protège l’ADN en réparant les cassures même après dégradation partielle, limitant ainsi les mutations dangereuses 🧬
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
Reposted by Anne Chevallereau
DYK most P. aeruginosa carry filamentous phage(s) that don't need to kill the cell to reproduce?
We 👉🏻@nanamikubota.bsky.social show that these Pf phages can go ROGUE.
"Filamentous cheater phages drive bacterial and phage populations to lower fitness"
🔗 authors.elsevier.com/c/1lt5I3QW8S...
We 👉🏻@nanamikubota.bsky.social show that these Pf phages can go ROGUE.
"Filamentous cheater phages drive bacterial and phage populations to lower fitness"
🔗 authors.elsevier.com/c/1lt5I3QW8S...
October 2, 2025 at 3:55 PM
DYK most P. aeruginosa carry filamentous phage(s) that don't need to kill the cell to reproduce?
We 👉🏻@nanamikubota.bsky.social show that these Pf phages can go ROGUE.
"Filamentous cheater phages drive bacterial and phage populations to lower fitness"
🔗 authors.elsevier.com/c/1lt5I3QW8S...
We 👉🏻@nanamikubota.bsky.social show that these Pf phages can go ROGUE.
"Filamentous cheater phages drive bacterial and phage populations to lower fitness"
🔗 authors.elsevier.com/c/1lt5I3QW8S...
Reposted by Anne Chevallereau
#Évènement🎟️|
Lancement de la 3️⃣ème saison des #ÉchappéesInattendues du @cnrs.fr avec la conférence immersive de Jean-Michel Jault, biologiste au @mmsb-lyon.bsky.social sur l’antibiorésistance 🧫 des bactéries 🦠 pour la #FDS2025
📅 11 octobre
🕢 à 17h30
✔️ sur inscription : bit.ly/confmmsb
#FDSAURA
Lancement de la 3️⃣ème saison des #ÉchappéesInattendues du @cnrs.fr avec la conférence immersive de Jean-Michel Jault, biologiste au @mmsb-lyon.bsky.social sur l’antibiorésistance 🧫 des bactéries 🦠 pour la #FDS2025
📅 11 octobre
🕢 à 17h30
✔️ sur inscription : bit.ly/confmmsb
#FDSAURA
October 1, 2025 at 9:23 AM
#Évènement🎟️|
Lancement de la 3️⃣ème saison des #ÉchappéesInattendues du @cnrs.fr avec la conférence immersive de Jean-Michel Jault, biologiste au @mmsb-lyon.bsky.social sur l’antibiorésistance 🧫 des bactéries 🦠 pour la #FDS2025
📅 11 octobre
🕢 à 17h30
✔️ sur inscription : bit.ly/confmmsb
#FDSAURA
Lancement de la 3️⃣ème saison des #ÉchappéesInattendues du @cnrs.fr avec la conférence immersive de Jean-Michel Jault, biologiste au @mmsb-lyon.bsky.social sur l’antibiorésistance 🧫 des bactéries 🦠 pour la #FDS2025
📅 11 octobre
🕢 à 17h30
✔️ sur inscription : bit.ly/confmmsb
#FDSAURA
Reposted by Anne Chevallereau
You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range.
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
Phages with a broad host range are common across ecosystems - Nature Microbiology
Proximity-ligation-based sequencing from 111 samples and 5 environments reveals that a substantial proportion of phages infect multiple species.
www.nature.com
September 19, 2025 at 9:32 AM
You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range.
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social
www.nature.com/articles/s41...
Reposted by Anne Chevallereau
Exclusion systems, far from slowing down plasmid spread, are in fact essential to preserve host cell viability and thereby ensure the successful dissemination of conjugative plasmids and antibiotic resistance genes.
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
Exclusion systems preserve host cell homeostasis and fitness, ensuring successful dissemination of conjugative plasmids and associated resistance genes
Abstract. Plasmid conjugation is a major driver of antibiotic resistance dissemination in bacteria. In addition to genes required for transfer and maintena
academic.oup.com
September 17, 2025 at 10:17 AM
Exclusion systems, far from slowing down plasmid spread, are in fact essential to preserve host cell viability and thereby ensure the successful dissemination of conjugative plasmids and antibiotic resistance genes.
