Jacob Wolfe
@wolfepackscience.bsky.social
Passionate About Peptide Chemistry, Enzyme Structure/Design, and Accessible Science 🧪
Nice Jewish Boy ✡️
Pitt Biophysics PhD Candidate - Anticipated Graduation August 2025 🎓
2023-2024 Mellon Predoctoral Fellow in Seth Horne's Lab 👨🔬
Nice Jewish Boy ✡️
Pitt Biophysics PhD Candidate - Anticipated Graduation August 2025 🎓
2023-2024 Mellon Predoctoral Fellow in Seth Horne's Lab 👨🔬
It's the American Peptide Society Conference, this character limit is rough.
aps2025.org
aps2025.org
APS2025 – Peptides Rising
aps2025.org
June 3, 2025 at 7:36 PM
It's the American Peptide Society Conference, this character limit is rough.
aps2025.org
aps2025.org
Not to shamelessly self-promote, but this first article in the series goes into a little more depth on the topic. It's cited in the new one but I'll leave it here too 🙂https://www.linkedin.com/pulse/alphafold3-best-practices-how-analyze-interpret-af3-jacob-wolfe-5eute
March 24, 2025 at 5:38 PM
Not to shamelessly self-promote, but this first article in the series goes into a little more depth on the topic. It's cited in the new one but I'll leave it here too 🙂https://www.linkedin.com/pulse/alphafold3-best-practices-how-analyze-interpret-af3-jacob-wolfe-5eute
Excellent question! So the term "peptide" is defined by sequence length generally <50 aa's, regardless of structure. Miniproteins have a discreet tertiary folded structure, so they can place sidechains in 3D space more like a protein and less like a peptide flexible. pubs.acs.org/doi/full/10....
Miniprotein Design: Past, Present, and Prospects
ConspectusThe design and study of miniproteins, that is, polypeptide chains <40 amino acids in length that adopt defined and stable 3D structures, is resurgent. Miniproteins offer possibilities for re...
pubs.acs.org
March 12, 2025 at 6:45 PM
Excellent question! So the term "peptide" is defined by sequence length generally <50 aa's, regardless of structure. Miniproteins have a discreet tertiary folded structure, so they can place sidechains in 3D space more like a protein and less like a peptide flexible. pubs.acs.org/doi/full/10....
February 8, 2025 at 3:08 PM
Just thought about Steve Mayo as well www.bbe.caltech.edu/people/steph...
Stephen L. (Steve) Mayo
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Biology and Biological Engineering
www.bbe.caltech.edu
February 3, 2025 at 2:07 AM
Just thought about Steve Mayo as well www.bbe.caltech.edu/people/steph...
Squire Booker was probably already on your list :) sites.psu.edu/sjbookerlab/...
Squire J. Booker – WELCOME TO THE BOOKER LABORATORY
sites.psu.edu
February 2, 2025 at 6:47 PM
Squire Booker was probably already on your list :) sites.psu.edu/sjbookerlab/...
@blackinbiophys.bsky.social If you're looking for researchers with a good social media presence (and if Biophysicists are chemists -definitely depends on who you ask)
February 2, 2025 at 6:46 PM
@blackinbiophys.bsky.social If you're looking for researchers with a good social media presence (and if Biophysicists are chemists -definitely depends on who you ask)
So like, if I write something and use ChatGPT to edit it for like grammar and punctuation like I would use MicrosoftWord that's not protected?
I've run that through one of those "Is this AI generated?" checkers before and it gives a low confidence that it is
I've run that through one of those "Is this AI generated?" checkers before and it gives a low confidence that it is
February 2, 2025 at 12:45 AM
So like, if I write something and use ChatGPT to edit it for like grammar and punctuation like I would use MicrosoftWord that's not protected?
I've run that through one of those "Is this AI generated?" checkers before and it gives a low confidence that it is
I've run that through one of those "Is this AI generated?" checkers before and it gives a low confidence that it is