Andrew Grotzinger
@andrewgrotzinger.bsky.social
Assistant Professor at CU Boulder interested in multivariate genomic methods development and their application to understanding shared and unique signal across human disease and risk factors.
Reposted by Andrew Grotzinger
Our new preprint is out: "Immune Markers Mediate Genetic Relationships between Immune Diseases and Psychiatric Disorders"! 🧬🦠
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Immune Markers Mediate Genetic Relationships between Immune Diseases and Psychiatric Disorders
This study explored the genetic links between 11 immune-mediated diseases and 13 psychiatric disorders, addressing the limited understanding of what links these illnesses. Utilizing genomic structural...
www.medrxiv.org
October 20, 2025 at 8:08 PM
Our new preprint is out: "Immune Markers Mediate Genetic Relationships between Immune Diseases and Psychiatric Disorders"! 🧬🦠
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Reposted by Andrew Grotzinger
University of Colorado Boulder Department of Psychology & Neuroscience is searching for TWO tenure track assistant professors. This is open to all department areas, including Behavioral, Psychiatric, and Statistical Genetics🧬 jobs.colorado.edu/jobs/JobDeta...
Assistant Professor
jobs.colorado.edu
September 29, 2025 at 3:57 PM
University of Colorado Boulder Department of Psychology & Neuroscience is searching for TWO tenure track assistant professors. This is open to all department areas, including Behavioral, Psychiatric, and Statistical Genetics🧬 jobs.colorado.edu/jobs/JobDeta...
Reposted by Andrew Grotzinger
University of Colorado Boulder Psychology & Neuroscience is searching for TWO tenure track assistant professors!!
jobs.colorado.edu/jobs/JobDeta...
#socialpsychology #cogpsyc #PsychSciSky #PsychJob
#psycjobs #psychology
1/n
jobs.colorado.edu/jobs/JobDeta...
#socialpsychology #cogpsyc #PsychSciSky #PsychJob
#psycjobs #psychology
1/n
Assistant Professor
jobs.colorado.edu
September 22, 2025 at 4:00 PM
University of Colorado Boulder Psychology & Neuroscience is searching for TWO tenure track assistant professors!!
jobs.colorado.edu/jobs/JobDeta...
#socialpsychology #cogpsyc #PsychSciSky #PsychJob
#psycjobs #psychology
1/n
jobs.colorado.edu/jobs/JobDeta...
#socialpsychology #cogpsyc #PsychSciSky #PsychJob
#psycjobs #psychology
1/n
Amazing work from my colleague and postdoc Dr. Isabelle Foote on the genetic architecture of frailty. Encourage you to check it out!!!!
New work in Nature Genetics from IBG members lead by @isyfoote.bsky.social (along with @andrewgrotzinger.bsky.social) examining different measures of frailty using Genomic SEM. Findings reveal six genomic factors with unique biological pathways and clinical correlates. www.nature.com/articles/s41...
Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling - Nature Genetics
Multivariate genome-wide association analyses of the latent genetic architecture of frailty identify one general factor of genetic overlap across all frailty deficits and six factors indexing a shared...
www.nature.com
August 6, 2025 at 4:16 PM
Amazing work from my colleague and postdoc Dr. Isabelle Foote on the genetic architecture of frailty. Encourage you to check it out!!!!
Reposted by Andrew Grotzinger
Some recent data:
- First scores for frailty measurements (@isyfoote.bsky.social & @andrewgrotzinger.bsky.social): www.pgscatalog.org/publication/...
- Comprehensive comparison of type 2 diabetes PGS in Qatari Biobank: www.pgscatalog.org/publication/...
Share PGS 👉 www.PGSCatalog.org/submit!
- First scores for frailty measurements (@isyfoote.bsky.social & @andrewgrotzinger.bsky.social): www.pgscatalog.org/publication/...
- Comprehensive comparison of type 2 diabetes PGS in Qatari Biobank: www.pgscatalog.org/publication/...
Share PGS 👉 www.PGSCatalog.org/submit!
PGS Catalog - Foote IF, Nat Genet (2025) (Publication)
The Polygenic Score (PGS) Catalog is an open database of
published PGS and the relevant metadata needed to apply and evaluate them correctly.
www.pgscatalog.org
August 6, 2025 at 3:33 PM
Some recent data:
- First scores for frailty measurements (@isyfoote.bsky.social & @andrewgrotzinger.bsky.social): www.pgscatalog.org/publication/...
- Comprehensive comparison of type 2 diabetes PGS in Qatari Biobank: www.pgscatalog.org/publication/...
Share PGS 👉 www.PGSCatalog.org/submit!
- First scores for frailty measurements (@isyfoote.bsky.social & @andrewgrotzinger.bsky.social): www.pgscatalog.org/publication/...
- Comprehensive comparison of type 2 diabetes PGS in Qatari Biobank: www.pgscatalog.org/publication/...
