@zfreyberg.bsky.social
Reposted
We are pleased to announce Doppio version 1.4! Available here www.ccpem.ac.uk/software/dow...
Downloads – CCP-EM
www.ccpem.ac.uk
November 4, 2025 at 5:38 PM
We are pleased to announce Doppio version 1.4! Available here www.ccpem.ac.uk/software/dow...
Excited about a new paper by the amazing #EvaMartinSolana #SoniaFrendi #JiyingNing #TabithaBanksTibbs and #JerryVockley where we offer a step-by-step protocol for preparing cells for #cryo-electron tomography!
#TeamTomo
onlinelibrary.wiley.com/share/author...
#TeamTomo
onlinelibrary.wiley.com/share/author...
currentprotocols.onlinelibrary.wiley.com
October 28, 2025 at 8:10 PM
Excited about a new paper by the amazing #EvaMartinSolana #SoniaFrendi #JiyingNing #TabithaBanksTibbs and #JerryVockley where we offer a step-by-step protocol for preparing cells for #cryo-electron tomography!
#TeamTomo
onlinelibrary.wiley.com/share/author...
#TeamTomo
onlinelibrary.wiley.com/share/author...
Reposted
The Giant Synapse Symposium - a free, one-day event focused on synaptic function - will place on Nov. 14th, the day before the start of SFN: shorturl.at/AwLqE. Please consider attending or spreading the word.
General Info - Giant Synapse Symposium 2025. Online registration by Cvent
shorturl.at
October 22, 2025 at 10:13 PM
The Giant Synapse Symposium - a free, one-day event focused on synaptic function - will place on Nov. 14th, the day before the start of SFN: shorturl.at/AwLqE. Please consider attending or spreading the word.
Reposted
⏰The clock is ticking to get your LOI submitted for the
2026 Parkinson's Foundation Postdoctoral Fellowship! Applications close Wednesday, 10/22 at 3:00pm 😱
For more information and to apply, please visit: www.parkinson.org/advancing-re...
2026 Parkinson's Foundation Postdoctoral Fellowship! Applications close Wednesday, 10/22 at 3:00pm 😱
For more information and to apply, please visit: www.parkinson.org/advancing-re...
Fellowships & Early Career Awards
Awarded to encourage young scientists, clinicians and students to devote their talents to the study of PD.
www.parkinson.org
October 14, 2025 at 3:36 PM
⏰The clock is ticking to get your LOI submitted for the
2026 Parkinson's Foundation Postdoctoral Fellowship! Applications close Wednesday, 10/22 at 3:00pm 😱
For more information and to apply, please visit: www.parkinson.org/advancing-re...
2026 Parkinson's Foundation Postdoctoral Fellowship! Applications close Wednesday, 10/22 at 3:00pm 😱
For more information and to apply, please visit: www.parkinson.org/advancing-re...
Reposted
Great Job - Great Colleagues - Great Science👍
Help us pick the next generation of @hhmi.org Investigators, Freeman Hrabowski Scholars, Hanna Gray Fellows, Gilliam Fellows
Relocation to DC is required, perfect for academic PIs looking for their next chapter
hhmi.wd1.myworkdayjobs.com/External/job...
Help us pick the next generation of @hhmi.org Investigators, Freeman Hrabowski Scholars, Hanna Gray Fellows, Gilliam Fellows
Relocation to DC is required, perfect for academic PIs looking for their next chapter
hhmi.wd1.myworkdayjobs.com/External/job...
Senior Director - Scientific Officer
Primary Work Address: 4000 Jones Bridge Road, Chevy Chase, MD, 20815 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the disco...
hhmi.wd1.myworkdayjobs.com
October 9, 2025 at 9:48 PM
Great Job - Great Colleagues - Great Science👍
Help us pick the next generation of @hhmi.org Investigators, Freeman Hrabowski Scholars, Hanna Gray Fellows, Gilliam Fellows
Relocation to DC is required, perfect for academic PIs looking for their next chapter
hhmi.wd1.myworkdayjobs.com/External/job...
Help us pick the next generation of @hhmi.org Investigators, Freeman Hrabowski Scholars, Hanna Gray Fellows, Gilliam Fellows
Relocation to DC is required, perfect for academic PIs looking for their next chapter
hhmi.wd1.myworkdayjobs.com/External/job...
