Will Shaw
@willshaw.bsky.social
Postdoc in Mo Khalil’s lab at Boston University • synthetic biology • genome engineering • plants • yeast
Reposted by Will Shaw
New paper from our lab on synthetic genome work in yeast is out - Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes. Exciting project led by Jane (Xinyu) Lu in our group, now online. t.co/0LuGwgAWlA
https://www.nature.com/articles/s41467-025-62356-y
t.co
August 11, 2025 at 12:36 PM
New paper from our lab on synthetic genome work in yeast is out - Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes. Exciting project led by Jane (Xinyu) Lu in our group, now online. t.co/0LuGwgAWlA
Reposted by Will Shaw
Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD in our group. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - specific adhesion, juxtacrine signalling and more. www.cell.com/cell/fulltex...
Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling
By designing synthetic toolkits for contact-based signaling (MARS) and cell-cell adhesion
(SATURN), we program yeast to form multicellular structures and perform complex tasks,
like building logic cir...
www.cell.com
July 11, 2025 at 3:01 PM
Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD in our group. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - specific adhesion, juxtacrine signalling and more. www.cell.com/cell/fulltex...
Reposted by Will Shaw
🚨 PhD project alert: Engineering a soil bacteria to sense and record soil health. 🦠 🪴 🥼 🧑💻 🌍
Fully funded PhD studenship in my group, open for international students. @earlhaminst.bsky.social
Please share widely! Deadline: 14th of May
www.earlham.ac.uk/studentship/...
Fully funded PhD studenship in my group, open for international students. @earlhaminst.bsky.social
Please share widely! Deadline: 14th of May
www.earlham.ac.uk/studentship/...
Sentinel bacteria: engineering a soil bacteria to sense and record soil health
www.earlham.ac.uk
April 15, 2025 at 9:25 AM
🚨 PhD project alert: Engineering a soil bacteria to sense and record soil health. 🦠 🪴 🥼 🧑💻 🌍
Fully funded PhD studenship in my group, open for international students. @earlhaminst.bsky.social
Please share widely! Deadline: 14th of May
www.earlham.ac.uk/studentship/...
Fully funded PhD studenship in my group, open for international students. @earlhaminst.bsky.social
Please share widely! Deadline: 14th of May
www.earlham.ac.uk/studentship/...
Thrilled to share that I will be moving back to the UK later in the year to start my next chapter as a Career Development Fellow at the Earlham Institute! 🌱🧬
💬 “Being in Norwich, at the heart of UK #plantsciences, will allow me to build strong collaborations and contribute to the development of resilient, sustainable #crops capable of meeting the challenges of a growing population and a changing climate.” - @willshaw.bsky.social
buff.ly/FQEQcIP #synbio
buff.ly/FQEQcIP #synbio
New Career Development Fellows enhance data-driven bioscience at the Earlham Institute
The Earlham Institute has appointed two new Career Development Fellows, supporting their journey towards establishing independent research groups.
buff.ly
March 18, 2025 at 11:42 PM
Thrilled to share that I will be moving back to the UK later in the year to start my next chapter as a Career Development Fellow at the Earlham Institute! 🌱🧬
Reposted by Will Shaw
Publications in the past week built substantially on our knowledge of the brain's waste disposal system—glymphatics—and the implications on sleep and brain aging.
Featuring exceptional work by Nedergaard Lab and @jonykipnis.bsky.social
erictopol.substack.com/p/our-sleep-... open-access
Featuring exceptional work by Nedergaard Lab and @jonykipnis.bsky.social
erictopol.substack.com/p/our-sleep-... open-access
Our Sleep, Brain Aging, and Waste Clearance
How sleep prevents "dirty" brains that age faster
erictopol.substack.com
January 12, 2025 at 4:20 PM
Publications in the past week built substantially on our knowledge of the brain's waste disposal system—glymphatics—and the implications on sleep and brain aging.
Featuring exceptional work by Nedergaard Lab and @jonykipnis.bsky.social
erictopol.substack.com/p/our-sleep-... open-access
Featuring exceptional work by Nedergaard Lab and @jonykipnis.bsky.social
erictopol.substack.com/p/our-sleep-... open-access
Reposted by Will Shaw
We’re looking for 3 postdocs to join our lab and work on engineering plant gene expression, metabolism and growth. If you have enthusiasm & skills in synthetic biology or metabolic engineering, apply by Jan 31.
www.jobs.cam.ac.uk/job/49767/
www.jobs.cam.ac.uk/job/49773/
www.jobs.cam.ac.uk/job/49769/
www.jobs.cam.ac.uk/job/49767/
www.jobs.cam.ac.uk/job/49773/
www.jobs.cam.ac.uk/job/49769/
January 2, 2025 at 4:15 PM
We’re looking for 3 postdocs to join our lab and work on engineering plant gene expression, metabolism and growth. If you have enthusiasm & skills in synthetic biology or metabolic engineering, apply by Jan 31.
www.jobs.cam.ac.uk/job/49767/
www.jobs.cam.ac.uk/job/49773/
www.jobs.cam.ac.uk/job/49769/
www.jobs.cam.ac.uk/job/49767/
www.jobs.cam.ac.uk/job/49773/
www.jobs.cam.ac.uk/job/49769/
Reposted by Will Shaw
Do you want an EMS-like drug that you can easily use in your lab or your garden shed to generate structural variation in your favorite plant? We show here that the topo2 inhibitor & common chemotherapy drug etoposide works really well to generate structural variation .
A simple method to efficiently generate structural variation in plants
Phenotypic variation is essential for the selection of new traits of interest. Structural variants, consisting of deletions, duplications, inversions, and translocations, have greater potential for ph...
www.biorxiv.org
December 21, 2024 at 10:23 PM
Do you want an EMS-like drug that you can easily use in your lab or your garden shed to generate structural variation in your favorite plant? We show here that the topo2 inhibitor & common chemotherapy drug etoposide works really well to generate structural variation .
Reposted by Will Shaw
Judge blocks rule that eased U.S. reviews of biotech crops
Some plant researchers fear the setback could last years and will stifle innovation. (From Science) #PlantScience
www.science.org/content/arti...
Judge blocks rule that eased U.S. reviews of biotech crops
Some plant researchers fear the setback could last years and will stifle innovation
www.science.org
December 11, 2024 at 8:28 AM
Judge blocks rule that eased U.S. reviews of biotech crops
Some plant researchers fear the setback could last years and will stifle innovation. (From Science) #PlantScience
www.science.org/content/arti...
Reposted by Will Shaw
Latest preprint from Jane (Xinyu Lu) in our group explores what happens when we build a synthetic genome cluster in yeast for Histidine biosynthesis and SCRaMbLE it to see whether selected-for gene rearrangements can guide better design.
Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes https://www.biorxiv.org/content/10.1101/2024.12.06.627136v1
December 8, 2024 at 1:55 PM
Latest preprint from Jane (Xinyu Lu) in our group explores what happens when we build a synthetic genome cluster in yeast for Histidine biosynthesis and SCRaMbLE it to see whether selected-for gene rearrangements can guide better design.