Onur Özer
@tmrca.bsky.social
Human Genetics, Evolution, Immunology, HLA
Timeo Hominem Unius Libri
Timeo Hominem Unius Libri
Pinned
Onur Özer
@tmrca.bsky.social
· Jun 17
HLA PCA Viewer (1000 Genomes + Your Genotype)
onur-ozer.shinyapps.io
Have you recently registered as a blood marrow donor and got your HLA genotyped?
Why don’t you try this little app I built?
HLA PCA Viewer is a Shiny app that plots your HLA genotype onto a PCA space derived from the 1000 Genomes Project.
onur-ozer.shinyapps.io/hla-pca/
github.com/onur-ozer/HL...
Why don’t you try this little app I built?
HLA PCA Viewer is a Shiny app that plots your HLA genotype onto a PCA space derived from the 1000 Genomes Project.
onur-ozer.shinyapps.io/hla-pca/
github.com/onur-ozer/HL...
Reposted by Onur Özer
The most important article and critical warning you’ll read, until it’s too late
www.authoritarian-stack.info
www.authoritarian-stack.info
The Authoritarian Stack
How Tech Billionaires Are Building a Post-Democratic America — And Why Europe Is Next
www.authoritarian-stack.info
November 8, 2025 at 6:33 PM
The most important article and critical warning you’ll read, until it’s too late
www.authoritarian-stack.info
www.authoritarian-stack.info
Reposted by Onur Özer
New manuscript out in NAR! tinyurl.com/4rrbuesn
🧬 VDJbase and OGRDB now support 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. From population analysis to precision annotation. @guryaari.bsky.social @cdubsig.bsky.social @williamlees.bsky.social
🧬 VDJbase and OGRDB now support 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. From population analysis to precision annotation. @guryaari.bsky.social @cdubsig.bsky.social @williamlees.bsky.social
The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbase
Abstract. Accurate characterization of adaptive immune receptor repertoires through high-throughput sequencing is critical for understanding immune respons
academic.oup.com
November 7, 2025 at 2:19 PM
New manuscript out in NAR! tinyurl.com/4rrbuesn
🧬 VDJbase and OGRDB now support 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. From population analysis to precision annotation. @guryaari.bsky.social @cdubsig.bsky.social @williamlees.bsky.social
🧬 VDJbase and OGRDB now support 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. From population analysis to precision annotation. @guryaari.bsky.social @cdubsig.bsky.social @williamlees.bsky.social
A new paper about #longevity and #HLA: Men with HLA-DRB1*15:01 might be among the unlucky ones...
“HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men”
It was great to work with Nicolas on that paper!
genomemedicine.biomedcentral.com/articles/10....
“HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men”
It was great to work with Nicolas on that paper!
genomemedicine.biomedcentral.com/articles/10....
HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men - Genome Medicine
Background Prior research on the genetics of human longevity has identified only a few robust associations. While these studies highlight the importance of metabolic processes for longevity, the contr...
genomemedicine.biomedcentral.com
October 27, 2025 at 3:18 PM
A new paper about #longevity and #HLA: Men with HLA-DRB1*15:01 might be among the unlucky ones...
“HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men”
It was great to work with Nicolas on that paper!
genomemedicine.biomedcentral.com/articles/10....
“HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men”
It was great to work with Nicolas on that paper!
genomemedicine.biomedcentral.com/articles/10....
Reposted by Onur Özer
Join Our Citizen Science Project!
We are mapping the house mouse hybrid zone in Schleswig-Holstein, DE, and you can help. Visit our House Mouse Hybrid Zone Project website to learn more jwinternitz.github.io/mouse-hybrid.... Funded by @dfg.de at @uni-hamburg.de
#DFG #musmusculus #wildmice
We are mapping the house mouse hybrid zone in Schleswig-Holstein, DE, and you can help. Visit our House Mouse Hybrid Zone Project website to learn more jwinternitz.github.io/mouse-hybrid.... Funded by @dfg.de at @uni-hamburg.de
#DFG #musmusculus #wildmice
October 13, 2025 at 11:53 AM
Join Our Citizen Science Project!
We are mapping the house mouse hybrid zone in Schleswig-Holstein, DE, and you can help. Visit our House Mouse Hybrid Zone Project website to learn more jwinternitz.github.io/mouse-hybrid.... Funded by @dfg.de at @uni-hamburg.de
#DFG #musmusculus #wildmice
We are mapping the house mouse hybrid zone in Schleswig-Holstein, DE, and you can help. Visit our House Mouse Hybrid Zone Project website to learn more jwinternitz.github.io/mouse-hybrid.... Funded by @dfg.de at @uni-hamburg.de
#DFG #musmusculus #wildmice
Reposted by Onur Özer
Brilliant paper by Visscher et al.
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
Direct effect of genetic ancestry on complex traits in a Mexican population
Human populations differ in disease prevalences and in average values of phenotypes, but the extent to which differences are caused by genetic or environmental factors is unknown for most complex trai...
www.medrxiv.org
September 11, 2025 at 5:57 AM
Brilliant paper by Visscher et al.
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
I remember back when I was learning Python, a computer engineer mentioned objects and I asked "What is an object?" The answer was: "What do you mean? Everything is an object in Python!" and he continued without expanding.
I wish more explanations like this were available back then...
I wish more explanations like this were available back then...
1/
What the heck is an "object" (like a Seurat object) in programming?
If you're in bioinformatics, this term shows up a lot.
Let’s break it down with examples that actually make sense 🧵
What the heck is an "object" (like a Seurat object) in programming?
If you're in bioinformatics, this term shows up a lot.