Reposted
Our Impact Award LOI applications close THIS FRIDAY at 3:00pm Eastern! 😮 For more information and to apply, please visit: www.parkinson.org/advancing-re...
@parkinsondotorg.bsky.social
@parkinsondotorg.bsky.social
Awards for Independent Investigators
Awards for independent investigators that we offer to advance Parkinson's research.
www.parkinson.org
October 7, 2025 at 4:47 PM
Our Impact Award LOI applications close THIS FRIDAY at 3:00pm Eastern! 😮 For more information and to apply, please visit: www.parkinson.org/advancing-re...
@parkinsondotorg.bsky.social
@parkinsondotorg.bsky.social
Reposted
Antipsychotic Drugs and Dysregulated Glucose Homeostasis
#psychiatry #metabolism #drug-response #antipsychotics 🧪
jamanetwork.com/journals/jam...
#psychiatry #metabolism #drug-response #antipsychotics 🧪
jamanetwork.com/journals/jam...
Antipsychotic Drugs and Dysregulated Glucose Homeostasis
This systematic review and meta-analysis examines the association between antipsychotic drug use and glucose homeostasis while considering weight gain propensity, medication type, and treatment durati...
jamanetwork.com
October 3, 2025 at 2:59 PM
Antipsychotic Drugs and Dysregulated Glucose Homeostasis
#psychiatry #metabolism #drug-response #antipsychotics 🧪
jamanetwork.com/journals/jam...
#psychiatry #metabolism #drug-response #antipsychotics 🧪
jamanetwork.com/journals/jam...
Reposted
Applications are now open for our UMMC Graduate Program in Neuroscience! Join a dynamic and collaborative environment where students work at the forefront of neuroscience—from molecules to behavior. 🧬🧠✨Application deadline: December 15. Apply here! lnkd.in/eSe2rwG
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
October 4, 2025 at 8:10 PM
Applications are now open for our UMMC Graduate Program in Neuroscience! Join a dynamic and collaborative environment where students work at the forefront of neuroscience—from molecules to behavior. 🧬🧠✨Application deadline: December 15. Apply here! lnkd.in/eSe2rwG
Reposted
The new issue of #ScienceSignaling is out!
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
September 9, 2025 at 9:00 PM
The new issue of #ScienceSignaling is out!
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
Reposted
⚠️ART. "Fármacos antipsicóticos y homeostasis de glucosa desregulada
Una revisión sistemática y un metaanálisis"¿Existe una asociación entre el uso de fármacos antipsicóticos (FA) y las alteraciones de la homeostasis de la #glucosa? ➡️https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2837755
Una revisión sistemática y un metaanálisis"¿Existe una asociación entre el uso de fármacos antipsicóticos (FA) y las alteraciones de la homeostasis de la #glucosa? ➡️https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2837755
September 2, 2025 at 8:30 PM
⚠️ART. "Fármacos antipsicóticos y homeostasis de glucosa desregulada
Una revisión sistemática y un metaanálisis"¿Existe una asociación entre el uso de fármacos antipsicóticos (FA) y las alteraciones de la homeostasis de la #glucosa? ➡️https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2837755
Una revisión sistemática y un metaanálisis"¿Existe una asociación entre el uso de fármacos antipsicóticos (FA) y las alteraciones de la homeostasis de la #glucosa? ➡️https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2837755
Reposted
Exposición a antipsicóticos altera la homeostasis de la glucosa independientemente del tiempo de exposición, dosis, diagnóstico y propensión al aumento del peso #antipsychotics #glucose jamanetwork.com/journals/jam...
Antipsychotic Drugs and Dysregulated Glucose Homeostasis
This systematic review and meta-analysis examines the association between antipsychotic drug use and glucose homeostasis while considering weight gain propensity, medication type, and treatment durati...
jamanetwork.com
September 1, 2025 at 2:58 PM
Exposición a antipsicóticos altera la homeostasis de la glucosa independientemente del tiempo de exposición, dosis, diagnóstico y propensión al aumento del peso #antipsychotics #glucose jamanetwork.com/journals/jam...
