December 17, 2025 at 8:04 AM
@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
November 6, 2025 at 6:40 AM
@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
Hablando con @adrian_science sobre ‘el dia 14. Como las células diseñan la vida’ y sus cuitas con los #genes
shorturl.at/oZcyf
en castellano.
Mas en @EdicionesPaidos “Las arquitectas de la vida’
#NotInTheGenes #CellsRUs
shorturl.at/oZcyf
en castellano.
Mas en @EdicionesPaidos “Las arquitectas de la vida’
#NotInTheGenes #CellsRUs
August 6, 2025 at 11:13 AM
Hablando con @adrian_science sobre ‘el dia 14. Como las células diseñan la vida’ y sus cuitas con los #genes
shorturl.at/oZcyf
en castellano.
Mas en @EdicionesPaidos “Las arquitectas de la vida’
#NotInTheGenes #CellsRUs
shorturl.at/oZcyf
en castellano.
Mas en @EdicionesPaidos “Las arquitectas de la vida’
#NotInTheGenes #CellsRUs
Today is a special day, some would call it the first of the rest of my life.
I look forward to doing the same as before, from a different vantage point, trying to use what I have learnt to keep on learning. Thank you to all who have taught me.
#NotInTheGenes #CellsRUs
I look forward to doing the same as before, from a different vantage point, trying to use what I have learnt to keep on learning. Thank you to all who have taught me.
#NotInTheGenes #CellsRUs
October 1, 2025 at 4:56 PM
Today is a special day, some would call it the first of the rest of my life.
I look forward to doing the same as before, from a different vantage point, trying to use what I have learnt to keep on learning. Thank you to all who have taught me.
#NotInTheGenes #CellsRUs
I look forward to doing the same as before, from a different vantage point, trying to use what I have learnt to keep on learning. Thank you to all who have taught me.
#NotInTheGenes #CellsRUs
The passing of A. Garcia Bellido
es.wikipedia.org/wiki/Antonio...
means another pioneer of #DevBiol leaving the room. An impactful personality who could create an intellectual storm w/ a sentence.
Here from a discussion with L Wolpert pubmed.ncbi.nlm.nih.gov/9654040/
#Drosophila #CellsRUs #Genes
es.wikipedia.org/wiki/Antonio...
means another pioneer of #DevBiol leaving the room. An impactful personality who could create an intellectual storm w/ a sentence.
Here from a discussion with L Wolpert pubmed.ncbi.nlm.nih.gov/9654040/
#Drosophila #CellsRUs #Genes
November 14, 2025 at 11:44 AM
The passing of A. Garcia Bellido
es.wikipedia.org/wiki/Antonio...
means another pioneer of #DevBiol leaving the room. An impactful personality who could create an intellectual storm w/ a sentence.
Here from a discussion with L Wolpert pubmed.ncbi.nlm.nih.gov/9654040/
#Drosophila #CellsRUs #Genes
es.wikipedia.org/wiki/Antonio...
means another pioneer of #DevBiol leaving the room. An impactful personality who could create an intellectual storm w/ a sentence.
Here from a discussion with L Wolpert pubmed.ncbi.nlm.nih.gov/9654040/
#Drosophila #CellsRUs #Genes
The variability of early mammalian embryos never ceases to amaze me. Beautiful work on the emergence of PGCs in the cow from @carlyguiltinan www.biorxiv.org/content/10.1...
But look at the embryo amidst the enormous trophectoderm! Could you find it w/o epiblast markers?
#Amazing #Stunning #CellsRUs
But look at the embryo amidst the enormous trophectoderm! Could you find it w/o epiblast markers?
#Amazing #Stunning #CellsRUs
August 27, 2025 at 8:34 AM
The variability of early mammalian embryos never ceases to amaze me. Beautiful work on the emergence of PGCs in the cow from @carlyguiltinan www.biorxiv.org/content/10.1...
But look at the embryo amidst the enormous trophectoderm! Could you find it w/o epiblast markers?
#Amazing #Stunning #CellsRUs
But look at the embryo amidst the enormous trophectoderm! Could you find it w/o epiblast markers?
#Amazing #Stunning #CellsRUs
Looking forward to discussing why “genetics is not that simple” tomorrow in Lisboa. Thank you Fundacao Francisco Manues do Santos and GIMM for the opportunity
ffms.pt/en/agenda/al...
