Marcelino and Al-Fatly et al. report literature-based lesion network mapping of dyskinetic cerebral palsy. Grey matter lesions are the most common MRI finding; the motor thalamus is a converging node of a wide functional network. Read at buff.ly/IyRv0E0.

MR guided focused ultrasound surgery is an effective and uprising treatment option for Essential tremor. But where is the optimal site to sonicate? Which spots to avoid due to side-effects?

@science.org @braincircuits.bsky.social @netstim.org

– a thread🧵!

www.science.org/doi/10.1126/...

New research reports " #Parkinsons patients who progress to poor outcomes, show white matter macrostructural loss already at baseline, evident both from imaging & fluid biomarkers"
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Incredibly happy and proud to share our newest work in
Science Transl Med showing that Aβ promotes neuronal hyperconnectivity, thereby driving tau spread across connected brain regions. Many thanks to first authors @sebroemer.bsky.social and Fabian Wagner!

science.org/doi/10.1126/...

Thread below

Interested in modeling DBS induced white matter activations?
Konstantin Butenko has a new preprint on all the options available within OSS-DBS / @lead-dbs.org including Electric Field Projections and probabilistic Pathway Activation Modeling:

www.medrxiv.org/content/10.1...

Do we need to stimulate different circuits to improve different dystonia symptoms with STN DBS? Work by Konstantin Butenko, @andreashorn.org @braincircuits.bsky.social out today in @PNAS says yes:
Engaging dystonia networks with subthalamic stimulation | PNAS www.pnas.org/doi/10.1073/...

Mapping neuropeptide signaling in the human brain | doi.org/10.1101/2024...

Neuropeptides are among the functionally diverse signaling molecules in the brain and body.

@cebric.bsky.social curates an atlas of neuropeptide receptors and relates it brain function 🧩 🧠 ⤵️