Yttri Lab
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yttrilab.bsky.social
Yttri Lab
@yttrilab.bsky.social
120 followers 53 following 13 posts
Interrogating the functional interactions of motor and decision circuits that lead to behavior

https://labs.bio.cmu.edu/yttri/
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yttrilab.bsky.social
I hope this new-ish paper will challenge people to think about the interpretations of our models
STRIATUM SUPPORTS REINFORCEMENT AND NOT ACTION SELECTION (!!!)
tinyurl.com/HodgeAndYttri

@cmuscience.bsky.social
@cmu-neuroscience.bsky.social
#neuroskyence
Striatal modulation supports context-specific reinforcement and not action selection
Hodge et al. used closed-loop optogenetic stimulation and naturalistic behaviors to determine that striatal activity does not select the action to perform but rather biases performance through reinfor...
tinyurl.com
November 14, 2025 at 3:10 PM
yttrilab.bsky.social
In an effort to bring #neuroskyence to @bsky.app I wanted to share our recent paper in Neuron
tinyurl.com/LesionsOfM1
@markolas.bsky.social and I asked what forelimb M1 contributes to striatal and behavioral dynamics using joystick tasks and CFA lesions
@cmuscience.bsky.social @the-cnbc.bsky.social
Motor cortex is responsible for motoric dynamics in striatum and the execution of both skilled and unskilled actions
Nicholas and Yttri find that in the absence of motor cortex, the stratum alone is not capable of producing goal-directed behavior. Lesions of motor cortex also produce a freezing of gait-like behavior...
tinyurl.com
February 12, 2025 at 10:06 PM