Vincent Nicholson
@vnchlsn.bsky.social
Research associate in the Boothby lab at the University of Wyoming. Posting mainly about science and occasionally about hockey and politics.
Professional Contact: vincentn@wustl.edu
Linktree: https://linktr.ee/vnchsln
Professional Contact: vincentn@wustl.edu
Linktree: https://linktr.ee/vnchsln
I'm super excited to share the most recent work from my time in the lab of Thomas Boothby at the University of Wyoming, in collaboration with @shaharsu.bsky.social!
Read the paper here: www.cell.com/action/showP...
Read the paper here: www.cell.com/action/showP...
www.cell.com
September 17, 2025 at 7:06 PM
I'm super excited to share the most recent work from my time in the lab of Thomas Boothby at the University of Wyoming, in collaboration with @shaharsu.bsky.social!
Read the paper here: www.cell.com/action/showP...
Read the paper here: www.cell.com/action/showP...
Reposted by Vincent Nicholson
More exciting news from the Center for Biomolecular Condensates at WashU McKelvey School of Engineering - Discoveries through technological innovations and conceptual leaps
engineering.washu.edu/news/2025/Un...
engineering.washu.edu/news/2025/Un...
Uncovering the electrochemistry of condensates
Researchers at Washington University in St. Louis are discovering the electrochemical properties of biomolecular condensates which could help in development of cancer or ALS treatments.
engineering.washu.edu
March 14, 2025 at 12:59 PM
More exciting news from the Center for Biomolecular Condensates at WashU McKelvey School of Engineering - Discoveries through technological innovations and conceptual leaps
engineering.washu.edu/news/2025/Un...
engineering.washu.edu/news/2025/Un...
Reposted by Vincent Nicholson
This message needs to be heard widely.
NIH funding delivers exponential economic returns — Harvard Gazette
Report finds all 50 states reap gains in patient health, job creation, research resources, business development.
news.harvard.edu
March 12, 2025 at 11:51 AM
This message needs to be heard widely.
Reposted by Vincent Nicholson
“NO SCIENCE, NO BEER” is potentially the most Fort Collins, Colorado protest chant of all time
March 7, 2025 at 8:14 PM
“NO SCIENCE, NO BEER” is potentially the most Fort Collins, Colorado protest chant of all time
Reposted by Vincent Nicholson
When universities cut their budgets, research and the local economies suffer 🧪: www.forbes.com/sites/michae...
As Feds Slash Funds, Research Universities Start To Trim Their Budgets
Amid worries about the Trump administration’s plans for research funding and higher education, major research universities have begun to tighten their budget belts.
www.forbes.com
February 19, 2025 at 6:14 AM
When universities cut their budgets, research and the local economies suffer 🧪: www.forbes.com/sites/michae...
Reposted by Vincent Nicholson
Excited to announce the newest member of the flock - STARLING (conSTruction of intrinsicAlly disoRdered proteins ensembles efficientLy vIa multi-dimeNsional Generative models).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
February 15, 2025 at 7:27 PM
Excited to announce the newest member of the flock - STARLING (conSTruction of intrinsicAlly disoRdered proteins ensembles efficientLy vIa multi-dimeNsional Generative models).
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Very happy to announce that my first-author paper, "LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation", is now published in Protein Science!!
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation
Organisms from all kingdoms of life depend on Late Embryogenesis Abundant (LEA) proteins to survive desiccation. LEA proteins are divided into broad families distinguished by the presence of family-s...
onlinelibrary.wiley.com
January 23, 2025 at 8:04 PM
Very happy to announce that my first-author paper, "LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation", is now published in Protein Science!!
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Vincent Nicholson
One of the highest compliments on scientific work is: “certainly someone must have done that earlier”
November 23, 2024 at 10:38 PM
One of the highest compliments on scientific work is: “certainly someone must have done that earlier”
Reposted by Vincent Nicholson
Our paper is out! To identify new protectant proteins we expressed tardigrade genes in bacteria and screened for those that could improve desiccation survival. It was a fun (and effective) screening approach. Check it out and see what we found! www.sciencedirect.com/science/arti...
A bacterial expression cloning screen reveals single-stranded DNA-binding proteins as potent desicco-protectants
Desiccation kills most cells. Some proteins have been identified to help certain cells survive desiccation, but many protein protectants are likely to…
www.sciencedirect.com
November 20, 2024 at 3:24 PM
Our paper is out! To identify new protectant proteins we expressed tardigrade genes in bacteria and screened for those that could improve desiccation survival. It was a fun (and effective) screening approach. Check it out and see what we found! www.sciencedirect.com/science/arti...
Reposted by Vincent Nicholson
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
November 17, 2024 at 4:20 PM
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
Reposted by Vincent Nicholson
New collaborative work in collaboration with the labs of Robert Best & Tanja Mittag driven by Ben Schuler.
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations
It has become increasingly evident that the conformational distributions of intrinsically disordered proteins or regions are strongly dependent on their amino acid compositions and sequence. To facili...
pubs.acs.org
November 15, 2024 at 4:56 PM
New collaborative work in collaboration with the labs of Robert Best & Tanja Mittag driven by Ben Schuler.
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations.
pubs.acs.org/doi/10.1021/...
Reposted by Vincent Nicholson
Breaking news: President-elect Donald Trump announced he had selected Robert F. Kennedy Jr. to run the Department of Health and Human Services, the agency responsible for administering millions of Americans’ health insurance and responding to infectious-disease outbreaks.
Live updates: Trump selects vaccine skeptic Robert F. Kennedy Jr. to lead HHS
Get the latest news on the transition to the new administration of President-elect Donald Trump and a new Congress.
www.washingtonpost.com
November 14, 2024 at 9:26 PM
Breaking news: President-elect Donald Trump announced he had selected Robert F. Kennedy Jr. to run the Department of Health and Human Services, the agency responsible for administering millions of Americans’ health insurance and responding to infectious-disease outbreaks.