ArthurMageau
arthurmageau.bsky.social
ArthurMageau
@arthurmageau.bsky.social
Interniste à Bichat 🐈🐈 🏥
What are the main radiologic features of #SLE associated ILD ?
Check our new study, just relased in @europeanradiology.bsky.social
#MedSky
Great to collaborate with Radiologists and Pulmonologists from @hopitalbichat.bsky.social
@raphaelborie.bsky.social

doi.org/10.1007/s003...
CT features of interstitial lung disease in systemic lupus erythematosus and overlap lupus-other connective tissue disease - European Radiology
Objectives To describe initial and follow-up CT features of chronic interstitial lung disease (cILD) associated with systemic lupus erythematosus (SLE), focusing on variant signs of lung fibrosis. Mat...
doi.org
November 23, 2025 at 8:27 PM
Congratulations 👏 👏 @clemencedavid.bsky.social for this publication in #ARD 📚

Physicians should know this monogenic autoinflammatory entity thaht affects lung, joints and kidney but not only those organs !

doi.org/10.1016/j.ar...
Redirecting
doi.org
November 7, 2025 at 9:51 AM
Reposted by ArthurMageau
Nature research paper: Humoral determinants of checkpoint immunotherapy

go.nature.com/41a8fin
Humoral determinants of checkpoint immunotherapy - Nature
Rapid extracellular antibody profiling reveals a contribution of autoantibodies to the effectiveness of checkpoint immunotherapy for cancer.
go.nature.com
July 27, 2025 at 2:29 PM
Congratulations 👏👏 Ngoc and @elizabetharkema.bsky.social ! These data are important in helping us to select the most suitable immunosuppressant during pregnancy. #Medsky

Looking forward to future collaborations 🙂 🇸🇪🇺🇸🇻🇳🇫🇷 !
July 24, 2025 at 6:24 AM
Reposted by ArthurMageau
Two patients with monoclonal anti-PF4 antibodies, thrombosis, and chronic thrombocytopenia also had first-trimester pregnancy losses, findings that suggest a possible link between these antibodies and obstetrical complications. Read the full report: nej.md/4luAlx1

#MedSky #OBGYN
Monoclonal Anti–Platelet Factor 4 Antibodies in Recurrent Pregnancy Loss | NEJM
Two patients with monoclonal anti-PF4 antibodies, thrombosis, and chronic thrombocytopenia also had first-trimester pregnancy losses, findings that suggest a possible link between these antibodies ...
nej.md
July 21, 2025 at 3:04 PM
Congratulations 👏👏 to @mimrobert.bsky.social for this very nice work 🗞
It seems worthy to look at anti-13 antibody during the follow-up of #iTTP . Maybe to guide anti-CD20 therapy ?
#Medsky
@amjh.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
Anti‐ADAMTS13 Antibodies Trajectory is Associated With ADAMTS13 Recovery in Immune‐Mediated TTP
Anti-ADAMTS13 IgG antibodies titer trajectory from baseline to day 7–14 post-TPE as a reliable approach to identify iTTP patients at risk of late response to the triplet therapy regimen.
onlinelibrary.wiley.com
July 16, 2025 at 7:10 PM
Reposted by ArthurMageau
🌞 Un air d’été à l’hôpital Bichat – Claude-Bernard @ap-hp.bsky.social !
Ce midi, l’hôpital a célébré l’arrivée de l’été avec un déjeuner estival en musique, au jardin de la crèche du secteur Claude-Bernard 🎶🍔🌿
June 26, 2025 at 5:06 PM
BCMA CAR T therapy to treat autoimmune cytopenias resistant to CD19 CAR T...🤯

Sounds like sci-fi but it is already there in @nejm.org !

Is this really the future of clinical immunology ?

Let's wait and find out !
nejm.org NEJM.org @nejm.org · Jun 16
Two patients had autoimmune hemolytic anemia that relapsed after CD19 CAR T-cell therapy but responded rapidly to BCMA-targeted T-cell–engager therapy with remission, minimal side effects, and hematologic improvement. Learn more: nej.md/3SM6S4V

#MedSky #Immunology
June 16, 2025 at 8:38 PM
Reposted by ArthurMageau
Betw 2005 -2021, there was a substantial increase in HCQ use, but only modest steroid (GC) reductions. Swedish cohort study of 3891 SLE pts - over 5 yrs GC decr from 68% - 54% to 46%. HCQ increased by 29% over 5 years. buff.ly/7HudhKH
May 14, 2025 at 4:00 AM
Looking for subliclinical atherosclerosis with vascular ultrasound could help us stratify the cardiovascular🩺 risk in #SLE #MedSky

@lupusjournal 🗞
@hopitalbichat.bsky.social 🏥

doi.org/10.1177/0961...
Subclinical atherosclerosis is associated with future cardiovascular events in lupus patients at apparent low cardiovascular risk - Arthur Mageau, Florence Arnoult, Marie-Paule Chauveheid, Thomas Papo...
Objectives Prediction models based on traditional risk factors underestimate the risk for cardiovascular events (CVE) in SLE. We aimed to assess the occurrence ...
doi.org
May 15, 2025 at 11:08 AM
Reposted by ArthurMageau
Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. Learn more in a new review: nej.md/42gEZYk

#MedSky #GastroSky
April 30, 2025 at 1:27 PM
Reposted by ArthurMageau
Human papillomavirus et lupus systémique : une revue systématique
www.sciencedirect.com/science/arti...
#SLE #HPV
March 23, 2025 at 8:55 PM
Congratulations 👏👏 to @AnnicaDominicus and @elizabetharkema.bsky.social for this useful work about temporal trends📉 in GC and HCQ for treatment of #SLE 🦋.

