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aligningscience.com
Coalition for Aligning Science
@aligningscience.com
The Coalition for Aligning Science (CAS) designs and implements large-scale research programs that address unmet needs and maximize impact in biomedical research.
www.aligningscience.com
Explore the Discover ASAP video series! Featuring ASAP grantees, each episode takes a deeper look at datasets, code, protocols, and lab materials, being developed and used to spark new discoveries in #ParkinsonsDisease 🧪

www.youtube.com/playlist?lis...
This month's Discover ASAP features Anastasia Filimontseva of CRN Team Vila 🧪

She shares a new deep learning–enabled platform for automated, standardized quantification of neuromelanin, unlocking faster, more precise insights into pigmented neuron loss in #Parkinsons.

📺 Watch: bit.ly/4jDTOuW
February 3, 2026 at 5:24 PM
Congratulations to the University of Lagos College of Medicine on the opening of their new DNA extraction facility! We’re thrilled that CAS CEO Ekemini Riley joined the celebration to share our excitement and appreciation for this incredible new research and training opportunity.
ASAP and GP2 team members joined researchers and students from the University of Lagos College of Medicine for the opening of a new DNA extraction facility. This GP2-supported lab will house and process samples for submission to GP2 and train researchers, boosting regional research capacity🧬
January 23, 2026 at 4:29 PM
Check out the @bipolardiscoveries.org 2025 Milestone Report 🥼

The BD² network continues to push scientific discovery forward and strengthen collaboration across their global bipolar research community. Explore this year’s progress and what’s ahead in the new year!
We're closing out 2025 with momentum: Our milestone report captures major scientific advances across BD² programs—and the growing global community driving the work 🧪

Explore the progress shaping the future of #BipolarDisorder research.

🔗 bit.ly/496yqL7

#MentalHealth #OpenScience
December 31, 2025 at 11:32 PM
@asapresearch.parkinsonsroadmap.org is driving meaningful momentum in Parkinson’s research 🧪

We are proud to manage an initiative that focuses on accelerating discovery for #Parkinson'sDisease research by fostering a collaborative and open approach for sharing findings and resources.
We’re working with the Michael J. Fox Foundation to shift the #Parkinson’s timeline 🔬

This year, PPMI lowered its screening age to 40 to assess early disease stages.

Learn more through our 2025 #AnnualReport: bit.ly/48OZtcw
December 22, 2025 at 3:04 PM
Follow @wastewaterscan.bsky.social to see how they turn weekly wastewater samples into public health data, tracking trends in infectious diseases.

Plus, check out their new #MeetThePathogens series to learn about the pathogens they monitor nationwide, 365 days a year 🦠
Meet the Pathogen: RSV (Respiratory Syncytial Virus)

RSV spreads through air droplets or by direct contact—lurking on surfaces for hours. Most common in winter and early spring, RSV can be especially serious for infants and older adults.

wastewaterscan.org/en/pathogens#RSV
#MeetThePathogens
December 16, 2025 at 5:51 PM
103,738 🎉
That's the number of samples GP2 has officially collected and genotyped from people all over the world! Watch the video below to see the impact this milestone is poised to have on the future of #ParkinsonsDisease research 👇👇
“For the first time, we have the power to answer questions that we could not address.”

Thanks to 100k+ genotyped samples, the Global Parkinson's Genetics Program is accelerating discovery toward targeted #Parkinsons therapies.

🧪 bit.ly/4pCpSkI
December 3, 2025 at 6:01 PM
Welcome to the CAS team, our newest Associate Program Officer, Dr. Michael Mykins!

Dr. Mykins brings expertise in computational neuroscience to several CAS workstreams, enhancing data management and streamlining operations across our initiatives.

#MeetOurTeam

aligningscience.com/our-team/
November 20, 2025 at 5:51 PM
#MeetOurTeam! We're thrilled to welcome Dr. Shelby Johnson, Program Officer at CAS 🎉

Her expertise in #neuroscience will help support the Aligning Research to Impact Autism initiative in advancing scientific discovery.

aligningscience.com/our-team/
November 12, 2025 at 4:25 PM
We're proud to celebrate the launch of @asapresearch.parkinsonsroadmap.org's new Collaborative Research Network (CRN) website 🧪

Open science is a foundational principle across all ASAP programs, including the CRN, and we are excited to share more about this network!
The Collaborative Research Network has a new home! Explore the new CRN website, a designated space to discover research teams, working groups, and impact highlights driving discovery in #ParkinsonsDisease 🧪

👉 www.asapcrn.org
November 5, 2025 at 4:08 PM
Reminder! @bipolardiscoveries.org (BD2) is accepting Letters of Intent for their Discovery Research funding to advance studies on the biology of bipolar disorder.

LOIs are due November 21.

Watch their webinar to catch up on key details 🧪
youtube.com/watch?v=VNSU5QDumTI
October 29, 2025 at 5:27 PM
Sharing scientific discoveries with the community enables informed decision making.

@wastewaterscan.bsky.social openly shares wastewater monitoring data on infectious diseases to help communities respond with better information and earlier action. #OpenScience

🔎 data.wastewaterscan.org
How do we use #wastewater to monitor infectious diseases like #influenza and #RSV?

