WIMI Biotech
@wimi-bio-tech.bsky.social
The Chinese name of "WIIMI" is"未米", which means "the future crops".
WIMI Service Items: Genetic Transformation & Vector Construction
sales@wimibiotech.com
WIMI Service Items: Genetic Transformation & Vector Construction
sales@wimibiotech.com
🎉🐴 Happy Chinese New Year 2026 from WIMI Biotech! Wishing everyone a prosperous Year of the Horse filled with success and good fortune!
Our office will be on Spring Festival holiday from Feb 15 – Feb 23. Sample intake resumes: Feb 24 (正月初八)📞 Service enquiries remain available throughout the holiday!
Our office will be on Spring Festival holiday from Feb 15 – Feb 23. Sample intake resumes: Feb 24 (正月初八)📞 Service enquiries remain available throughout the holiday!
February 14, 2026 at 4:42 PM
🎉🐴 Happy Chinese New Year 2026 from WIMI Biotech! Wishing everyone a prosperous Year of the Horse filled with success and good fortune!
Our office will be on Spring Festival holiday from Feb 15 – Feb 23. Sample intake resumes: Feb 24 (正月初八)📞 Service enquiries remain available throughout the holiday!
Our office will be on Spring Festival holiday from Feb 15 – Feb 23. Sample intake resumes: Feb 24 (正月初八)📞 Service enquiries remain available throughout the holiday!
🍅 Major breakthrough in crop disease resistance! Dr. Zhou Shaoqun's team at CAAS-SZAIGR has decoded the early infection mechanisms of late blight — one of the world's most devastating crop diseases costing $10B+/year in losses.
academic.oup.com/plphys/advan...
#PlantScience #LateBlight #CRISPR
academic.oup.com/plphys/advan...
#PlantScience #LateBlight #CRISPR
February 14, 2026 at 4:05 PM
🍅 Major breakthrough in crop disease resistance! Dr. Zhou Shaoqun's team at CAAS-SZAIGR has decoded the early infection mechanisms of late blight — one of the world's most devastating crop diseases costing $10B+/year in losses.
academic.oup.com/plphys/advan...
#PlantScience #LateBlight #CRISPR
academic.oup.com/plphys/advan...
#PlantScience #LateBlight #CRISPR
🌾 Groundbreaking discovery in plant biology! Prof. Yan Changjie's team (Yangzhou Univ.) collaborating with Academician Zhang Qifa & Prof. Ouyang Yidan (HZAU) has cracked the evolutionary code of Gγ protein "tails" in crops!
Read more:
doi.org/10.1093/plce...
#CRISPR #CropScience #GProtein
Read more:
doi.org/10.1093/plce...
#CRISPR #CropScience #GProtein
February 14, 2026 at 3:49 PM
🌾 Groundbreaking discovery in plant biology! Prof. Yan Changjie's team (Yangzhou Univ.) collaborating with Academician Zhang Qifa & Prof. Ouyang Yidan (HZAU) has cracked the evolutionary code of Gγ protein "tails" in crops!
Read more:
doi.org/10.1093/plce...
#CRISPR #CropScience #GProtein
Read more:
doi.org/10.1093/plce...
#CRISPR #CropScience #GProtein
🚀 HUGE news from WIMI Biotech! Our proprietary gene-editing tool CasY7-WM01 has just received TWO biosafety certificates for maize — making us the #1 biotech company in China for maize gene-editing safety certifications!
#CRISPR #GeneEditing#FoodSecurity #Maize #SeedIndustry #CasY7 #Innovation
#CRISPR #GeneEditing#FoodSecurity #Maize #SeedIndustry #CasY7 #Innovation
February 14, 2026 at 3:44 PM
🚀 HUGE news from WIMI Biotech! Our proprietary gene-editing tool CasY7-WM01 has just received TWO biosafety certificates for maize — making us the #1 biotech company in China for maize gene-editing safety certifications!
