Felix Geist
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Felix Geist
@w2felix.bsky.social
170 followers 770 following 19 posts
Computational Biologist @Merck KGaA Darmstadt, DKFZ alumni. data-driven insights
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Reposted by Felix Geist
ldobsonhughes.bsky.social
A reminder the wealthy love to threaten to leave if left-wing politicians are elected. 10,000 media pieces alone before Labour were elected for example

Evidence shows almost 0% of them actually move. They have families, communities and home links. They just don’t move taxjustice.net/press/millio...
Millionaire exodus did not occur, study reveals - Tax Justice Network
The number of millionaires widely reported in the news to be leaving countries in "exodus" represented near-0% of all millionaires.
taxjustice.net
November 4, 2025 at 7:02 PM
Reposted by Felix Geist
signal.org
We are alarmed by reports that Germany is on the verge of a catastrophic about-face, reversing its longstanding and principled opposition to the EU’s Chat Control proposal which, if passed, could spell the end of the right to privacy in Europe. signal.org/blog/pdfs/ge...
signal.org
October 3, 2025 at 4:14 PM
Reposted by Felix Geist
const-ae.bsky.social
Our paper benchmarking foundation models for perturbation effect prediction is finally published 🎉🥳🎉

www.nature.com/articles/s41...

We show that none of the available* models outperform simple linear baselines. Since the original preprint, we added more methods, metrics, and prettier figures!

🧵
Beeswarm plot of the prediction error across different methods of double perturbations showing that all methods (scGPT, scFoundation, UCE, scBERT, Geneformer, GEARS, and CPA) perform worse than the additive baseline. Line plot of the true positive rate against the false discovery proportion showing that none of the methods is better at finding non additive interactions than simply predicting no change.
August 4, 2025 at 1:52 PM
Reposted by Felix Geist
taz.de
Ob Scheuer, Spahn oder Dobrindt – rechte Akteure hinterlassen gern einen Scherbenhaufen. Oft kommen sie dann auch noch ungeschoren davon.
Konservative Politik: Arbeit für die Aufräumer
Ob Scheuer, Spahn oder Dobrindt – rechte Akteure hinterlassen gern einen Scherbenhaufen. Oft kommen sie dann auch noch ungeschoren davon.
taz.de
June 18, 2025 at 6:08 AM
Reposted by Felix Geist
krstorevic.bsky.social
Wer glaubt, die „Ausländer raus“-Stimmung würde verschwinden, wenn weniger Geflüchtete kommen, sollte mal nach Ungarn schauen.

Im Kern geht es nicht um Herausforderungen durch Flucht und Migration, sondern darum, die Lust am Treten nach unten auszunutzen – für den eigenen Machterhalt.
June 2, 2025 at 8:15 PM
Reposted by Felix Geist
annikajoeres.bsky.social
Gerade mal wieder über die französisch-deutsche Grenze gefahren. Ausweiskontrolle, der Zug steht mehrere Minuten still.
Einige Fahrgäste grummeln. "Sind wir nicht Europa?".
Es ist ein trauriger und teurer Rückschritt.
May 26, 2025 at 10:30 AM
Reposted by Felix Geist
beyond-ideology.bsky.social
Sonderbericht des Bundesrechnungshofes: „Maßnahmen zur Stärkung der Einnahmebasis“. Dieser erklärt, an welchen Stellen der Staat noch strukturelle Defizite hat und zukünftig Geld einsparen könnte. Eines der Kernprobleme: Steuerbetrug.”

www.fr.de/wirtschaft/b...
„Nehmen den Staat auf allen Ebenen aus“: Report entlarvt Deutschlands wahre Sozialschmarotzer
Ein Bericht des Bundesrechnungshofs zeigt: Nicht Bürgergeld-Empfänger, sondern Steuerbetrüger kosten den Staat jährlich Milliarden.
www.fr.de
April 22, 2025 at 5:26 AM
Reposted by Felix Geist
biomedx.bsky.social
🌉 Today we launch #XBridge: a unique matchmaking program for U.S. researchers hit by #NIH #funding gaps.
We invite PIs to submit existing NIH proposals to connect with pharma partners via our platform. bio.mx/news/press-r...