📅 Wastewater treatment plants send samples to our lab partner weekly
🧪 Samples are tested for a dozen infectious diseases
📊 Results are posted on our #data dashboard

View the data. data.wastewaterscan.org
October 9, 2025 at 6:21 PM
We are #hiring a Clinical Data Program Officer to lead data strategy for our Aligning Research to Impact Autism (ARIA) Initiative. This is a unique opportunity to shape the future of clinical research while driving innovation and collaboration across institutions 🧪

docs.google.com/document/d/1...
October 6, 2025 at 4:17 PM
Listen to the latest episode of #TheGeneticsPodcast to learn more about how GP2 is setting a new standard in genetic research—bringing in underrepresented populations to strengthen data, deepen insights, and create a roadmap for global collaboration that others can follow 🧪
GP2 joined Patrick Short, PhD, on #TheGeneticsPodcast to discuss their publication in @ajhgnews.bsky.social, noting the scientific importance of diversifying genetic representation in #ParkinsonsResearch and how GP2 empowers scientists worldwide to lead research locally 🧪

🎧 bit.ly/4mHbCFp
October 2, 2025 at 4:55 PM
Big news from BD²: up to $4.5M in funding per team is now open to support #BipolarDisorder discovery research.

Apply here 👉 bit.ly/4mtZ6tC
🚨We’re investing up to $18M in Discovery Research, dedicated to uncovering the biological mechanisms of #BipolarDisorder.

🔬 Up to $1.5M/year for 3 years per team

🧑‍💻 Applicant webinar Oct 8

📅 LOIs due Nov 21

Hear from Daniel Pham, Program Director, on what’s ahead + how to apply: bit.ly/4mtZ6tC 🧠📈
September 23, 2025 at 10:51 PM
We want to build a culture where science is open to all. That's why we’re excited to continue celebrating @alleninstitute.org’s 6th annual #OpenScienceWeek!
Join us in the comments by sharing how open science impacts your work or highlight people and projects making waves in the open science world 🧪
September 17, 2025 at 5:17 PM
WastewaterSCAN: Initiative Spotlight 🔦
@wastewaterscan.bsky.social goal? To show that a national wastewater monitoring system is valuable to public health infrastructure, informs public health responses, and helps us prepare for future pandemics💧
See their dashboard in action: bit.ly/wwscandashboard
September 4, 2025 at 3:05 PM
Breakthrough Discoveries for Thriving With Bipolar Disorder (BD²): Initiative Spotlight 🔦

@bipolardiscoveries.org provides access to breakthrough insights on #bipolar disorder through four unique programs designed to share research with the research community! #OpenScience

bipolardiscoveries.org/
August 27, 2025 at 7:26 PM
Check out a new publication in the American Journal of Human Genetics authored by GP2-associated researchers, including CAS' very own Ekemini Riley, Sonya Dumanis, and Cornelis Blauwendraat!
⬇️
Published today in @geneticssociety.bsky.social's American Journal of Human Genetics: GP2 leaders and researchers explore the need for genetic diversity in #ParkinsonsResearch, the discoveries the GP2 model made possible, and how GP2 is bolstering Parkinson's research worldwide.

🧪 bit.ly/3UACR97
August 20, 2025 at 2:46 PM
Meet Dr. Ellen Guss, our new Program Officer! She supports our ARIA initiative at CAS, bringing deep experience in open science and brain health research. We’re thrilled to have her on board.
#MeetOurTeam

Learn more: www.aligningscience.com/team/ellen-g...
August 13, 2025 at 5:17 PM
We're kicking off our new series: Initiative Spotlight 🔦 starting with Aligning Science Across Parkinson's (ASAP)!

@asapresearch.parkinsonsroadmap.org aims to speed discovery and drive progress toward a #ParkinsonsDisease cure through collaboration and open science.

Learn more: bit.ly/3Ys7sIo
August 7, 2025 at 3:40 PM
Check out a new article detailing how the @asapresearch.parkinsonsroadmap.org and @alleninstitute.org collaboration is driving #neurodegeneration research forward!

Read about CAS founder and CEO Ekemini Riley and COO Sonya Dumanis and their instrumental work in the ASAP initiative! bit.ly/3H8PYLu
Needed ASAP: The Partnership Rewiring Neurodegeneration Research
Aligning Science Across Parkinson’s (ASAP) and the Allen Institute will examine neurodegenerative disease copathologies to develop precision medicines.
bit.ly
August 5, 2025 at 5:18 PM
Our initiative, Aligning Research to Impact Autism, awarded three grants focused on neurosensing and neuromodulation 🎉

Congratulations:
UCSF Weill Institute for Neurosciences
Yale School of Medicine
Stanford Medicine

Learn more about the teams and their work:
ariaroadmap.org/research-roa...
July 31, 2025 at 2:54 PM
Our initiative, Aligning Research to Impact #Autism (ARIA), is launching Frontier Science Hubs to transform autism #research across 5 bold areas: genetics, protein networks, brain circuits, communication, and development 🧪

Learn more about the 5 research areas:
ariaroadmap.org/research-roa...
July 24, 2025 at 3:50 PM
A big step in brain research 🧪

Our initiative Aligning Science Across Parkinson's CRN Cloud and the @alleninstitute.org's Brain Cell Atlas are now connected! This collaborative tool will give researchers a shared foundation to better understand #neurodegenerative diseases like #Parkinsons
July 16, 2025 at 4:07 PM
The Global Parkinson's Genetics Program (GP2), a resource program of the @asapresearch.parkinsonsroadmap.org initiative focused on the genetic architecture of #ParkinsonsDisease, just released its new data release!

Check it out below ⬇️
🔔 GP2’s 10th data release is live on the cohort dashboard!

It includes a new family file and data discovery report with pairwise kinship estimates, capturing both inferred and reported relationships.

🧪 Learn more: gp2.org/the-components-of-gp2s-10th-data-release/
July 9, 2025 at 2:52 PM