Audrey Luo
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audreycluo.bsky.social
Audrey Luo
@audreycluo.bsky.social
MD/PhD Candidate @PennMedicine studying functional connectivity & white matter development at PennLINC 🧠 previously @Yale
Pinned
So grateful to @ted-satterthwaite.bsky.social for being the most wonderful PhD adviser and @pennlinc.bsky.social for being my lab home. My heart is full 🩷🧡💛
CONGRATS TO DOCTOR @audreycluo.bsky.social !!! Last week, Dr. Luo knocked our collective socks off with a thesis defense for the ages. Her presentation on "Axes of Hierarchical Brain Development" was magnificent -- beautiful science, presented in an incredibly accessible and engaging way. WOO!!!!
Reposted by Audrey Luo
🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵

nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function
Nature Neuroscience - Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI...
nature.com
October 15, 2025 at 8:18 PM
Reposted by Audrey Luo
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉

📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
September 22, 2025 at 9:51 PM
Reposted by Audrey Luo
New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇

www.biorxiv.org/cgi/content/...
September 7, 2025 at 2:59 PM
Reposted by Audrey Luo
🍄 Our new living systematic review and meta-analysis on psilocybin for depression is out. Here's what we found and the open science infrastructure we built to support it 🧪🧵
www.medrxiv.org/content/10.1...
August 18, 2025 at 1:17 PM
Reposted by Audrey Luo
Congrats @audreycluo.bsky.social!! Celebrating a wonderful dissertation defense that shed novel, fundamental, and convincing insights into white matter development.
CONGRATS TO DOCTOR @audreycluo.bsky.social !!! Last week, Dr. Luo knocked our collective socks off with a thesis defense for the ages. Her presentation on "Axes of Hierarchical Brain Development" was magnificent -- beautiful science, presented in an incredibly accessible and engaging way. WOO!!!!
August 14, 2025 at 9:14 PM
Reposted by Audrey Luo
@audreycluo.bsky.social has had one of the most impressive graduate careers I've ever seen. Kudos!!!!
CONGRATS TO DOCTOR @audreycluo.bsky.social !!! Last week, Dr. Luo knocked our collective socks off with a thesis defense for the ages. Her presentation on "Axes of Hierarchical Brain Development" was magnificent -- beautiful science, presented in an incredibly accessible and engaging way. WOO!!!!
August 14, 2025 at 10:47 PM
So grateful to @ted-satterthwaite.bsky.social for being the most wonderful PhD adviser and @pennlinc.bsky.social for being my lab home. My heart is full 🩷🧡💛
CONGRATS TO DOCTOR @audreycluo.bsky.social !!! Last week, Dr. Luo knocked our collective socks off with a thesis defense for the ages. Her presentation on "Axes of Hierarchical Brain Development" was magnificent -- beautiful science, presented in an incredibly accessible and engaging way. WOO!!!!
August 15, 2025 at 4:14 PM
Reposted by Audrey Luo
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...

Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
August 4, 2025 at 2:27 PM
Reposted by Audrey Luo
#NGG is proud to present our next Thesis Defense given by Audrey Luo @audreycluo.bsky.social of the Satterthwaite Lab
@ted-satterthwaite.bsky.social ! Please join us in person or virtually (DM us for the link) on 8/5. Best of luck, Audrey! #PhAlmostDone 🥳
July 29, 2025 at 8:40 PM
Such beautiful and careful work from @valeriejsydnor.bsky.social, as always!!
How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...
July 9, 2025 at 4:30 PM
Reposted by Audrey Luo
The ABCD Study 6.0 release is finally here! 🧠 Apply for data access here @theabcdstudy.bsky.social www.nbdc-datahub.org
NBDC Data Hub
NIH Brain Development Cohorts (NBDC) Data Sharing Platform: Unifying ABCD and HBCD data management in one powerful platform.
www.nbdc-datahub.org
June 26, 2025 at 11:16 PM
Reposted by Audrey Luo
Alert! ... for the child development world!

@fluxsociety.bsky.social @fitngin.bsky.social

The Healthy Brain and Child Development (HBCD) Study has released its first data wave - it’s massive.