#CRISPR #GeneEditing#FoodSecurity #Maize #SeedIndustry #CasY7 #Innovation
#CRISPR #GeneEditing#FoodSecurity #Maize #SeedIndustry #CasY7 #Innovation
🌽 New research breakthrough in drought-resistant crops! Prof. Guan Shuyan's team at Jilin Agricultural University has identified Zm4CL2 — a key gene that enhances maize drought tolerance through a dual mechanism.
Read more:
sciencedirect.com/science/arti...
#DroughtTolerance #Maize#CropScience
Read more:
sciencedirect.com/science/arti...
#DroughtTolerance #Maize#CropScience
February 13, 2026 at 9:10 AM
🌽 New research breakthrough in drought-resistant crops! Prof. Guan Shuyan's team at Jilin Agricultural University has identified Zm4CL2 — a key gene that enhances maize drought tolerance through a dual mechanism.
Read more:
sciencedirect.com/science/arti...
#DroughtTolerance #Maize#CropScience
Read more:
sciencedirect.com/science/arti...
#DroughtTolerance #Maize#CropScience
🌽 Exciting research breakthrough! Prof. Yan Jianbing's team at HZAU has identified gene ZmTPK2 — a metabolic hub that simultaneously boosts maize yield AND protein content, overcoming the long-standing trade-off in crop breeding.
Read more:
www.nature.com/articles/s41...
#NatureCommunications #Crop
Read more:
www.nature.com/articles/s41...
#NatureCommunications #Crop
February 13, 2026 at 8:55 AM
🌽 Exciting research breakthrough! Prof. Yan Jianbing's team at HZAU has identified gene ZmTPK2 — a metabolic hub that simultaneously boosts maize yield AND protein content, overcoming the long-standing trade-off in crop breeding.
Read more:
www.nature.com/articles/s41...
#NatureCommunications #Crop
Read more:
www.nature.com/articles/s41...
#NatureCommunications #Crop
Plants counter with NLRs R2 & Rpi-mcq1, which guard both the pH regulator (StATP6V1C1) and its downstream target — a dual-layer decoy surveillance system.
A new arms race battlefield: intracellular pH homeostasis.
#PlantImmunity #Oomycete #LateBlight #PlantPathology
A new arms race battlefield: intracellular pH homeostasis.
#PlantImmunity #Oomycete #LateBlight #PlantPathology
February 13, 2026 at 7:39 AM
Plants counter with NLRs R2 & Rpi-mcq1, which guard both the pH regulator (StATP6V1C1) and its downstream target — a dual-layer decoy surveillance system.
A new arms race battlefield: intracellular pH homeostasis.
#PlantImmunity #Oomycete #LateBlight #PlantPathology
A new arms race battlefield: intracellular pH homeostasis.
#PlantImmunity #Oomycete #LateBlight #PlantPathology
Phytophthora infestans deploys two RxLR effectors — AL3 & Avr2 — that sequentially manipulate intracellular pH in opposite directions via V-ATPase, creating optimal conditions to exploit host susceptibility factor StBSL1 at each stage of infection.
📄 Xue et al. 2026 | DOI: 10.1186/s43897-025-00184-w
📄 Xue et al. 2026 | DOI: 10.1186/s43897-025-00184-w
February 13, 2026 at 7:39 AM
Phytophthora infestans deploys two RxLR effectors — AL3 & Avr2 — that sequentially manipulate intracellular pH in opposite directions via V-ATPase, creating optimal conditions to exploit host susceptibility factor StBSL1 at each stage of infection.
📄 Xue et al. 2026 | DOI: 10.1186/s43897-025-00184-w
📄 Xue et al. 2026 | DOI: 10.1186/s43897-025-00184-w
🏆 Proud to announce that WIMI Biotech (Qingdao) has been awarded the First Prize in Engineering & Technology Research at the 2025 Ministry of Education Outstanding Scientific Research Achievement Award!
#AgTech #Genomics #Biotech #Innovation #MaizeBreeding #China
#AgTech #Genomics #Biotech #Innovation #MaizeBreeding #China
February 12, 2026 at 9:19 AM
🏆 Proud to announce that WIMI Biotech (Qingdao) has been awarded the First Prize in Engineering & Technology Research at the 2025 Ministry of Education Outstanding Scientific Research Achievement Award!
