Onur Özer
tmrca.bsky.social
Onur Özer
@tmrca.bsky.social
Human Genetics, Evolution, Immunology, HLA
Timeo Hominem Unius Libri
Ahhh... Thanks for the warning. Unfortunately, I cannot edit the post. I will make a new post with the correct link. In the meantime, here it is:

genomemedicine.biomedcentral.com/articles/10....
HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men - Genome Medicine
Background Prior research on the genetics of human longevity has identified only a few robust associations. While these studies highlight the importance of metabolic processes for longevity, the contr...
genomemedicine.biomedcentral.com
October 27, 2025 at 3:15 PM
Anyway, I will cut it short. The people of Turkey are suffering under a crushing economic decline, political oppression, censorship, a degrading quality of education and a collapsed electoral system. We are digging under the rubble with the hope of seeing the light.
March 27, 2025 at 4:50 PM
Resistance against the current regime is nothing new. I began my bachelor's in 2010, and my entire university life was marked by pepper spray, batons, water cannons, and plastic bullets. Yet, at the time, the regime was being praised in Europe for its supposed "democratic" values.
March 27, 2025 at 4:50 PM
Sadly, all of this was not only supported by the usual suspects of the far-right, but also by liberals, greens, social democrats, etc. Anyone can be accommodated, even praised, as long as they are useful. This has been the case for the regime in Turkey for a long time.
March 27, 2025 at 4:50 PM
Syria was handed over to an ISIS commander with a million-dollar reward on his head just a few months ago. Taliban leaders are quietly being removed from terrorist lists. The rabid far-right government of Israel gets unconditional support for its massacre of Palestinians.
March 27, 2025 at 4:50 PM
Authoritarianism is on the rise across the globe, paving the way for extremist governments. In our interconnected world, ignoring the suffering of ordinary people is no longer an option. Unfortunately, the Western world has recently failed many tests in this regard.
March 27, 2025 at 4:50 PM
Anybody who dares to speak up against the party-state feels "the Iron Heel". Hundreds of citizens -students, journalists, politicians- are under arrest, websites are blocked, TV channels are getting broadcast bans. All to ensure the continuation of a corrupt regime.
March 27, 2025 at 4:50 PM
This is not an isolated case, of course. If you have been following the news, you are likely aware of the ongoing political crackdown in Turkey. Here is a summary of the situation (from 5 days ago). Since then, the crackdown only escalated.

kulturkampftr.substack.com/p/turkey-res...
Turkey Resists
By arresting İmamoğlu, Erdoğan banks on public apathy. He's getting the opposite.
kulturkampftr.substack.com
March 27, 2025 at 4:50 PM
Leadership is busy beating their own best & brightest at universities right now. Plus, the stance that Turkey's ruling regime has adopted regarding Palestine is only performative, aimed at consolidating their voter base. They would shout a few words for that lady if they see benefit, nothing more.
March 26, 2025 at 8:39 PM
I will present some results of this study together with our other projects on ancient #HLA diversity in Europe at the 38th European Immunogenetics & Histocompatibility Conference #EFI2025

#MHC #immunogenomics #ancientDNA
March 24, 2025 at 2:30 PM
More importantly, we don't know if that haplotype was already common in WHG or not. Having some frequency data would allow us to estimate expected frequencies after the admixture and test whether the observed frequency can be explained solely by admixture or not.
March 24, 2025 at 2:13 PM
What could be the reason for this excess WHG ancestry across the MHC region? Our pathogen screening did not provide any obvious target. There are some associations between DRB1*08:01-DQB1*04:02 alleles and some pathogens, notably the hepatitis-B virus. But was it enough to drive such a signal?
March 24, 2025 at 2:13 PM
Combining targeted HLA genotyping with the genomewide data, we found that LF individuals carrying DRB1*08:01-DQB1*04:02 haplotype had an excess of WHG ancestry across the MHC region, suggesting that this haplotype introgressed from the hunter-gatherers.
March 24, 2025 at 2:13 PM