Cambridge Institute for Medical Research
@thecimr.bsky.social
An interdisciplinary institute within University of Cambridge School of Clinical Medicine
Determining the molecular mechanisms of human disease, focusing on genetic/ pathogen-induced disruptions to fundamental cellular pathways
https://www.cimr.cam.ac.uk/
Determining the molecular mechanisms of human disease, focusing on genetic/ pathogen-induced disruptions to fundamental cellular pathways
https://www.cimr.cam.ac.uk/
Pinned
Hello! Although we are still in the other place, this will become our main social media feed. We're part of the University of Cambridge Clinical School
Cell biology, molecular mechanisms of human disease
Cell biology, molecular mechanisms of human disease
Reposted by Cambridge Institute for Medical Research
The Cambridge Biomedical Campus Open Mic returns! With a fully stocked bar and food on sale, whether you’re performing or just soaking up the atmosphere, everyone is welcome – you don’t need to work at the Biomedical Campus to join in!
Find out more: cambridge-biomedical.com/event/open-m...
Find out more: cambridge-biomedical.com/event/open-m...
November 6, 2025 at 2:44 PM
The Cambridge Biomedical Campus Open Mic returns! With a fully stocked bar and food on sale, whether you’re performing or just soaking up the atmosphere, everyone is welcome – you don’t need to work at the Biomedical Campus to join in!
Find out more: cambridge-biomedical.com/event/open-m...
Find out more: cambridge-biomedical.com/event/open-m...
Our mission is to determine the molecular mechanisms of disease in order to advance human health.
Want to join our vibrant and diverse research institute as a funded PhD or taught MPhil student? Apply by the 2nd December 2025.
More information here: www.cimr.cam.ac.uk/postgraduate...
Want to join our vibrant and diverse research institute as a funded PhD or taught MPhil student? Apply by the 2nd December 2025.
More information here: www.cimr.cam.ac.uk/postgraduate...
November 6, 2025 at 10:40 AM
Our mission is to determine the molecular mechanisms of disease in order to advance human health.
Want to join our vibrant and diverse research institute as a funded PhD or taught MPhil student? Apply by the 2nd December 2025.
More information here: www.cimr.cam.ac.uk/postgraduate...
Want to join our vibrant and diverse research institute as a funded PhD or taught MPhil student? Apply by the 2nd December 2025.
More information here: www.cimr.cam.ac.uk/postgraduate...
Great win for @darwincollegecam.bsky.social in last night's University Challenge - featuring CIMR PhD student Lewis Strachan. Well done team!
November 4, 2025 at 2:30 PM
Great win for @darwincollegecam.bsky.social in last night's University Challenge - featuring CIMR PhD student Lewis Strachan. Well done team!
Fantastic news! Well done Lily
I'm very honoured to have been chosen for the Alpha-1 Antitrypsin Laurell's Training Award (ALTA), an early-career research fellowship
I would like to thank my supervisors @profmarciniak.bsky.social @joechambers.bsky.social, and my wonderful institute @thecimr.bsky.social for making this possible!
I would like to thank my supervisors @profmarciniak.bsky.social @joechambers.bsky.social, and my wonderful institute @thecimr.bsky.social for making this possible!
October 27, 2025 at 9:55 AM
Fantastic news! Well done Lily
Reposted by Cambridge Institute for Medical Research
Spread the word! Outstanding UK students can experience life at Catz
@isaacphysics.org STEM SMART: apply by 31 Oct undergraduate.study....
@thecimr.bsky.social Inspiring Scientists: apply by 21 Nov cimr.cam.ac.uk/inspi...
@cam.ac.uk Bangla Soc Access Day: apply by 15 Dec forms.gle/KReLakbpAS...
@isaacphysics.org STEM SMART: apply by 31 Oct undergraduate.study....
@thecimr.bsky.social Inspiring Scientists: apply by 21 Nov cimr.cam.ac.uk/inspi...
@cam.ac.uk Bangla Soc Access Day: apply by 15 Dec forms.gle/KReLakbpAS...
October 27, 2025 at 9:15 AM
Spread the word! Outstanding UK students can experience life at Catz
@isaacphysics.org STEM SMART: apply by 31 Oct undergraduate.study....
@thecimr.bsky.social Inspiring Scientists: apply by 21 Nov cimr.cam.ac.uk/inspi...
