Leslie B Vosshall PhD
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leslievosshall.bsky.social
Leslie B Vosshall PhD
@leslievosshall.bsky.social
VP/CSO @HHMI.bsky.social & Head of #VosshallLab @rockefelleruniv Toward Excellent, Inclusive, & Open Science
Reposted by Leslie B Vosshall PhD
Researchers in the Vosshall lab have discovered the first evidence of what happens when a female mosquito chooses to mate for the one and only time in her life.

We spoke to @leslievosshall.bsky.social and @leahhouri.bsky.social about their unexpected findings. See the full Q&A:
What we got wrong about mosquito mating - News
Researchers have discovered the first evidence of what happens when a female mosquito chooses to mate for the one and only time in her life.
www.rockefeller.edu
November 10, 2025 at 7:51 PM
Reposted by Leslie B Vosshall PhD
Excellent work! I'm in support of any move away from the grotesque publishing model and journal profiteering we currently have, but how are we going to get institutional promotions/recruitment panels, funding bodies, grant peer reviewers etc to recognise it in their decision making?
November 6, 2025 at 5:49 PM
Reposted by Leslie B Vosshall PhD
IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇
November 6, 2025 at 2:49 PM
Reposted by Leslie B Vosshall PhD
Do we really still need scientific journals when BiorXiv + the community + q.e.d. evaluate, filter and provide constructive feedback on a #preprint in order to strengthen and improve the message?

#IMHO, this is really a question worth asking.
November 7, 2025 at 8:51 AM
Reposted by Leslie B Vosshall PhD
Reposted by Leslie B Vosshall PhD
This has always seemed to me to be an obvious no-brainer. Journals controlling the review process is such a hangover from Victorian gentlemen's clubs, and it feels that great papers get published *in spite* of the system, rather than because of it.
November 8, 2025 at 8:08 AM
Reposted by Leslie B Vosshall PhD
The idea is to decouple the journals from the review step. They’ll still exist, but they’ll need to add other value. They’ll highlight, curate, add new perspectives. If they do a good job they can still be prestigious (like Scientific American or Wired) (1.2) 👇
November 8, 2025 at 6:02 AM
Reposted by Leslie B Vosshall PhD
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸

There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell types and widespread co-expres...
www.cell.com
October 30, 2025 at 4:05 PM
Reposted by Leslie B Vosshall PhD
🦟 We've just published the world's first head-to-toe single-cell atlas of the Aedes aegypti mosquito in @cp-cell.bsky.social!
The #MosquitoCellAtlas maps 69 cell types across 19 tissues, revealing surprising biology. Read it here:
shorturl.at/dJWT3
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell types and widespread co-expres...
www.cell.com
October 30, 2025 at 3:28 PM
Reposted by Leslie B Vosshall PhD
A global effort, led by @leslievosshall.bsky.social and @nadavshai.bsky.social, just made the most dangerous animal in the world a lot easier to study—and perhaps defeat one day.

Learn more about the first head-to-toe cellular atlas of the mosquito, published in @cellpress.bsky.social, below.
Researchers release the world’s first head-to-toe cellular atlas of the mosquito - News
The atlas makes the most dangerous animal in the world a lot easier to study—and perhaps defeat one day.
www.rockefeller.edu
October 30, 2025 at 4:25 PM
Reposted by Leslie B Vosshall PhD
How does life evolve to adapt to modern cities?

Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.

🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515
Ancient origin of an urban underground mosquito
Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. In this work, we investigate a widely cited example of urban adaptation, Culex pipie...
www.science.org
October 25, 2025 at 4:46 AM
Reposted by Leslie B Vosshall PhD
Q.E.D works amazingly well! I was a skeptic at the beginning and then just really really impressed. For change 🥂
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 10:09 PM
Reposted by Leslie B Vosshall PhD
Congratulations @karalmckinley.bsky.social & lab on their groundbreaking recent preprint establishing + characterizing a chemically inducible model of menstruation in mouse:

www.biorxiv.org/content/10.1...

My jaw dropped when I heard this presented earlier this year. Incredible.
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 9, 2025 at 10:59 PM
Reposted by Leslie B Vosshall PhD
New
@currentbiology.bsky.social paper from @leslievosshall.bsky.social&@leahhouri.bsky.social: FEMALE mosquitoes control mating, not males, by special genital movement. No elongation = no mating! Plus: male asian tiger mosquitoes can bypass the yellow fever mosquito female control shorturl.at/tsIWH
A rapidly evolving female-controlled lock-and-key mechanism determines Aedes mosquito mating success
Houri-Zeevi et al. uncover a lock-and-key mating system in mosquitoes, where females control mating through genital responses to rapidly evolving male structures. Males of the invasive Asian tiger mos...
www.cell.com
October 28, 2025 at 7:56 PM
Reposted by Leslie B Vosshall PhD
The first detailed look at how mosquitoes mate from @leslievosshall.bsky.social's lab reverses the assumption that male mosquitoes control the process, finding that a subtle female behavior dictates whether mating will take place or not. @currentbiology.bsky.social

