@tuchmnguyen.bsky.social
Reposted
The Church Evolution Lab (CEL@NYU) is hiring a postdoc! We have several new projects to study the genomic basis of biodiversity in model clades – especially Hawaiian Drosophila. apply.interfolio.com/179354
Come join our new group, you can study bugs and live in NYC! Feel free to share widely!
Come join our new group, you can study bugs and live in NYC! Feel free to share widely!
December 22, 2025 at 2:30 PM
The Church Evolution Lab (CEL@NYU) is hiring a postdoc! We have several new projects to study the genomic basis of biodiversity in model clades – especially Hawaiian Drosophila. apply.interfolio.com/179354
Come join our new group, you can study bugs and live in NYC! Feel free to share widely!
Come join our new group, you can study bugs and live in NYC! Feel free to share widely!
Reposted
Have you ever wondered: just how strong *is* the evidence for Muller's ratchet on mtDNA?
Well, wonder no more!
(Project led by Yu Mo, with @smishra677.bsky.social and @yadirapga.bsky.social)
"No molecular evidence for Muller's ratchet in mitochondrial genomes"
www.biorxiv.org/content/10.6...
Well, wonder no more!
(Project led by Yu Mo, with @smishra677.bsky.social and @yadirapga.bsky.social)
"No molecular evidence for Muller's ratchet in mitochondrial genomes"
www.biorxiv.org/content/10.6...
No molecular evidence for Muller's ratchet in mitochondrial genomes
Muller's ratchet predicts that non-recombining genomes can accumulate deleterious mutations, though molecular evidence for it is rare. Previous studies have tried to detect ratchet-like behavior in mi...
www.biorxiv.org
December 17, 2025 at 2:36 PM
Have you ever wondered: just how strong *is* the evidence for Muller's ratchet on mtDNA?
Well, wonder no more!
(Project led by Yu Mo, with @smishra677.bsky.social and @yadirapga.bsky.social)
"No molecular evidence for Muller's ratchet in mitochondrial genomes"
www.biorxiv.org/content/10.6...
Well, wonder no more!
(Project led by Yu Mo, with @smishra677.bsky.social and @yadirapga.bsky.social)
"No molecular evidence for Muller's ratchet in mitochondrial genomes"
www.biorxiv.org/content/10.6...
Reposted
Nguyen et al. used C. elegans as a model to study mitonuclear epistasis, leveraging genetic and phenotypic data to show that mitonuclear epistasis contributed significantly to phenotypic variance across all tested conditions.
🔗 doi.org/10.1093/molbev/msaf300
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf300
#evobio #molbio
Abundant Recurrent Mitochondrial Mutations and Widespread Mitonuclear Epistasis in Caenorhabditis elegans
Abstract. Coordinated genetic and physical interactions between mitochondrial and nuclear gene products regulate ATP production in the mitochondria. Linkin
doi.org
December 12, 2025 at 11:50 AM
Nguyen et al. used C. elegans as a model to study mitonuclear epistasis, leveraging genetic and phenotypic data to show that mitonuclear epistasis contributed significantly to phenotypic variance across all tested conditions.
🔗 doi.org/10.1093/molbev/msaf300
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf300
#evobio #molbio