@cam.ac.uk Bangla Soc Access Day: apply by 15 Dec forms.gle/KReLakbpAS...
@isaacphysics.org STEM SMART: apply by 31 Oct undergraduate.study....
@thecimr.bsky.social Inspiring Scientists: apply by 21 Nov cimr.cam.ac.uk/inspi...
@cam.ac.uk Bangla Soc Access Day: apply by 15 Dec forms.gle/KReLakbpAS...
Reposted by Cambridge Institute for Medical Research
The beginning of a new era. Behold the Dickens lab @thecimr.bsky.social - small but perfectly formed. Excited for what is to come! Thanks @profmarciniak.bsky.social for letting me squat until now…
October 14, 2025 at 4:46 PM
The beginning of a new era. Behold the Dickens lab @thecimr.bsky.social - small but perfectly formed. Excited for what is to come! Thanks @profmarciniak.bsky.social for letting me squat until now…
Reposted by Cambridge Institute for Medical Research
As always, the Big Biology Day at Hills Rd Sixth Form was an absolute blast! A great morning with @alzheimersresearchuk.org and a great afternoon with @thecimr.bsky.social
October 11, 2025 at 3:39 PM
As always, the Big Biology Day at Hills Rd Sixth Form was an absolute blast! A great morning with @alzheimersresearchuk.org and a great afternoon with @thecimr.bsky.social
Reposted by Cambridge Institute for Medical Research
The #RAREsummit25 agenda is live!
Packed with diverse voices, patient-driven insights & bold innovation.
www.camraredisease.org/raresummit25...
Grab your ticket to join us on 6 Nov to be part of the conversation & on't forget to book your dinner spot!
What are you most looking forward to?
Packed with diverse voices, patient-driven insights & bold innovation.
www.camraredisease.org/raresummit25...
Grab your ticket to join us on 6 Nov to be part of the conversation & on't forget to book your dinner spot!
What are you most looking forward to?
October 9, 2025 at 10:27 AM
The #RAREsummit25 agenda is live!
Packed with diverse voices, patient-driven insights & bold innovation.
www.camraredisease.org/raresummit25...
Grab your ticket to join us on 6 Nov to be part of the conversation & on't forget to book your dinner spot!
What are you most looking forward to?
Packed with diverse voices, patient-driven insights & bold innovation.
www.camraredisease.org/raresummit25...
Grab your ticket to join us on 6 Nov to be part of the conversation & on't forget to book your dinner spot!
What are you most looking forward to?
We've just welcomed this year's cohort of MPhil students studying the Molecular Mechanism of Human Disease so it's time to start preparing for next year! Applications are now open - details and link to apply here: www.cimr.cam.ac.uk/masters-mole...
October 9, 2025 at 10:06 AM
We've just welcomed this year's cohort of MPhil students studying the Molecular Mechanism of Human Disease so it's time to start preparing for next year! Applications are now open - details and link to apply here: www.cimr.cam.ac.uk/masters-mole...
Reposted by Cambridge Institute for Medical Research
Only two more days to go!! This Saturday from 10am to 4pm at Hills Road Sixth Form @thecimr.bsky.social will be joining Big Biology Day. Come along and bring your #family to join in lots of #fun #science activities.
We're looking forward to the Big Biology Day at Hills Road Sixth Form on Saturday 11th October - who's coming?
October 9, 2025 at 7:40 AM
Only two more days to go!! This Saturday from 10am to 4pm at Hills Road Sixth Form @thecimr.bsky.social will be joining Big Biology Day. Come along and bring your #family to join in lots of #fun #science activities.
Applications now open for our work experience programme for year 12 students, run with @mrc-mbu.bsky.social & @stcatharines.bsky.social We give students a valuable insight into life as a research scientist and student in Cambridge. Details & application link here: www.cimr.cam.ac.uk/inspiring-sc...
October 7, 2025 at 12:43 PM
Applications now open for our work experience programme for year 12 students, run with @mrc-mbu.bsky.social & @stcatharines.bsky.social We give students a valuable insight into life as a research scientist and student in Cambridge. Details & application link here: www.cimr.cam.ac.uk/inspiring-sc...
Great to welcome our second cohort of students to our Masters in Molecular Mechanism of Human Disease today. Have a good year everyone!
October 7, 2025 at 12:28 PM
Great to welcome our second cohort of students to our Masters in Molecular Mechanism of Human Disease today. Have a good year everyone!
