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bipolardiscoveries.org
BD²
@bipolardiscoveries.org
560 followers 75 following 130 posts
BD² is a collective force shortening the time it takes to get from scientific breakthroughs to improved clinical care for bipolar disorder.

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BD² @bipolardiscoveries.org · Dec 12
We're closing out 2025 with momentum: Our milestone report captures major scientific advances across BD² programs—and the growing global community driving the work 🧪

Explore the progress shaping the future of #BipolarDisorder research.

🔗 bit.ly/496yqL7

#MentalHealth #OpenScience
bipolardiscoveries.org
🎥 Video courtesy of The Conn Job podcast
February 5, 2026 at 3:00 PM
bipolardiscoveries.org
BD² joined The Conn Job podcast to talk about what’s next for #BipolarDisorder research.

From brain omics and AI to large-scale collaboration, the conversation explores how psychiatry is moving beyond trial-and-error toward a more precise, data-driven future—grounded in hope 🧠📈

🎧: bit.ly/3Mm86En
February 5, 2026 at 3:00 PM
bipolardiscoveries.org
📢 Milestone for bipolar disorder research! The BD² Integrated Network Longitudinal Cohort Protocol is now live: laying the foundation for the largest, most comprehensive prospective study in bipolar disorder and a new model for linking research directly to care. 📄🧪

🔗 bit.ly/451Bg1R
January 27, 2026 at 3:00 PM
bipolardiscoveries.org
Great to be part of the @acnporg.bsky.social Annual Meeting last week!

BD² team members and researchers joined scientists to discuss advances in precision psychiatry and neuroimaging-guided brain targeting.

Proud to connect with partners advancing bipolar disorder research. 📈🧠
#ACNP2026
Five attendees at the ACNP Annual Meeting standing together and smiling: Daniel Pham, Cara Altimus, Sylvie Raver, Brandon Staglin, Emily Baxi, and Tahilia Rebello. The group is gathered in a conference setting. Panel discussion at the ACNP Annual Meeting titled “Neuroimaging-Guided Precision Brain Targeting in Mood Disorders.” Panelists are standing by the stage, including chair Hilary Blumberg (center) and speakers Anjali Sankar, Helen Mayberg, Mary Phillips, and Conor Liston. Conference photo of Daniel Pham, Sylvie Raver, and Emily Baxi standing with researcher Kate Burdick at the ACNP Annual Meeting. Photo of a presentation slide shown during the ACNP President’s Plenary listing ACNP Advocacy Affiliates.
January 21, 2026 at 2:59 PM
bipolardiscoveries.org
@dr-altimusprime.bsky.social @emilybaxi.bsky.social @dpham0.bsky.social @careevolution.com
December 30, 2025 at 1:51 PM
bipolardiscoveries.org
As we close 2025, we’re reflecting on a pivotal year built on years of research, collaboration, and commitment.

We’re thankful to the global BD² community, researchers, clinicians, and participants, whose work continues to drive discovery forward 💙

#BipolarDisorder #MentalHealthResearch
Five panelists sit on stage in armchairs during a discussion at the Milken Institute Asia Summit 2025. A teal backdrop behind them reads “Asia Summit 2025: Progress with Purpose—Collaboration Amid Complexity,” with Milken Institute logos. Large group of adults standing outdoors in front of a multi-story building with balconies and palm trees. The group is arranged in several rows, smiling and waving toward the camera, with many wearing colorful baseball caps. Four people stand smiling and pointing toward a research poster displayed on a conference poster board. The poster is titled “Innovative Mechanisms to Build a Collaborative Community within BD²: Breakthrough Discoveries for Thriving with Bipolar Disorder” and includes diagrams, charts, and text blocks. Three people sit behind a curved glass desk on a television studio set. A screen behind them displays the title “An Hour to Give.” The brick-walled studio includes warm lighting and window backdrops.
December 30, 2025 at 1:49 PM
bipolardiscoveries.org
What did BD² achieve in 2025?

New data. Deeper partnerships. Global collaboration 🧪

Dive into our 2025 Milestone Report today!

🔗 bit.ly/496yqL7

#BipolarDisorder #Neuroscience #OpenScience #Research
Blue textured graphic with the BD² logo in the top lefthand corner reading "2025 Milestone Report."
December 18, 2025 at 3:10 PM
bipolardiscoveries.org
We're closing out 2025 with momentum: Our milestone report captures major scientific advances across BD² programs—and the growing global community driving the work 🧪

Explore the progress shaping the future of #BipolarDisorder research.

🔗 bit.ly/496yqL7

#MentalHealth #OpenScience
December 12, 2025 at 6:51 PM
bipolardiscoveries.org
@sinaibrain.bsky.social @angelaradulescu.bsky.social
December 3, 2025 at 3:00 PM
bipolardiscoveries.org
🧪 Research Spotlight: @ignaciosaezphd.bsky.social of the Icahn School of Medicine at Mount Sinai will study brain activity in people with #BipolarDisorder during manic & depressive shifts

👉 Goal: Identify patterns that could guide new treatments with targeted brain stimulation.

