Ana Ignatieva
@anaignatieva.bsky.social
Associate Professor of Statistical Genomics (Oxford Stats)
https://www.stats.ox.ac.uk/~ignatiev/
https://www.stats.ox.ac.uk/~ignatiev/
Reposted by Ana Ignatieva
Excited to share a preprint of my PhD project looking at interactions between SNPs and polygenic scores in the UK Biobank!
A thread... 🧵
www.medrxiv.org/content/10.1...
A thread... 🧵
www.medrxiv.org/content/10.1...
Interactions with polygenic background impact quantitative traits in the UK Biobank
Association studies have linked many genetic variants to a variety of phenotypes but under-standing the biological mechanisms underlying these signals remains a major challenge. Since genes operate wi...
www.medrxiv.org
November 24, 2025 at 5:13 PM
Excited to share a preprint of my PhD project looking at interactions between SNPs and polygenic scores in the UK Biobank!
A thread... 🧵
www.medrxiv.org/content/10.1...
A thread... 🧵
www.medrxiv.org/content/10.1...
Reposted by Ana Ignatieva
The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.
October 28, 2025 at 9:31 PM
The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.
Reposted by Ana Ignatieva
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
October 15, 2025 at 3:53 PM
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Reposted by Ana Ignatieva
I’ll be attending #ASHG25! I’m currently hiring for (i) a Senior Research Scientist or (ii) a Postdoc position in my lab. If you’re interested, please reach out to arrange a time to meet and discuss.
October 13, 2025 at 11:19 PM
I’ll be attending #ASHG25! I’m currently hiring for (i) a Senior Research Scientist or (ii) a Postdoc position in my lab. If you’re interested, please reach out to arrange a time to meet and discuss.
Reposted by Ana Ignatieva
Excited to preprint our latest work (w/ Drew DeHaas, Zhibai Jia, Leo Speidel) on using ARGs for demographic inference. w/ applications using data from 1000 Genomes Project. www.biorxiv.org/content/10.1...
Inference of complex demographic history using composite likelihood based on whole-genome genealogies
Accurate parametric inference on complex demographic models is a continuing challenge in population genetics. Ancestral recombination graphs (ARGs) provide richer information than simple population ge...
www.biorxiv.org
October 8, 2025 at 2:48 PM
Excited to preprint our latest work (w/ Drew DeHaas, Zhibai Jia, Leo Speidel) on using ARGs for demographic inference. w/ applications using data from 1000 Genomes Project. www.biorxiv.org/content/10.1...
Delighted that our paper about the distribution of genomic spans of clades/edges in genealogies (ARGs), and using this for detecting inversions and other SVs (and other phenomena that cause local disruption of recombination) is out in MBE academic.oup.com/mbe/article/... (1/n)
The Length of Haplotype Blocks and Signals of Structural Variation in Reconstructed Genealogies
Abstract. Recent breakthroughs have enabled the accurate inference of large-scale genealogies. Through modelling the impact of recombination on the correla
academic.oup.com
October 3, 2025 at 9:54 AM
Delighted that our paper about the distribution of genomic spans of clades/edges in genealogies (ARGs), and using this for detecting inversions and other SVs (and other phenomena that cause local disruption of recombination) is out in MBE academic.oup.com/mbe/article/... (1/n)
Our paper about how ancestral recombination graphs can be used to detect "phantom" genetic interaction signals (that arise due to the genealogy, rather than "real" epistasis) is out in Genetics! Nice thread here by @linoafferreira.bsky.social
academic.oup.com/genetics/adv...
academic.oup.com/genetics/adv...
September 15, 2025 at 10:33 AM
Our paper about how ancestral recombination graphs can be used to detect "phantom" genetic interaction signals (that arise due to the genealogy, rather than "real" epistasis) is out in Genetics! Nice thread here by @linoafferreira.bsky.social
academic.oup.com/genetics/adv...
academic.oup.com/genetics/adv...
Reposted by Ana Ignatieva
📣 We are recruiting! Please share!!
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
July 31, 2025 at 4:12 PM
📣 We are recruiting! Please share!!