More here: https://bit.ly/4huwEpL
October 28, 2025 at 4:23 PM
Reposted by Leslie B Vosshall PhD
Ed Yong’s book AN IMMENSE WORLD, which is all about animals and their senses, was revelatory for me in talking about how what we define as a problem depends entirely on what environment we’ve chosen to set up for people to navigate.
October 9, 2025 at 9:22 PM
Great Job - Great Colleagues - Great Science👍
Help us pick the next generation of @hhmi.org Investigators, Freeman Hrabowski Scholars, Hanna Gray Fellows, Gilliam Fellows
Relocation to DC is required, perfect for academic PIs looking for their next chapter
hhmi.wd1.myworkdayjobs.com/External/job...
Senior Director - Scientific Officer
Primary Work Address: 4000 Jones Bridge Road, Chevy Chase, MD, 20815 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the disco...
hhmi.wd1.myworkdayjobs.com
October 9, 2025 at 9:48 PM
Reposted by Leslie B Vosshall PhD
Super-impressive - I’ve seen this peer review training in action. Something other institutions should replicate prereview.org/clubs/hhmi-t...
July 2, 2025 at 12:15 PM
Reposted by Leslie B Vosshall PhD
Very proud husband moment: my wife just pulled off a rare double, 2025 HHMI Freeman Hrabowski and McKnight Scholar! 🎉 Huge congrats as well to my colleagues Elisa and Sergey. A big moment for @ucd-physiology.bsky.social

While they prep the party, we’re heading off to celebrate in Barbados! 🎉🏖️🐬
June 19, 2025 at 6:36 PM
Reposted by Leslie B Vosshall PhD
Wow, HHMI and McKnight back-to-back!! Couldn't be any prouder of you @doctheagrif.bsky.social!! Happy Juneteenth
June 19, 2025 at 5:19 PM
Reposted by Leslie B Vosshall PhD
Congratulations to all the amazing scientists named 2025 Freeman Hrabowski Scholars by HHMI. We’re immensely honored to have two #PMB faculty members, @doctheagrif.bsky.social and @elisazhang.bsky.social , among this inspiring group. An incredible and well-deserved achievement! @ucdavis.bsky.social
The 2025 Freeman Hrabowski Scholars | HHMI
Freeman Hrabowski Scholars are outstanding early career faculty who have the potential to become leaders in their research fields.
www.hhmi.org
June 19, 2025 at 6:10 AM
Reposted by Leslie B Vosshall PhD
So stoked to see such amazing scientists and such amazing science in the HHMI Freeman-Hrabowski cohort. But in particular I am just so so so incredibly happy to be able to publicly celebrate the success of @alisonfeder.bsky.social! Go, Alison, go! www.hhmi.org/programs/fre...
The 2025 Freeman Hrabowski Scholars | HHMI
Freeman Hrabowski Scholars are outstanding early career faculty who have the potential to become leaders in their research fields.
www.hhmi.org
June 18, 2025 at 5:39 PM
Reposted by Leslie B Vosshall PhD
I’m thrilled to have been selected as an HHMI Freeman Hrabowski Scholar, along with my wonderful #PMB colleague @doctheagrif.bsky.social Excited for what’s to come - we’re just getting started! 🚀 @ucdavis.bsky.social
@ucd-physiology.bsky.social

health.ucdavis.edu/news/headlin...
UC Davis researchers honored by McKnight and Howard Hughes Medical Institute
UC Davis faculty Sergey Stavisky, Theanne Griffith and Elisa Zhang receive prestigious early-career recognition from McKnight Endowment Fund and the Howard Hughes Medical Institute.
health.ucdavis.edu
June 19, 2025 at 6:26 PM
Reposted by Leslie B Vosshall PhD
I’m so honored to be selected as both a 2025 McKnight Scholar and 2025 HHMI Freeman Hrabowski Scholar. And I couldn’t be prouder to share these honors with awesome @ucdavis.bsky.social colleagues 💙💛💙💛

health.ucdavis.edu/news/headlin...
UC Davis researchers honored by McKnight and Howard Hughes Medical Institute
UC Davis faculty Sergey Stavisky, Theanne Griffith and Elisa Zhang receive prestigious early-career recognition from McKnight Endowment Fund and the Howard Hughes Medical Institute.
health.ucdavis.edu
June 19, 2025 at 4:46 PM
Reposted by Leslie B Vosshall PhD
I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness.
www.kpbs.org/podcasts/kpb...
Nobel laureate on how Trump's cuts are hurting science
Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researche...
www.kpbs.org
June 19, 2025 at 12:27 AM