Xujun Cao
@xujunc.bsky.social
🇸🇬 PhD Candidate in Chemistry @ Stanford studying the biochemistry of innate immunity.
Lingyin Li Lab (@lingyinli.bsky.social) @ Stanford University & Arc Institute
Feed is mostly food and papers I forget to read
Lingyin Li Lab (@lingyinli.bsky.social) @ Stanford University & Arc Institute
Feed is mostly food and papers I forget to read
It's been a long time coming, but so excited to see this finally out! We've a few more tricks up our sleeves in the design of inhibitors...🤔
The newest paper from the lab is now out @natchembio.nature.com! A hard-won effort by Rebecca and @xujunc.bsky.social uncovers a previously undescribed post-translationally modified site that regulates STING signaling and proposes a new strategy for inhibition.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cysteine allostery and autoinhibition govern human STING oligomer functionality - Nature Chemical Biology
Palmitoylation at C64 in stimulator of interferon genes (STING) is reported and, along with engagement of C91, is involved in dynamic cross talk with C148 to alter STING oligomer states and ultimately...
www.nature.com
July 4, 2025 at 9:06 PM
It's been a long time coming, but so excited to see this finally out! We've a few more tricks up our sleeves in the design of inhibitors...🤔
Reposted by Xujun Cao
Reposted by Xujun Cao
'The authors were aware they were treading on sensitive ground. “I hope that eight Italian authors is enough,” said Ivan Di Terlizzi, a statistical physicist at the Max Planck Institute for the Physics of Complex Systems in Dresden, Germany, who is originally from Puglia, Italy.'
The Perfect Cacio e Pepe Recipe, According to Science
Italian scientists have drawn from thermodynamic principles to prevent a famous pasta from turning into a gooey mess.
www.nytimes.com
January 25, 2025 at 11:20 PM
'The authors were aware they were treading on sensitive ground. “I hope that eight Italian authors is enough,” said Ivan Di Terlizzi, a statistical physicist at the Max Planck Institute for the Physics of Complex Systems in Dresden, Germany, who is originally from Puglia, Italy.'
Reposted by Xujun Cao
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets
Refreshing to see papers that go to great pains to set the record straight being published in a high profile setting
Refreshing to see papers that go to great pains to set the record straight being published in a high profile setting
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets - Nature Communications
Autophagosome tethering compounds (ATTECs) are small molecule degraders hijacking the autophagy system. Here, the authors show that current ATTEC ligands did not bind to their designated targets but e...
www.nature.com
November 29, 2024 at 12:39 PM
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets
Refreshing to see papers that go to great pains to set the record straight being published in a high profile setting
Refreshing to see papers that go to great pains to set the record straight being published in a high profile setting
Reposted by Xujun Cao
Content over at the other site deleted; but apart from #KanyeOrCronin or #SocialIsolationSocial posts, I think this was my greatest contribution there, so for a bit of Friday fun for #Chemsky, I'm reposting it here:
Taylor Swift as @naturechemistry.bsky.social covers, starting with March 2020:
Taylor Swift as @naturechemistry.bsky.social covers, starting with March 2020:
November 29, 2024 at 6:32 PM
Content over at the other site deleted; but apart from #KanyeOrCronin or #SocialIsolationSocial posts, I think this was my greatest contribution there, so for a bit of Friday fun for #Chemsky, I'm reposting it here:
Taylor Swift as @naturechemistry.bsky.social covers, starting with March 2020:
Taylor Swift as @naturechemistry.bsky.social covers, starting with March 2020:
Reposted by Xujun Cao
A poem for my last day working at the writing center for the semester (by Joseph Fasano)
November 23, 2024 at 2:09 AM
A poem for my last day working at the writing center for the semester (by Joseph Fasano)
Reposted by Xujun Cao
Idea for a crime novel. Someone sets up a starter pack and each name on there are killed off one by one. The remaining people have to team up to work out who the killer is. 💙📚 #booksky
November 18, 2024 at 12:49 PM
Idea for a crime novel. Someone sets up a starter pack and each name on there are killed off one by one. The remaining people have to team up to work out who the killer is. 💙📚 #booksky
Reposted by Xujun Cao
📯📯 Chemical Biology starter pack 📯📯
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
November 17, 2024 at 10:58 PM
📯📯 Chemical Biology starter pack 📯📯
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
Every now and then your science keeps you humble by looking like that Sodom and Gomorrah painting
November 17, 2024 at 3:36 AM
Every now and then your science keeps you humble by looking like that Sodom and Gomorrah painting
Joining the #ChemistsWhoCook community here. Inspired by an ice cream I had at Ahn's Dry Cleaning in SD, this is a Dark Chocolate Wasabi Cookie that I had ChatGPT come up with the recipe for.
November 17, 2024 at 3:24 AM
Joining the #ChemistsWhoCook community here. Inspired by an ice cream I had at Ahn's Dry Cleaning in SD, this is a Dark Chocolate Wasabi Cookie that I had ChatGPT come up with the recipe for.
Reposted by Xujun Cao
Shots fired.
Leaving Twitter? Here are some alternatives to checking an online Nazi bot sewer every 20 minutes | First Dog on the Moon
Plant a tomato bush then lecture it on how it should grow tomatoes
www.theguardian.com
November 15, 2024 at 6:39 AM
Shots fired.