🔗 bit.ly/4gTbBwU
A horizontal graphic with a dark blue panel on the lefthand side reading “Discovery Research Grantee ’25; Icahn School of Medicine at Mount Sinai; Research: Intracranial Neurophenotyping of State Switches in Bipolar Disorder.” The right side of the graphic features headshots and titles of the research team: Lead Principal Investigator Ignacio Saez, PhD; and Co-Principal Investigators James Murrough, MD, PhD; Helen Mayberg, MD; and Angela Radulescu, PhD. The BD² logo appears in the bottom lefthand corner.
December 3, 2025 at 3:00 PM
bipolardiscoveries.org
On An Hour To Give, @dr-altimusprime.bsky.social and Jess Fiedorowicz, MD, PhD, join host Sam Laprade to share how BD² and @ottawahospital.on.ca are advancing scientific understanding so that all people with bipolar disorder can lead thriving lives.

📺: bit.ly/4o6dwQE

Read highlights👇
A studio photo of three people seated behind a news-style desk on the set of An Hour to Give. The host, Sam Laprade, CFRE, sits on the left holding papers, with two guests, Cara Altimus, PhD, and Jess Fiedorowicz, MD, PhD, smiling beside her. A screen behind them displays the show’s logo, and the BD² banner reading “BD² on An Hour to Give: Advancing Care Through Collaboration” appears along the bottom. A blue graphic featuring a large quotation mark icon and a pull quote about collaboration in bipolar disorder research. On the right side is a circular headshot of Cara Altimus, PhD, smiling. Her name and title, BD² Managing Director, appear beneath the quote. A blue graphic with a quotation mark icon and a pull quote describing the five-year longitudinal cohort study within the BD² Integrated Network. On the right side is a circular headshot of Jess Fiedorowicz, MD, PhD, smiling. His name and title, Lead Principal Investigator at the Ottawa Hospital Research Institute, appear below the quote. A blue graphic with a large quotation mark icon and a pull quote about the importance of recognizing mental health as health. On the right is a circular headshot of Sam Laprade, CFRE, smiling. Her name and title, Host of An Hour to Give, are shown beneath the quote.
November 21, 2025 at 3:19 PM
bipolardiscoveries.org
@ziad-nahas.bsky.social @drdamienfair.bsky.social
@drdaviddarrow.bsky.social
November 19, 2025 at 3:39 PM
bipolardiscoveries.org
🧪 Research Spotlight: Ziad Nahas, MD, MSCR, is studying how brain networks regulate mood in #BipolarDisorder & how instability drives shifts between depression & mania with PACE

👉 Goal: Test if targeting networks can improve mood & reveal mechanisms behind switches.

🔗 bit.ly/4gTbBwU
A horizontal graphic with a teal panel on the lefthand side reading “Discovery Research Grantee ’25; University of Minnesota Medical School; Research: Precision Functional Mapping-Guided Network Stimulation for Bipolar Depression.” The right side of the graphic features headshots and titles of the research team: Lead Principal Investigator Ziad Nahas, MD, MSCR; and Co-Principal Investigators Damien Fair, PA-C, PhD; David Darrow, MD, MPH; Tay Netoff, PhD; and Alex Opitz, PhD. The BD² logo appears in the bottom lefthand corner.
November 19, 2025 at 3:31 PM
bipolardiscoveries.org
🚨 Last call!

Letters of intent for BD²’s Discovery Research RFA are due this Thursday, Nov 21.

🔬 Up to $1.5M/year over 3 years
💡 Research focused on the biology of #BipolarDisorder
🔗 Apply today: bit.ly/4mtZ6tC

Join a network driving discovery in bipolar science
Blue graphic with a title reading "Funding Opportunity Now Open" and subtitle "$18 million is available to support bold, multidisciplinary research." A yellow bar in the bottom right says "Apply by Nov. 21" and the BD² logo appears in the bottom left.
November 18, 2025 at 3:02 PM
bipolardiscoveries.org
🧪 Research Spotlight: Charles Lynch, PhD of @weillcornell.bsky.social, with @stanfordmedicine.bsky.social, is mapping mood-related brain circuits & testing how they shift in people with #Bipolar

👉 Goal: Linking brain activity to mood could open the door to precision treatments.

🔗 bit.ly/4gTbBwU
A horizontal graphic with a green panel on the lefthand side reading "Discovery Research Grantee '25; Weill Cornell Medicine; Research: Precision Mapping and Neuromodulation of Fronto-Striatal-Limbic Brain Circuits to Identify Mood Switch Mechanisms in Bipolar Disorder." The right side of the graphic contains headshots and titles of Lead Principal Investigator Charles Lynch, PhD, and Co-Principal Investigators Corey Keller, MD, PhD, Immanuel Elbau, MD, PhD, Amy Kuceyeski, PhD, and Camarin Rolle, PhD. The BD² logo is in the bottom lefthand corner.
November 12, 2025 at 3:10 PM
bipolardiscoveries.org
⏰ Just 2 weeks left to apply!

BD² is investing up to $18M in Discovery Research to uncover the biological mechanisms of #BipolarDisorder.

