Alexa Sadier
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aigverte.bsky.social
Alexa Sadier
@aigverte.bsky.social
1.4K followers 910 following 220 posts
CNRS PI at Institut des Sciences de l'Evolution de Montpellier | Evo-devo - Bats - Teeth - Dev Constraints - Adaptation | Evolution on Earth and beyond | ERC NOVELTEETH |
Co-host @podcastscience | Cham steepskier
website: alexasadier.com
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aigverte.bsky.social
Alexa Sadier @aigverte.bsky.social · Sep 24
Comme il y a beaucoup de nouveaux arrivants, c'est le moment d'une nouvelle présentation ! Je suis chercheuse en biologie évolutive du développement et dans mon équipe, nous essayons de comprendre comment et par quels mécanismes les espèces (et surtout les chiroptères !! 🦇) se diversifient 👇🧵
Artibeus jamaicensis, credit Alexa Sadier
Reposted by Alexa Sadier
gregpriest.bsky.social
Conrad Hal Waddington was born OTD in 1905.

His “epigenetic landscape” is a diagrammatic representation of the constraints influencing embryonic development.

On his 50th birthday, his colleagues gave him a pinball machine on the model of the epigenetic landscape.

🧪 🦫🦋 🌱🐋 #HistSTM #philsci #evobio
November 8, 2025 at 4:03 PM
Reposted by Alexa Sadier
batconservation.bsky.social
🦇 #NameThatBat ! Help us choose collective nouns for bats this autumn: www.bats.org.uk/news/2025/11... .

Halloween may be over — but we still need your help to #NameThatBat! Join in and vote in Bat Conservation Trust's first bat naming competition.
November 6, 2025 at 9:26 AM
Reposted by Alexa Sadier
juliengossa.cpesr.fr
[ #VeilleESR #PLF2026 ] Audition du ministre de l'enseignement supérieur

Retranscription : seafile.unistra.fr/f/be9b46d765...

Je viens de faire un thread de ouatemille posts, qui a foiré et j'ai tour perdu. J'y bosse depuis 4 heures, donc je vais pas refaire. Les principaux trucs.
Audition de M. Philippe Baptiste, ministre de l’enseignement supérieur, de la recherche et de l’espace, sur le projet de loi de finances pour 2026 - Pierre OUZOULIAS
29 octobre 2025
videos.senat.fr
November 5, 2025 at 11:59 AM
Reposted by Alexa Sadier
vincentdebat.bsky.social
Finally out in Elife @elife.bsky.social : well done @joledamoisel.bsky.social ! Convergent iridescence and divergent chemical signals in sympatric sister-species of Amazonian butterflies doi.org/10.7554/eLif...
November 6, 2025 at 9:47 AM
Reposted by Alexa Sadier
dduneau.bsky.social
Very excited to share this collaboration with @pbeldade.bsky.social! We explore how the interaction between immune function and developmental processes shapes morphological plasticity in response to temperature.
bmcbiol.biomedcentral.com/articles/10....
November 4, 2025 at 4:39 PM
Reposted by Alexa Sadier
plosbiology.org
#Evolution of complex adaptations can involve changes in multiple traits that lack standalone function. @benitoexplains.bsky.social &co show that leaf masquerade in #katydids evolved via concurrent modification in wing colour & shape, driven by evolutionary synergy @plosbiology.org 🧪 plos.io/4oUE741
Functional synergy underlies effective leaf masquerade in the wild. Top: Photographs of Itarissa costaricensis (left) and Aegmia maculofolia (right), leaf-masquerading katydid species (Orthoptera: Tettigoniidae) found at the field site in Panama. Photos courtesy of Dr Hannah ter Hofstede and Dr Laurel Symes. Bottom: All experimental color × shape treatment combinations in situ, pinned to tree bark with a mealworm (Tenebrio molitor larvae) as bait. From left to right: “green oval,” “green elongated oval,” “green rectangle,” “brown oval,” “brown elongated oval,” “brown rectangle,” “blue oval,” “blue elongated rectangle,” “blue rectangle.”
November 4, 2025 at 1:55 PM
aigverte.bsky.social
Hallucinant. C'est inacceptable. J'ai une ERC, que rétrospectivement j'ai eu la chance de rédiger à l'étranger avec un dispositif bien meilleur que ceux qui sont proposés en France et SURTOUT avec de quoi produire des résultats préliminaires que ce soit en terme de mentiring ou de moyens #esr
cedricbrun.bsky.social Cédric Brun @cedricbrun.bsky.social · 11d
Quand notre ministre de tutelle nous insulte devant la représentation nationale. "Bande de nuls" "complètement à la ramasse".
Nous reprocher des taux de réussite faible à Horizon Europe et ERC, quand manquent les moyens pour assurer nos missions de service public. Surtout changez rien!👌
October 31, 2025 at 10:29 AM
Reposted by Alexa Sadier
jpascualanaya.bsky.social
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
October 30, 2025 at 5:50 PM
Reposted by Alexa Sadier
sicbjournals.bsky.social
ICB's spotlight on
@aigverte.bsky.social co author on
doi.org/10.1093/icb/...
for #BatWeek
connect (@)explorabats Insta
alexasadier.com/index.php/fi...
& check out the trailer for the doc Sadier is part of
with the people of Trinidad (and our research of course)
alexasadier.com/index.php/sc...
October 29, 2025 at 11:54 AM
Reposted by Alexa Sadier
sebastienbouret.bsky.social
Les extrêmes mettent en danger notre démocratie mais aussi la science et la santé. J’ai cosigné une tribune publiée dans Le Monde aujourd’hui pour dénoncer les amendements LFI/RN visant à taxer l’expérimentation animale car ils constituent une menace pour la recherche et les découvertes médicales 🔬
Budget 2026 : « La taxation des expérimentations animales mettrait en péril la recherche en France »
TRIBUNE. Dans une tribune au « Monde », des représentants de sociétés savantes, de fondations, d’associations et de réseaux scientifiques mettent en garde contre le dépôt d’amendements au projet de lo...
www.lemonde.fr
October 28, 2025 at 5:55 PM
Reposted by Alexa Sadier
pawelburkhardt.bsky.social
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience

Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E

@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
Reposted by Alexa Sadier
nhm-london.bsky.social
If you’re looking for something a little less scary, keep an eye out for the bat adorning our building! 🦇
A sculpture of a bat with its wings wide open with vegetation beneath it. The sculpture is attached to the top of a column.
October 28, 2025 at 3:45 PM
Reposted by Alexa Sadier
sicbjournals.bsky.social
ICB celebrates #BatWeek
#Bat #Dentitions: A Model System for Studies at the Interface of Development, #Biomechanics, and #Evolution

Sharlene E Santana, David M Grossnickle, Alexa Sadier, Edward Patterson, Karen E Sears

doi.org/10.1093/icb/...

#science #biology #teeth #mammals
Fig. 1Two models of bite force variation along the tooth row. A) in an unconstrained model, bite force is proportional to the moment (Mj) about the jaw joint (temporomandibular joint, TMJ), which can be calculated as the sum of the moments about the TMJ produced by the jaw adductor muscles (temporalis and masseter) divided by the outlever (distance between the bite point and the TMJ). Bite force is predicted to increase at more posterior bite points along the tooth row. B) in a constrained model proposed by Greaves (1978, 2002) and Spencer (1995, 1999), a triangle of support (shaded area) is defined by the bite point and the working and balancing jaw joint reaction forces; a midline mandible muscle resultant force passes through this triangle during more anterior biting, and has to be repositioned toward the working side of the mandible to avoid tension in the jaw joint during more posterior biting. C) based on perpendicular and oblique planes drawn based on the position of the mandible muscle resultant force, Greaves (1978, 2002) proposed three bite force regions: Region I, in which bite force increases posteriorly as in the unconstrained model; Region II, the region of maximum bite force; and Region III, with the lowest bite force because biting would be associated with dislocation of the balancing side jaw joint. Bite force is predicted to increase, reach a maximum, and then decrease posteriorly along the mandible.
October 27, 2025 at 11:23 AM
Reposted by Alexa Sadier
fishfetisher.bsky.social
Why are some species smaller than a paperclip while others grow longer than a school bus? How is body size evolution governed in animals? Out now in @pnas.org we tackle these longstanding questions through a genetic lens using my favorite group of fishes as our model!! www.pnas.org/doi/10.1073/...
Parallel shifts in differential gene expression reveal convergent miniaturization in fishes | PNAS
Body size variation in vertebrates is a complex polygenic trait, tightly correlated with numerous aspects of a species’ biology, ecology, and physi...
www.pnas.org
October 22, 2025 at 9:33 PM
Reposted by Alexa Sadier
plantevodevo-ab.bsky.social
🌱 Open PhD Position in Plant EvoDevo 🌱 Thinking about a PhD in plant evodevo? The Becker Research Group (JLU Giessen, Germany) has a fully funded 4-year PhD position in the ICIPS II research unit! 🎓 📍 Where? Gießen, Germany – great research environment & vibrant plant science network.
tinyurl.com
October 23, 2025 at 11:52 AM
Reposted by Alexa Sadier
batconservation.bsky.social
What is a roost? Here are some bat roost facts:

🪹 Bats do not make nests, but choose various places throughout the year to shelter, live and sleep in.
🦇 Where bats choose to roost varies between species and the time of the year.
📍 They don't stay in the same roost the whole year.
October 19, 2025 at 9:36 AM
Reposted by Alexa Sadier
biologists.bsky.social
“Developmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”

Read this insightful post by Bethan on the Node.

thenode.biologists.com/developmenta...

