Adam Wheatley
@wheatleyak.viralvaxlab.com
Scientist in the @viralvaxlab (viralvaxlab.com) at @TheDohertyInst, father of daughters, cyclist. Views are mine, accept no imitations.
Reposted by Adam Wheatley
Happy to report that Mitchell's paper on CD4 T cells and AIM assays is now available online at Science Advances!
www.science.org/doi/10.1126/...
Thanks to all our collaborators in @viralvaxlab.bsky.social and @thedohertyinst.bsky.social, including @assocprofashhaque.bsky.social lab
www.science.org/doi/10.1126/...
Thanks to all our collaborators in @viralvaxlab.bsky.social and @thedohertyinst.bsky.social, including @assocprofashhaque.bsky.social lab
April 27, 2025 at 5:07 PM
Happy to report that Mitchell's paper on CD4 T cells and AIM assays is now available online at Science Advances!
www.science.org/doi/10.1126/...
Thanks to all our collaborators in @viralvaxlab.bsky.social and @thedohertyinst.bsky.social, including @assocprofashhaque.bsky.social lab
www.science.org/doi/10.1126/...
Thanks to all our collaborators in @viralvaxlab.bsky.social and @thedohertyinst.bsky.social, including @assocprofashhaque.bsky.social lab
Reposted by Adam Wheatley
Our latest study by PhD student #RomainGailleton shows that upon #influenza infection, #Bcell can respond rapidly by forming ectopic #GerminalCenter within the nasal tissue.
The work has just been published in @pnas.org (1/N)
www.pnas.org/doi/10.1073/...
The work has just been published in @pnas.org (1/N)
www.pnas.org/doi/10.1073/...
Ectopic germinal centers in the nasal turbinates contribute to B cell immunity to intranasal viral infection and vaccination | PNAS
The nasal mucosa is the first immunologically active site that respiratory viruses
encounter and establishing immunity at the initial point of path...
www.pnas.org
March 25, 2025 at 10:28 AM
Our latest study by PhD student #RomainGailleton shows that upon #influenza infection, #Bcell can respond rapidly by forming ectopic #GerminalCenter within the nasal tissue.
The work has just been published in @pnas.org (1/N)
www.pnas.org/doi/10.1073/...
The work has just been published in @pnas.org (1/N)
www.pnas.org/doi/10.1073/...
Reposted by Adam Wheatley
1/ Hot off the press in @jimmunol.bsky.social. We investigated how same side (ipsilateral) vs alternate side (contralateral) prime-boost vaccination impacts germinal center (GC) dynamics & antibody responses against SARS-CoV-2 spike in mice.💉🦠#immunology #vaccines @thedohertyinst.bsky.social
March 11, 2025 at 5:59 AM
1/ Hot off the press in @jimmunol.bsky.social. We investigated how same side (ipsilateral) vs alternate side (contralateral) prime-boost vaccination impacts germinal center (GC) dynamics & antibody responses against SARS-CoV-2 spike in mice.💉🦠#immunology #vaccines @thedohertyinst.bsky.social
Reposted by Adam Wheatley
New research from @thedohertyinst.bsky.social suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing #immunity quickly during a pandemic or disease #outbreak. #ReadTheJI #immunology
ow.ly/c28N50VeRGR
ow.ly/c28N50VeRGR
Modulation of germinal center and antibody dynamics via ipsilateral versus contralateral immunization against SARS-CoV-2
Abstract. Human clinical trials have reported immunological outcomes can differ between ipsilateral (same side) and contralateral (alternate sides) prime-b
ow.ly
March 10, 2025 at 3:09 PM
New research from @thedohertyinst.bsky.social suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing #immunity quickly during a pandemic or disease #outbreak. #ReadTheJI #immunology
ow.ly/c28N50VeRGR
ow.ly/c28N50VeRGR