#NotInTheGenes #CellsRUs #Gastrulation
ffms.pt/en/agenda/al...
#NotInTheGenes #CellsRUs #Gastrulation
November 3, 2025 at 5:37 AM
Looking forward to discussing why “genetics is not that simple” tomorrow in Lisboa. Thank you Fundacao Francisco Manues do Santos and GIMM for the opportunity
ffms.pt/en/agenda/al...
#NotInTheGenes #CellsRUs #Gastrulation
ffms.pt/en/agenda/al...
#NotInTheGenes #CellsRUs #Gastrulation
Need to put an effort to understand cells, the interpreters and users of the genes
#CellsRUs #NotInTheGenes
#CellsRUs #NotInTheGenes
September 4, 2025 at 8:45 AM
Need to put an effort to understand cells, the interpreters and users of the genes
#CellsRUs #NotInTheGenes
#CellsRUs #NotInTheGenes
There is an echo here of the situation in #gastruloids where it is possible to see un uncoupling between #GRNs and #CRNs (cell regulatory networks) www.sciencedirect.com/science/arti...
#CellsRUs
#CellsRUs
July 28, 2025 at 8:48 AM
There is an echo here of the situation in #gastruloids where it is possible to see un uncoupling between #GRNs and #CRNs (cell regulatory networks) www.sciencedirect.com/science/arti...
#CellsRUs
#CellsRUs
Thank you. Glad to read this. In order to solve problems, to have answers, we need questions and to raise them was, is, one of the aims of the argument here. #NotInTheGenes #CellsRUs
There is no better way to end the book year than this! I have never read a book that has raised so many questions & left me speechless at the same time! „The Master Builder“ by @amartinezarias.bsky.social is truly a masterpiece!👏🧠🔬
„..it is cells, not genes, that make you and me what we are.“
„..it is cells, not genes, that make you and me what we are.“
December 31, 2024 at 5:26 PM
Thank you. Glad to read this. In order to solve problems, to have answers, we need questions and to raise them was, is, one of the aims of the argument here. #NotInTheGenes #CellsRUs
Nice account of a scientific journey and, a tale of #gastruloids. It is good to see that, in addition to telling us about the component elements of embryos they allow to explore physical principles of #SelfOrganization in context of embryo building #CellsRUs #MasterBuilder
P.S. for some scientific content, check out this 'behind the paper' post I wrote for @the-node.bsky.social describing the background and origin story of our recent study using signal-recording genetic circuits to decode gastruloid symmetry breaking!
thenode.biologists.com/behind-the-p...
thenode.biologists.com/behind-the-p...
Behind the paper stories - the Node
Behind the paper stories Every paper has a story behind it, and we regularly commission scientists to tell theirs. In this collection you'll discover the
thenode.biologists.com
January 18, 2025 at 7:16 AM
Nice account of a scientific journey and, a tale of #gastruloids. It is good to see that, in addition to telling us about the component elements of embryos they allow to explore physical principles of #SelfOrganization in context of embryo building #CellsRUs #MasterBuilder
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
September 22, 2025 at 9:01 PM
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
Just heard @wcratcliff.bsky.social on the origin of #multicellularity www.youtube.com/watch?v=MsvD...
Great to hear that cells harnessing physics was a significant step & to have a proper discussion of the question not led by the ‘power’ of genes. Well worth a listen.
#NotInTheGenes #CellsRus
Great to hear that cells harnessing physics was a significant step & to have a proper discussion of the question not led by the ‘power’ of genes. Well worth a listen.
#NotInTheGenes #CellsRus
How Did Multicellular Life Evolve? | Podcast: The Joy of Why
YouTube video by Quanta Magazine
www.youtube.com
August 1, 2025 at 8:11 AM
Just heard @wcratcliff.bsky.social on the origin of #multicellularity www.youtube.com/watch?v=MsvD...
Great to hear that cells harnessing physics was a significant step & to have a proper discussion of the question not led by the ‘power’ of genes. Well worth a listen.
#NotInTheGenes #CellsRus
Great to hear that cells harnessing physics was a significant step & to have a proper discussion of the question not led by the ‘power’ of genes. Well worth a listen.
