#MatrixStiffness controls hypertrophic responses of #SmoothMuscleCell to ANGII/Carbachol

12 kPa
ANGII⏬cell area, not cell volume/height (How🤔)
72 kPa
ANGII⏫cell area/volume, not height

#Piezo1-PKC-#Aquaporin1 cascade

#BrJPharmacol 2023
bpspubs.onlinelibrary.wiley.com/doi/10.1111/...

MedSky🧪#IDSky #EpiSky #Neurobiology #Immunology @BrJPharmacol Understanding Autocrine positive feedback of tumor necrosis factor (TNF) from activated #microglia proposed to be of widespread relevance in chronic neurological disease