Barbara Hollunder
@barbarahollunder.bsky.social
Postdoc @ the Center for Brain Circuit Therapeutics, Brigham & Women’s Hospital, Harvard Medical School I Psychotherapist in training I Passionate about causal brain mapping & science illustration I Cyclophile fueled by cardamom tea.
Reposted by Barbara Hollunder
Thrilled to share my very first publication, in Translational Psychiatry! 🧠🧪
We used invasive brain mapping to identify personalized neuromodulation targets for treatment-refractory OCD.
Read it here 👉 www.nature.com/articles/s41...
#OCD #DBS #Neuroscience #Research
We used invasive brain mapping to identify personalized neuromodulation targets for treatment-refractory OCD.
Read it here 👉 www.nature.com/articles/s41...
#OCD #DBS #Neuroscience #Research
Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity - Translational Psychiatry
Translational Psychiatry - Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity
www.nature.com
November 4, 2025 at 12:41 PM
Thrilled to share my very first publication, in Translational Psychiatry! 🧠🧪
We used invasive brain mapping to identify personalized neuromodulation targets for treatment-refractory OCD.
Read it here 👉 www.nature.com/articles/s41...
#OCD #DBS #Neuroscience #Research
We used invasive brain mapping to identify personalized neuromodulation targets for treatment-refractory OCD.
Read it here 👉 www.nature.com/articles/s41...
#OCD #DBS #Neuroscience #Research
Reposted by Barbara Hollunder
Super excited for Ningfei Li to receive the highly prestigious NSFC Excellent Young Scientists Fund – as of yesterday, Ningfei is Full Professor at the Xian University and has joined a new AI institute! We are both excited to continue our collaboration on @lead-dbs.org and connectomic DBS!
August 18, 2025 at 9:25 AM
Super excited for Ningfei Li to receive the highly prestigious NSFC Excellent Young Scientists Fund – as of yesterday, Ningfei is Full Professor at the Xian University and has joined a new AI institute! We are both excited to continue our collaboration on @lead-dbs.org and connectomic DBS!
Reposted by Barbara Hollunder
Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b
A human brain network linked to restoration of consciousness after deep brain stimulation - Nature Communications
In people with severe brain injuries, stimulation restored consciousness by engaging a deep brain circuit for wakefulness—revealing a target that may also guide treatment in stroke and epilepsy.
www.nature.com
July 21, 2025 at 9:39 PM
Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b
Reposted by Barbara Hollunder
@foxmdphd.bsky.social's legendary anticorrelation paper has now been cited over 10.000 times and this was reason for a dedicated PNAS cake. Congratulations again, Mike, for this unbelievable pioneering effort that opened up the then novel field of resting-state fMRI!
@braincircuits.bsky.social
@braincircuits.bsky.social
June 2, 2025 at 9:49 AM
@foxmdphd.bsky.social's legendary anticorrelation paper has now been cited over 10.000 times and this was reason for a dedicated PNAS cake. Congratulations again, Mike, for this unbelievable pioneering effort that opened up the then novel field of resting-state fMRI!
@braincircuits.bsky.social
@braincircuits.bsky.social
Reposted by Barbara Hollunder
May 30, 2025 at 3:59 PM
Reposted by Barbara Hollunder
Hard to keep track about all the great things our labmembers have achieved recently:
May 29, 2025 at 4:16 PM
Hard to keep track about all the great things our labmembers have achieved recently:
Reposted by Barbara Hollunder
Now available in typeset form - gift link to study: www.sciencedirect.com/science/arti...
May 16, 2025 at 7:15 AM
Now available in typeset form - gift link to study: www.sciencedirect.com/science/arti...
Reposted by Barbara Hollunder
Very hard to say goodbye to these fantastic people.
I will miss you guys! @braincircuits.bsky.social!
I will miss you guys! @braincircuits.bsky.social!
April 16, 2025 at 12:54 AM
Very hard to say goodbye to these fantastic people.
I will miss you guys! @braincircuits.bsky.social!
I will miss you guys! @braincircuits.bsky.social!
Reposted by Barbara Hollunder
Probably the most insightful and most important paper on physiomarkers of subthalamic DBS in a long while. Bravo @julianneumann.bsky.social @tsbinns.com and team!!
Out at @natcomms.nature.com:
www.nature.com/articles/s41...
