Alfie Wearn
@alfiewearn.bsky.social
Postdoc Fellow at The Montreal Neurological Institute 🧠 | Structural Neuroimaging of Alzheimer's disease | OHBM Communications Committee @ohbm-com.com | He/Him
We just published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo.
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
November 9, 2025 at 5:00 PM
We just published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo.
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
Reposted by Alfie Wearn
The search for early signs of Alzheimer's disease continues: Brain scans reveal microstructural changes in the hippocampus that signal early stages of the disease, including demyelination, increased iron deposition, and changes in water content. In PNAS: https://ow.ly/1NvV50XkXnX
October 31, 2025 at 4:03 PM
The search for early signs of Alzheimer's disease continues: Brain scans reveal microstructural changes in the hippocampus that signal early stages of the disease, including demyelination, increased iron deposition, and changes in water content. In PNAS: https://ow.ly/1NvV50XkXnX
Reposted by Alfie Wearn
HippoMaps: an open-source resource for studying the human hippocampus at different scales and with different modalities.
www.nature.com/articles/s41...
@jordandekraker.bsky.social @borismontreal.bsky.social @jclauneuro.bsky.social @neuroak.bsky.social @sofievalk.bsky.social @donnagift.bsky.social
www.nature.com/articles/s41...
@jordandekraker.bsky.social @borismontreal.bsky.social @jclauneuro.bsky.social @neuroak.bsky.social @sofievalk.bsky.social @donnagift.bsky.social
HippoMaps: multiscale cartography of human hippocampal organization - Nature Methods
HippoMaps provides an open-source resource for studying the human hippocampus at different scales and with different modalities such as histology, fMRI, structural MRI and EEG.
www.nature.com
October 3, 2025 at 12:50 PM
HippoMaps: an open-source resource for studying the human hippocampus at different scales and with different modalities.
www.nature.com/articles/s41...
@jordandekraker.bsky.social @borismontreal.bsky.social @jclauneuro.bsky.social @neuroak.bsky.social @sofievalk.bsky.social @donnagift.bsky.social
www.nature.com/articles/s41...
@jordandekraker.bsky.social @borismontreal.bsky.social @jclauneuro.bsky.social @neuroak.bsky.social @sofievalk.bsky.social @donnagift.bsky.social
Reposted by Alfie Wearn
Healthy scientific communities—built on open, engaged communication—are ready to take on the next challenges facing broader society.
Had a blast writing this piece with @dupre.science and @alfiewearn.bsky.social. Many thanks to the other past @ohbm-com.com chairs for their feedback and support!
Had a blast writing this piece with @dupre.science and @alfiewearn.bsky.social. Many thanks to the other past @ohbm-com.com chairs for their feedback and support!
Kicking off the Future of Scientific Publishing Special Issue, former @ohbm-com.com Chairs highlight the importance of effective science communication: doi.org/10.52294/001...
@sitek.bsky.social @alfiewearn.bsky.social @dupre.science @ohbmofficial.bsky.social
@sitek.bsky.social @alfiewearn.bsky.social @dupre.science @ohbmofficial.bsky.social
September 16, 2025 at 7:31 PM
Healthy scientific communities—built on open, engaged communication—are ready to take on the next challenges facing broader society.
Had a blast writing this piece with @dupre.science and @alfiewearn.bsky.social. Many thanks to the other past @ohbm-com.com chairs for their feedback and support!
Had a blast writing this piece with @dupre.science and @alfiewearn.bsky.social. Many thanks to the other past @ohbm-com.com chairs for their feedback and support!
Reposted by Alfie Wearn
Our award-winning news team is looking for an enthusiastic trade journalist to join our fast-paced newsroom in NYC. This is an excellent opportunity for a science journalist to develop a beat in the field of neuroscience. For more info, please visit: bit.ly/4nvAy4k
#neuroskyence
#neuroskyence
Reporter, The Transmitter
The Transmitter offers up-to-date news and analysis of the field of neuroscience and is dedicated to helping scientists at all career stages stay current and build connections. Our award-winning news ...
simonsfoundation.wd1.myworkdayjobs.com
July 2, 2025 at 4:04 PM
Our award-winning news team is looking for an enthusiastic trade journalist to join our fast-paced newsroom in NYC. This is an excellent opportunity for a science journalist to develop a beat in the field of neuroscience. For more info, please visit: bit.ly/4nvAy4k
#neuroskyence
#neuroskyence
Reposted by Alfie Wearn
In @ohbmossig.bsky.social's first Open Datasets Special Issue paper, Wearn et al. introduce the OHBM Time Machine, a freely accessible archive of Annual Meeting content on YouTube: doi.org/10.52294/001...