#AgTech #Genomics #Biotech #Innovation #MaizeBreeding #China
#AgTech #Genomics #Biotech #Innovation #MaizeBreeding #China
Experimental validation proves the power of AI:
Our synthetic enhancers achieved an 11.4x higher success rate than traditional methods. The top performer, STEsyn3578, reached an activity level of 64.5x—surpassing its natural counterpart by 2.27x and breaking the limits of natural evolution. 🚀🧬
Our synthetic enhancers achieved an 11.4x higher success rate than traditional methods. The top performer, STEsyn3578, reached an activity level of 64.5x—surpassing its natural counterpart by 2.27x and breaking the limits of natural evolution. 🚀🧬
February 12, 2026 at 8:40 AM
Experimental validation proves the power of AI:
Our synthetic enhancers achieved an 11.4x higher success rate than traditional methods. The top performer, STEsyn3578, reached an activity level of 64.5x—surpassing its natural counterpart by 2.27x and breaking the limits of natural evolution. 🚀🧬
Our synthetic enhancers achieved an 11.4x higher success rate than traditional methods. The top performer, STEsyn3578, reached an activity level of 64.5x—surpassing its natural counterpart by 2.27x and breaking the limits of natural evolution. 🚀🧬
🚀 AI vs. Sequence Space:Designing a 60-bp enhancer means navigating 1.33 × 10^36 possibilities. BaseSearch AI solves this!
Efficiency: Boosted by 27.8% via evolutionary strategies.
Results: 5,000 synthetic enhancers designed "on-demand." Impact: Moving beyond nature to engineer the future of crops.
Efficiency: Boosted by 27.8% via evolutionary strategies.
Results: 5,000 synthetic enhancers designed "on-demand." Impact: Moving beyond nature to engineer the future of crops.
February 12, 2026 at 8:40 AM
🚀 AI vs. Sequence Space:Designing a 60-bp enhancer means navigating 1.33 × 10^36 possibilities. BaseSearch AI solves this!
Efficiency: Boosted by 27.8% via evolutionary strategies.
Results: 5,000 synthetic enhancers designed "on-demand." Impact: Moving beyond nature to engineer the future of crops.
Efficiency: Boosted by 27.8% via evolutionary strategies.
Results: 5,000 synthetic enhancers designed "on-demand." Impact: Moving beyond nature to engineer the future of crops.
Platform: STEM-seq for high-throughput, position-independent screening.
Scale: 81,475 elements screened; 6,904 functional STEs identified.
Precision: At just 60-80 bp, these enhancers are ideal "genetic switches" for CRISPR editing in major crops like maize, wheat, and soybean. 🚀
Scale: 81,475 elements screened; 6,904 functional STEs identified.
Precision: At just 60-80 bp, these enhancers are ideal "genetic switches" for CRISPR editing in major crops like maize, wheat, and soybean. 🚀
February 12, 2026 at 8:40 AM
Platform: STEM-seq for high-throughput, position-independent screening.
Scale: 81,475 elements screened; 6,904 functional STEs identified.
Precision: At just 60-80 bp, these enhancers are ideal "genetic switches" for CRISPR editing in major crops like maize, wheat, and soybean. 🚀
Scale: 81,475 elements screened; 6,904 functional STEs identified.
Precision: At just 60-80 bp, these enhancers are ideal "genetic switches" for CRISPR editing in major crops like maize, wheat, and soybean. 🚀
🚀 WIMI Biotech & SJTU breakthrough in Advanced Science!
We’ve bridged the gap from "natural discovery" to "AI-guided design" for crop engineering.
🧵1/4
Read more:
advanced.onlinelibrary.wiley.com/.../advs.202...
#WimiBiotech #SJTU #AdvancedScience #AgTech #PlantBiology #AI #SyntheticBiology
We’ve bridged the gap from "natural discovery" to "AI-guided design" for crop engineering.
🧵1/4
Read more:
advanced.onlinelibrary.wiley.com/.../advs.202...