Out at @natcomms.nature.com:
www.nature.com/articles/s41...
April 16, 2025 at 12:50 AM
Probably the most insightful and most important paper on physiomarkers of subthalamic DBS in a long while. Bravo @julianneumann.bsky.social @tsbinns.com and team!!
Out at @natcomms.nature.com:
www.nature.com/articles/s41...
Out at @natcomms.nature.com:
www.nature.com/articles/s41...
Reposted by Barbara Hollunder
In this month’s “Liftoff,” Thomas Elston talks about the need for new PIs to develop their ability to cultivate others' thinking, and @taylersheahan.bsky.social explains how opening a lab is a lot like early parenthood.
By @franciscorr25.bsky.social
#neuroskyence
bit.ly/4j7G1f3
By @franciscorr25.bsky.social
#neuroskyence
bit.ly/4j7G1f3
Liftoff: New lab alerts
Learn about early-career scientists starting their own labs.
bit.ly
April 15, 2025 at 2:29 PM
In this month’s “Liftoff,” Thomas Elston talks about the need for new PIs to develop their ability to cultivate others' thinking, and @taylersheahan.bsky.social explains how opening a lab is a lot like early parenthood.
By @franciscorr25.bsky.social
#neuroskyence
bit.ly/4j7G1f3
By @franciscorr25.bsky.social
#neuroskyence
bit.ly/4j7G1f3
Reposted by Barbara Hollunder
Was fun to do a podcast about our recent paper on creativity and brain disease with Dr Norman Swan @abcnewsbot.bsky.social @braincircuits.bsky.social @foxmdphd.bsky.social @harvardmed.bsky.social www.abc.net.au/listen/progr...
What brain damage tells us about creativity - ABC listen
Scientists have long been aware of a paradox of neurodegenerative disease – that as the brain deteriorates, in some patients creativity flourishes.
Researchers have used imaging techniques to map cre...
www.abc.net.au
March 30, 2025 at 1:02 PM
Was fun to do a podcast about our recent paper on creativity and brain disease with Dr Norman Swan @abcnewsbot.bsky.social @braincircuits.bsky.social @foxmdphd.bsky.social @harvardmed.bsky.social www.abc.net.au/listen/progr...
Looking for an awesome postdoc opportunity in neurophysiology and neuromodulation? Then check out this exciting opening! You’ll work on cutting-edge research, all while being mentored by @carinaoehrn.bsky.social – one of the most talented and fun people around. Can’t beat that!
March 29, 2025 at 1:17 AM
Looking for an awesome postdoc opportunity in neurophysiology and neuromodulation? Then check out this exciting opening! You’ll work on cutting-edge research, all while being mentored by @carinaoehrn.bsky.social – one of the most talented and fun people around. Can’t beat that!
Reposted by Barbara Hollunder
I learned so much from a very sharp mind in this conversation. Equipped w an undergrad mathematics at Harvard, Medschool at Harvard, PhD at MIT, Terry has begun deeply thinking about dystonia and neuromodulation early on and has come up with a very unique sEEG based approach to treat tough cases.
We had a wonderful conversation with Dr. Terry Sanger from CHOC who is a very inspirational figure and innovator in the field of DBS – with a special focus on treating pediatric forms dystonia / cerebral palsy.
Tune in here 👇👇
stimulatingbrains.org/69-terrence-...
Tune in here 👇👇
stimulatingbrains.org/69-terrence-...
March 27, 2025 at 12:41 PM
I learned so much from a very sharp mind in this conversation. Equipped w an undergrad mathematics at Harvard, Medschool at Harvard, PhD at MIT, Terry has begun deeply thinking about dystonia and neuromodulation early on and has come up with a very unique sEEG based approach to treat tough cases.
Reposted by Barbara Hollunder
Check out our latest release of Stimulating Brains with a introduction recorded by a newcomer 😏! Dr. Sanger talked about how his background in neuroscience, engineering and clinical experiences shaped his path to become one of the top pediatric neurologists. Stay tuned 🥳🥳🥳
I learned so much from a very sharp mind in this conversation. Equipped w an undergrad mathematics at Harvard, Medschool at Harvard, PhD at MIT, Terry has begun deeply thinking about dystonia and neuromodulation early on and has come up with a very unique sEEG based approach to treat tough cases.
