Beatriz Urda
beatrizurda.bsky.social
Beatriz Urda
@beatrizurda.bsky.social

PhDing at Barcelona Supercomputing Center | Exploring disease co-occurrences through omics, bioinformatics & HPC — with an eye on AI bias, and occasionally covered in clay.
Pinned
1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min

From Alfonso Valencia’s lab and a very stubborn PhD student (me).
Reposted by Beatriz Urda
Entrevista de Artur Olesch a @alfonsovalencia.bsky.social en #DigitalHealth sobre el incierto futuro de la #IA. Muy recomendable
aboutdigitalhealth.com/2025/11/06/a...
AI’s uncertain future
“If this is the final stage of AI, we’re in trouble.” — Alfonso Valencia on the risks and promise of generative models. Continue Reading
aboutdigitalhealth.com
November 7, 2025 at 8:40 AM
Reposted by Beatriz Urda
📄Ver publicación del primer estudio de comorbilidades en PNAS: pnas.org/doi/10.1073/...

🔘Plataforma interactiva de red de conexiones entre enfermedades: disease-perception.bsc.es/rgenexcom/

@beatrizurda.bsky.social @alfonsovalencia.bsky.social

#DíaMundialCáncerMama #19Octubre
October 17, 2025 at 9:02 AM
Reposted by Beatriz Urda
⭕ El BSC explora las conexiones entre enfermedades como el #cáncerdemama y busca distinguir qué parte de estas relaciones se explica por la #genética o por 𝗳𝗮𝗰𝘁𝗼𝗿𝗲𝘀 𝗮𝗺𝗯𝗶𝗲𝗻𝘁𝗮𝗹𝗲𝘀 o modificables.

🔘Casi la mitad de estas conexiones tiene un origen que 𝘃𝗮➕𝗮𝗹𝗹á 𝗱𝗲𝗹 𝗔𝗗𝗡 y son potencialmente modificables.
October 17, 2025 at 9:02 AM
Reposted by Beatriz Urda
Some diseases show up together. Others rarely appear in the same person

This study looked into whether gene activity (from RNA data) can help explain why

The answer: yes - more than we thought

Relevant as we are testing RNA in LC & ME/CFS patients @amaticahealth

Breakdown:
September 10, 2025 at 1:49 PM
Reposted by Beatriz Urda
💻🧬'Los vínculos secretos que existen entre enfermedades.
El estudio del BSC representa el mayor esfuerzo hasta la fecha para explicar científicamente las asociaciones clínicas entre enfermedades'

🗞En @innovaspain.bsky.social
www.bsc.es/4kD

@alfonsovalencia.bsky.social @beatrizurda.bsky.social
September 9, 2025 at 7:58 AM
Excited to see our PNAS paper highlighted on Kudos, with an accessible take on the findings.

Disease links are not random—they can be predicted from the expression of our genes.
www.growkudos.com/publications...

@pnas.org @alfonsovalencia.bsky.social
📄 doi.org/10.1073/pnas...
Molecular map reveals hidden disease connections
Diseases rarely come alone. Many people experience a chain of diagnoses across their lives—for example, smoking-related lung cancer, asthma followed by Parkinson’s disease, or depression alongside lup...
www.growkudos.com
September 8, 2025 at 4:30 PM
Reposted by Beatriz Urda
🧬 New research in PNAS shows how gene expression patterns reveal why some diseases occur together while others don’t.

Scientists uncovered hidden links — with immune pathways playing a major role.

#GeneExpression #Comorbidity #PrecisionHealth

🔗 www.news-medical.net/news/2025090...
Gene expression maps explain why diseases often occur together
This study reveals how gene expression patterns uncover molecular pathways linking comorbidities, enhancing treatment strategies for overlapping diseases.
www.news-medical.net
September 5, 2025 at 10:10 AM
Reposted by Beatriz Urda
Great #networkmedicine work by @alfonsovalencia.bsky.social's team on deriving comorbidity networks from RNA-seq data to study complex disease relationships. Thy show that molecular mechanisms are behind many of the known comorbidities (often via immune response).
doi.org/10.1073/pnas...
Patient stratification reveals the molecular basis of disease co-occurrences | PNAS
Epidemiological evidence shows that some diseases tend to co-occur; more exactly, certain groups of patients with a given disease are at a higher r...
doi.org
September 3, 2025 at 10:33 PM
Reposted by Beatriz Urda
No le habéis hecho mucho caso a esto, pero es muy, muy bonito. Y parece revolucionario. Seguro que volveremos a oír hablar de esto.
In the end, comorbidities aren’t random,
they can be predicted from the expression of our genes 🧬

And this is just the beginning.
Stay tuned for what comes next 👀🚀
September 4, 2025 at 7:35 AM
Reposted by Beatriz Urda
Totally! In our case it wasn’t even about sample size, but a basic textbook statistical concept 🤖. We even increased the sample size to show the results still held under the reviewer’s definition—and still, they wouldn’t budge.
September 3, 2025 at 4:17 PM
Reposted by Beatriz Urda
Un nuevo método computacional, creado en el @bsc-cns.bsky.social y basado en datos de más de 4 000 pacientes y 45 patologías, identifica conexiones clínicas conocidas y sugiere asociaciones inéditas con posibles aplicaciones en el diagnóstico y los tratamientos.

www.agenciasinc.es/Noticias/El-...
El BSC diseña un mapa molecular que descubre vínculos ocultos entre enfermedades
Un nuevo método computacional basado en datos de más de 4 000 pacientes y 45 patologías identifica conexiones clínicas conocidas y sugiere asociaciones inéditas con posibles aplicaciones en el diagnóstico y los tratamientos.
www.agenciasinc.es
September 2, 2025 at 9:28 AM
Reposted by Beatriz Urda
She explains part of the fight over 2 years with an absurd referee (can happen) and an incompetent profesional editor unable to understand even basic statistics - or worse unable to take a decision by him/her self.