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
June 27, 2025 at 7:23 AM
In @ohbmossig.bsky.social's first Open Datasets Special Issue paper, Wearn et al. introduce the OHBM Time Machine, a freely accessible archive of Annual Meeting content on YouTube: doi.org/10.52294/001...
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
#OHBM2025 !
Let's chat about how noradrenergic system health influences brain network segregation.
Poster #0916 today and tomorrow (Wed-Thurs)
See you there this afternoon!
Let's chat about how noradrenergic system health influences brain network segregation.
Poster #0916 today and tomorrow (Wed-Thurs)
See you there this afternoon!
June 25, 2025 at 1:43 AM
#OHBM2025 !
Let's chat about how noradrenergic system health influences brain network segregation.
Poster #0916 today and tomorrow (Wed-Thurs)
See you there this afternoon!
Let's chat about how noradrenergic system health influences brain network segregation.
Poster #0916 today and tomorrow (Wed-Thurs)
See you there this afternoon!
Reposted by Alfie Wearn
Last chance to sign up to a Communications Competition at #OHBM2025!
Choose from:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/HE8GUxWyYS4o...
Choose from:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/HE8GUxWyYS4o...
forms.gle
June 13, 2025 at 12:32 PM
Last chance to sign up to a Communications Competition at #OHBM2025!
Choose from:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/HE8GUxWyYS4o...
Choose from:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/HE8GUxWyYS4o...
Reposted by Alfie Wearn
My laboratory at Université Laval in Québec City, Canada, is looking for a postdoc to study how neuromodulatory systems impact cortical processing during foraging behavior. This fully-funded position offers a collaborative environment in a great city. More info👇
can-acn.org/postdoctoral...
can-acn.org/postdoctoral...
Postdoctoral position available in the Breton-Provencher Lab at Université Laval to study neuromodulatory systems and foraging behavior – Canadian Association for Neuroscience
can-acn.org
June 2, 2025 at 2:59 PM
My laboratory at Université Laval in Québec City, Canada, is looking for a postdoc to study how neuromodulatory systems impact cortical processing during foraging behavior. This fully-funded position offers a collaborative environment in a great city. More info👇
can-acn.org/postdoctoral...
can-acn.org/postdoctoral...
Reposted by Alfie Wearn
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
May 23, 2025 at 5:56 PM
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
Reposted by Alfie Wearn
Going to #OHBM2025 in Brisbane?
We're accepting entries for *two in-person science communication competitions* at the annual meeting:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/1X9ccz2vpsRQ...
We're accepting entries for *two in-person science communication competitions* at the annual meeting:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/1X9ccz2vpsRQ...
forms.gle
May 12, 2025 at 2:26 PM
Going to #OHBM2025 in Brisbane?
We're accepting entries for *two in-person science communication competitions* at the annual meeting:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/1X9ccz2vpsRQ...
We're accepting entries for *two in-person science communication competitions* at the annual meeting:
📊 A Best Figure Competition
🗣️ 3-Minute Chalk Talk Competition
⭐ See here for more details, or to sign up for one or both competitions:
forms.gle/1X9ccz2vpsRQ...
Reposted by Alfie Wearn
I have an opening for a graduate student at @carleton.ca (Carleton University) in the Department of Cognitive Science for fall 2025. Project is a multimodal MRI study examining how Hearing Loss affects cognition in older adults - contact me with a CV if you’re interested & have relevant expertise!
April 4, 2025 at 10:33 PM
I have an opening for a graduate student at @carleton.ca (Carleton University) in the Department of Cognitive Science for fall 2025. Project is a multimodal MRI study examining how Hearing Loss affects cognition in older adults - contact me with a CV if you’re interested & have relevant expertise!
