We got some help from Brian Burke & @ylleecellbio.bsky.social with a DN-KASH #nesprin construct, allowing us to sever the cytoskeleton from the LINC. Since these cells become osteogenic like WT MSCs, nuclear deformation is sufficient for confinement-induced #differentiation. (7/n)
May 29, 2025 at 2:48 AM
We got some help from Brian Burke & @ylleecellbio.bsky.social with a DN-KASH #nesprin construct, allowing us to sever the cytoskeleton from the LINC. Since these cells become osteogenic like WT MSCs, nuclear deformation is sufficient for confinement-induced #differentiation. (7/n)
I have confirmation from several sources now that all T32s, many F30s and F31s, and most or all Center awards (P30, P50) have been terminated at Columbia.
This is quite damaging to research and to individuals.
This is pure terrorism and cannot be legal. But litigation will take time...
March 11, 2025 at 2:30 PM
I have confirmation from several sources now that all T32s, many F30s and F31s, and most or all Center awards (P30, P50) have been terminated at Columbia.
This is quite damaging to research and to individuals.
This is pure terrorism and cannot be legal. But litigation will take time...