Tyler Inskeep (they/them)
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trinskeep.bsky.social
Tyler Inskeep (they/them)
@trinskeep.bsky.social
PhD candidate in the Groen Lab @ UC Riverside. evolutionary systems biology, plant development, root-knot nematodes. they/them
Reposted by Tyler Inskeep (they/them)
🔥my latest paper from @odedrechavi.bsky.social lab🔥
we found small RNAs act across tissues to regulate fertlity in C. elegans 🪱. Surprisingly, we also found that O2-sensing neurons inhibit germline maintenance. Follow along our journey👇https://www.biorxiv.org/content/10.1101/2025.08.07.669182v1
August 11, 2025 at 8:26 AM
Reposted by Tyler Inskeep (they/them)
🚨New paper published in @nature.com! Using pan-genetics across the Solanum genus🍅🥔🍆we reveal why gene duplications🧬are major contingencies in crop engineering. My postdoc work in the Lippman lab @CSHL, collab. with @katiejenike.bsky.social @mikeschatz.bsky.social chatz.bsky.social and many others!
Solanum pan-genetics reveals paralogues as contingencies in crop engineering - Nature
Gene duplication and subsequent paralogue diversification are major obstacles to genotype-to-phenotype predictability.
nature.com
March 5, 2025 at 4:43 PM
🚨 excited to share that my first, first author manuscript is now accessible on biorxiv!

in it, my mentor @simoncgroen.bsky.social and I explore how gene expression evolves in real time in C. elegans, leveraging an incredible dataset from Erik Andersen’s group!

www.biorxiv.org/content/10.1...
Network properties constrain natural selection on gene expression in Caenorhabditis elegans
Gene regulatory networks (GRNs) integrate genetic and environmental signals to coordinate complex phenotypes and evolve through a balance of selection and drift. Using publicly available datasets from...
www.biorxiv.org
February 26, 2025 at 1:17 AM