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
Reposted by Anne Chevallereau
YprA family helicases provide the missing link between diverse prokaryotic immune systems https://www.biorxiv.org/content/10.1101/2025.09.15.676423v1
September 16, 2025 at 6:17 AM
YprA family helicases provide the missing link between diverse prokaryotic immune systems https://www.biorxiv.org/content/10.1101/2025.09.15.676423v1
Reposted by Anne Chevallereau
We're looking for a technician at Institut Pasteur for experimental work on satellite-phage-bacteria interactions, working directly with @jmouradesousa.bsky.social and myself in the lab of @epcrocha.bsky.social ! ANR funded.
Link to the job emploi.pasteur.fr/offre-de-emp...
Thx for sharing!
Link to the job emploi.pasteur.fr/offre-de-emp...
Thx for sharing!
INSTITUT PASTEUR - Technicien de recherche Microbiologie H/F
emploi.pasteur.fr
September 12, 2025 at 2:42 PM
We're looking for a technician at Institut Pasteur for experimental work on satellite-phage-bacteria interactions, working directly with @jmouradesousa.bsky.social and myself in the lab of @epcrocha.bsky.social ! ANR funded.
Link to the job emploi.pasteur.fr/offre-de-emp...
Thx for sharing!
Link to the job emploi.pasteur.fr/offre-de-emp...
Thx for sharing!
Reposted by Anne Chevallereau
For anyone who has used pling for comparing plasmids using rearrangement distances ("how many structural events apart are these plasmids"), here's how to tweak parameters, and integrate it with typing info, and the host phylogeny
www.biorxiv.org/content/10.1...
github.com/iqbal-lab-or...
www.biorxiv.org/content/10.1...
github.com/iqbal-lab-or...
Clustering of plasmid genomes for genomic epidemiology by using rearrangement distances, with pling
Integration of plasmids into genomic epidemiology is challenging, because there are no clearly defined evolving-units (equivalent to species), and because plasmids appear to evolve as much by structur...
www.biorxiv.org
September 7, 2025 at 2:56 PM
For anyone who has used pling for comparing plasmids using rearrangement distances ("how many structural events apart are these plasmids"), here's how to tweak parameters, and integrate it with typing info, and the host phylogeny
www.biorxiv.org/content/10.1...
github.com/iqbal-lab-or...
www.biorxiv.org/content/10.1...
github.com/iqbal-lab-or...
Reposted by Anne Chevallereau
At last ! A tool specifically for phage-plasmid hunters. Check tyPPing by @karinailchenko.bsky.social and @eugenpfeifer.bsky.social
🚨 New preprint! 🧬
𝐏𝐡𝐚𝐠𝐞-𝐩𝐥𝐚𝐬𝐦𝐢𝐝𝐬 (𝐏-𝐏𝐬) are fascinating elements: both 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐞 𝐩𝐡𝐚𝐠𝐞𝐬 and 𝐩𝐥𝐚𝐬𝐦𝐢𝐝𝐬 ➡️ tricky to detect.
We present 𝐭𝐲𝐏𝐏𝐢𝐧𝐠 — the first 𝐢𝐝𝐞𝐧𝐭𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐜𝐥𝐚𝐬𝐬𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐭𝐨𝐨𝐥 🛠️designed specifically for P-Ps:
✅ Accurate
✅ Sensitive
✅ Easy to use
📖 www.biorxiv.org/content/10.1...
𝐏𝐡𝐚𝐠𝐞-𝐩𝐥𝐚𝐬𝐦𝐢𝐝𝐬 (𝐏-𝐏𝐬) are fascinating elements: both 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐞 𝐩𝐡𝐚𝐠𝐞𝐬 and 𝐩𝐥𝐚𝐬𝐦𝐢𝐝𝐬 ➡️ tricky to detect.
We present 𝐭𝐲𝐏𝐏𝐢𝐧𝐠 — the first 𝐢𝐝𝐞𝐧𝐭𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐜𝐥𝐚𝐬𝐬𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐭𝐨𝐨𝐥 🛠️designed specifically for P-Ps:
✅ Accurate
✅ Sensitive
✅ Easy to use
📖 www.biorxiv.org/content/10.1...