We had a wonderful conversation with Dr. Terry Sanger from CHOC who is a very inspirational figure and innovator in the field of DBS – with a special focus on treating pediatric forms dystonia / cerebral palsy.
Tune in here 👇👇
stimulatingbrains.org/69-terrence-...
Tune in here 👇👇
stimulatingbrains.org/69-terrence-...
March 27, 2025 at 1:26 PM
Check out our latest release of Stimulating Brains with a introduction recorded by a newcomer 😏! Dr. Sanger talked about how his background in neuroscience, engineering and clinical experiences shaped his path to become one of the top pediatric neurologists. Stay tuned 🥳🥳🥳
Reposted by Barbara Hollunder
Is generalized epilepsy a seizure of the whole brain or a specific brain network?
In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome.
Paper: nature.com/articles/s41...
A 🧵 below:
In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome.
Paper: nature.com/articles/s41...
A 🧵 below:
A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications
Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...
nature.com
March 24, 2025 at 4:01 PM
Is generalized epilepsy a seizure of the whole brain or a specific brain network?
In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome.
Paper: nature.com/articles/s41...
A 🧵 below:
In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome.
Paper: nature.com/articles/s41...
A 🧵 below:
Reposted by Barbara Hollunder
We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1...
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March 20, 2025 at 5:14 PM
We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1...
1/n
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Reposted by Barbara Hollunder
Had a really insightful conversation with @toddherrington.bsky.social, the director of the DBS program at @massgeneralbrigham.bsky.social MGH about adaptive DBS, stem cell research and novel forms of neuromodulation! Tune in here 👇🎧👇🎧
Adaptive DBS was recently approved by the FDA – in this episode, we talk with @toddherrington.bsky.social about the underlying ADAPT-PD trial, the mechanism of action of DBS, and the potential role of stem cell therapy in movement disorders. Tune in here 👇🎧👇🎧
stimulatingbrains.org/68-todd-herr...
stimulatingbrains.org/68-todd-herr...
March 18, 2025 at 3:05 AM
Had a really insightful conversation with @toddherrington.bsky.social, the director of the DBS program at @massgeneralbrigham.bsky.social MGH about adaptive DBS, stem cell research and novel forms of neuromodulation! Tune in here 👇🎧👇🎧
Reposted by Barbara Hollunder
Happy to share our most recent paper about the neural underpinnings of essential tremor. We mapped tremor-related changes of thalamocortical coupling and provide evidence for thalamo-cerebellar synchronization. Congrats to 1st author Alex Steina and thank u Düsseldorf team! doi.org/10.1002/mds....
Oscillatory Coupling Between Thalamus, Cerebellum, and Motor Cortex in Essential Tremor
Background
Essential tremor is hypothesized to emerge from synchronized oscillatory activity within the cerebello-thalamo-cortical circuit. However, this hypothesis has not yet been tested using loc.....
doi.org
March 17, 2025 at 4:41 PM
Happy to share our most recent paper about the neural underpinnings of essential tremor. We mapped tremor-related changes of thalamocortical coupling and provide evidence for thalamo-cerebellar synchronization. Congrats to 1st author Alex Steina and thank u Düsseldorf team! doi.org/10.1002/mds....
Reposted by Barbara Hollunder
If a doctor is going to stimulate your brain, should they receive special training first? Congrats @shansiddiqi.bsky.social @braincircuits.bsky.social on leading this effort to make brain stimulation a certified clinical subspecialty: www.sciencedirect.com/science/arti...
Towards accredited clinical training in brain stimulation: Proceedings from the brain stimulation subspecialty summits
The rapid development and clinical use of brain stimulation has renewed debates about whether to define and accredit a pathway for clinical subspecial…
www.sciencedirect.com
March 7, 2025 at 12:45 PM
If a doctor is going to stimulate your brain, should they receive special training first? Congrats @shansiddiqi.bsky.social @braincircuits.bsky.social on leading this effort to make brain stimulation a certified clinical subspecialty: www.sciencedirect.com/science/arti...
Reposted by Barbara Hollunder
Want to learn DBS electrode localization with @lead-dbs.org while being able to verify your results?
This new tool from the @netstim.org lab lets you compare your performance against experts.
Spearheaded by Savir Madan & @laurenahart.bsky.social
This new tool from the @netstim.org lab lets you compare your performance against experts.
