Xavier
xaviervel.bsky.social
Xavier
@xaviervel.bsky.social
Nephrologist at the UMass Chan School of Medicine.
Their presentation was great and fun to see. Congrats to the winners.
April 12, 2025 at 10:11 PM
On it
March 5, 2025 at 9:31 PM
I think this is where I first learned about it.
March 5, 2025 at 7:47 PM
Reposted by Xavier
It turns out, that under the right conditions, carbonyl groups form on MPO. Hydralazine actually ATTACHES to these carbonyl groups, probably modifying the MPO conformation and inducing a neo-antigen, which eventually causes the formation of anti-MPO IgM!
March 4, 2025 at 9:19 PM
Reposted by Xavier
Most SEs from steroids are longer term and cumulative, aside from infection. I don’t know of many folks that would rx a CNI first.
March 1, 2025 at 2:38 AM
Reposted by Xavier
Steroid if it’s their first or second go, if frequently relapsing go next to CNI, then if breaking through CNI and prednisone it’s RTX
March 1, 2025 at 2:22 AM
Do you have any particular concerns for steroid-related side effects? Or do you always chose steroids as first line?
March 1, 2025 at 2:33 AM