Efficient detection and typing of phage-plasmids
Phage-plasmids are temperate phages that replicate as plasmids during lysogeny. Despite their high diversity, they carry genes similar to phages and plasmids. This leads to gene exchanges, and to the ...
www.biorxiv.org
September 3, 2025 at 2:00 PM
At last ! A tool specifically for phage-plasmid hunters. Check tyPPing by @karinailchenko.bsky.social and @eugenpfeifer.bsky.social
Reposted by Anne Chevallereau
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.
www.science.org
September 6, 2025 at 9:35 AM
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
Reposted by Anne Chevallereau
Delighted to share our recently published work!
Ever wondered how Klebsiella (and others) deals with capsule production’s costs ?
The paper: journals.asm.org/doi/10.1128/...
Thread👇
Ever wondered how Klebsiella (and others) deals with capsule production’s costs ?
The paper: journals.asm.org/doi/10.1128/...
Thread👇
Phenotypic heterogeneity of capsule production across opportunistic pathogens | mBio
The polysaccharidic capsule is present in ~50% of species across the bacterial phylogeny, including all ESKAPE microorganisms, the six most significant multidrug-resistant (MDR) nosocomial pathogens. It is also an important virulence factor and a major ...
journals.asm.org
September 5, 2025 at 1:49 PM
Delighted to share our recently published work!
Ever wondered how Klebsiella (and others) deals with capsule production’s costs ?
The paper: journals.asm.org/doi/10.1128/...
Thread👇
Ever wondered how Klebsiella (and others) deals with capsule production’s costs ?
The paper: journals.asm.org/doi/10.1128/...
Thread👇
Happy to see our paper out!
Functional assessment of anti-phage defence systems in their native clinical E. coli host
royalsocietypublishing.org/doi/10.1098/...
Thread in previous post 👇
Functional assessment of anti-phage defence systems in their native clinical E. coli host
royalsocietypublishing.org/doi/10.1098/...
Thread in previous post 👇
September 5, 2025 at 10:44 AM
Happy to see our paper out!
Functional assessment of anti-phage defence systems in their native clinical E. coli host
royalsocietypublishing.org/doi/10.1098/...
Thread in previous post 👇
Functional assessment of anti-phage defence systems in their native clinical E. coli host
royalsocietypublishing.org/doi/10.1098/...
Thread in previous post 👇
Reposted by Anne Chevallereau
How do bacteria choose what type of defences to use against phages? We explored that question in the last paper I worked on as a postdoc at the Uni of Exeter @uniofexeteresi.bsky.social with Stineke van Houte, Stefano Pagliara and Edze Westra (not on Bluesky)
doi.org/10.1098/rstb...
doi.org/10.1098/rstb...
Phage provoke growth delays and SOS response induction despite CRISPR-Cas protection | Philosophical Transactions of the Royal Society B: Biological Sciences
Bacteria evolve resistance against their phage foes with a wide range of resistance
strategies whose costs and benefits depend on the level of protection they confer
and on the costs for maintainance....
doi.org
September 4, 2025 at 4:02 PM
How do bacteria choose what type of defences to use against phages? We explored that question in the last paper I worked on as a postdoc at the Uni of Exeter @uniofexeteresi.bsky.social with Stineke van Houte, Stefano Pagliara and Edze Westra (not on Bluesky)
doi.org/10.1098/rstb...
doi.org/10.1098/rstb...
🎉🧪 The MEEP lab @mmsb.cnrs.fr celebrates its first anniversary!
A year of experiments, caffeine-fueled late nights, and nerdy excitement. 🚀🔬
I'm very grateful to the team of amazing #WomenInScience who joined this incredible journey
@josie-e.bsky.social
Clarisse Plantady and Elodie Kenck.
A year of experiments, caffeine-fueled late nights, and nerdy excitement. 🚀🔬
I'm very grateful to the team of amazing #WomenInScience who joined this incredible journey
@josie-e.bsky.social
Clarisse Plantady and Elodie Kenck.
September 4, 2025 at 1:04 PM
🎉🧪 The MEEP lab @mmsb.cnrs.fr celebrates its first anniversary!
