Andrew Holle
@ahcells.bsky.social
Confinement Mechanobiology Lab, Mechanobiology Institute | National University of Singapore
Pinned
Andrew Holle
@ahcells.bsky.social
· May 29
Confined Migration Drives Stem Cell Differentiation
Human mesenchymal stem cell (hMSC) homing to sites of regeneration requires navigation through mechanically confining extracellular matrix environments, inducing rapid and dramatic morphological adap...
advanced.onlinelibrary.wiley.com
Fresh science! Check out the Confinement Mechanobiology Lab's new paper on how confined migration can drive stem cell differentiation. Let’s do a thread! (1/n)
advanced.onlinelibrary.wiley.com/doi/full/10....
advanced.onlinelibrary.wiley.com/doi/full/10....
Interested in a #postdoc on nuclear #mechanobiology? We have a fully funded position in the Confinement Mechanobiology Lab designed to help you meet your career goals while researching the rapidly growing field of cellular #confinement. Please get in touch for more info!
June 24, 2025 at 3:48 AM
Interested in a #postdoc on nuclear #mechanobiology? We have a fully funded position in the Confinement Mechanobiology Lab designed to help you meet your career goals while researching the rapidly growing field of cellular #confinement. Please get in touch for more info!
There’s tons out there on fibroblast #mechanobiology in disease. In our new review in @aip-publishing.bsky.social, Yeji @cyj8.bsky.social gives the who/what/where/when/how/why of mechanosensitive fibroblast activation, from CAFs to FAFs and nearly everything in between!
pubs.aip.org/aip/apb/arti...
pubs.aip.org/aip/apb/arti...
The mechanobiology of fibroblast activation in disease
Fibroblasts play crucial roles in wound healing, cancer, and fibrosis. Many aspects of these roles are driven by the process known as fibroblast activation. The
pubs.aip.org
June 23, 2025 at 1:38 PM
There’s tons out there on fibroblast #mechanobiology in disease. In our new review in @aip-publishing.bsky.social, Yeji @cyj8.bsky.social gives the who/what/where/when/how/why of mechanosensitive fibroblast activation, from CAFs to FAFs and nearly everything in between!
pubs.aip.org/aip/apb/arti...
pubs.aip.org/aip/apb/arti...
Just a few days to submit for the Sep 9-12 @mbisg.bsky.social conference! Cool feature this year- a #HawkerCentre night with speakers and ECRs. Imagine enjoying Char Kway Teow & chatting #microtubules with someone like Sasha Bershadsky! Register here: www.mbi.nus.edu.sg/events/mbico...
May 29, 2025 at 3:06 AM
Just a few days to submit for the Sep 9-12 @mbisg.bsky.social conference! Cool feature this year- a #HawkerCentre night with speakers and ECRs. Imagine enjoying Char Kway Teow & chatting #microtubules with someone like Sasha Bershadsky! Register here: www.mbi.nus.edu.sg/events/mbico...
Fresh science! Check out the Confinement Mechanobiology Lab's new paper on how confined migration can drive stem cell differentiation. Let’s do a thread! (1/n)
advanced.onlinelibrary.wiley.com/doi/full/10....
advanced.onlinelibrary.wiley.com/doi/full/10....
Confined Migration Drives Stem Cell Differentiation
Human mesenchymal stem cell (hMSC) homing to sites of regeneration requires navigation through mechanically confining extracellular matrix environments, inducing rapid and dramatic morphological adap...
advanced.onlinelibrary.wiley.com
May 29, 2025 at 2:48 AM
Fresh science! Check out the Confinement Mechanobiology Lab's new paper on how confined migration can drive stem cell differentiation. Let’s do a thread! (1/n)
advanced.onlinelibrary.wiley.com/doi/full/10....
advanced.onlinelibrary.wiley.com/doi/full/10....
Three weeks left until the abstract submission deadline for our joint MBI-MPI #mechanobiology conference this September in Singapore!
To early career scientists- be sure to apply for a travel award to present your work! mbi.nus.edu.sg/events/mbico...
To early career scientists- be sure to apply for a travel award to present your work! mbi.nus.edu.sg/events/mbico...
May 8, 2025 at 7:43 AM
Three weeks left until the abstract submission deadline for our joint MBI-MPI #mechanobiology conference this September in Singapore!
To early career scientists- be sure to apply for a travel award to present your work! mbi.nus.edu.sg/events/mbico...
To early career scientists- be sure to apply for a travel award to present your work! mbi.nus.edu.sg/events/mbico...