Karla Williams, PhD
@williamslab-ubc.bsky.social
Associate Prof @UBC| Canada Research Chair| #MetastasisResearch #CancerDiagnostics She/her. Opinions are my own.
https://www.williamslab.ca
ORCID: 0000-0003-2954-2869
https://www.williamslab.ca
ORCID: 0000-0003-2954-2869
More work coming out of the Williams lab. Could not wait to get it out, so here is the preprint on how cancer cells move into the lymphatic system and the importance of lymphatic metastases on global metastatic tumor burden:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Invadopodia-Mediated Remodeling of the Lymphatic Endothelium Drives Cancer Cell Lymphatic Dissemination and is Regulated by a CCR7-Vav2-Rac3 Signaling axis
Cancer cell invasion across a lymphatic endothelial barrier and subsequent colonization of regional lymph nodes often marks the first stage of metastatic dissemination. Lymphatic vessels facilitate th...
www.biorxiv.org
October 19, 2025 at 4:49 PM
More work coming out of the Williams lab. Could not wait to get it out, so here is the preprint on how cancer cells move into the lymphatic system and the importance of lymphatic metastases on global metastatic tumor burden:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
More work coming out of the Williams lab. Could not wait to get it out, so here is the preprint on how GABA drives cancer cell invasion in triple-negative breast cancer:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
GABA–GABAA Receptor Signaling Orchestrates Invasion and Metastasis in Triple Negative Breast Cancer
Cancer is a leading cause of death globally, with the majority of cancer-related deaths resulting from cancer metastasis −the process by which cancer cells disseminate to distant sites. To metastasize...
www.biorxiv.org
October 19, 2025 at 4:46 PM
More work coming out of the Williams lab. Could not wait to get it out, so here is the preprint on how GABA drives cancer cell invasion in triple-negative breast cancer:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Our latest work, “Circulating enolase 1 as a diagnostic biomarker for early-stage breast cancer”, is now published in npj Precision Oncology!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Circulating enolase 1 as a diagnostic biomarker for early-stage breast cancer - npj Precision Oncology
npj Precision Oncology - Circulating enolase 1 as a diagnostic biomarker for early-stage breast cancer
www.nature.com
October 19, 2025 at 4:40 PM
Our latest work, “Circulating enolase 1 as a diagnostic biomarker for early-stage breast cancer”, is now published in npj Precision Oncology!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Karla Williams, PhD
Happy birthday, David Attenborough! 99 ways he has inspired us, by Barack Obama, Billie Eilish, Morgan Freeman – and many more
Happy birthday, David Attenborough! 99 ways he has inspired us, by Barack Obama, Billie Eilish, Morgan Freeman – and many more
This week the presenter turns 99. To celebrate, we asked 99 nature lovers – including Margaret Atwood, Jane Fonda, Bono, Kate Winslet and Michael Palin – how he has helped us see the world with fresh eyes
www.theguardian.com
May 4, 2025 at 12:15 AM
Happy birthday, David Attenborough! 99 ways he has inspired us, by Barack Obama, Billie Eilish, Morgan Freeman – and many more
Reposted by Karla Williams, PhD
Dear Canadian researchers, faculty, RAs, PDFs and grad students, this letter is for the federal party leaders asking them to defend and expand Canadian research sovereignty with a historic investment in science, please sign and share
docs.google.com/document/d/1...
docs.google.com/document/d/1...
National Letter
Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...
docs.google.com
April 12, 2025 at 2:06 PM
Dear Canadian researchers, faculty, RAs, PDFs and grad students, this letter is for the federal party leaders asking them to defend and expand Canadian research sovereignty with a historic investment in science, please sign and share
docs.google.com/document/d/1...
docs.google.com/document/d/1...
Reposted by Karla Williams, PhD
Dr. Catharine Winstanley and Dr. Liisa Galea on why DEI is in everyone’s best interest:
"For decades, most biomedical research used only male subjects, particularly if model systems like cells or rodents were involved." 🧵⬇️
"For decades, most biomedical research used only male subjects, particularly if model systems like cells or rodents were involved." 🧵⬇️
If elected, Poilievre’s government will “put an end to the imposition of woke ideology in the federal civil service and federal funds for university research.”
The phrase is almost identical to wording used by the Trump administration.
Catharine Winstanley and @liisagalea.bsky.social write.
The phrase is almost identical to wording used by the Trump administration.
Catharine Winstanley and @liisagalea.bsky.social write.
By Attacking Science, Poilievre Takes a Page from Trump’s Playbook | The Tyee
Professors find this chilling and warn of the costs.
thetyee.ca
April 10, 2025 at 4:38 PM
Dr. Catharine Winstanley and Dr. Liisa Galea on why DEI is in everyone’s best interest:
"For decades, most biomedical research used only male subjects, particularly if model systems like cells or rodents were involved." 🧵⬇️
"For decades, most biomedical research used only male subjects, particularly if model systems like cells or rodents were involved." 🧵⬇️
Reposted by Karla Williams, PhD
Excited to share this collaborative work led by Guosong Hong’s group @stanfordneuro.bsky.social. A new method to render animals optically transparent for deep tissue imaging across the visible spectrum 🌈
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Color-neutral and reversible tissue transparency enables longitudinal deep-tissue imaging in live mice
Light scattering in biological tissue presents a significant challenge for deep in vivo imaging. Our previous work demonstrated the ability to achieve optical transparency in live mice using intensely...
www.biorxiv.org
February 28, 2025 at 6:39 AM
Excited to share this collaborative work led by Guosong Hong’s group @stanfordneuro.bsky.social. A new method to render animals optically transparent for deep tissue imaging across the visible spectrum 🌈
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Karla Williams, PhD
Reposted by Karla Williams, PhD
Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
November 25, 2024 at 1:47 PM
Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️