Spearheaded by Savir Madan & @laurenahart.bsky.social
Madan and Hart et al. introduce Lead-Tutor, an open-access educational resource that combines an imaging dataset of anonymized DBS cases with a software tool for self-teaching: doi.org/10.52294/001...
@laurenahart.bsky.social @andreashorn.org @jordytasserie.bsky.social @ohbmofficial.bsky.social
@laurenahart.bsky.social @andreashorn.org @jordytasserie.bsky.social @ohbmofficial.bsky.social
March 1, 2025 at 7:37 AM
Want to learn DBS electrode localization with @lead-dbs.org while being able to verify your results?
This new tool from the @netstim.org lab lets you compare your performance against experts.
Spearheaded by Savir Madan & @laurenahart.bsky.social
This new tool from the @netstim.org lab lets you compare your performance against experts.
Spearheaded by Savir Madan & @laurenahart.bsky.social
Reposted by Barbara Hollunder
Madan and Hart et al. introduce Lead-Tutor, an open-access educational resource that combines an imaging dataset of anonymized DBS cases with a software tool for self-teaching: doi.org/10.52294/001...
@laurenahart.bsky.social @andreashorn.org @jordytasserie.bsky.social @ohbmofficial.bsky.social
@laurenahart.bsky.social @andreashorn.org @jordytasserie.bsky.social @ohbmofficial.bsky.social
February 28, 2025 at 3:34 PM
Madan and Hart et al. introduce Lead-Tutor, an open-access educational resource that combines an imaging dataset of anonymized DBS cases with a software tool for self-teaching: doi.org/10.52294/001...
@laurenahart.bsky.social @andreashorn.org @jordytasserie.bsky.social @ohbmofficial.bsky.social
@laurenahart.bsky.social @andreashorn.org @jordytasserie.bsky.social @ohbmofficial.bsky.social
Reposted by Barbara Hollunder
Lead-DBS v3.2 is out now – featuring Lead-Tutor, lots of code fixes and improvements, as well as some new atlases. Read all about it here:
www.lead-dbs.org?na=view&id=31
www.lead-dbs.org?na=view&id=31
March 2, 2025 at 9:29 PM
Lead-DBS v3.2 is out now – featuring Lead-Tutor, lots of code fixes and improvements, as well as some new atlases. Read all about it here:
www.lead-dbs.org?na=view&id=31
www.lead-dbs.org?na=view&id=31
Reposted by Barbara Hollunder
Excited to have my PhD project paper exploring the network mechanisms of neuromodulation accepted for publication!
We show how deep brain stimulation and medication exert a shared modulation of motor network synchrony in Parkinson's disease.
We show how deep brain stimulation and medication exert a shared modulation of motor network synchrony in Parkinson's disease.
February 18, 2025 at 2:52 PM
Excited to have my PhD project paper exploring the network mechanisms of neuromodulation accepted for publication!
We show how deep brain stimulation and medication exert a shared modulation of motor network synchrony in Parkinson's disease.
We show how deep brain stimulation and medication exert a shared modulation of motor network synchrony in Parkinson's disease.
Reposted by Barbara Hollunder
I’m so thrilled to finally share the news of my NIH NINDS K99/R00 Pathway to Independence award!!! 🎉💃🏼 Long awaited and a little beam of light amidst the chaos and impending doom 😅 Words cannot express how much this opportunity to launch the next phase of my career means to me. A few notes below...
February 19, 2025 at 9:19 PM
I’m so thrilled to finally share the news of my NIH NINDS K99/R00 Pathway to Independence award!!! 🎉💃🏼 Long awaited and a little beam of light amidst the chaos and impending doom 😅 Words cannot express how much this opportunity to launch the next phase of my career means to me. A few notes below...
Reposted by Barbara Hollunder
En route to Kobe already! 🇯🇵
Who else is coming? Folks interested in joining the lab (and everyone else of course) feel free to approach me!
Who else is coming? Folks interested in joining the lab (and everyone else of course) feel free to approach me!
February 19, 2025 at 2:15 PM
En route to Kobe already! 🇯🇵
Who else is coming? Folks interested in joining the lab (and everyone else of course) feel free to approach me!
Who else is coming? Folks interested in joining the lab (and everyone else of course) feel free to approach me!