But never mind: Beatriz won and the paper is now published in a better journal.
1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min

From Alfonso Valencia’s lab and a very stubborn PhD student (me).
September 2, 2025 at 7:00 PM
Reposted by Beatriz Urda
Very happy to get it out.

For scientific & personal reasons this one is special.
Beatriz has done more work and endured the most difficult - and absurd - publications battles I can remember.
Thanks to PNAS for being "normal" and congratulations to Beatriz.

(Beatriz: next one will be easier!)
🚨 New in PNAS!
🧬 64% of disease co-occurrences can be explained by transcriptomic similarities.

Comorbidities aren’t random—they have a molecular basis.

Here’s how we found it 👇 (1/n)

🔗 doi.org/10.1073/pnas.2421060122

@alfonsovalencia.bsky.social
September 2, 2025 at 6:55 PM
1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min

From Alfonso Valencia’s lab and a very stubborn PhD student (me).
September 2, 2025 at 6:37 PM
🚨 New in PNAS!
🧬 64% of disease co-occurrences can be explained by transcriptomic similarities.

Comorbidities aren’t random—they have a molecular basis.

Here’s how we found it 👇 (1/n)

🔗 doi.org/10.1073/pnas.2421060122

@alfonsovalencia.bsky.social
September 2, 2025 at 11:42 AM
Reposted by Beatriz Urda
🧬💻El BSC crea un método computacional que revela conexiones hasta ahora ocultas entre enfermedades.

ℹMás info: www.bsc.es/4ke

💻 Acceder a la plataforma interactiva: disease-perception.bsc.es/rgenexcom/

📄 Publicado en @pnas.org

#supercomputación #IA #enfermedades
September 1, 2025 at 10:44 AM
Reposted by Beatriz Urda
👏🏆 Congrats to our #NetBio2025 prize winners:
- Best Talk: Beatriz Urda-García
- Best Poster Method: Arne Wehling
- Best Poster Application: Sebastian Urquiza-Zurich
- Best Poster Tool: Estefania Torrejon

Thanks to all the (poster) presenters!!! It's amazing to have you in our community!!
July 24, 2025 at 5:03 PM
Reposted by Beatriz Urda
🎤 Next talk at #NetBio:
@beatrizurda.bsky.social: Disentangling the genetic and non-genetic origin of disease co-occurrences

#ISMBECCB2025 #NetworkBiology
July 22, 2025 at 2:49 PM
Reposted by Beatriz Urda
🌐BSC is a proud partner of EU CIP project, that aims to create a #CancerInfoPortal to improve health literacy, empower patients, and reduce inequalities in access to cancer care information across Europe.
👋 Hello

🏡 We are the #EU-CIP project. We are building the #CancerInfoPortal - home for reliable and easy to understand information cancer patients and their families and carers in Europe.

🤝 We just kicked-off the project with partners from 18 European countries. Let's introduce you to EU-CiP. 1/7
June 27, 2025 at 8:53 AM
I’m really curious: what else will we need to act?
Enter your location and be moved. showyourstripes.info/c/europe/spa...
Show Your Stripes
Visualising how the climate has changed for every country across the globe
showyourstripes.info
June 21, 2025 at 12:25 PM
Reposted by Beatriz Urda
🚬The molecular impact of cigarette smoking resembles aging across tissues

⭕This is the 1st comprehensive, multi-tissue analysis to show that smoking doesn’t just harm specific organs like the lungs 🫁

📄By BSC & Universidade do Porto researchers, published in Genome Medicine: bsc.es/Zt2
June 5, 2025 at 8:11 AM
Reposted by Beatriz Urda
New research alert 📝❗❗❗

In our latest pre-print, 2nd of my PhD, we performed a Systematic Literature Review on the use of Deep Representational Learning (DRL), especially the Variational Autoencoder (VAE), in cancer progression research.

This thread explains our main findings.

(1 minute read)
June 12, 2025 at 9:43 AM
Reposted by Beatriz Urda
The first year of school is when a maths gap between boys & girls emerges, according to a 4-year longitudinal assessment of language & mathematical performance of all French first and second graders (2,653,082 children!)

We now know when to focus interventions
🧪
www.nature.com/articles/s41...
Rapid emergence of a maths gender gap in first grade - Nature
Boys and girls exhibit very similar maths scores upon school entry, but a gender gap in favour of boys becomes highly significant after 4 months of schooling, which increases with years of schooling,&...
www.nature.com
June 16, 2025 at 6:05 AM
Reposted by Beatriz Urda
New Insights into Medulloblastoma! 🧠

I am very happy to announce the first paper in my Ph.D. thesis journey:

Exploring the Boundaries of Medulloblastoma Subgroups with synthetic Data Generation -> www.biorxiv.org/content/10.1...

Let’s dive in into our findings with this thread! 🧵⤵️
Exploring the Boundaries of Medulloblastoma Subgroups with Synthetic Data Generation
Medulloblastoma is a childhood brain tumor traditionally classified into four molecular subgroups. Recent evidence suggests that Groups 3 and 4 represent a biological continuum rather than distinct en...
www.biorxiv.org
January 13, 2025 at 3:07 PM