Share PGS 👉 www.PGSCatalog.org/submit!
Reposted by Andrew Grotzinger
Check out this new work from IBG graduate student @breunigsophie.bsky.social that applies Genomic SEM to examine the relationship between genomic factors for immune-mediated diseases and psychiatric disorders. www.nature.com/articles/s41...
Examining the genetic links between clusters of immune-mediated diseases and psychiatric disorders - Translational Psychiatry
Translational Psychiatry - Examining the genetic links between clusters of immune-mediated diseases and psychiatric disorders
www.nature.com
July 21, 2025 at 5:11 PM
Check out this new work from IBG graduate student @breunigsophie.bsky.social that applies Genomic SEM to examine the relationship between genomic factors for immune-mediated diseases and psychiatric disorders. www.nature.com/articles/s41...
Reposted by Andrew Grotzinger
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
May 20, 2025 at 10:14 AM
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
Reposted by Andrew Grotzinger
Out today, our method for comparing multivariate genetic architecture across groups of people, called Genomic Structural Invariance: www.nature.com/articles/s41...
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
Comparison of the multivariate genetic architecture of eight major psychiatric disorders across sex - Nature Genetics
Genomic structural invariance, an extension of genomic structural equation modeling, identifies similarities and differences between males and females in the genetic architectures of eight psychiatric...
www.nature.com
March 7, 2025 at 3:21 PM
Out today, our method for comparing multivariate genetic architecture across groups of people, called Genomic Structural Invariance: www.nature.com/articles/s41...
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
(feat: @tuckerdrob.bsky.social @michelnivard.bsky.social @andrewgrotzinger.bsky.social @mijke.bsky.social @jorsmo.bsky.social et al.)
One of my talented graduate students (@breunigsophie.bsky.social) is putting together an immune-psychiatric focused symposium submission for the Behavior Genetics Association 2025 meeting in Atlanta. She needs one more talk to fill the symposium; if interested send me a message!
January 28, 2025 at 9:52 PM
One of my talented graduate students (@breunigsophie.bsky.social) is putting together an immune-psychiatric focused symposium submission for the Behavior Genetics Association 2025 meeting in Atlanta. She needs one more talk to fill the symposium; if interested send me a message!
You've heard of DNA, but what about GNA? Very excited about this preprint with @jgthorp.bsky.social and others that introduces Genomic Network Analysis (GNA), an open-source multivariate tool for performing network analysis using GWAS summary statistics as input. 1/2
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Genomic network analysis characterizes genetic architecture and identifies trait-specific biology
Pervasive genetic overlap across human complex traits necessitates developing multivariate methods that can parse pleiotropic and trait-specific genetic signals. Here, we introduce Genomic Network Ana...
www.medrxiv.org
December 6, 2024 at 3:56 PM
You've heard of DNA, but what about GNA? Very excited about this preprint with @jgthorp.bsky.social and others that introduces Genomic Network Analysis (GNA), an open-source multivariate tool for performing network analysis using GWAS summary statistics as input. 1/2
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Reposted by Andrew Grotzinger
New preprint! www.medrxiv.org/content/10.1...
We introduce Genomic Network Analysis (GNA), a method to conduct network analysis on GWAS sumstats / estimate conditional genetic associations at multiple levels of analysis.
@andrewgrotzinger.bsky.social @zaccyg.bsky.social @drwilliamreay.bsky.social
We introduce Genomic Network Analysis (GNA), a method to conduct network analysis on GWAS sumstats / estimate conditional genetic associations at multiple levels of analysis.
@andrewgrotzinger.bsky.social @zaccyg.bsky.social @drwilliamreay.bsky.social
Genomic network analysis characterizes genetic architecture and identifies trait-specific biology
Pervasive genetic overlap across human complex traits necessitates developing multivariate methods that can parse pleiotropic and trait-specific genetic signals. Here, we introduce Genomic Network Ana...
www.medrxiv.org
December 6, 2024 at 12:50 AM
New preprint! www.medrxiv.org/content/10.1...
We introduce Genomic Network Analysis (GNA), a method to conduct network analysis on GWAS sumstats / estimate conditional genetic associations at multiple levels of analysis.
@andrewgrotzinger.bsky.social @zaccyg.bsky.social @drwilliamreay.bsky.social
We introduce Genomic Network Analysis (GNA), a method to conduct network analysis on GWAS sumstats / estimate conditional genetic associations at multiple levels of analysis.
