Victor
banner
wediah.bsky.social
Victor
@wediah.bsky.social
I am interest in protein-protein interaction in cellular enviroments using physical tools
Reposted by Victor
Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs | Science Advances www.science.org/doi/10.1126/...
Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs
Receptors navigate cellular membranes by interacting with their curvature using an evolutionary conserved mechanism.
www.science.org
August 14, 2025 at 4:23 PM
Reposted by Victor
🍨Interested in reading more about the study? Here is the N&Vs article written by Jianguo Wu & Min Zhuang.
👉https://rdcu.be/eAObI
bit.ly/4mgzJvc
Pieces of the peroxisomal import puzzle - Nature Cell Biology
Peroxisomes are single membrane-bound organelles containing numerous enzymes to perform metabolic functions. However, our view of peroxisomal protein import has remained incomplete. Two recent studies...
bit.ly
August 14, 2025 at 8:30 PM
Reposted by Victor
🍹@martenslab.bsky.social @elias-adriaenssens.bsky.social & co show that, unlike soluble, transmembrane cargo receptors initiate autophagosome biogenesis by recruiting the FIP200/ULK1 or WIPI–ATG13 complex, revealing unexpected flexibility in the selective #autophagy machinery.
bit.ly/4lpGh9P
Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery - Nature Cell Biology
Adriaenssens et al. show that unlike soluble cargo receptors, transmembrane cargo receptors initiate autophagosome biogenesis by recruiting the FIP200/ULK1 or WIPI–ATG13 complex, revealing unexpected ...
bit.ly
August 14, 2025 at 8:07 PM
Reposted by Victor
Researchers have developed a #DeepLearning system called BioEmu that rapidly generates diverse protein conformations, enabling fast, accurate insights into protein flexibility and function.

Learn more this week in Science: https://scim.ag/3JdQVD4
August 14, 2025 at 6:05 PM
Reposted by Victor
Delighted to share one piece of my postdoc work in preprint: Through forward genetic screening for suberin deposition in root endodermis, we identified SUBER GENE 1 (SBG1) by GWAS as a novel regulator for suberization by interacting with Type One Protein Phosphatase. www.biorxiv.org/content/10.1...
May 11, 2025 at 10:04 AM
Reposted by Victor
Very proud to share our latest preprint: postdoc/LRSF fellow Yue Rui studies the mechanisms regulating attachment of the cell wall to the plasma membrane. The Cellulose Synthase Complex and REMORINs determine the extent of attachment and root osmotic stress tolerance. www.biorxiv.org/content/10.1...
August 3, 2025 at 3:53 AM
Reposted by Victor
I set out to review the evolution of eukaryotic intracellular traffic, but along the way a new hypothesis came into focus: maybe the earliest membrane carriers were tubules, not coated vesicles!

New preprint: ecoevorxiv.org/repository/v...

Here’s the idea. 🧵
August 4, 2025 at 8:34 PM