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
Are you a bioinformatician / computational scientist who wants to apply your skills to understanding regulatory biology and improving rare disease diagnosis and treatment? 🧠 💻 🧬 🩺
We have two roles available 👇
🧵 1/4
Reposted by Ana Ignatieva
Staff scientist position (computational):
I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record.
#sciencejobs
I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record.
#sciencejobs
July 7, 2025 at 3:27 PM
Staff scientist position (computational):
I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record.
#sciencejobs
I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record.
#sciencejobs
Reposted by Ana Ignatieva
A 4-year postdoc position in population genomics is available in my group at the University of East Anglia, to work on a project sequencing a thousand fox genomes across rural and urban environments in the UK.
vacancies.uea.ac.uk/vacancies/15...
vacancies.uea.ac.uk/vacancies/15...
Senior Research Associate in Population Genomics (RA2327) in University of East Anglia | UEA
View details and apply for this Senior Research Associate in Population Genomics (RA2327) vacancy in University of East Anglia. Faculty of Science
School of Biological Sciences
Senior Research A...
vacancies.uea.ac.uk
June 13, 2025 at 8:46 AM
A 4-year postdoc position in population genomics is available in my group at the University of East Anglia, to work on a project sequencing a thousand fox genomes across rural and urban environments in the UK.
vacancies.uea.ac.uk/vacancies/15...
vacancies.uea.ac.uk/vacancies/15...
Reposted by Ana Ignatieva
Postdoc position in my group in Tokyo!
Please get in touch if you are interested.
And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab.
Job Ad: www.riken.jp/en/careers/r...
Lab page: speidellab.github.io
Please get in touch if you are interested.
And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab.
Job Ad: www.riken.jp/en/careers/r...
Lab page: speidellab.github.io
Seeking a few Postdoctoral Researchers at Mathematical Genomics RIKEN ECL Research Unit (25-695)
www.riken.jp
June 25, 2025 at 5:52 PM
Postdoc position in my group in Tokyo!
Please get in touch if you are interested.
And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab.
Job Ad: www.riken.jp/en/careers/r...
Lab page: speidellab.github.io
Please get in touch if you are interested.
And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab.
Job Ad: www.riken.jp/en/careers/r...
Lab page: speidellab.github.io
Reposted by Ana Ignatieva
Our review of recent Sequentially Markovian Coalescent methods is up on arXiv: arxiv.org/abs/2506.00692 (based on last year's @official-smbe.bsky.social symposium)
Not Just $N_e$ $N_e$-more: New Applications for SMC from Ecology to Phylogenies
Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Ma...
arxiv.org
June 11, 2025 at 5:18 PM
Our review of recent Sequentially Markovian Coalescent methods is up on arXiv: arxiv.org/abs/2506.00692 (based on last year's @official-smbe.bsky.social symposium)
Reposted by Ana Ignatieva
New postdoc positions with a number of exciting epidemic modelling projects opening in our Unit at @pasteur.fr in beautiful Paris. Deadline for applications: 26th June.
research.pasteur.fr/en/job/postd...
research.pasteur.fr/en/job/postd...
Postdoctoral positions in epidemic mathematical/statistical modelling - Research
Job description We are recruiting postdocs to contribute to research projects in the Mathematical Modelling of Infectious Diseases Unit, at Institut Pasteur in Paris. The candidates will be expected t...
research.pasteur.fr
June 5, 2025 at 5:22 AM
New postdoc positions with a number of exciting epidemic modelling projects opening in our Unit at @pasteur.fr in beautiful Paris. Deadline for applications: 26th June.
research.pasteur.fr/en/job/postd...
research.pasteur.fr/en/job/postd...
Reposted by Ana Ignatieva
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
June 1, 2025 at 3:33 PM
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
Reposted by Ana Ignatieva
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @camplantsci.bsky.social
www.jobs.cam.ac.uk/job/51488/
www.jobs.cam.ac.uk/job/51488/
Research Assistant / Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant / Research Associate (Fixed Term) in the Department of Plant Sciences at the University of Cambridge.
www.jobs.cam.ac.uk
May 30, 2025 at 12:13 PM
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @camplantsci.bsky.social
www.jobs.cam.ac.uk/job/51488/
www.jobs.cam.ac.uk/job/51488/
Reposted by Ana Ignatieva
Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition
academic.oup.com/mbe/advance-...
academic.oup.com/mbe/advance-...
Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition
Abstract. A recently proposed model suggests a severe bottleneck in the panmictic ancestral population of modern humans during the Early to Middle Pleistoc
academic.oup.com
February 17, 2025 at 4:56 PM
Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition
academic.oup.com/mbe/advance-...
academic.oup.com/mbe/advance-...
Reposted by Ana Ignatieva
Excited to share a couple of new items (links below):
1. Our work on gene-environment interactions in the UKBiobank is up at the American Journal of Human Genetics
2. Our work on modeling ancient human population size history is up at Molecular Biology and Evolution
1. Our work on gene-environment interactions in the UKBiobank is up at the American Journal of Human Genetics
2. Our work on modeling ancient human population size history is up at Molecular Biology and Evolution
February 17, 2025 at 4:56 PM
Excited to share a couple of new items (links below):
1. Our work on gene-environment interactions in the UKBiobank is up at the American Journal of Human Genetics
2. Our work on modeling ancient human population size history is up at Molecular Biology and Evolution
1. Our work on gene-environment interactions in the UKBiobank is up at the American Journal of Human Genetics
2. Our work on modeling ancient human population size history is up at Molecular Biology and Evolution
Reposted by Ana Ignatieva
Polarizing SNPs without outgroup https://www.biorxiv.org/content/10.1101/2025.01.31.635919v1
February 2, 2025 at 7:31 AM
Polarizing SNPs without outgroup https://www.biorxiv.org/content/10.1101/2025.01.31.635919v1
Reposted by Ana Ignatieva
Excited to share our preprint "A putative ecocline in Klebsiella pneumoniae" and super-interested to get your feedback. Really want to use the hive mind to get to the bottom of this phenomenon ASAP. www.biorxiv.org/content/10.1...
A putative ecocline in Klebsiella pneumoniae
Are quantitative traits important for bacteriology? The quantitative trait models used in animal and plant genetics assume that the trait takes continuous values and is influenced by many variants cir...
www.biorxiv.org
January 27, 2025 at 8:34 AM
Excited to share our preprint "A putative ecocline in Klebsiella pneumoniae" and super-interested to get your feedback. Really want to use the hive mind to get to the bottom of this phenomenon ASAP. www.biorxiv.org/content/10.1...
Reposted by Ana Ignatieva
My bluesky debut!
One week to the submission deadline for SMBE 2025, Beijing 20-24 July smbe2025.scimeeting.cn
@anaignatieva.bsky.social and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.
One week to the submission deadline for SMBE 2025, Beijing 20-24 July smbe2025.scimeeting.cn
@anaignatieva.bsky.social and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.
January 23, 2025 at 12:12 AM
My bluesky debut!
One week to the submission deadline for SMBE 2025, Beijing 20-24 July smbe2025.scimeeting.cn
@anaignatieva.bsky.social and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.
One week to the submission deadline for SMBE 2025, Beijing 20-24 July smbe2025.scimeeting.cn
@anaignatieva.bsky.social and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.
New preprint (with @linoafferreira.bsky.social) where we explore the idea of using genealogies (in the form of ancestral recombination graphs, ARGs) to tell apart real GxG interaction signals between nearby variants from false positives www.biorxiv.org/content/10.1...
Phantom epistasis through the lens of genealogies
Phantom epistasis arises when, in the course of testing for gene-by-gene interactions, the omission of a causal variant (with a purely additive effect on the phenotype) causes the spurious inference o...
www.biorxiv.org
December 9, 2024 at 6:59 PM
New preprint (with @linoafferreira.bsky.social) where we explore the idea of using genealogies (in the form of ancestral recombination graphs, ARGs) to tell apart real GxG interaction signals between nearby variants from false positives www.biorxiv.org/content/10.1...
Reposted by Ana Ignatieva
Very excited (and a bit nervous) to announce that I will be hiring two Postdocs for my new group(!) in Copenhagen to study the Neanderthal and Denisovan DNA which survives in present-day humans. Retweet will be much appreciated :)
Link for application:
candidate.hr-manager.net/ApplicationI...
