The Stoiber Lab
@stoiberlab.bsky.social
The Dagmar Stoiber-Sakaguchi Lab is focused on molecular mechanisms underlying hematopoietic tumor development and progression.
#AML #JAK-STAT #MPN #STAT3
#AML #JAK-STAT #MPN #STAT3
Reposted by The Stoiber Lab
Nature research paper: STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity
https://go.nature.com/4dhenKu
https://go.nature.com/4dhenKu
STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity - Nature
Immune checkpoint blockade activates T cell immunity by reprogramming the STAT3 and STAT5 transcriptional pathways in dendritic cells, and STAT3 degradation is effective for treating tumours of multiple cancer types in mouse models.
go.nature.com
May 19, 2025 at 9:40 AM
Nature research paper: STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity
https://go.nature.com/4dhenKu
https://go.nature.com/4dhenKu
Reposted by The Stoiber Lab
‼️Our latest study, “Loss of STAT3 in acute myeloid leukemia favors tissue infiltration linked to CXCR4 signaling,” is now out in @bloodneoplasia.bsky.social
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
October 15, 2025 at 2:53 PM
‼️Our latest study, “Loss of STAT3 in acute myeloid leukemia favors tissue infiltration linked to CXCR4 signaling,” is now out in @bloodneoplasia.bsky.social
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...