🪼 How did the animal body plan evolve?

This ‘fundamental’ study in Clytia sheds light on how Wnt3 coordinates both gene expression and planar cell polarity during axis formation, offering key insights into the origins of morphogenesis.
buff.ly/lLJ33VF
#DevBio

Meet Camila Sánchez!

A postbac in Riccardo Papa’s lab studying wing development in 𝑯𝒆𝒍𝒊𝒄𝒐𝒏𝒊𝒖𝒔 butterflies. Using FISH technique, she tracks where and when genes like Wnt3 are expressed—mapping the pathways that shape wing color patterns.

🪼 How did the animal body plan evolve?

This ‘fundamental’ study in Clytia sheds light on how Wnt3 coordinates both gene expression and planar cell polarity during axis formation, offering key insights into the origins of morphogenesis.
elifesciences.org/articles/104...
#DevBio

Tsuyo's cool paper on Wnt3 being both a canonical and a PCP Wnt in Clytia is out doi.org/10.7554/eLif... Congratulations to everyone involved! @biodev-vlfr.bsky.social

🪼 How did the animal body plan evolve?

This ‘fundamental’ study in Clytia sheds light on how Wnt3 coordinates both gene expression and planar cell polarity during axis formation, offering key insights into the origins of morphogenesis.
buff.ly/e1Un958
#DevBio

Secretion and signaling properties of Wnt11 and Wnt3 are determined by their N-terminus https://www.biorxiv.org/content/10.1101/2025.07.02.662750v1

Secretion and signaling properties of Wnt11 and Wnt3 are determined by their N-terminus https://www.biorxiv.org/content/10.1101/2025.07.02.662750v1

Over the next few days at #biologists100, try to catch @joyceyu.bsky.social with the Node's polaroid frame 📸

We'd love to promote you and your research: write your name and key words of things you're passionate about, and smile! 😃

Here's an example from our reporter @jens-cells.bsky.social #Wnt3

Homo Sapiens

WNT1, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10A, WNT10B, WNT11, WNT16

Chromosome 19

This is cool, Andy. But it might even be a bit older. Here is an image from Muller et al. (2007), showing Wnt3 expression at the tip of the #Hydractinia male sporosac. this is the point from which they spawn. Would be interesting to look at some other genes.

Have a look at our last review on Organizer formation, organizer maintenance and epithelial cell plasticity in Hydra: Role of the Wnt3/β-catenin/TCF/Sp5/Zic4 gene network, just published in Cells & Development
doi.org/10.1016/j.cd...

I literally just found out about @sticknation.bsky.social last night. Are you in the club?
www.youtube.com/watch?v=WNt3...

#バーチャル音楽ライブtopia で配信中
live.topia.tv/wnt3?x=99ebe...

New preprint! We have shown that WNT2B is critical for resistance to inflammation in the colon, so we wondered whether it was important in the immature small intestine, before Wnt3 expression from Paneth cells goes up...
#NEC #intestine #SciSky #epithelium
www.biorxiv.org/content/10.1...

How much of the variability in Parkinson's genetics is actually epistasis which is the statistical interaction between two or more genetic variants? Hint: Something interesting is present in SNCA, MAPT and WNT3. Cisterna-Garcia and colleagues tackled this in the latest article in the journal Brain.

"vodu é pra jacu", aprendi com o Pica-Pau
www.youtube.com/watch?v=Wnt3...

HyWnt3-ΔRep-D4:Luc
Depositor: Brigitte Galliot
Purpose: Plasmid to test the Hydra Wnt3 promoter activity (partial deletion of the repressor element-D4)

www.addgene.org/192991/