#Disability
Developmental Biology and Disability - the Node
Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.
thenode.biologists.com
October 22, 2025 at 1:15 PM
Reposted by Alexa Sadier
coastalpaleo.bsky.social
#toothtuesday Fur seals and sea lions evolved from ancestors with double-rooted teeth - but evolved single rooted teeth over the past five million years. Shown here is the 'anagenetic' evolution of the northern fur seal, Callorhinus ursinus. Read more here: coastalpaleo.blogspot.com/2025/10/the-...
Evolution of the northern fur seal (Callorhinus) lineage over the last five million years. On the left is a series of diagrams showing the gradual fusion of the postcanine tooth roots, and on the right are photos of the actual fossils - the possibly ancestral Thalassoleon mexicanus through Callorhinus gilmorei, the early Pleistocene unnamed Callorhinus sp., and the modern Callorhinus ursinus.
October 21, 2025 at 5:17 PM
Reposted by Alexa Sadier
elisecutts.bsky.social
If you're a science journalist (or aspiring science journalist) who's been writing regularly in English for less than 3 years (not counting student work/internships), check out the @theopennotebook.bsky.social Early-Career Fellowship.

The deadline is October 31, so there's still time to apply.
Early-Career Fellowship Program - The Open Notebook
Every year, The Open Notebook offers a paid, part-time fellowship program for early-career science journalists. This ten-month program offers fellows the opportunity to explore their career interests ...
www.theopennotebook.com
October 21, 2025 at 11:43 AM
Reposted by Alexa Sadier
reto-burri.bsky.social
1/9 New in @science.org www.science.org/doi/10.1126/science.ado8005
How does genetic architecture constrain evolutionary trajectories? To address this question, we inferred the genetic architecture of convergent plumage coloration and its evolutionary history in wheatears.
A mosaic of modular variation at a single gene underpins convergent plumage coloration
The reshuffling of genomic variation from multiple origins is an important contributor to phenotypic diversification, yet insights into the evolutionary trajectories of this combinatorial process and ...
www.science.org
October 17, 2025 at 5:50 AM
Reposted by Alexa Sadier
mixlamalice.bsky.social
Je suis peut-être dans le déni mais en même temps ça fait deux fois en 10 ans que j'entends exactement les mêmes prophéties: "tout est gratuit et en ligne, les profs ne servent à rien et vont disparaître". La première fois c'était avec les MOOC. Vu ce que ça a donné, je reste assez zen.
porcupunk.bsky.social Vlad K. @porcupunk.bsky.social · 26d
Wow. Just wow.

"Students pay premium prices for information that AI now delivers instantly and for free. A business student can ask ChatGPT to explain supply chain optimization or generate market analysis in seconds. The traditional lecture-and-test model faces its Blockbuster moment."
When Knowledge is Free, What are Professors For?
Higher Education Must Stop Competing with AI on Information and Start Teaching What Machines Can’t Do
www.forbes.com
October 17, 2025 at 8:03 AM
Reposted by Alexa Sadier
danielibrahim.bsky.social
What is a promoter? And how does it work?

We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters

www.biorxiv.org/content/10.1...
Enhancer-promoter compatibility is mediated by the promoter-proximal region
Gene promoters induce transcription in response to distal enhancers. How enhancers specifically activate their target promoter while bypassing other promoters remains unclear. Here, we find that the p...
www.biorxiv.org
October 16, 2025 at 3:06 PM
Reposted by Alexa Sadier
gcbias.bsky.social
Congratulations to @jeffgroh.bsky.social on the publication of his paper on an ancient balanced polymorphisms controlling heterodichogamy in two genera of wingnuts. The paper shows the putative turnover & reversal of dominance of a mating type polymorphism
www.sciencedirect.com/science/arti...
Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts
In the angiosperm mating system of heterodichogamy, two hermaphroditic morphs temporally alternate between male and female flowering phases, promoting…
www.sciencedirect.com
October 16, 2025 at 3:42 PM
Reposted by Alexa Sadier
ebardot.bsky.social
Lots of great discussion about developmental variability here at #GastrulationReloaded! Super important to consider, and current tools have the power for this.

Related to this recent paper showing that mild phenotypes are more variable than severe ones. www.nature.com/articles/s41...
A quadratic paradigm describes the relationship between phenotype severity and variation - Nature Communications
Phenotype variation is higher in mutants than wild types. Examining a range of mutant severities, this study unexpectedly found that variation decreases in severe conditions. A quadratic trend best fi...
www.nature.com
October 15, 2025 at 9:24 AM