Are our practices in line with the evolution of treatment recommendations? Let's find out :

doi.org/10.1093/rheu...
Temporal trends in glucocorticoids and hydroxychloroquine for treatment of systemic lupus erythematosus in Sweden
AbstractObjectives. It is unknown to what extent updated treatment recommendations regarding glucocorticoids (GC) and hydroxychloroquine (HCQ) for patients
doi.org
April 13, 2025 at 1:40 PM
We need safety 🦺 data regarding elderly patients with #GCA but this looks very interesting :

@nejm.org #Medsky

A Phase 3 Trial of Upadacitinib for Giant-Cell Arteritis | New England Journal of Medicine www.nejm.org/doi/full/10....
A Phase 3 Trial of Upadacitinib for Giant-Cell Arteritis | NEJM
Giant-cell arteritis is a systemic vasculitis with limited treatment options. The efficacy and safety of upadacitinib — a selective Janus kinase (JAK) inhibitor that blocks the signaling of several...
www.nejm.org
April 3, 2025 at 12:42 PM
Reposted by ArthurMageau
Absolute iron deficiency affects approximately 2 billion people worldwide.

This narrative review examines the screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia.

#ACC25 https://ja.ma/3Xw1i9K
March 30, 2025 at 1:45 PM
Reposted by ArthurMageau
J&J announced the FDA jas granted the investigational drug, nipocalimab (FcRn recpt Ab), with Fast Track designation for its study in adult patients with moderate-to-severe Sjögren’s disease buff.ly/SFYky98
March 22, 2025 at 8:00 PM
Does tolerance for uncertainty 🤷 affect medical students' specialty choice ? #Medsky @medicaleducation.bsky.social
I used to think that internal medicine or emergency medicine physicians had a better tolerance than others...

asmepublications.onlinelibrary.wiley.com/doi/10.1111/...
Tolerance for uncertainty and medical students' specialty choices: A myth revisited
Background In 1962, the idea emerged that medical students' tolerance of uncertainty could determine their specialty choice. While some studies supported this claim, others refuted it, often using i...
asmepublications.onlinelibrary.wiley.com
March 21, 2025 at 11:45 AM
An old new immunosuppressant 💊 for lupus nephritis ? Mizoribine vs CYC in this original study #MedSky @jama.com . In the era of Mabs, it is quite unexpected !

jamanetwork.com/journals/jam...
Mizoribine or Cyclophosphamide for Lupus Nephritis
This randomized clinical trial assesses the efficacy and safety of oral mizoribine vs intravenous cyclophosphamide as induction therapy for lupus nephritis among Chinese patients.
jamanetwork.com
March 19, 2025 at 6:37 PM
Reposted by ArthurMageau
Rare PROS1 variants significantly increase venous thromboembolism risk, revealing low protein S as a key factor in thrombotic disorders.

by Chaudhry SA, Haj AK (...) Bendapudi PK et 9 al. in JAMA #MedSky

📖 read the article:
Population-Scale Studies of Protein S Abnormalities and Thrombosis
This cross-sectional study evaluates the risk associated with protein S deficiency across multiple arterial thrombosis phenotypes in population-level cohorts.
jamanetwork.com
March 12, 2025 at 6:38 PM
Could we use serum type I interferon score for prediction of disease progression in limited cutaneous systemic sclerosis ? Retrospective data look convincing enven if they need to be reproduced in a different setting. #Medsky

📰:
acrjournals.onlinelibrary.wiley.com/share/UNQCUF...
Serum Type I Interferon Score for Prediction of Clinically Meaningful Disease Progression in Limited Cutaneous Systemic Sclerosis
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acrjournals.onlinelibrary.wiley.com
March 9, 2025 at 7:45 AM
What are the clinical presentation and outcomes of adult patients with immune mediated inflammatory disease who were hospitalised following an ED referral 🚑 ? Find out in this study from @ElisaChapuis 👏 #MedSky @hopitalbichat.bsky.social
rdcu.be/eb54T
Hospital admission from the emergency department of adult patients affected by immune-mediated inflammatory diseases: a multidimensional retrospective analysis of an hospital-based cohort
rdcu.be
March 4, 2025 at 7:19 AM
Reposted by ArthurMageau
"L’Ordre des médecins, mis en cause pour son attitude face au chirurgien pédocriminel Joël Le Scouarnec, est chargé d’assurer la discipline dans la profession médicale. Il est régulièrement accusé d’avoir une approche corporatiste et conservatrice."
www.lanouvellerepublique.fr/a-la-une/l-o...
L’Ordre des médecins, un gendarme professionnel régulièrement accusé de corporatisme et de conservatisme
L’Ordre des médecins, mis en cause pour son attitude face au chirurgien pédocriminel Joël Le Scouarnec, est chargé d’assurer la discipline dans la profession médicale. Il est régulièrement accusé d’av...
www.lanouvellerepublique.fr
March 3, 2025 at 2:49 PM