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bipolardiscoveries.org
BD²
@bipolardiscoveries.org
560 followers 74 following 130 posts
BD² is a collective force shortening the time it takes to get from scientific breakthroughs to improved clinical care for bipolar disorder.

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BD² @bipolardiscoveries.org · 14d
We're closing out 2025 with momentum: Our milestone report captures major scientific advances across BD² programs—and the growing global community driving the work 🧪

Explore the progress shaping the future of #BipolarDisorder research.

🔗 bit.ly/496yqL7

#MentalHealth #OpenScience
bipolardiscoveries.org
What did BD² achieve in 2025?

New data. Deeper partnerships. Global collaboration 🧪

Dive into our 2025 Milestone Report today!

🔗 bit.ly/496yqL7

#BipolarDisorder #Neuroscience #OpenScience #Research
Blue textured graphic with the BD² logo in the top lefthand corner reading "2025 Milestone Report."
December 18, 2025 at 3:10 PM
bipolardiscoveries.org
We're closing out 2025 with momentum: Our milestone report captures major scientific advances across BD² programs—and the growing global community driving the work 🧪

Explore the progress shaping the future of #BipolarDisorder research.

🔗 bit.ly/496yqL7

#MentalHealth #OpenScience
December 12, 2025 at 6:51 PM
bipolardiscoveries.org
🧪 Research Spotlight: @ignaciosaezphd.bsky.social of the Icahn School of Medicine at Mount Sinai will study brain activity in people with #BipolarDisorder during manic & depressive shifts

👉 Goal: Identify patterns that could guide new treatments with targeted brain stimulation.

🔗 bit.ly/4gTbBwU
A horizontal graphic with a dark blue panel on the lefthand side reading “Discovery Research Grantee ’25; Icahn School of Medicine at Mount Sinai; Research: Intracranial Neurophenotyping of State Switches in Bipolar Disorder.” The right side of the graphic features headshots and titles of the research team: Lead Principal Investigator Ignacio Saez, PhD; and Co-Principal Investigators James Murrough, MD, PhD; Helen Mayberg, MD; and Angela Radulescu, PhD. The BD² logo appears in the bottom lefthand corner.
December 3, 2025 at 3:00 PM
bipolardiscoveries.org
On An Hour To Give, @dr-altimusprime.bsky.social and Jess Fiedorowicz, MD, PhD, join host Sam Laprade to share how BD² and @ottawahospital.on.ca are advancing scientific understanding so that all people with bipolar disorder can lead thriving lives.

📺: bit.ly/4o6dwQE

Read highlights👇
A studio photo of three people seated behind a news-style desk on the set of An Hour to Give. The host, Sam Laprade, CFRE, sits on the left holding papers, with two guests, Cara Altimus, PhD, and Jess Fiedorowicz, MD, PhD, smiling beside her. A screen behind them displays the show’s logo, and the BD² banner reading “BD² on An Hour to Give: Advancing Care Through Collaboration” appears along the bottom. A blue graphic featuring a large quotation mark icon and a pull quote about collaboration in bipolar disorder research. On the right side is a circular headshot of Cara Altimus, PhD, smiling. Her name and title, BD² Managing Director, appear beneath the quote. A blue graphic with a quotation mark icon and a pull quote describing the five-year longitudinal cohort study within the BD² Integrated Network. On the right side is a circular headshot of Jess Fiedorowicz, MD, PhD, smiling. His name and title, Lead Principal Investigator at the Ottawa Hospital Research Institute, appear below the quote. A blue graphic with a large quotation mark icon and a pull quote about the importance of recognizing mental health as health. On the right is a circular headshot of Sam Laprade, CFRE, smiling. Her name and title, Host of An Hour to Give, are shown beneath the quote.
November 21, 2025 at 3:19 PM
bipolardiscoveries.org
🧪 Research Spotlight: Ziad Nahas, MD, MSCR, is studying how brain networks regulate mood in #BipolarDisorder & how instability drives shifts between depression & mania with PACE

👉 Goal: Test if targeting networks can improve mood & reveal mechanisms behind switches.