#NotInTheGenes #CellsRus
“A goal for the future would be to determine the extent of knowledge the cell has of itself and how it utilizes this knowledge in a ‘thoughtful’ manner when challenged”
Barbara McClintock Nobel lecture 1983
#CellsRUs #NotInTheGenes #MasterBuilder
Barbara McClintock Nobel lecture 1983
#CellsRUs #NotInTheGenes #MasterBuilder
December 8, 2024 at 12:35 PM
“A goal for the future would be to determine the extent of knowledge the cell has of itself and how it utilizes this knowledge in a ‘thoughtful’ manner when challenged”
Barbara McClintock Nobel lecture 1983
#CellsRUs #NotInTheGenes #MasterBuilder
Barbara McClintock Nobel lecture 1983
#CellsRUs #NotInTheGenes #MasterBuilder
Right after the spanish edition of #TheMasterBuilder comes the Portuguese one, thanks to www.temasedebates.pt
Have a look for a cell’s eye view of Biology in contrast with the widespread gene’s eye.
#CellsRUs #NotInTheGenes
Have a look for a cell’s eye view of Biology in contrast with the widespread gene’s eye.
#CellsRUs #NotInTheGenes
March 28, 2025 at 8:18 AM
Right after the spanish edition of #TheMasterBuilder comes the Portuguese one, thanks to www.temasedebates.pt
Have a look for a cell’s eye view of Biology in contrast with the widespread gene’s eye.
#CellsRUs #NotInTheGenes
Have a look for a cell’s eye view of Biology in contrast with the widespread gene’s eye.
#CellsRUs #NotInTheGenes
With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs
September 22, 2025 at 2:40 PM
With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs
3D human #amnion model. We are a veritable cellular lego cell.com/cell/fulltex... Very good piece of work, with a focus on the important aspect of this organ #physiology.
@SantosLaB8
#CellsRUS #SCBM #EmbryoModels
@SantosLaB8
#CellsRUS #SCBM #EmbryoModels
Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development
An embryonic stem cell-based 3D model that accurately recapitulates the size, morphology,
and functional features of the human amnion at 4 weeks, termed the post-gastrulation
amnioid (PGA), is develop...
cell.com
May 19, 2025 at 5:26 PM
3D human #amnion model. We are a veritable cellular lego cell.com/cell/fulltex... Very good piece of work, with a focus on the important aspect of this organ #physiology.
@SantosLaB8
#CellsRUS #SCBM #EmbryoModels
@SantosLaB8
#CellsRUS #SCBM #EmbryoModels
What happens when you plate #gastruloids at different times on different subtstrates is that we learn about cells, pattern formation and gastrulation. Excellent experiments from G. Serrano and @bensteventon.bsky.social raising interesting questions www.biorxiv.org/content/10.1...
#CellsRUs
#CellsRUs
August 6, 2025 at 3:49 PM
What happens when you plate #gastruloids at different times on different subtstrates is that we learn about cells, pattern formation and gastrulation. Excellent experiments from G. Serrano and @bensteventon.bsky.social raising interesting questions www.biorxiv.org/content/10.1...
#CellsRUs
#CellsRUs
Yamini @yamini-ravichan.bsky.social changed the topology of Hydra to show that actin orientational defects of Hydra induce the full program of head regeneration: www.science.org/doi/10.1126/...
Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.
Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.
January 20, 2025 at 9:12 AM
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:52 AM
Organizing time past, remembered this summary of many thoughts that I continue to pursue
And nowhere rings more true that ‘the detail of pattern is the movement’ than in the actions of cells as they build #embryos
www.youtube.com/watch?v=bbQV...
#CellsRUs #MasterBuilder
And nowhere rings more true that ‘the detail of pattern is the movement’ than in the actions of cells as they build #embryos
www.youtube.com/watch?v=bbQV...
#CellsRUs #MasterBuilder
Landscapes and embryos : A film from A. Martinez Arias
YouTube video by Cambridge University
www.youtube.com
October 3, 2025 at 7:40 AM
Organizing time past, remembered this summary of many thoughts that I continue to pursue
And nowhere rings more true that ‘the detail of pattern is the movement’ than in the actions of cells as they build #embryos
www.youtube.com/watch?v=bbQV...
#CellsRUs #MasterBuilder
And nowhere rings more true that ‘the detail of pattern is the movement’ than in the actions of cells as they build #embryos
www.youtube.com/watch?v=bbQV...
#CellsRUs #MasterBuilder