Annie Tivey
@anntivey.bsky.social
Clinical PhD Fellow/Specialist Registrar in Medical Oncology at Cancer Research UK National Biomarker Centre/University of Manchester. Interests in melanoma, liquid biopsy (and Gloucester Rugby...)
Reposted by Annie Tivey
Very positive spin on #GenerativeAI tools from @nature.com:
www.nature.com/articles/d41...
New to me is @thesify.bsky.social - anyone had any experience using this?
I'm trying to understand the privacy policy re: how inputs (papers, grants) are protected & whether they are used for training AI?
www.nature.com/articles/d41...
New to me is @thesify.bsky.social - anyone had any experience using this?
I'm trying to understand the privacy policy re: how inputs (papers, grants) are protected & whether they are used for training AI?
AI for research: the ultimate guide to choosing the right tool
Curious about using artificial intelligence to boost your research? Here are the programs you shouldn’t miss.
www.nature.com
April 9, 2025 at 4:14 PM
Very positive spin on #GenerativeAI tools from @nature.com:
www.nature.com/articles/d41...
New to me is @thesify.bsky.social - anyone had any experience using this?
I'm trying to understand the privacy policy re: how inputs (papers, grants) are protected & whether they are used for training AI?
www.nature.com/articles/d41...
New to me is @thesify.bsky.social - anyone had any experience using this?
I'm trying to understand the privacy policy re: how inputs (papers, grants) are protected & whether they are used for training AI?
Reposted by Annie Tivey
vimeo.com/1037419193?s...
We are chronically short of blood donors. Please watch Yaseen’s story to help understand how important blood donation is.
We are chronically short of blood donors. Please watch Yaseen’s story to help understand how important blood donation is.
BBC - NHS Blood and Transplant campaign for blood donors
This is "BBC - NHS Blood and Transplant campaign for blood donors" by MFT on Vimeo, the home for high quality videos and the people who love them.
vimeo.com
December 9, 2024 at 4:52 PM
vimeo.com/1037419193?s...
We are chronically short of blood donors. Please watch Yaseen’s story to help understand how important blood donation is.
We are chronically short of blood donors. Please watch Yaseen’s story to help understand how important blood donation is.
ICIs can alter atherosclerotic plaques immune landscape, fascinating and salient insight into the potential long-term 'collateral damage' from these drugs, particularly important as their use in the neo/adjuvant settings rapidly expands www.nature.com/articles/s44...
Immune checkpoint landscape of human atherosclerosis and influence of cardiometabolic factors - Nature Cardiovascular Research
Barcia Durán, Dayasagar, et al. map the expression of immune checkpoints in human atherosclerosis and examine the influence of lipid-lowering treatments and type 2 diabetes to understand how immune ch...
www.nature.com
December 1, 2024 at 11:41 AM
ICIs can alter atherosclerotic plaques immune landscape, fascinating and salient insight into the potential long-term 'collateral damage' from these drugs, particularly important as their use in the neo/adjuvant settings rapidly expands www.nature.com/articles/s44...
Reposted by Annie Tivey
📑 What a comprehensive review! 👏
ICIs have come so far - so many combinatorial strategies. Rational/precision tx & biomarkers remain areas of unmet need. Will AI/ML 🤖 help? So much more to do.
Hopefully our #MANIFEST project (manifest-io.org.uk) can also contribute to this in the coming years.
ICIs have come so far - so many combinatorial strategies. Rational/precision tx & biomarkers remain areas of unmet need. Will AI/ML 🤖 help? So much more to do.
Hopefully our #MANIFEST project (manifest-io.org.uk) can also contribute to this in the coming years.
www.nature.com/articles/s41...
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
Next-generation combination approaches for immune checkpoint therapy - Nature Immunology
In this Review, Sharma and colleagues describe the current landscape of combination therapies and discuss requirements for the development of effective combination strategies.
www.nature.com
November 26, 2024 at 1:26 AM
📑 What a comprehensive review! 👏
ICIs have come so far - so many combinatorial strategies. Rational/precision tx & biomarkers remain areas of unmet need. Will AI/ML 🤖 help? So much more to do.
Hopefully our #MANIFEST project (manifest-io.org.uk) can also contribute to this in the coming years.
ICIs have come so far - so many combinatorial strategies. Rational/precision tx & biomarkers remain areas of unmet need. Will AI/ML 🤖 help? So much more to do.
Hopefully our #MANIFEST project (manifest-io.org.uk) can also contribute to this in the coming years.
Reposted by Annie Tivey
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
Reposted by Annie Tivey
Cancer cells often harbor oncogenes outside chromosomes on extrachromosomal DNA (ecDNA), which is unevenly inherited by dividing cells. We reported in Nature last week that collectives of ecDNAs are inherited together by dividing cancer cells. 1/
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Coordinated inheritance of extrachromosomal DNAs in cancer cells - Nature
Cooperative species of extrachromosomal DNAs are coordinately inherited through mitotic co-segregation.
www.nature.com
November 18, 2024 at 5:37 PM
Cancer cells often harbor oncogenes outside chromosomes on extrachromosomal DNA (ecDNA), which is unevenly inherited by dividing cells. We reported in Nature last week that collectives of ecDNAs are inherited together by dividing cancer cells. 1/
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Annie Tivey
After months in the making, super excited about the official launch of MANIFEST (www.manifest-io.org.uk) 🚀, led by the visionary Samra Turajlic.
