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bastianengel.bsky.social
@bastianengel.bsky.social
120 followers 240 following 15 posts
MD, GI & Hepatology, Hannover Medical School. Interested in Liver Transplantation and Autoimmune Liver Disease.
Posts Replies Media Videos
bastianengel.bsky.social
🔥 non-medical
🌎 planetary health is critical

Check out this video by naturalists about sustainable tourism and ocean protection on the Azores.

Scientist-led, EU-funded 🇪🇺

Happy to have joined this year. Check it out.
support them if you visit the Azores.

www.euronews.com/green/2025/0...
How Atlantic islands are proving tourism can help the ocean
From underwater archaeology to whale-watching tours led by actual scientists, Europe’s Atlantic islands demonstrate how tourism can protect rather than destroy natural and cultural heritage of the oce...
www.euronews.com
July 30, 2025 at 6:14 AM
bastianengel.bsky.social
🔥 Looking for automated segmentation of liver histopathology? Don‘t look further.

Hotspot Model got you covered.

Happy to have contributed.

Great work @aleger87.bsky.social and team!

rdcu.be/ew7qh
Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model
npj Digital Medicine - Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model
rdcu.be
July 22, 2025 at 6:04 AM
bastianengel.bsky.social
🔥 Publication alert from us!

🧬 Distinct molecular profiles of AMR and TCMR after #liver #transplant
📈 AMR associates w/ high rate of graft #cirrhosis
🧪 IFN mediates TCMR, TNF mediates AMR as in other SOT

doi.org/10.1016/j.jh...

#openaccess @jhepatology.bsky.social
#liversky @easlnews.bsky.social
Redirecting
doi.org
July 17, 2025 at 2:06 PM
bastianengel.bsky.social
🔥 Publication alert from our group!

🧬 Distinct molecular profiles of AMR and TCMR after #liver #transplant
📈 AMR associates w/ high rates of graft #cirrhosis
🧪 IFN mediates TCMR and TNF mediates AMR as in other solid organs

#openaccess @jhepatology.bsky.social
#liversky @easlnews.bsky.social
July 15, 2025 at 5:03 PM
Reposted
janclusmann.bsky.social
Thank you for sharing! It was a pleasure working on this, together with @twittlabs.bsky.social , @jnkt.bsky.social and many others...
ai.nejm.org NEJM AI @ai.nejm.org · Jun 30
Case Study by J. Clusmann et al.: Incidental Prompt Injections on Vision–Language Models in Real-Life Histopathology nejm.ai/4mrSoEW

@janclusmann.bsky.social #AI #MedSky #DigitalHealth
Figure 1. Experimental Outline to Estimate the Impact and the Clinical Representation of Labeled Pathology Slides. Figure 2. Incorrect Labels on Whole-Slide Images Reduce the Accuracy of Vision–Language Models Regardless of Task. Figure 3. Misleading Watermarks Lead to a Loss in Accuracy of Tissue-of-Origin Prediction.
June 30, 2025 at 1:49 PM
bastianengel.bsky.social
Whom to treat in #AIH #cirrhosis with decompensation?

💊 Steroids if:
🧠 encephalopathy equal or less than grade 2
📈 MELD-Na 28 or below

🚒If patients with AIH do not meet this criteria #transplant might be the better option.

#liversky @easlnews.bsky.social

authors.elsevier.com/c/1l6Pu5UiFS...
authors.elsevier.com
May 19, 2025 at 7:28 AM
Reposted
jhepatology.bsky.social
🆕CPG in press❕

EASL Clinical Practice Guidelines on extrahepatic abdominal surgery in patients with cirrhosis and advanced chronic liver disease

Find it here👉https://bit.ly/3GM9EEB

#LiverSky
@easlnews.bsky.social
May 10, 2025 at 6:05 AM
Reposted
robbrierley.bsky.social
New @thelancet.bsky.social - Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial

www.thelancet.com/journals/lan...

#Liversky #Oncsky #Medsky #EASL2025
Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial
Nivolumab plus ipilimumab showed a significant overall survival benefit versus lenvatinib or sorafenib and manageable safety in patients with previously untreated unresectable hepatocellular carcinoma...
www.thelancet.com
May 8, 2025 at 1:01 PM
Reposted
anderssonlab.bsky.social
Can’t wait for #EASL2025! @easlnews.bsky.social

Join Colm O’Rourke and me, on Friday for a session we’ve designed and are thrilled to chair:
“Do’s and Don’ts in Liver Transcriptomics”
Arnold Room | 3–4PM

Come for insights, tips & tricks from Neil Henderson, Johan Ankarklev, & Simon Cockell!
May 7, 2025 at 10:15 AM
Reposted
jhepatology.bsky.social
🆕CPG❕

EASL Clinical Practice Guidelines on TIPS

✅Addresses all aspects of #TIPS in patients with #cirrhosis

Full text here: bit.ly/4hZuMUK

#LiverSky
@easlnews.bsky.social
April 3, 2025 at 7:56 AM
Reposted
thervacb-eu.bsky.social
🤔How is #hepD treated? Why is this relevant for #hepB patients? 🇩🇪🗺️
🎞️Watch insights from #internists 🥼#HelenieKefalakes
#LisaSandmann in our fresh release youtu.be/d7dV2G6tMXA
#hepatitisawareness📺with experts answering key #HBV #HDV questions
#MHH #B_Aware #D-SOLVE #LiverHealth #LiverSky #HepSky
How is hepatitis D treated?
YouTube video by TherVacB - Awareness & Insights on Hepatitis B
youtu.be
April 2, 2025 at 8:52 AM
Reposted
zcarrero-katherlab.bsky.social
✮ Kather Lab is hiring PostDocs & Software Engineers!