We're looking forward to the Big Biology Day at Hills Road Sixth Form on Saturday 11th October - who's coming?
September 29, 2025 at 10:03 AM
We're looking forward to the Big Biology Day at Hills Road Sixth Form on Saturday 11th October - who's coming?
Reposted by Cambridge Institute for Medical Research
*job alert**
Wanted - 2 enthusiastic postdocs to join me @thecimr.bsky.social and Emma Rawlins @labrawlins.bsky.social to build complex models and use -omic approaches to understand mechanisms in human lung disease in collaboration with GSK. Contact us for more info!
www.jobs.cam.ac.uk/job/52936/
Wanted - 2 enthusiastic postdocs to join me @thecimr.bsky.social and Emma Rawlins @labrawlins.bsky.social to build complex models and use -omic approaches to understand mechanisms in human lung disease in collaboration with GSK. Contact us for more info!
www.jobs.cam.ac.uk/job/52936/
Research Associate: Human Lung Disease Mechanisms (Fixed Term) - Job Opportunities - University of Cambridge
Research Associate: Human Lung Disease Mechanisms (Fixed Term) in the Gurdon Institute at the University of Cambridge.
www.jobs.cam.ac.uk
September 25, 2025 at 11:21 AM
*job alert**
Wanted - 2 enthusiastic postdocs to join me @thecimr.bsky.social and Emma Rawlins @labrawlins.bsky.social to build complex models and use -omic approaches to understand mechanisms in human lung disease in collaboration with GSK. Contact us for more info!
www.jobs.cam.ac.uk/job/52936/
Wanted - 2 enthusiastic postdocs to join me @thecimr.bsky.social and Emma Rawlins @labrawlins.bsky.social to build complex models and use -omic approaches to understand mechanisms in human lung disease in collaboration with GSK. Contact us for more info!
www.jobs.cam.ac.uk/job/52936/
Great new paper highlighting @jenniferepalmer.bsky.social 's PhD work: www.cimr.cam.ac.uk/research-adv...
September 16, 2025 at 1:44 PM
Great new paper highlighting @jenniferepalmer.bsky.social 's PhD work: www.cimr.cam.ac.uk/research-adv...
Reposted by Cambridge Institute for Medical Research
New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
September 10, 2025 at 3:23 PM
New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
@adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social.
journals.biologists.com/jcs/article/...
Reposted by Cambridge Institute for Medical Research
🧠 Cambridge scientist reveals how autophagy clears toxic proteins in neurodegeneration in Genomic Press Interview. Dr. Rubinsztein's breakthrough: cellular cleanup fights Huntington's, Parkinson's & Alzheimer's! 134k+ citations 🔬✨
📄🆓 DOI: doi.org/10.61373/bm0...
Source: genomicpress.kglmeridian.com
📄🆓 DOI: doi.org/10.61373/bm0...
Source: genomicpress.kglmeridian.com
August 21, 2025 at 3:13 PM
🧠 Cambridge scientist reveals how autophagy clears toxic proteins in neurodegeneration in Genomic Press Interview. Dr. Rubinsztein's breakthrough: cellular cleanup fights Huntington's, Parkinson's & Alzheimer's! 134k+ citations 🔬✨
📄🆓 DOI: doi.org/10.61373/bm0...
Source: genomicpress.kglmeridian.com
📄🆓 DOI: doi.org/10.61373/bm0...
Source: genomicpress.kglmeridian.com
Reposted by Cambridge Institute for Medical Research
. @adamrochussen.bsky.social, Claire Ma & Gillian Griffiths @griffithslab.bsky.social find that deletion of Cdc42 in primary T cells triggers transcriptional adaptation, leading to enhanced T cell function.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
August 11, 2025 at 10:56 AM
. @adamrochussen.bsky.social, Claire Ma & Gillian Griffiths @griffithslab.bsky.social find that deletion of Cdc42 in primary T cells triggers transcriptional adaptation, leading to enhanced T cell function.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
Reposted by Cambridge Institute for Medical Research
Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ...
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
August 4, 2025 at 7:31 PM
Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ...
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
Reposted by Cambridge Institute for Medical Research
Great news² 🥳
Clinical PhD student Niki Veale has just passed his PhD viva so will become Dr Dr Veale (Dr² Veale)
We’ve also learned that he’s secured a Clinical Lectureship so will return to the lab as a post-doc (or is that post-doc-doc?)
