Jean-Paul Armache
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valendraica.bsky.social
Jean-Paul Armache
@valendraica.bsky.social
Assistant Professor at Penn State University.
Looking at cool tiny complex things through electromagnetic lens.

Today, chromatin remodeling. Tomorrow? Who knows.

Opinions my own
We coupled in depth mutagenesis and biochemistry with high-resolution cryoEM, obtaining maps ranging from 2.37 to 2.9 Å.

This work was done by Ilana Nodelman (Bowman lab) and Heather Folkwein (Armache lab)

Thank you to everyone involved. It was a fun joint-venture!
May 30, 2025 at 3:12 PM
We did a thing... We purified native transcriptional complexes from Drosophila embryos, obtaining +/- stalk Pol II elongation complexes, native nucleosomes, as well as a nucleosome elongation complex. For more details please check out: doi.org/10.1101/2025...
February 5, 2025 at 1:02 AM