Link for application:
candidate.hr-manager.net/ApplicationI...
December 2, 2024 at 12:47 PM
Very excited (and a bit nervous) to announce that I will be hiring two Postdocs for my new group(!) in Copenhagen to study the Neanderthal and Denisovan DNA which survives in present-day humans. Retweet will be much appreciated :)
Link for application:
candidate.hr-manager.net/ApplicationI...
Link for application:
candidate.hr-manager.net/ApplicationI...
Reposted by Ana Ignatieva
🎇A brand-new CDT: the Fundamentals of AI, has been launched!🚀
Applications are being accepted for 2025/26.
There are 20 places available, with full funding for home and overseas candidates.
⏳Deadline: 08.01.2025
For more info, visit: dtc.ox.ac.uk/foai-cdt
#eraofAI #AI #CDT #AIforhumanity
Applications are being accepted for 2025/26.
There are 20 places available, with full funding for home and overseas candidates.
⏳Deadline: 08.01.2025
For more info, visit: dtc.ox.ac.uk/foai-cdt
#eraofAI #AI #CDT #AIforhumanity
November 21, 2024 at 11:06 AM
🎇A brand-new CDT: the Fundamentals of AI, has been launched!🚀
Applications are being accepted for 2025/26.
There are 20 places available, with full funding for home and overseas candidates.
⏳Deadline: 08.01.2025
For more info, visit: dtc.ox.ac.uk/foai-cdt
#eraofAI #AI #CDT #AIforhumanity
Applications are being accepted for 2025/26.
There are 20 places available, with full funding for home and overseas candidates.
⏳Deadline: 08.01.2025
For more info, visit: dtc.ox.ac.uk/foai-cdt
#eraofAI #AI #CDT #AIforhumanity
Reposted by Ana Ignatieva
We have 2 Florence Nightingale Bicentenary Fellow positions now open for applications!
🏢 ID: 176627
📍 Dept. of Stats
📃 Contract: FT, 3yrs
💷 Salary Range: £48.2K - £57.2K/yr
⏲️ Deadline: 06.01.25 12pm UK
💼 Interview: 27.01.2025
🔗 URL: my.corehr.com/pls/uoxrecru...
🏢 ID: 176627
📍 Dept. of Stats
📃 Contract: FT, 3yrs
💷 Salary Range: £48.2K - £57.2K/yr
⏲️ Deadline: 06.01.25 12pm UK
💼 Interview: 27.01.2025
🔗 URL: my.corehr.com/pls/uoxrecru...
November 25, 2024 at 12:49 PM
We have 2 Florence Nightingale Bicentenary Fellow positions now open for applications!
🏢 ID: 176627
📍 Dept. of Stats
📃 Contract: FT, 3yrs
💷 Salary Range: £48.2K - £57.2K/yr
⏲️ Deadline: 06.01.25 12pm UK
💼 Interview: 27.01.2025
🔗 URL: my.corehr.com/pls/uoxrecru...
🏢 ID: 176627
📍 Dept. of Stats
📃 Contract: FT, 3yrs
💷 Salary Range: £48.2K - £57.2K/yr
⏲️ Deadline: 06.01.25 12pm UK
💼 Interview: 27.01.2025
🔗 URL: my.corehr.com/pls/uoxrecru...
Reposted by Ana Ignatieva
Postdoc (2.5 years) in population genetics of the Paleolithic in my group. Please apply before January 15. It is an interdisciplinary project with Felix Riede @felixthehauskat.bsky.social, and a new postdoc in his group covering archaeology. Apply through: tinyurl.com/4jt4dru4
Postdoctoral position in population genomics of the palaeolithic - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - BiRC - Bioinformatics Research Center, Aarhus University
tinyurl.com
November 25, 2024 at 10:01 PM
Postdoc (2.5 years) in population genetics of the Paleolithic in my group. Please apply before January 15. It is an interdisciplinary project with Felix Riede @felixthehauskat.bsky.social, and a new postdoc in his group covering archaeology. Apply through: tinyurl.com/4jt4dru4