Tolaasin
tolaasin.bsky.social
Tolaasin
@tolaasin.bsky.social
Analytical chemist, enthusiastic woodworker, oldest netrunner in the world. He/him.
Just finished this deck box for a friend
December 11, 2024 at 1:00 PM
November 27, 2024 at 5:49 PM
Interesting molecules I've worked on (3): XFIN31 and TF3A5 are zinc finger units involved in regulating DNA transcription, and novel in that despite only having between 25 and 30 residues they adopt a stable structure containing two secondary structure units, an alpha-helix and a beta-sheet.🧪
November 25, 2024 at 11:00 AM
interesting molecules I have worked on, no 2.
Phospholamban is a 52 residue protein which regulates heart muscle contractility, in it's native state, it acts as a brake, when phosphorylated, it potentiates cardiac contractility. 🧪
November 22, 2024 at 10:26 AM
So, tolaasin, I hear you ask? What's the deal with the name? Mushrooms go brown because a bacterium, P. tolaasii, colonises the surface and secretes a lytic toxin, tolaasin, which is unique in having a left-handed alpha-helix made of D-amino acids. My PhD covered its structure determination.
🧪
November 18, 2024 at 10:37 AM
An exhausting but rewarding day being the eyes for an amazing player and friend at the UK Netrunner National championships in Sheffield.
November 16, 2024 at 10:43 PM
When two interests intersect - woodworking, and analytical chemistry. I made this box from purpleheart wood, the intense purple colour is a consequence of the presence of Peltogynoid Quinone Methides. 🧪
www.mdpi.com/1420-3049/21...
November 15, 2024 at 7:55 PM
I’ve made a token box but I flocked the inside.
November 14, 2024 at 6:52 PM
Just finished this deck box as a gift for a friend - purple heart and walnut. #woodworking
November 14, 2024 at 6:42 PM