🔗 bit.ly/4gTbBwU
A horizontal graphic with a teal panel on the lefthand side reading “Discovery Research Grantee ’25; University of Minnesota Medical School; Research: Precision Functional Mapping-Guided Network Stimulation for Bipolar Depression.” The right side of the graphic features headshots and titles of the research team: Lead Principal Investigator Ziad Nahas, MD, MSCR; and Co-Principal Investigators Damien Fair, PA-C, PhD; David Darrow, MD, MPH; Tay Netoff, PhD; and Alex Opitz, PhD. The BD² logo appears in the bottom lefthand corner.
November 19, 2025 at 3:31 PM
bipolardiscoveries.org
🚨 Last call!

Letters of intent for BD²’s Discovery Research RFA are due this Thursday, Nov 21.

🔬 Up to $1.5M/year over 3 years
💡 Research focused on the biology of #BipolarDisorder
🔗 Apply today: bit.ly/4mtZ6tC

Join a network driving discovery in bipolar science
Blue graphic with a title reading "Funding Opportunity Now Open" and subtitle "$18 million is available to support bold, multidisciplinary research." A yellow bar in the bottom right says "Apply by Nov. 21" and the BD² logo appears in the bottom left.
November 18, 2025 at 3:02 PM
bipolardiscoveries.org
🧪 Research Spotlight: Charles Lynch, PhD of @weillcornell.bsky.social, with @stanfordmedicine.bsky.social, is mapping mood-related brain circuits & testing how they shift in people with #Bipolar

👉 Goal: Linking brain activity to mood could open the door to precision treatments.

🔗 bit.ly/4gTbBwU
A horizontal graphic with a green panel on the lefthand side reading "Discovery Research Grantee '25; Weill Cornell Medicine; Research: Precision Mapping and Neuromodulation of Fronto-Striatal-Limbic Brain Circuits to Identify Mood Switch Mechanisms in Bipolar Disorder." The right side of the graphic contains headshots and titles of Lead Principal Investigator Charles Lynch, PhD, and Co-Principal Investigators Corey Keller, MD, PhD, Immanuel Elbau, MD, PhD, Amy Kuceyeski, PhD, and Camarin Rolle, PhD. The BD² logo is in the bottom lefthand corner.
November 12, 2025 at 3:10 PM
bipolardiscoveries.org
⏰ Just 2 weeks left to apply!

BD² is investing up to $18M in Discovery Research to uncover the biological mechanisms of #BipolarDisorder.

🔬 Up to $1.5M/year for 3 years

📅 LOIs due Nov 21

🧠 Join a growing network driving progress in bipolar science.
Apply: bit.ly/4mtZ6tC
Blue graphic with a title reading "Funding Opportunity Now Open" and subtitle "$18 million is available to support bold, multidisciplinary research." A yellow bar in the bottom right says "Apply by Nov. 21" and the BD² logo appears in the bottom left.
November 7, 2025 at 3:09 PM
bipolardiscoveries.org
🧪 Research Spotlight: Michael Fox, MD, PhD (@foxmdphd.bsky.social) of Mass General Brigham (@mgbresearch.bsky.social) will map brain circuits driving symptoms in #BipolarDisorder

👉 Goal: Go beyond imaging correlations to identify the circuits causing symptoms.

🔗 bit.ly/4gTbBwU
November 5, 2025 at 3:00 PM
bipolardiscoveries.org
We are proud to award $18M to four new Discovery Research teams exploring neuromodulation and brain circuits in #Bipolar 🧠📈

🔗bit.ly/48M1TKP

🎙️ Hear from Daniel Pham, PhD, and the teams about their innovative projects 👇
October 28, 2025 at 2:20 PM
bipolardiscoveries.org
📺 “The best antidote to stigma is people sharing their own stories.”

Major General Gregg Martin, PhD, joins BD²’s Emily Baxi, PhD, Program Director, to discuss resilience, recovery, and how science and lived experience can change care for #BipolarDisorder.

🔗 Learn more: bit.ly/4nWlnkw
October 22, 2025 at 2:06 PM
bipolardiscoveries.org
🧠📈 TOMORROW: Join BD²’s Daniel Pham, PhD, and Kelsey Barcomb, PhD, for a webinar answering questions on the Cycle 4 Discovery Research RFA—investing up to $18M in #BipolarDisorder research.