Reposted by Alfie Wearn
There's a stream of excellent papers in @apertureohbm.bsky.social being published!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
March 22, 2025 at 2:28 PM
There's a stream of excellent papers in @apertureohbm.bsky.social being published!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
Reposted by Alfie Wearn
There are days in life that shake you.
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
March 18, 2025 at 11:27 PM
There are days in life that shake you.
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
I was privileged to collaborate with the brilliant Stéfanie Tremblay on her project, just published in Neurobiology of Aging:
Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease
bit.ly/3Rb3QWW
Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease
bit.ly/3Rb3QWW
Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease
Early detection of pathological changes in Alzheimer's disease (AD) has garnered significant attention in the last few decades as interventions aiming…
bit.ly
March 16, 2025 at 4:25 PM
I was privileged to collaborate with the brilliant Stéfanie Tremblay on her project, just published in Neurobiology of Aging:
Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease
bit.ly/3Rb3QWW
Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease
bit.ly/3Rb3QWW
Reposted by Alfie Wearn
Anyone know if neuroscientists stopped doing this www.theguardian.com/commentisfre...
The statistical error that just keeps on coming | Ben Goldacre
Ben Goldacre: The same statistical errors – namely, ignoring the "difference in differences" – are appearing throughout the most prestigious journals in neuroscience
www.theguardian.com
March 14, 2025 at 11:33 AM
Anyone know if neuroscientists stopped doing this www.theguardian.com/commentisfre...
Reposted by Alfie Wearn
A new #Neurosalience episode is out! 🧠
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
Neurosalience #S5E10 with Simon Eickhoff - From Big Data to Biomarkers
YouTube video by Organization for Human Brain Mapping
youtu.be
March 6, 2025 at 11:50 AM
A new #Neurosalience episode is out! 🧠
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
From Big Data to Biomarkers
with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social
youtu.be/z91SiENsgF8
Reposted by Alfie Wearn
..and another one! 🤩 Join us for a great webinar in cooperation with the @istaart.bsky.social NSS PIA on studying neuromodulatory subcortical nuclei with multimodal MRI!
📅Date: April 9 - 10:00 am CT
💻Register here: alz-org.zoom.us/webinar/regi...
📅Date: April 9 - 10:00 am CT
💻Register here: alz-org.zoom.us/webinar/regi...
February 28, 2025 at 3:09 PM
..and another one! 🤩 Join us for a great webinar in cooperation with the @istaart.bsky.social NSS PIA on studying neuromodulatory subcortical nuclei with multimodal MRI!
📅Date: April 9 - 10:00 am CT
💻Register here: alz-org.zoom.us/webinar/regi...
📅Date: April 9 - 10:00 am CT
💻Register here: alz-org.zoom.us/webinar/regi...
Reposted by Alfie Wearn
The network of Alzheimer's Disease Research Centers is one of the most amazing NIH projects of all time: 33 sites collaborating to fight Alzheimer's in the lab and in the clinic at the same time. All of it in turmoil because the new funding is blocked.
Alzheimer’s disease will bankrupt the US healthcare system in 20 years if we don’t find better therapies now. The Trump administration is choking the largest national research collective on it.
If Alzheimer’s has touched your life, raise some hell.
www.baldwin.senate.gov/news/press-r...
If Alzheimer’s has touched your life, raise some hell.
www.baldwin.senate.gov/news/press-r...
Baldwin Blasts Trump Administration for Stopping $65 Million for Alzheimer’s Disease Research | U.S. Senator Tammy Baldwin of Wisconsin
WASHINGTON, D.C. – Today, U.S. Senator Tammy Baldwin (D-WI), Ranking Member of the Senate...
www.baldwin.senate.gov
March 3, 2025 at 11:36 PM
The network of Alzheimer's Disease Research Centers is one of the most amazing NIH projects of all time: 33 sites collaborating to fight Alzheimer's in the lab and in the clinic at the same time. All of it in turmoil because the new funding is blocked.