@andrewgrotzinger.bsky.social @zaccyg.bsky.social @drwilliamreay.bsky.social
Reposted by Andrew Grotzinger
Exciting post-doc position available working on my NIH funded project "Longitudinal multi-omic biomarkers for neurocognitive decline prior to dementia onset". Based in the beautiful city of Edinburgh within @edinunilbc.bsky.social elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
The Lothian Birth Cohorts Group within the Psychology Department, School of Philosophy, Psychology and Language Sciences is seeking a PDRA on a full time, fixed term contract until 30th of June 2025 i...
elxw.fa.em3.oraclecloud.com
December 2, 2024 at 4:54 PM
Exciting post-doc position available working on my NIH funded project "Longitudinal multi-omic biomarkers for neurocognitive decline prior to dementia onset". Based in the beautiful city of Edinburgh within @edinunilbc.bsky.social elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Reposted by Andrew Grotzinger
If you're not following the Behavior Genetics Association account yet (@behaviorgenetic.bsky.social), please do! 🧬🧠🤸🏽
Me and Margot van de Weijer will be running it for the time being, sharing BGA updates and summaries of interesting research from their classic journal 📜
RTs appreciated! 🙏🏽
Me and Margot van de Weijer will be running it for the time being, sharing BGA updates and summaries of interesting research from their classic journal 📜
RTs appreciated! 🙏🏽
October 4, 2024 at 8:33 AM
If you're not following the Behavior Genetics Association account yet (@behaviorgenetic.bsky.social), please do! 🧬🧠🤸🏽
Me and Margot van de Weijer will be running it for the time being, sharing BGA updates and summaries of interesting research from their classic journal 📜
RTs appreciated! 🙏🏽
Me and Margot van de Weijer will be running it for the time being, sharing BGA updates and summaries of interesting research from their classic journal 📜
RTs appreciated! 🙏🏽
🚨Writing to say that I am actively recruiting PhD students in the clinical -or- behavioral, psychiatric, and statistical genetics program (BPSG) at CU Boulder for a Fall 2025 start date. My lab focuses on genomic methods development and applications to psychiatric and aging outcomes (e.g., dementia)
September 23, 2024 at 5:51 PM
🚨Writing to say that I am actively recruiting PhD students in the clinical -or- behavioral, psychiatric, and statistical genetics program (BPSG) at CU Boulder for a Fall 2025 start date. My lab focuses on genomic methods development and applications to psychiatric and aging outcomes (e.g., dementia)
Reposted by Andrew Grotzinger
Examining the Genetic Links between Clusters of Immune-mediated Diseases and Psychiatric Disorders https://www.medrxiv.org/content/10.1101/2024.07.18.24310651v1
Examining the Genetic Links between Clusters of Immune-mediated Diseases and Psychiatric Disorders https://www.medrxiv.org/content/10.1101/2024.07.18.24310651v1
Importance: Autoimmune and autoinflammatory diseases have been linked to psychiatric disorders in th
www.medrxiv.org
July 19, 2024 at 6:40 PM
Examining the Genetic Links between Clusters of Immune-mediated Diseases and Psychiatric Disorders https://www.medrxiv.org/content/10.1101/2024.07.18.24310651v1
Reposted by Andrew Grotzinger
New preprint just dropped! 🧬🦠
For this project, we looked at the genetic relationships between psychiatric disorders and immune-mediated diseases.
Check out the full paper here: www.medrxiv.org/content/10.1...
For this project, we looked at the genetic relationships between psychiatric disorders and immune-mediated diseases.
Check out the full paper here: www.medrxiv.org/content/10.1...
Examining the Genetic Links between Clusters of Immune-mediated Diseases and Psychiatric Disorders
medRxiv - The Preprint Server for Health Sciences
www.medrxiv.org
August 15, 2024 at 4:22 PM
New preprint just dropped! 🧬🦠
For this project, we looked at the genetic relationships between psychiatric disorders and immune-mediated diseases.
Check out the full paper here: www.medrxiv.org/content/10.1...
For this project, we looked at the genetic relationships between psychiatric disorders and immune-mediated diseases.
Check out the full paper here: www.medrxiv.org/content/10.1...
Proud mentor moment! Three preprints recently released from the lab:
1. Postdoc Dr. Isy Foote examined the genetic architecture of frailty. Analyses reveal seven factors of frailty with unique genetic associations, clinical correlates, and biological pathways: www.medrxiv.org/content/10.1...
1. Postdoc Dr. Isy Foote examined the genetic architecture of frailty. Analyses reveal seven factors of frailty with unique genetic associations, clinical correlates, and biological pathways: www.medrxiv.org/content/10.1...
Uncovering the multivariate genetic architecture of frailty with genomic structural equation modelling
medRxiv - The Preprint Server for Health Sciences
www.medrxiv.org
July 25, 2024 at 6:12 PM
Proud mentor moment! Three preprints recently released from the lab:
1. Postdoc Dr. Isy Foote examined the genetic architecture of frailty. Analyses reveal seven factors of frailty with unique genetic associations, clinical correlates, and biological pathways: www.medrxiv.org/content/10.1...
1. Postdoc Dr. Isy Foote examined the genetic architecture of frailty. Analyses reveal seven factors of frailty with unique genetic associations, clinical correlates, and biological pathways: www.medrxiv.org/content/10.1...