A year of experiments, caffeine-fueled late nights, and nerdy excitement. 🚀🔬
I'm very grateful to the team of amazing #WomenInScience who joined this incredible journey
@josie-e.bsky.social
Clarisse Plantady and Elodie Kenck.
A year of experiments, caffeine-fueled late nights, and nerdy excitement. 🚀🔬
I'm very grateful to the team of amazing #WomenInScience who joined this incredible journey
@josie-e.bsky.social
Clarisse Plantady and Elodie Kenck.
Reposted by Anne Chevallereau
Can CRISPR-Cas systems target any phage? Yes, no, it depends? What does it depend on? The second paper from my PhD came out today in a special issue of Phil Trans B on the ecology and evolution of bacterial immune systems
doi.org/10.1098/rstb...
doi.org/10.1098/rstb...
Phage susceptibility to a minimal, modular synthetic CRISPR-Cas system in Pseudomonas aeruginosa is nutrient dependent | Philosophical Transactions of the Royal Society B: Biological Sciences
CRISPR-Cas systems can provide adaptive, heritable immunity to their prokaryotic hosts
against invading genetic material such as phages. It is clear that the importance
of acquiring CRISPR-Cas immunit...
doi.org
September 4, 2025 at 11:32 AM
Can CRISPR-Cas systems target any phage? Yes, no, it depends? What does it depend on? The second paper from my PhD came out today in a special issue of Phil Trans B on the ecology and evolution of bacterial immune systems
doi.org/10.1098/rstb...
doi.org/10.1098/rstb...
Reposted by Anne Chevallereau
#ResultatScientifique🔎| Des scientifiques ont révélé comment le plasmide pOXA-48 rend les bactéries ultra-résistantes aux antibiotiques 🦠
🤝 @cnrs.fr @mmsb-lyon.bsky.social @cnrs-rhoneauvergne.bsky.social
✍️ @sbigot.bsky.social
📕 @natcomms.nature.com | buff.ly/u3Cy4Db
🤝 @cnrs.fr @mmsb-lyon.bsky.social @cnrs-rhoneauvergne.bsky.social
✍️ @sbigot.bsky.social
📕 @natcomms.nature.com | buff.ly/u3Cy4Db
September 4, 2025 at 8:30 AM
#ResultatScientifique🔎| Des scientifiques ont révélé comment le plasmide pOXA-48 rend les bactéries ultra-résistantes aux antibiotiques 🦠
🤝 @cnrs.fr @mmsb-lyon.bsky.social @cnrs-rhoneauvergne.bsky.social
✍️ @sbigot.bsky.social
📕 @natcomms.nature.com | buff.ly/u3Cy4Db
🤝 @cnrs.fr @mmsb-lyon.bsky.social @cnrs-rhoneauvergne.bsky.social
✍️ @sbigot.bsky.social
📕 @natcomms.nature.com | buff.ly/u3Cy4Db
Reposted by Anne Chevallereau
Plasmids can be lost from a bacterial community even under positive environmental selection: doi.org/10.1101/2025...
Species interactions determine plasmid persistence in a 3-member bacterial community
Microbial communities are shaped by complex forces, including interspecies interactions and the effects of mobile genetic elements such as plasmids. How these forces interact to affect community respo...
doi.org
September 3, 2025 at 7:21 PM
Plasmids can be lost from a bacterial community even under positive environmental selection: doi.org/10.1101/2025...
Reposted by Anne Chevallereau
Cool preprint by Mathieu Berge @polardlab.bsky.social showing that the Spr1630 toxin (RipA) toxin targets the replication sliding-clamp (DnaN) and that this induces competence in Streptococcus pneumoniae. www.biorxiv.org/content/10.1...
A toxin/antitoxin system targeting the replication sliding-clamp induces competence in Streptococcus pneumoniae.
Streptococcus pneumoniae is a pathogenic bacterium capable of entering a cellular differentiation state, called competence, which enables it to acquire new genetic functions by natural transformation,...
www.biorxiv.org
September 3, 2025 at 7:01 AM
Cool preprint by Mathieu Berge @polardlab.bsky.social showing that the Spr1630 toxin (RipA) toxin targets the replication sliding-clamp (DnaN) and that this induces competence in Streptococcus pneumoniae. www.biorxiv.org/content/10.1...