@thecimr.bsky.social
@veale-n.bsky.social
Clinical PhD student Niki Veale has just passed his PhD viva so will become Dr Dr Veale (Dr² Veale)
We’ve also learned that he’s secured a Clinical Lectureship so will return to the lab as a post-doc (or is that post-doc-doc?)
@thecimr.bsky.social
@veale-n.bsky.social
August 1, 2025 at 4:58 PM
Great news² 🥳
Clinical PhD student Niki Veale has just passed his PhD viva so will become Dr Dr Veale (Dr² Veale)
We’ve also learned that he’s secured a Clinical Lectureship so will return to the lab as a post-doc (or is that post-doc-doc?)
@thecimr.bsky.social
@veale-n.bsky.social
Clinical PhD student Niki Veale has just passed his PhD viva so will become Dr Dr Veale (Dr² Veale)
We’ve also learned that he’s secured a Clinical Lectureship so will return to the lab as a post-doc (or is that post-doc-doc?)
@thecimr.bsky.social
@veale-n.bsky.social
Congratulations Adam!
Delighted to have been awarded a CSAR 2025 PhD Student Award for some of my work in the @griffithslab.bsky.social
@thecimr.bsky.social
The CSAR mission to recognise and prioritise research with real-world application is a super important one that I'll be taking forward as a postdoc & beyond
@thecimr.bsky.social
The CSAR mission to recognise and prioritise research with real-world application is a super important one that I'll be taking forward as a postdoc & beyond
July 24, 2025 at 9:03 AM
Congratulations Adam!
Reposted by Cambridge Institute for Medical Research
New preprint alert! Endogenous gene editing of alveolar organoids to investigate mechanisms of epithelial dysfunction in familial ILD. Kudos first author @eimearrutherford.bsky.social and thanks @thecimr.bsky.social @labrawlins.bsky.social @profmarciniak.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Endogenous gene editing of alveolar organoids reveals that expression of pathogenic variant SFTPC-I73T disrupts endosomal function, epithelial polarity and wound healing
Background: Idiopathic pulmonary fibrosis is a fatal lung disease of progressive lung parenchymal scarring caused by the aberrant response of an alveolar epithelium repeatedly exposed to injury. Under...
www.biorxiv.org
July 22, 2025 at 8:01 PM
New preprint alert! Endogenous gene editing of alveolar organoids to investigate mechanisms of epithelial dysfunction in familial ILD. Kudos first author @eimearrutherford.bsky.social and thanks @thecimr.bsky.social @labrawlins.bsky.social @profmarciniak.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Could climate change bring new diseases to the UK? Prof Michael Weekes spoke to @the-independent.com recently
www.independent.co.uk/climate-chan...
www.independent.co.uk/climate-chan...
Heatwaves could bring deadly ‘tropical’ diseases to Britain
A warming world is pushing tropical infectious diseases northwards as pathogens thrive in hot and humid conditions
www.independent.co.uk
July 17, 2025 at 10:25 AM
Could climate change bring new diseases to the UK? Prof Michael Weekes spoke to @the-independent.com recently
www.independent.co.uk/climate-chan...
www.independent.co.uk/climate-chan...
We had a such a great week with this lovely group of students on @gurdoninstitute.bsky.social ASTP programme- they did some fantastic presentations on Friday! Well done to all of them 👋👋👋
July 15, 2025 at 9:27 AM
We had a such a great week with this lovely group of students on @gurdoninstitute.bsky.social ASTP programme- they did some fantastic presentations on Friday! Well done to all of them 👋👋👋
Reposted by Cambridge Institute for Medical Research
Such a rewarding experience to host these ASTP students and guide them through an exciting weak of science discovery @thecimr.bsky.social
I’m glad I could convey the importance of sterile conditions in cell culture 😂😂
I’m glad I could convey the importance of sterile conditions in cell culture 😂😂
We're loving hosting students for the @gurdoninstitute.bsky.social ASTP programme, along with @mrc-mbu.bsky.social . As ever, so impressed with the next generation of scientists!
July 12, 2025 at 5:31 PM
Such a rewarding experience to host these ASTP students and guide them through an exciting weak of science discovery @thecimr.bsky.social
I’m glad I could convey the importance of sterile conditions in cell culture 😂😂
I’m glad I could convey the importance of sterile conditions in cell culture 😂😂