Not a grant—an opportunity to keep science moving.
#StandUpForScience 🔬
April 8, 2025 at 7:57 AM
Reposted by Felix Geist
plantepigenetics.ch
As we can expect PubMed dysfunction more and more or to be swamped with fake journals I suggest you get acquainted to this nice alternative: europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
europepmc.org
March 2, 2025 at 7:54 AM
Reposted by Felix Geist
itaiyanai.bsky.social
"Innovations in Single Cell Omics" Berlin 5.12-13.
Organizers:
@stefaniegrosswendt.bsky.social
@simonhaas.bsky.social
@leifludwig.bsky.social
Ashley Sanders
@larsplus.bsky.social
@elimereu.bsky.social
@alejofraticelli.bsky.social
February 27, 2025 at 9:40 PM
Reposted by Felix Geist
teresabuecker.bsky.social
Friedrich Merz erzählt schon wieder auf Bühnen, Frauen würden die Grünen wählen, weil sie Habeck hot fänden.

Damit markiert er Frauen als »zu emotional für rationale Entscheidungen, für Politik«.

Genau damit wurde Frauen das Wahlrecht verwehrt.

Kein moderner Mensch kann diesen Mann unterstützen.
February 15, 2025 at 1:23 PM
Reposted by Felix Geist
cihancelik.bsky.social
Bei uns im Klinikum Darmstadt ist es wie in den meisten Gesundheitseinrichtungen in Deutschland: Unsere Vielfalt ist unsere Stärke.
February 14, 2025 at 6:49 PM
Reposted by Felix Geist
wkhuber.bsky.social
CSAMA 2025 Biological Data Science Summer School
in Brixen, South Tyrol, 7-11 July

We cover (sc)-RNA-seq and spatial omics data analysis, underlying (bio)statistical topics, multi-omics, ... All hands-on using R/Bioconductor tools.

csama2025.bioconductor.eu

Registration opens on 1 Feb
A picture of the surroundings of Brixen/Bressanone together with key data on the summer school.
January 27, 2025 at 4:06 PM
Reposted by Felix Geist
const-ae.bsky.social
After 4y in the making, I am super excited that my main PhD project is published 🎉🥳🎉🎉🥳

www.nature.com/articles/s41...

LEMUR is a tool to analyze multi-condition single-cell data and model differential expression as a continuous function of the cell-state space.

Some highlights⬇️
Overview of the LEMUR steps: (1) subspace alignment, (2) differential expression, (3) DE neighborhoods, (4) pseudobulking.
January 3, 2025 at 7:25 PM
Reposted by Felix Geist
dr-anis.bsky.social
I remember this plot and comment by @davidamuller.bsky.social from a while ago, which is probably still valid. I am waiting for Nature Reviews Comté
December 18, 2024 at 6:03 PM
Reposted by Felix Geist
dblipka.bsky.social
Looking for a #postdoc in #hematology in combination with #epigenomics, #metabolism and biochemistry? 👉Have a look at this opportunity in my lab. www.dkfz.de/en/postdoc-p... #HemeSky
www.dkfz.de
December 8, 2024 at 9:36 PM
Reposted by Felix Geist
brodnig.bsky.social
Wichtige Studie! Sie beobachtete, dass unseriöse Quellen, die Falschmeldungen verbreiten, mehr Empörung als vertrauenswürdige Nachrichtenquellen auslösen

Und Empörung begünstigt, dass Leute Falschmeldungen unhinterfragt teilen

Siehe: science.org/doi/10.1126/... (von @mjcrockett.bsky.social et al)
Je niedriger die Source Quality, desto mehr Wut-Reactions auf Facebook
December 5, 2024 at 11:39 AM
Reposted by Felix Geist
tmontsay.bsky.social
scRNA-seq has revolutionized biology, but it’s not without challenges. We uncovered significant quality issues in widely used reference cell atlases like the Human Cell Atlas and Tabula Sapiens. Up to 85% of cells in some datasets are low-quality or misidentified!
2/8
December 3, 2024 at 8:38 AM
Reposted by Felix Geist
obenaufa.bsky.social
1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...
November 27, 2024 at 5:58 PM
Reposted by Felix Geist
saezlab.bsky.social
We present NetworkCommons, a unified platform 🪐 for network biology, providing access to omics data, knowledge, and contextualization methods, all with a consistent API 👇🧵
Paper: doi.org/10.1101/2024...
Docs: networkcommons.readthedocs.io
November 26, 2024 at 9:44 AM
Reposted by Felix Geist
batllelab.bsky.social
We have an Open PostDoctoral Position in the Lab @IRBBarcelona.bsky.social 📢

Project on Tumour Immunology in collaboration with Ido Amit (Weizmann Institute of Science) and Holger Heyn (CNAG)

➡️ recruitment.irbbarcelona.org/jobs/5229393...
Postdoctoral Fellow (ref. PD/24/15) - IRB Barcelona
Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011. The ...
recruitment.irbbarcelona.org
November 26, 2024 at 1:38 PM