Excited to share new work with #Margaret_Hahn #Emily_Smith #Mahavir_Agarwal #Christoph_Correll and collaborators. @jamapsychiatry.com
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Antipsychotic Drugs and Dysregulated Glucose Homeostasis
This systematic review and meta-analysis examines the association between antipsychotic drug use and glucose homeostasis while considering weight gain propensity, medication type, and treatment durati...
jamanetwork.com
August 27, 2025 at 9:20 PM
Excited to share new work with #Margaret_Hahn #Emily_Smith #Mahavir_Agarwal #Christoph_Correll and collaborators. @jamapsychiatry.com
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Thrilled to be part of an exciting new paper detailing work of the #Ernst_Strüngmann_Forum on #metabolic_neuropsychiatry providing new perspectives on roles of metabolism in brain and body and their therapeutic potential in #psychiatry
@ymilaneschi.bsky.social
t.co/CqsSNCPg4c
@ymilaneschi.bsky.social
t.co/CqsSNCPg4c
https://www.nature.com/articles/s44220-025-00422-6
t.co
June 26, 2025 at 11:13 PM
Thrilled to be part of an exciting new paper detailing work of the #Ernst_Strüngmann_Forum on #metabolic_neuropsychiatry providing new perspectives on roles of metabolism in brain and body and their therapeutic potential in #psychiatry
@ymilaneschi.bsky.social
t.co/CqsSNCPg4c
@ymilaneschi.bsky.social
t.co/CqsSNCPg4c
Reposted
In May 2024, I joined an inspiring week at the Ernst Strüngmann Forum on #Metabolic #Neuropsychiatry.
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Brain and body energy metabolism and potential for treatment of psychiatric disorders - Nature Mental Health
This Perspective highlights the important role of energy metabolism in psychiatric disorders and sets the groundwork for future studies in the emerging field of metabolic psychiatry.
www.nature.com
June 25, 2025 at 7:47 PM
In May 2024, I joined an inspiring week at the Ernst Strüngmann Forum on #Metabolic #Neuropsychiatry.
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Excited about our collaboration with #JillGlausier @thermofishersci.bsky.social and colleagues establishing volume electron microscopy approaches to map 3D synaptic nanoarchitecture in postmortem human prefrontal cortex in nanometer detail!
@cp-iscience.bsky.social
www.cell.com/iscience/ful...
@cp-iscience.bsky.social
www.cell.com/iscience/ful...
Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex
Neuroscience
www.cell.com
June 15, 2025 at 9:47 PM
Excited about our collaboration with #JillGlausier @thermofishersci.bsky.social and colleagues establishing volume electron microscopy approaches to map 3D synaptic nanoarchitecture in postmortem human prefrontal cortex in nanometer detail!
@cp-iscience.bsky.social
www.cell.com/iscience/ful...
@cp-iscience.bsky.social
www.cell.com/iscience/ful...
Reposted
We were honored to attend the 2025 Parkinson’s Disease Gordon Conference in Waterville Valley, NH. It was wonderful to bring together some of the best and brightest scientists to discuss the most exciting developments in PD research, including many of our own awardees and SAB members!
June 13, 2025 at 4:15 PM
We were honored to attend the 2025 Parkinson’s Disease Gordon Conference in Waterville Valley, NH. It was wonderful to bring together some of the best and brightest scientists to discuss the most exciting developments in PD research, including many of our own awardees and SAB members!
Reposted
Symposia submissions for #Dopamine2026 conference have been extended. You now have until Monday June 23rd to submit your abstract. dopaminesociety.org/abstract-sub...
June 13, 2025 at 10:08 PM
Symposia submissions for #Dopamine2026 conference have been extended. You now have until Monday June 23rd to submit your abstract. dopaminesociety.org/abstract-sub...
Reposted
Excited to share another piece of the chicken-or-egg puzzle: Investigating the Polygenic Relationship Between Cannabis Use and Schizophrenia in the All of Us Research Program
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Investigating the Polygenic Relationship Between Cannabis Use and Schizophrenia in the All of Us Research Program
Objective Decades of research have identified a strong association between heavy cannabis use and schizophrenia, with evidence of correlated genetic factors. However, many studies on the genetic relat...
www.medrxiv.org
May 25, 2025 at 3:26 PM
Excited to share another piece of the chicken-or-egg puzzle: Investigating the Polygenic Relationship Between Cannabis Use and Schizophrenia in the All of Us Research Program
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Reposted
Hello bluesky people from the Collaborative Computational Project for Electron cryo-Microscopy!