#WimiBiotech #SJTU #AdvancedScience #AgTech #PlantBiology #AI #SyntheticBiology
February 12, 2026 at 8:40 AM
🚀 WIMI Biotech & SJTU breakthrough in Advanced Science!
We’ve bridged the gap from "natural discovery" to "AI-guided design" for crop engineering.
🧵1/4
Read more:
advanced.onlinelibrary.wiley.com/.../advs.202...
#WimiBiotech #SJTU #AdvancedScience #AgTech #PlantBiology #AI #SyntheticBiology
We’ve bridged the gap from "natural discovery" to "AI-guided design" for crop engineering.
🧵1/4
Read more:
advanced.onlinelibrary.wiley.com/.../advs.202...
#WimiBiotech #SJTU #AdvancedScience #AgTech #PlantBiology #AI #SyntheticBiology
New therapeutic Adenine Base Editor (ABE) with minimized off-target effects! 🧬
A study in Protein&Cell by Erwei Zuo’s team introduces ABE8eY149V.
Read more: doi.org/10.1093/proc...
#GeneEditing #BaseEditing #Biotech #sciencenews
A study in Protein&Cell by Erwei Zuo’s team introduces ABE8eY149V.
Read more: doi.org/10.1093/proc...
#GeneEditing #BaseEditing #Biotech #sciencenews
February 11, 2026 at 3:10 AM
New therapeutic Adenine Base Editor (ABE) with minimized off-target effects! 🧬
A study in Protein&Cell by Erwei Zuo’s team introduces ABE8eY149V.
Read more: doi.org/10.1093/proc...
#GeneEditing #BaseEditing #Biotech #sciencenews
A study in Protein&Cell by Erwei Zuo’s team introduces ABE8eY149V.
Read more: doi.org/10.1093/proc...
#GeneEditing #BaseEditing #Biotech #sciencenews
Why L-theanine? It’s the "magic molecule" in tea that provides that unique umami flavor and calming effect. 🧘♂️ By precision-tuning the expression of biosynthetic enzymes, this study successfully increased theanine levels, paving the way for "Functional Tea" that tastes better and relaxes more. 🧬
February 10, 2026 at 3:07 AM
Why L-theanine? It’s the "magic molecule" in tea that provides that unique umami flavor and calming effect. 🧘♂️ By precision-tuning the expression of biosynthetic enzymes, this study successfully increased theanine levels, paving the way for "Functional Tea" that tastes better and relaxes more. 🧬
✂️ Researchers at CAAS are using CRISPR-Act—not as a scissor, but as a "volume knob"—to dial up the natural flavors of tea. By targeting the CsAlaDC and CsTSI genes simultaneously, they've unlocked a new way to supercharge tea plants. 🍵 #CRISPR
Read the full study:
academic.oup.com/.../doi/10.1...
Read the full study:
academic.oup.com/.../doi/10.1...
February 10, 2026 at 3:07 AM
✂️ Researchers at CAAS are using CRISPR-Act—not as a scissor, but as a "volume knob"—to dial up the natural flavors of tea. By targeting the CsAlaDC and CsTSI genes simultaneously, they've unlocked a new way to supercharge tea plants. 🍵 #CRISPR
Read the full study:
academic.oup.com/.../doi/10.1...
Read the full study:
academic.oup.com/.../doi/10.1...