Let’s break it down with examples that actually make sense 🧵
June 29, 2025 at 1:25 PM
I remember back when I was learning Python, a computer engineer mentioned objects and I asked "What is an object?" The answer was: "What do you mean? Everything is an object in Python!" and he continued without expanding.
I wish more explanations like this were available back then...
I wish more explanations like this were available back then...
Reposted by Onur Özer
Happy to share our new study from my PhD on the spread of farming across Anatolia and into the Aegean and then into Europe. @compevohumang.bsky.social
www.science.org/doi/10.1126/...
👇🏽
www.science.org/doi/10.1126/...
👇🏽
Out-of-Anatolia: Cultural and genetic interactions during the Neolithic expansion in the Aegean
West Anatolia has been a crucial yet elusive element in the Neolithic expansion from the Fertile Crescent to Europe. In this work, we describe the changing genetic and cultural landscapes of early Hol...
www.science.org
June 26, 2025 at 6:07 PM
Happy to share our new study from my PhD on the spread of farming across Anatolia and into the Aegean and then into Europe. @compevohumang.bsky.social
www.science.org/doi/10.1126/...
👇🏽
www.science.org/doi/10.1126/...
👇🏽
Reposted by Onur Özer
A Matriarchal Society Existed in Çatalhöyük During the Neolithic More Than 10,000 Years Ago, Researchers Find www.labrujulaverde.com/en/2025/06/a...
A Matriarchal Society Existed in Çatalhöyük During the Neolithic More Than 10,000 Years Ago, Researchers Find
On the Anatolian plains, more than ten thousand years ago, one of humanity’s first major farming communities flourished, burying its dead beneath the floors of its homes. Now, two recently published s...
www.labrujulaverde.com
June 27, 2025 at 7:29 AM
A Matriarchal Society Existed in Çatalhöyük During the Neolithic More Than 10,000 Years Ago, Researchers Find www.labrujulaverde.com/en/2025/06/a...
Have you recently registered as a blood marrow donor and got your HLA genotyped?
Why don’t you try this little app I built?
HLA PCA Viewer is a Shiny app that plots your HLA genotype onto a PCA space derived from the 1000 Genomes Project.
onur-ozer.shinyapps.io/hla-pca/
github.com/onur-ozer/HL...
Why don’t you try this little app I built?
HLA PCA Viewer is a Shiny app that plots your HLA genotype onto a PCA space derived from the 1000 Genomes Project.
onur-ozer.shinyapps.io/hla-pca/
github.com/onur-ozer/HL...
HLA PCA Viewer (1000 Genomes + Your Genotype)
onur-ozer.shinyapps.io
June 17, 2025 at 2:18 PM
Have you recently registered as a blood marrow donor and got your HLA genotyped?
Why don’t you try this little app I built?
HLA PCA Viewer is a Shiny app that plots your HLA genotype onto a PCA space derived from the 1000 Genomes Project.
onur-ozer.shinyapps.io/hla-pca/
github.com/onur-ozer/HL...
Why don’t you try this little app I built?
HLA PCA Viewer is a Shiny app that plots your HLA genotype onto a PCA space derived from the 1000 Genomes Project.
onur-ozer.shinyapps.io/hla-pca/
github.com/onur-ozer/HL...
I am honored and humbled to receive the Jon van Rood Award for Best Abstract at EFI 2025! My first EFI was amazing and I am looking forward to many more ahead! #EFI2025 #immunogenetics
June 9, 2025 at 1:35 PM
I am honored and humbled to receive the Jon van Rood Award for Best Abstract at EFI 2025! My first EFI was amazing and I am looking forward to many more ahead! #EFI2025 #immunogenetics
#EFI2025 is about to kick off in beautiful Prague! 🇨🇿
I’ll be presenting in the Best Abstracts session on Saturday, sharing our work on ancient HLA diversity in Europe. Super excited for a week of science, new connections, and fresh ideas!
#HLA #AncientDNA #Immunogenetics #MHC
I’ll be presenting in the Best Abstracts session on Saturday, sharing our work on ancient HLA diversity in Europe. Super excited for a week of science, new connections, and fresh ideas!
#HLA #AncientDNA #Immunogenetics #MHC
May 14, 2025 at 9:23 AM
#EFI2025 is about to kick off in beautiful Prague! 🇨🇿
I’ll be presenting in the Best Abstracts session on Saturday, sharing our work on ancient HLA diversity in Europe. Super excited for a week of science, new connections, and fresh ideas!
#HLA #AncientDNA #Immunogenetics #MHC
I’ll be presenting in the Best Abstracts session on Saturday, sharing our work on ancient HLA diversity in Europe. Super excited for a week of science, new connections, and fresh ideas!
#HLA #AncientDNA #Immunogenetics #MHC
I have always been proud of my university ODTÜ in Turkey, not only for its academic success but also for the political stance of students. Right now, this is the treatment faced by students who stand up for democracy.
(photo credit unknown for now)
(photo credit unknown for now)
March 27, 2025 at 4:50 PM
I have always been proud of my university ODTÜ in Turkey, not only for its academic success but also for the political stance of students. Right now, this is the treatment faced by students who stand up for democracy.
(photo credit unknown for now)
(photo credit unknown for now)
Hello Blue world!
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...
Admixture as a source for HLA variation in Neolithic European farming communities - Genome Biology
Background The northern European Neolithic is characterized by two major demographic events: immigration of early farmers from Anatolia at 7500 years before present, and their admixture with local wes...
doi.org
March 24, 2025 at 2:13 PM
Hello Blue world!
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...