🔬 Up to $1.5M/year for 3 years

📅 LOIs due Nov 21

🧠 Join a growing network driving progress in bipolar science.
Apply: bit.ly/4mtZ6tC
Blue graphic with a title reading "Funding Opportunity Now Open" and subtitle "$18 million is available to support bold, multidisciplinary research." A yellow bar in the bottom right says "Apply by Nov. 21" and the BD² logo appears in the bottom left.
November 7, 2025 at 3:09 PM
bipolardiscoveries.org
🧪 Research Spotlight: Michael Fox, MD, PhD (@foxmdphd.bsky.social) of Mass General Brigham (@mgbresearch.bsky.social) will map brain circuits driving symptoms in #BipolarDisorder

👉 Goal: Go beyond imaging correlations to identify the circuits causing symptoms.

🔗 bit.ly/4gTbBwU
November 5, 2025 at 3:00 PM
bipolardiscoveries.org
We’re proud to support you and your team.

Your work is helping chart new territory in understanding, and ultimately treating, the brain’s most complex circuits.
October 30, 2025 at 5:58 PM
bipolardiscoveries.org
The next cycle of funding for BD²’s Discovery Research program is now open! Up to $18M is available, which offers $1.5M per year for 3 years to advance bold, collaborative studies uncovering the biology of #Bipolar. LOIs due Nov 21 👉 bit.ly/4mtZ6tC
October 28, 2025 at 2:22 PM
bipolardiscoveries.org
We are proud to award $18M to four new Discovery Research teams exploring neuromodulation and brain circuits in #Bipolar 🧠📈

🔗bit.ly/48M1TKP

🎙️ Hear from Daniel Pham, PhD, and the teams about their innovative projects 👇
October 28, 2025 at 2:20 PM
bipolardiscoveries.org
📺 “The best antidote to stigma is people sharing their own stories.”

Major General Gregg Martin, PhD, joins BD²’s Emily Baxi, PhD, Program Director, to discuss resilience, recovery, and how science and lived experience can change care for #BipolarDisorder.

🔗 Learn more: bit.ly/4nWlnkw
October 22, 2025 at 2:06 PM
bipolardiscoveries.org
🧠📈 TOMORROW: Join BD²’s Daniel Pham, PhD, and Kelsey Barcomb, PhD, for a webinar answering questions on the Cycle 4 Discovery Research RFA—investing up to $18M in #BipolarDisorder research.

💡 Up to $1.5M/yr for 3 years (with possible renewal)
📅 LOIs due Nov 21
🔗 forms.office.com/r/MvBUnTUCbK
Image with the bolded title “Discovery Research RFA Webinar.” A yellow button reading “Register Now” appears on the left, above the event date “October 8 | 12 PM ET.” On the right, two speaker panels show Daniel Pham, PhD, Program Director, Discovery Research, and Kelsey Barcomb, PhD, Program Manager, Discovery Research, each with headshots and titles. The background features a light gray textured pattern.
October 7, 2025 at 2:00 PM
bipolardiscoveries.org
🚨 REMINDER: Next Wednesday, BD²'s Daniel Pham, PhD & Kelsey Barcomb, PhD, are hosting a webinar on the Cycle 4 Discovery Research RFA. They'll review the key information and requirements for your application.

🔗 Register: forms.office.com/r/MvBUnTUCbK
Image with the bolded title “Discovery Research RFA Webinar.” A yellow button reading “Register Now” appears on the left, above the event date “October 8 | 12 PM ET.” On the right, two speaker panels show Daniel Pham, PhD, Program Director, Discovery Research, and Kelsey Barcomb, PhD, Program Manager, Discovery Research, each with headshots and titles. The background features a light gray textured pattern.
October 3, 2025 at 2:00 PM
bipolardiscoveries.org
📢 Next Wednesday (October 8, 12 PM ET), BD² will host a webinar on the Cycle 4 Discovery Research RFA. Daniel Pham, PhD, & Kelsey Barcomb, PhD, will review eligibility, scope, LOI requirements, Open Science expectations, & key dates.

Register now 👉 forms.office.com/r/MvBUnTUCbK
Image with the bolded title “Discovery Research RFA Webinar.” A yellow button reading “Register Now” appears on the left, above the event date “October 8 | 12 PM ET.” On the right, two speaker panels show Daniel Pham, PhD, Program Director, Discovery Research, and Kelsey Barcomb, PhD, Program Manager, Discovery Research, each with headshots and titles. The background features a light gray textured pattern.
October 1, 2025 at 2:00 PM
bipolardiscoveries.org
📢 Exciting update: BD² and CareEvolution have partnered to launch BD² Connect.

This new digital tool supports BD² Integrated Network study participants manage EHRs, sync wearables, and engage in research that aims to improve care for #bipolardisorder.

🔗 Learn more: bit.ly/46lil2Y
Graphic with a blue textured background featuring the headline: “BD² and CareEvolution Partner to Provide New Digital Tool to Support Bipolar Disorder Study Participants.” At the bottom are the CareEvolution and BD² logos, with a yellow button on the left labeled “Learn More.”
September 23, 2025 at 2:02 PM