☞ Strong Python & PyTorch skills, GitHub experience, and interest in LLMs & computational pathology required. 



Apply here╰( ͡° ͜ʖ ͡° )つ──☆*・ﾟ: bit.ly/42nY62u
March 31, 2025 at 2:41 PM
Reposted
jnkt.bsky.social
Happy to share our latest paper in @ai.nejm.org, led by Isabella Wiest: "Deidentifying Medical Documents with Local, Privacy-Preserving Large Language Models: The LLM-Anonymizer" ai.nejm.org/doi/full/10....
You can use our open source tool with local LLMs to robustly de-identify medical documents.
March 27, 2025 at 6:32 PM
Reposted
ebtapper.bsky.social
Spicy!

Adding lasix to the management of hepatorenal syndrome might be ok if you bump the MAP with pressors

@juancarlosqvelez.bsky.social

doi.org/10.1016/j.ek...
#nephsky #liversky
March 4, 2025 at 12:08 AM
bastianengel.bsky.social
Find the latest evidence on #autoimmune #liver diseases (in German, but #AI will help to translate) in which we summarize the latest evidence, finally on the highest level achievable for guidelines.

This highlights the progress in the #AILD field in the last years.

www.dgvs.de/leitlinien/l...
Seltene Lebererkrankungen (LeiSe LebEr) - DGVS - Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten
www.dgvs.de
February 21, 2025 at 10:36 AM
bastianengel.bsky.social
Fresh from #Hepatology, cross-sectional multicenter study on Quality of Life in #AIH.

👍 882 patients, 178 controls across Europe #ERN
👎 QoL impaired mainly by physical complaints
📈 QoL correlated w/ depression/anxiety
💊 remission associated w/ improved symptoms

doi.org/10.1097/HEP.0000000000001271
Health-related quality of life is impaired in people with... : Hepatology
ted outcome measures. Methods: Adult AIH patients diagnosed at 12 European centers were enrolled in this prospective, cross-sectional study from July 2020-June 2023. HRQoL was assessed using the Ph...
doi.org
February 20, 2025 at 6:47 AM
Reposted
easlnews.bsky.social
In today's #readoftheweek📚 learn about the ALNE model and how it generates quantitative and accurate differential diagnosis between cases with AIH or PBC.

Read here this JHEP Reports article: www.jhep-reports.eu/article/S258...

@jhepatology.bsky.social #LiverSky
February 19, 2025 at 3:38 PM
bastianengel.bsky.social
Happy to have contributed to this project led by @aleger87.bsky.social

🤖 ML-based detection of AIH and PBC from H&E stained slides
💥 solid performance with heterogenous staining/scanning
😳 no annotation needed

More to come and looking forward to it! @jnkt.bsky.social #liversky
easlnews.bsky.social EASL @easlnews.bsky.social · Feb 19
In today's #readoftheweek📚 learn about the ALNE model and how it generates quantitative and accurate differential diagnosis between cases with AIH or PBC.

Read here this JHEP Reports article: www.jhep-reports.eu/article/S258...

@jhepatology.bsky.social #LiverSky
February 20, 2025 at 6:06 AM
bastianengel.bsky.social
🔥 off the press.
Multicenter study using proteomic signatures to identify biomarker candidates in acute liver failure led by Pavel Strnad from Aachen.

🏨 disriminate APAP from non-APAP
📉 predict transplant-free survival from 🩸
🧮 outperform MELD and AFLSG-PI

Great work 👏 doi.org/10.1016/j.jh...
Redirecting
doi.org
February 18, 2025 at 1:43 PM
Reposted
janclusmann.bsky.social
The autoimmune hepatitis field is quite unique in the way clinicians and researchers on AIH are connected personally worldwide. Optimal starting point for generalizable prediction algorithms ...
February 18, 2025 at 1:30 PM
bastianengel.bsky.social
Starting on Bluesky with our summary about most pressing issues in #AIH

🤖 Employing AI for research and patient information
🧬 Unveil pathogenesis by using single cell techniques
🧪 new biomarkers, validate candidates
📊 New clinical trials, harmonize outcome sets

www.jhep-reports.eu/article/S258...
Quo vadis autoimmune hepatitis? - Summary of the 5th international autoimmune hepatitis group research workshop 2024
Autoimmune hepatitis (AIH) is a rare chronic liver disease with an increasing incidence in many countries. Chronic autoimmune responses against the liver can cause hepatic and extrahepatic symptoms, d...
www.jhep-reports.eu
February 18, 2025 at 1:19 PM
Reposted
natureportfolio.nature.com
Two papers in Nature Climate Change suggest that exceeding 1.5 °C in 2024 may indicate that we have entered a multi-decadal period of 1.5 °C average global warming.
https://go.nature.com/4hR9GYO
https://go.nature.com/3WVdJM1
🧪
This is figure 2 from “A year above 1.5 °C signals that Earth is most probably within the 20-year period that will reach the Paris Agreement limit.” It shows strong warming trends place the first 1.5 °C year within the 1.5 °C 20-year period.
February 10, 2025 at 8:12 PM
Reposted
robbrierley.bsky.social
Thermal ablation vs surgical resection of small colorectal liver metastases (COLLISION trial)

“The assumption that thermal ablation should be reserved for unresectable colorectal liver mets requires re-evaluation”

www.thelancet.com/journals/lan...

#GastroSky #OncSky #MedSky @oncoalert.bsky.social
January 21, 2025 at 8:26 AM