Reposted by Alfie Wearn
By @katherinejwu.com
"The NIH... supported 99 percent of the drugs approved in the U.S. from 2010 to 2019. The agency has had a hand in “nearly all of our major medical breakthroughs over the past several decades,”
The NIH is in a struggle for its (and our) lives. This is existential to America:
"The NIH... supported 99 percent of the drugs approved in the U.S. from 2010 to 2019. The agency has had a hand in “nearly all of our major medical breakthroughs over the past several decades,”
The NIH is in a struggle for its (and our) lives. This is existential to America:
Inside the Collapse at NIH
Administration officials pressured NIH to avoid clear advice from the agency’s own lawyers to restart grant funding now.
www.theatlantic.com
February 27, 2025 at 5:29 PM
By @katherinejwu.com
"The NIH... supported 99 percent of the drugs approved in the U.S. from 2010 to 2019. The agency has had a hand in “nearly all of our major medical breakthroughs over the past several decades,”
The NIH is in a struggle for its (and our) lives. This is existential to America:
"The NIH... supported 99 percent of the drugs approved in the U.S. from 2010 to 2019. The agency has had a hand in “nearly all of our major medical breakthroughs over the past several decades,”
The NIH is in a struggle for its (and our) lives. This is existential to America:
Reposted by Alfie Wearn
for pity’s sake, I am BEGGING university leaders to stop framing this issue in terms of what this will cost the university. people dont care!
EXPLAIN WHAT THIS WILL COST THE PUBLIC: closed hospitals and clinics, skipped treatments, loss of access to experimental drugs, unemployment, recession
EXPLAIN WHAT THIS WILL COST THE PUBLIC: closed hospitals and clinics, skipped treatments, loss of access to experimental drugs, unemployment, recession
February 9, 2025 at 10:00 PM
for pity’s sake, I am BEGGING university leaders to stop framing this issue in terms of what this will cost the university. people dont care!
EXPLAIN WHAT THIS WILL COST THE PUBLIC: closed hospitals and clinics, skipped treatments, loss of access to experimental drugs, unemployment, recession
EXPLAIN WHAT THIS WILL COST THE PUBLIC: closed hospitals and clinics, skipped treatments, loss of access to experimental drugs, unemployment, recession
Reposted by Alfie Wearn
New blogpost from our OHBM 2024 award winner series! 🧠
Dr. Rosanna Olsen @rosannaolsen.bsky.social, winner of the 2024 Diversity and Inclusivity Champion Award, reflects on her vision for a more inclusive scientific community.
Read here: www.ohbm-com.com/blog/55ubbep...
Dr. Rosanna Olsen @rosannaolsen.bsky.social, winner of the 2024 Diversity and Inclusivity Champion Award, reflects on her vision for a more inclusive scientific community.
Read here: www.ohbm-com.com/blog/55ubbep...
Interview with Dr. Rosanna Olsen, 2024 Winner of the Diversity & Inclusivity Champion Award — OHBM Communications
Author: Ashley Tyrer Editor: Simon R. Steinkamp
www.ohbm-com.com
February 17, 2025 at 2:31 PM
New blogpost from our OHBM 2024 award winner series! 🧠
Dr. Rosanna Olsen @rosannaolsen.bsky.social, winner of the 2024 Diversity and Inclusivity Champion Award, reflects on her vision for a more inclusive scientific community.
Read here: www.ohbm-com.com/blog/55ubbep...
Dr. Rosanna Olsen @rosannaolsen.bsky.social, winner of the 2024 Diversity and Inclusivity Champion Award, reflects on her vision for a more inclusive scientific community.
Read here: www.ohbm-com.com/blog/55ubbep...
Reposted by Alfie Wearn
NIH and Its Agencies Are Being Smothered talkingpointsmemo.com/edblog/nih-a...
NIH and Its Agencies Are Being Smothered
In recent days I have been inundated by reports out of HHS...
talkingpointsmemo.com
February 14, 2025 at 4:40 PM
NIH and Its Agencies Are Being Smothered talkingpointsmemo.com/edblog/nih-a...
Reposted by Alfie Wearn
Now over 900 signatures. Please keep signing and sharing to send a clear message to the Royal Society that we want them to stand up for values that we all hold dear: docs.google.com/forms/d/e/1F...
February 12, 2025 at 8:30 PM
Now over 900 signatures. Please keep signing and sharing to send a clear message to the Royal Society that we want them to stand up for values that we all hold dear: docs.google.com/forms/d/e/1F...