Check here:
docs.hbcdstudy.org

and here:
nbdc-datahub.org

Here’s why it matters 🧠🍼
June 29, 2025 at 2:18 AM
Reposted by Audrey Luo
@kevin-y-sun.bsky.social‬ will be presenting his work on "Copy Number Variant Risk Scores Are Associated with Personalized Functional Brain Network Topography" Wed, June 25, 13:15 - 15:15 & Thus, June 26, 13:45 - 15:45
June 25, 2025 at 12:50 AM
Reposted by Audrey Luo
#OHBM2025 is here and the champs from @pennlinc.bsky.social have brought their freshest work express from Philly to Brisbane. Thread below . . .please reach out + come say hi -- always looking to talk science + make new friends!!!
a cartoon of snoopy dancing with the words oh yeah written above him
ALT: a cartoon of snoopy dancing with the words oh yeah written above him
media.tenor.com
June 25, 2025 at 12:36 AM
Reposted by Audrey Luo
@audreycluo.bsky.social will be presenting her fab work on "Two Axes of White Matter Development" on Wed, June 25, 13:15 -15:15 & Thurs, June 26, 13:45 -15:45; Poster #1010.
June 25, 2025 at 12:49 AM
Thanks @gradientsworkshop.bsky.social for a fantastic day of science and for inviting me to speak!! 🌈🧠
@audreycluo.bsky.social giving a great talk on two major axes of white matter development at Gradients Workshop #OHBM
June 23, 2025 at 8:12 AM
Reposted by Audrey Luo
So excited to share that my first paper is out in BMJ Open! Thank you @ballerlab.bsky.social and the amazing team of people that made this possible! 🧠🌟
June 3, 2025 at 8:14 PM
Reposted by Audrey Luo
The Baller Lab is thrilled to announce that @elenaccooper.bsky.social just had her first first-author publication! “Investigating mood and cognition in people with multiple sclerosis: a prospective cross-sectional study protocol” is now published on BMJ Open: bmjopen.bmj.com/content/15/5/e094733! 🧠
Investigating mood and cognition in people with multiple sclerosis: a prospective cross-sectional study protocol
Introduction Multiple sclerosis (MS) is an immune-mediated neurological disorder that affects one million people in the USA. Up to 50% of patients with MS experience depression, yet the mechanisms of ...
bmjopen.bmj.com
June 3, 2025 at 8:09 PM
Reposted by Audrey Luo
Hot off the press! We found that electroconvulsive therapy (ECT) induces a previously undescribed, second brain event after seizure, called cortical spreading depolarization (CSD), using optical neuroimaging in both a mouse model to human patients. 🧵 below!

doi.org/10.1038/s414...
Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans - Nature Communications
The underlying mechanism of electroconvulsive therapy remains not fully understood. Here, the authors use optical neuroimaging in mice and humans to show that electroconvulsive therapy elicits a secon...
doi.org
May 18, 2025 at 6:03 PM
Reposted by Audrey Luo
Dreaming of a dataset that tracks mood, sleep & activity to better understand affective instability (AI)…AND paired with advanced MRI? 🤯
Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...
May 6, 2025 at 3:32 PM
Reposted by Audrey Luo
I am so heartened to this seriously AWESOME #SaveNSF website go up today!!!!

Has a take action toolkit with:

1. Press outreach templates
2. Social media toolkit
3. Elected official outreach
4. Talking points

Check it out and share widely!!!! Likely more to come.

www.savensf.com
May 2, 2025 at 10:08 PM
Reposted by Audrey Luo
Excited to share that our paper is now in press at the British Journal of Psychiatry! Looking forward to presenting our work this Friday at #SOBP2025 in our symposium: "Does one size fit all? Subgroup Modeling of Brain-Behavior Relationships in Psychiatry" 🧠

#neuroskyence #neuroimaging #psychscisky
✨New Preprint!✨ Sex differences in psychiatric disorders often show up in adolescence as disparities in prevalence, symptoms, and treatment outcomes. We aimed to understand sex diffs in brain organization that might lead to these disparities!
t.ly/x6oxC
🧵⬇️
#neuroskyence #psychscisky #Neuroimaging
Reproducible Sex Differences in Personalized Functional Network Topography in Youth
Background A key step towards understanding psychiatric disorders that disproportionately impact female mental health is delineating the emergence of sex-specific patterns of brain organization at the...
t.ly
April 22, 2025 at 8:13 PM
Reposted by Audrey Luo
Study human brain structure and function with our new open access 7T MRI dataset

led by superstar scientist @donnagift.bsky.social ↙️
March 30, 2025 at 3:39 PM
🥹🥹🥹
Am beyond delighted to see this preprint now up from superstar PennLINC MD-PhD student @audreycluo.bsky.social. Audrey shows in three big datasets that major WM tracts develop according to two major axes. This ambitious project was her vision from start to finish -- pure joy see it unfold.
We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1...
1/n
March 21, 2025 at 12:41 AM