Tamal Das
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tamaldastifrh.bsky.social
Tamal Das
@tamaldastifrh.bsky.social
3 followers 7 following 1 posts
Associate Professor at TIFR Hyderabad; Exploring the collective dynamics of cells in biology.
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tamaldastifrh.bsky.social
Tamal Das @tamaldastifrh.bsky.social · Sep 18
We study what organelles do - beyond their "textbook" functions - during development and wound healing. Here is a story on how ER morphology shapes cells' response to wound curvature 👇
Reposted by Tamal Das
natcellbio.nature.com
☕🍰Interested in reading more about the study? Here is the N&Vs article written by Roberto Mayor.
👉https://rdcu.be/eJqR1
bit.ly/3IEA38F
Forcing cell fate - Nature Cell Biology
The transition of a pluripotent stem cell into a differentiated lineage is one of the most complex yet precisely orchestrated events in developmental biology. A study now reveals that mechanical and osmotic forces, long considered background players in guiding this transition, are essential regulators of chromatin accessibility and cell fate decisions.
bit.ly
October 4, 2025 at 2:40 PM
Reposted by Tamal Das
natcellbio.nature.com
🎃Our October issue's out!
Cover: mechanoresponsive #microtubules

👉🏼Reviews: #CellularStress ; #NuclearPoreComplex & #mechanobiology
🔬 #StemCells #senescence #cancer #EndoplasmicReticulum #phagocytosis #pyroptosis #autophagy #PhaseSeparation #AMPK #chromatin & more!
www.nature.com/ncb/volumes/...
October 17, 2025 at 10:25 AM
Reposted by Tamal Das
fabianspill.bsky.social
Thanks Craig Blackstone for the news & views @natcellbio.nature.com about our article thats shows how ER shape and mechanics determine the mode of cell migration. Collaboration with Simran, Pradeep and @tamaldastifrh.bsky.social. rdcu.be/eJZWf
ER shaping closes the gap in wound healing
Nature Cell Biology - During wound healing, epithelial gaps trigger curvature-dependent ER remodelling. Tubules form at convex cell edges and promote lamellipodial crawling, whereas ER sheets at...
rdcu.be
October 8, 2025 at 9:37 AM
Reposted by Tamal Das
cohenlaboratory.bsky.social
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
September 17, 2025 at 5:38 PM
Reposted by Tamal Das
fabianspill.bsky.social
Great collaboration on uncovering how ER organisation, curvature and mechanics are regulating collective cell migration. Experiments by Simran, Tamal and collaborators and a model by Pradeep.
September 8, 2025 at 7:40 PM
tamaldastifrh.bsky.social
We study what organelles do - beyond their "textbook" functions - during development and wound healing. Here is a story on how ER morphology shapes cells' response to wound curvature 👇
September 18, 2025 at 10:27 AM