Happy to be a co-investigator & delivering parts of the programme as #TeamManchester: UoM, CRUK MI, CRUK NBC & #TheChristie.
Let's get started! 🙌
Happy to be a co-investigator & delivering parts of the programme as #TeamManchester: UoM, CRUK MI, CRUK NBC & #TheChristie.
Let's get started! 🙌
November 15, 2024 at 6:13 PM
After months in the making, super excited about the official launch of MANIFEST (www.manifest-io.org.uk) 🚀, led by the visionary Samra Turajlic.
Happy to be a co-investigator & delivering parts of the programme as #TeamManchester: UoM, CRUK MI, CRUK NBC & #TheChristie.
Let's get started! 🙌
Happy to be a co-investigator & delivering parts of the programme as #TeamManchester: UoM, CRUK MI, CRUK NBC & #TheChristie.
Let's get started! 🙌
Reposted by Annie Tivey
A couple of days left to apply! We have a PhD position available in the lab to improve our understanding of cfDNA and cfRNA shedding from cancer cells, and the potential impact on heterogeneity. #cfDNA #liquidbiopsy #cfRNA
If you're looking for a #PhD in #CancerResearch, we've got fantastic 4-year, fully-funded #PhDpositions available, with registration & graduation affiliated to the University of Manchester, UK
For details of the projects go to:
www.cruk.manchester.ac.uk/Education/Ph...
Closing date: 22nd Nov 2024
For details of the projects go to:
www.cruk.manchester.ac.uk/Education/Ph...
Closing date: 22nd Nov 2024
November 18, 2024 at 9:37 AM
A couple of days left to apply! We have a PhD position available in the lab to improve our understanding of cfDNA and cfRNA shedding from cancer cells, and the potential impact on heterogeneity. #cfDNA #liquidbiopsy #cfRNA
Reposted by Annie Tivey
Before I go to bed let me post an amazing paper by Filipe Pereira’s group (Ervin Ascic et al) for your enjoyment. I think this is a likely fundamental breakthrough in cancer immunotherapy: personalized, yet generic and probably pan-cancer. www.science.org/doi/10.1126/...
In vivo dendritic cell reprogramming for cancer immunotherapy
Immunotherapy can lead to long-term survival for some cancer patients, yet generalized success has been hampered by insufficient antigen presentation and exclusion of immunogenic cells from the tumor ...
www.science.org
November 17, 2024 at 8:47 PM
Before I go to bed let me post an amazing paper by Filipe Pereira’s group (Ervin Ascic et al) for your enjoyment. I think this is a likely fundamental breakthrough in cancer immunotherapy: personalized, yet generic and probably pan-cancer. www.science.org/doi/10.1126/...
Reposted by Annie Tivey
Here's the #Cancer #Research #2 starter pack 🤩
Researchers, oncologists, patient advocates & more -working across all aspects of cancer research and treatment 🧪🔬⚕️
I also tried to give some exposure to #PhD #students & #postdocs - randomly picked from followers of me or my lab!
go.bsky.app/6EcjWNA
Researchers, oncologists, patient advocates & more -working across all aspects of cancer research and treatment 🧪🔬⚕️
I also tried to give some exposure to #PhD #students & #postdocs - randomly picked from followers of me or my lab!
go.bsky.app/6EcjWNA
November 17, 2024 at 6:58 PM
Fascinating read and salient illustrationsof the limitations/dangers of implementing machine learning into clinical decision making. As clinicians we shouldn't be deterred from trying to look inside the 'black box' and understand potential unforeseen consequences. www.aisnakeoil.com/p/does-the-u...
Does the UK’s liver transplant matching algorithm systematically exclude younger patients?
Seemingly minor technical decisions can have life-or-death effects
www.aisnakeoil.com
November 17, 2024 at 5:30 PM
Fascinating read and salient illustrationsof the limitations/dangers of implementing machine learning into clinical decision making. As clinicians we shouldn't be deterred from trying to look inside the 'black box' and understand potential unforeseen consequences. www.aisnakeoil.com/p/does-the-u...
Reposted by Annie Tivey
#ScienceSaturday How can we enhance CAR-T cell activity against solid cancers?
➡️ In a recent study, Zhao et al transduced CAR-T to express IL-10, resulting in enhanced T-cell proliferation, effector function, mitochondrial capacity and antitumor activity in a variety of solid tumor murine models.
➡️ In a recent study, Zhao et al transduced CAR-T to express IL-10, resulting in enhanced T-cell proliferation, effector function, mitochondrial capacity and antitumor activity in a variety of solid tumor murine models.
November 16, 2024 at 4:36 PM
#ScienceSaturday How can we enhance CAR-T cell activity against solid cancers?
➡️ In a recent study, Zhao et al transduced CAR-T to express IL-10, resulting in enhanced T-cell proliferation, effector function, mitochondrial capacity and antitumor activity in a variety of solid tumor murine models.
➡️ In a recent study, Zhao et al transduced CAR-T to express IL-10, resulting in enhanced T-cell proliferation, effector function, mitochondrial capacity and antitumor activity in a variety of solid tumor murine models.
Well this is all rather pleasant and civilised isn't it...
November 16, 2024 at 5:38 PM
Well this is all rather pleasant and civilised isn't it...