💡 Up to $1.5M/yr for 3 years (with possible renewal)
📅 LOIs due Nov 21
🔗 forms.office.com/r/MvBUnTUCbK
Image with the bolded title “Discovery Research RFA Webinar.” A yellow button reading “Register Now” appears on the left, above the event date “October 8 | 12 PM ET.” On the right, two speaker panels show Daniel Pham, PhD, Program Director, Discovery Research, and Kelsey Barcomb, PhD, Program Manager, Discovery Research, each with headshots and titles. The background features a light gray textured pattern.
October 7, 2025 at 2:00 PM
bipolardiscoveries.org
🚨 REMINDER: Next Wednesday, BD²'s Daniel Pham, PhD & Kelsey Barcomb, PhD, are hosting a webinar on the Cycle 4 Discovery Research RFA. They'll review the key information and requirements for your application.

🔗 Register: forms.office.com/r/MvBUnTUCbK
Image with the bolded title “Discovery Research RFA Webinar.” A yellow button reading “Register Now” appears on the left, above the event date “October 8 | 12 PM ET.” On the right, two speaker panels show Daniel Pham, PhD, Program Director, Discovery Research, and Kelsey Barcomb, PhD, Program Manager, Discovery Research, each with headshots and titles. The background features a light gray textured pattern.
October 3, 2025 at 2:00 PM
bipolardiscoveries.org
📢 Next Wednesday (October 8, 12 PM ET), BD² will host a webinar on the Cycle 4 Discovery Research RFA. Daniel Pham, PhD, & Kelsey Barcomb, PhD, will review eligibility, scope, LOI requirements, Open Science expectations, & key dates.

Register now 👉 forms.office.com/r/MvBUnTUCbK
Image with the bolded title “Discovery Research RFA Webinar.” A yellow button reading “Register Now” appears on the left, above the event date “October 8 | 12 PM ET.” On the right, two speaker panels show Daniel Pham, PhD, Program Director, Discovery Research, and Kelsey Barcomb, PhD, Program Manager, Discovery Research, each with headshots and titles. The background features a light gray textured pattern.
October 1, 2025 at 2:00 PM
bipolardiscoveries.org
📢 Exciting update: BD² and CareEvolution have partnered to launch BD² Connect.

This new digital tool supports BD² Integrated Network study participants manage EHRs, sync wearables, and engage in research that aims to improve care for #bipolardisorder.

🔗 Learn more: bit.ly/46lil2Y
Graphic with a blue textured background featuring the headline: “BD² and CareEvolution Partner to Provide New Digital Tool to Support Bipolar Disorder Study Participants.” At the bottom are the CareEvolution and BD² logos, with a yellow button on the left labeled “Learn More.”
September 23, 2025 at 2:02 PM
bipolardiscoveries.org
🌎🧪 Apply for our open Discovery Research grants and join a network of scientists across the world who are dedicated to improving the lives of people with #bipolardisorder.

🔗 Read the RFA: bit.ly/4mtZ6tC
Image of a world map with the bolded title "BD² Discovery Research" and italicized subtitle "Grantee Locations" in the top lefthand corner. Across the map, orange dots symbolize the locations of BD² grantee institutions across the US, Europe, and Australia.
September 17, 2025 at 2:00 PM
bipolardiscoveries.org
🚨We’re investing up to $18M in Discovery Research, dedicated to uncovering the biological mechanisms of #BipolarDisorder.

🔬 Up to $1.5M/year for 3 years per team

🧑‍💻 Applicant webinar Oct 8

📅 LOIs due Nov 21

Hear from Daniel Pham, Program Director, on what’s ahead + how to apply: bit.ly/4mtZ6tC 🧠📈
September 10, 2025 at 2:08 PM
bipolardiscoveries.org
BD² is transforming science, care & outcomes for people with #bipolardisorder. 🧪

Our 2025 Progress Report shows how we’re expanding our network, advancing research & building resources to improve care.