Traditional Cas9 is often too "bulky" for AAV viral vectors, making delivery a bottleneck. ISCro4 is only 1/3 the size of Cas9, making it the perfect "micro-scalpel" for in vivo gene therapy. Smaller, sharper, and easier to deliver. The future of medicine is getting compact! 🚀 3/3
February 10, 2026 at 2:33 AM
Traditional Cas9 is often too "bulky" for AAV viral vectors, making delivery a bottleneck. ISCro4 is only 1/3 the size of Cas9, making it the perfect "micro-scalpel" for in vivo gene therapy. Smaller, sharper, and easier to deliver. The future of medicine is getting compact! 🚀 3/3
ISCro4 a game-changer? 1️⃣ Ancestor of Cas12: It’s a TnpB protein—the evolutionary predecessor to larger Cas enzymes. 2️⃣ Cryo-EM Precision: The team captured the system in pre- and post-cleavage states, revealing how it uses a small ωRNA to guide precise DNA cuts with just ~400 amino acids. 🔬 2/3
February 10, 2026 at 2:30 AM
ISCro4 a game-changer? 1️⃣ Ancestor of Cas12: It’s a TnpB protein—the evolutionary predecessor to larger Cas enzymes. 2️⃣ Cryo-EM Precision: The team captured the system in pre- and post-cleavage states, revealing how it uses a small ωRNA to guide precise DNA cuts with just ~400 amino acids. 🔬 2/3
Size matters in genome engineering! 📏 Martin Jinek and Gerald Schwank’s teams at UZH have unveiled the molecular blueprint of ISCro4 in Science Magazine.
This hypercompact TnpB nuclease is one of the smallest "genetic scissors" ever discovered. 🧬 #GeneEditing #Science #CRISPR 1/3
This hypercompact TnpB nuclease is one of the smallest "genetic scissors" ever discovered. 🧬 #GeneEditing #Science #CRISPR 1/3
February 10, 2026 at 2:27 AM
Size matters in genome engineering! 📏 Martin Jinek and Gerald Schwank’s teams at UZH have unveiled the molecular blueprint of ISCro4 in Science Magazine.
This hypercompact TnpB nuclease is one of the smallest "genetic scissors" ever discovered. 🧬 #GeneEditing #Science #CRISPR 1/3
This hypercompact TnpB nuclease is one of the smallest "genetic scissors" ever discovered. 🧬 #GeneEditing #Science #CRISPR 1/3
Bridging the Gap from Lab Discovery to Field Reality 🌾🧪
At Wimi Biotech, we don't just stop at a successful edit in the lab. Our mission is to see those genetic breakthroughs thrive where they belong—in the field.
#WimiBiotech #AgTech #FieldTrials #PlantScience #CropImprovement #FutureCrops
At Wimi Biotech, we don't just stop at a successful edit in the lab. Our mission is to see those genetic breakthroughs thrive where they belong—in the field.
#WimiBiotech #AgTech #FieldTrials #PlantScience #CropImprovement #FutureCrops
February 8, 2026 at 12:23 PM
Bridging the Gap from Lab Discovery to Field Reality 🌾🧪
At Wimi Biotech, we don't just stop at a successful edit in the lab. Our mission is to see those genetic breakthroughs thrive where they belong—in the field.
#WimiBiotech #AgTech #FieldTrials #PlantScience #CropImprovement #FutureCrops
At Wimi Biotech, we don't just stop at a successful edit in the lab. Our mission is to see those genetic breakthroughs thrive where they belong—in the field.
#WimiBiotech #AgTech #FieldTrials #PlantScience #CropImprovement #FutureCrops
Iron Management: How Plants Communicate from Roots to Shoots! 📢🧬
This review decrypts how plants use long-distance molecular signals between roots and shoots to maintain iron balance across organs.
Read the full paper: nph.onlinelibrary.wiley.com/doi/10.1111/...
#IronSignaling #CropBreeding
This review decrypts how plants use long-distance molecular signals between roots and shoots to maintain iron balance across organs.
Read the full paper: nph.onlinelibrary.wiley.com/doi/10.1111/...
#IronSignaling #CropBreeding
February 8, 2026 at 11:44 AM
Iron Management: How Plants Communicate from Roots to Shoots! 📢🧬
This review decrypts how plants use long-distance molecular signals between roots and shoots to maintain iron balance across organs.
Read the full paper: nph.onlinelibrary.wiley.com/doi/10.1111/...
#IronSignaling #CropBreeding
This review decrypts how plants use long-distance molecular signals between roots and shoots to maintain iron balance across organs.
Read the full paper: nph.onlinelibrary.wiley.com/doi/10.1111/...
#IronSignaling #CropBreeding
Breaking the Virus Cycle: A Faster Path to Virus-Free Plants! 🚀
A highly efficient combined protocol of Heat Treatment and Apical Meristem Culture to rapidly eliminate viruses from infected tissues.