March 4, 2025 at 3:57 PM
Hello bluesky people from the Collaborative Computational Project for Electron cryo-Microscopy!
Excited about our new work led by @silasabuck.bsky.social & #SamMabry where we identified a new mechanism for both sex and regional differences in #dopamine neuron #mitochondria function in #aging and a #Parkinsons model in a #Drosophila model.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
dVGLUT Is a Mediator of Sex Differences in Dopamine Neuron Mitochondrial Function Across Aging and in a Parkinson's Disease Model
We examined sex and regional differences in mitochondrial reactive oxygen species (ROS) generation and their implications for dopamine (DA) neuron resilience using the Drosophila model. We found: (1)...
onlinelibrary.wiley.com
May 13, 2025 at 1:59 AM
Excited about our new work led by @silasabuck.bsky.social & #SamMabry where we identified a new mechanism for both sex and regional differences in #dopamine neuron #mitochondria function in #aging and a #Parkinsons model in a #Drosophila model.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted
🧠✨ Symposia submissions are NOW OPEN for Dopamine Meeting 2026! @DopamineSociety
📍Sevilla, Spain
📅 Open: May 1, 2025
⏳ Deadline: June 16, 2025
Spread the word — don’t miss out!
#Dopamine2026
dopaminesociety.org
📍Sevilla, Spain
📅 Open: May 1, 2025
⏳ Deadline: June 16, 2025
Spread the word — don’t miss out!
#Dopamine2026
dopaminesociety.org
May 2, 2025 at 12:23 PM
🧠✨ Symposia submissions are NOW OPEN for Dopamine Meeting 2026! @DopamineSociety
📍Sevilla, Spain
📅 Open: May 1, 2025
⏳ Deadline: June 16, 2025
Spread the word — don’t miss out!
#Dopamine2026
dopaminesociety.org
📍Sevilla, Spain
📅 Open: May 1, 2025
⏳ Deadline: June 16, 2025
Spread the word — don’t miss out!
#Dopamine2026
dopaminesociety.org
Reposted
First paper from the lab! We investigated the composition of synaptic vesicles that store fast glutamate or modulatory monoamines. Found distinct composition that affects the regulation of fusion.
Synaptic vesicles that store monoamines and glutamate differ in protein composition. https://www.biorxiv.org/content/10.1101/2025.05.06.651945v1
May 7, 2025 at 3:18 PM
First paper from the lab! We investigated the composition of synaptic vesicles that store fast glutamate or modulatory monoamines. Found distinct composition that affects the regulation of fusion.
Reposted
Out now: our preprint with Zach Freyberg, Jiying Ning and Jill Glausier on in situ cryoET of diverse brain tissues (www.biorxiv.org/content/10.1...), featuring a novel approach for preparing lamellae and the use of the CCP-EM framework for subtomogram averaging.
Uncovering synaptic and cellular nanoarchitecture of brain tissue via seamless in situ trimming and milling for cryo-electron tomography
Cell-cell communication underlies all emergent properties of the brain, including cognition, learning and memory. The physical basis for these communications is the synapse, a multi-component structur...
www.biorxiv.org
March 13, 2025 at 2:05 PM
Out now: our preprint with Zach Freyberg, Jiying Ning and Jill Glausier on in situ cryoET of diverse brain tissues (www.biorxiv.org/content/10.1...), featuring a novel approach for preparing lamellae and the use of the CCP-EM framework for subtomogram averaging.
So excited to share new work developed by #JiyingNing and #JillGlausier together w/ great collaborators #CCP-EM and others allowing us to #cryoET image 3D architecture of synapses and neuron-glia contacts directly in mouse, monkey, & human brain via SISTM!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Uncovering synaptic and cellular nanoarchitecture of brain tissue via seamless in situ trimming and milling for cryo-electron tomography
Cell-cell communication underlies all emergent properties of the brain, including cognition, learning and memory. The physical basis for these communications is the synapse, a multi-component structur...
www.biorxiv.org
March 13, 2025 at 12:59 AM
So excited to share new work developed by #JiyingNing and #JillGlausier together w/ great collaborators #CCP-EM and others allowing us to #cryoET image 3D architecture of synapses and neuron-glia contacts directly in mouse, monkey, & human brain via SISTM!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...