Check out the update: www.bipolardiscoveries.org/2025/08/2025...
Graphic with a blue and teal gradient background featuring a quote from Cara Altimus, PhD. The BD² North Star logo, a circular compass-like design, sits on the lower right side. The quote reads: “In the first half of 2025, we’ve built powerful momentum. Together, we’re making steady, meaningful progress toward a future where everyone with bipolar disorder has the opportunity to thrive.” Beneath the quote, Cara Altimus’ name appears in orange bold text with the title “BD² Managing Director” in white below. On the left side of the quote, a headshot of Cara Altimus is shown.
August 27, 2025 at 2:08 PM
bipolardiscoveries.org
What if #BipolarDisorder care was shaped by those living it—and powered by real-time data? 🧪

Read about how BD² Integrated Network is doing that with insights from Mark Frye, MD, Sam Savitz, PhD, and @ahvinson.bsky.social

bit.ly/477P5xr
Graphic titled “An Interview with BD² Integrated Network Leaders” with subheading “Transforming Bipolar Disorder Research and Treatment.” The image features three headshots: Mark Frye, MD (left), Sam Savitz, PhD (center), and Alexandra Vinson, PhD (right). At the bottom is the BD² logo with the tagline: “Breakthrough Discoveries for thriving with Bipolar Disorder.”
August 21, 2025 at 4:56 PM
bipolardiscoveries.org
BD² leaders @dr-altimusprime.bsky.social, Katherine Burdick, PhD, and Mark Frye, MD, sat down with @morra.bsky.social on the Anxious Achiever Podcast for a conversation about the future of #bipolardisorder research. Tune in ▶️ tinyurl.com/58fxkmxt
Understanding Bipolar Disorder With The Scientists Driving Innovation
The Anxious Achiever · Episode
tinyurl.com
August 13, 2025 at 2:02 PM
bipolardiscoveries.org
🔬 BD² Integrated Network Program Director @emilybaxi.bsky.social recently joined @biorender.bsky.social ‬ on a panel about the state of science funding. Watch as she discusses how BD²’s funding strategically supports its priorities in #bipolardisorder research.
August 5, 2025 at 2:01 PM
bipolardiscoveries.org
🔍 New in @thelancet.com: A Comprehensive Update on #BipolarDisorder

Led by BD² investigator Balwinder Singh, MD, this is a must-read for those working to improve outcomes for individuals with #bipolardisorder.

📖 Read the paper: authors.elsevier.com/a/1lTurV-4XS...

▶️ Hear from Balwinder Singh, MD:
July 29, 2025 at 6:47 PM
bipolardiscoveries.org
A huge congratulations to BD² Investigators Balwinder Singh, MD, and@drsarahsperry.bsky.social, and SSC Chairs Katherine Burdick, PhD, and Mark Frye, MD, on their new Seminar in @thelancet.com—a global review of bipolar disorder diagnosis, treatment, and future directions. Take a look ⬇️
drsarahsperry.bsky.social Dr. Sarah Sperry @drsarahsperry.bsky.social · Jul 23
Check out our new Seminar on bipolar disorder in @thelancet.com! Was wonderful to work with these co-authors, led by Balwinder Singh.

authors.elsevier.com/a/1lTurV-4XS...
authors.elsevier.com
July 24, 2025 at 3:40 PM
bipolardiscoveries.org
🚨 Happening TODAY at 2:00 PM ET (7/23): BD² Integrated Network Program Director @emilybaxi.bsky.social joins fellow scientific leaders for a timely discussion on the state of U.S. science funding.

🔗 Register now: tinyurl.com/3p96dypp
https://tinyurl.com/3p96dypp"
July 23, 2025 at 1:38 PM
bipolardiscoveries.org
ICYMI: We announced our first international Integrated Network site! We are joining forces with @braincanada.bsky.social to support our newest site at @ottawahospital.on.ca. Learn more about this milestone: tinyurl.com/cppm65hj
BD² and Brain Canada Announce Partnership and New International Site to Join Landmark Bipolar Disorder Research Network
Washington, D.C.: Today, Breakthrough Discoveries for thriving with Bipolar Disorder (BD²) and Brain Canada announced an international partnership to advance research and transform care for people liv...
tinyurl.com
July 15, 2025 at 3:37 PM