Read the full paper: nph.onlinelibrary.wiley.com/.../10.1111/...
#CropImprovement #PlantPathology
A highly efficient combined protocol of Heat Treatment and Apical Meristem Culture to rapidly eliminate viruses from infected tissues.
Read the full paper: nph.onlinelibrary.wiley.com/.../10.1111/...
#CropImprovement #PlantPathology
February 8, 2026 at 11:30 AM
Breaking the Virus Cycle: A Faster Path to Virus-Free Plants! 🚀
A highly efficient combined protocol of Heat Treatment and Apical Meristem Culture to rapidly eliminate viruses from infected tissues.
Read the full paper: nph.onlinelibrary.wiley.com/.../10.1111/...
#CropImprovement #PlantPathology
A highly efficient combined protocol of Heat Treatment and Apical Meristem Culture to rapidly eliminate viruses from infected tissues.
Read the full paper: nph.onlinelibrary.wiley.com/.../10.1111/...
#CropImprovement #PlantPathology
Breaking the Efficiency Barrier: GPT-5 Meets Synthetic Biology! 🚀
Huge news from the intersection of AI and Biotech. GPT-5 is not just for chat—it’s now a powerful engine for scientific discovery.
OpenAI's Impact: openai.com/index/gpt-5-...
Ginkgo's Benchmark: www.prnewswire.com/news-release...
Huge news from the intersection of AI and Biotech. GPT-5 is not just for chat—it’s now a powerful engine for scientific discovery.
OpenAI's Impact: openai.com/index/gpt-5-...
Ginkgo's Benchmark: www.prnewswire.com/news-release...
February 6, 2026 at 6:15 AM
Breaking the Efficiency Barrier: GPT-5 Meets Synthetic Biology! 🚀
Huge news from the intersection of AI and Biotech. GPT-5 is not just for chat—it’s now a powerful engine for scientific discovery.
OpenAI's Impact: openai.com/index/gpt-5-...
Ginkgo's Benchmark: www.prnewswire.com/news-release...
Huge news from the intersection of AI and Biotech. GPT-5 is not just for chat—it’s now a powerful engine for scientific discovery.
OpenAI's Impact: openai.com/index/gpt-5-...
Ginkgo's Benchmark: www.prnewswire.com/news-release...
Rooting for Resilience: The Key to Climate-Smart Crops! 🚀
A must-read review in Frontiers in Plant Science on how Root System Architecture (RSA) is the next frontier for stabilizing global food security under increasing drought stress.
Read the full paper: doi.org/10.3389/fpls...
#RootBio #Drought
A must-read review in Frontiers in Plant Science on how Root System Architecture (RSA) is the next frontier for stabilizing global food security under increasing drought stress.
Read the full paper: doi.org/10.3389/fpls...
#RootBio #Drought
February 5, 2026 at 1:20 AM
Rooting for Resilience: The Key to Climate-Smart Crops! 🚀
A must-read review in Frontiers in Plant Science on how Root System Architecture (RSA) is the next frontier for stabilizing global food security under increasing drought stress.
Read the full paper: doi.org/10.3389/fpls...
#RootBio #Drought
A must-read review in Frontiers in Plant Science on how Root System Architecture (RSA) is the next frontier for stabilizing global food security under increasing drought stress.
Read the full paper: doi.org/10.3389/fpls...
#RootBio #Drought
Exciting read in JIPB on a new leap in plant genome engineering. The team has developed an optimized CRISPR-Cas9-mediated Prime Editing system to achieve precise integration of large DNA fragments in rice!
Read the full study: onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #GenomeEditing
Read the full study: onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #GenomeEditing
February 4, 2026 at 9:29 AM
Exciting read in JIPB on a new leap in plant genome engineering. The team has developed an optimized CRISPR-Cas9-mediated Prime Editing system to achieve precise integration of large DNA fragments in rice!
Read the full study: onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #GenomeEditing
Read the full study: onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #GenomeEditing