Timothy Stiles
@stiles.io
Genetic, research, and software engineer looking to make friends.
Creator of Poly, an open source Go package for engineering DNA 🧬
Let's engineer weird little guys together.
github.com/bebop/poly
📍San Francisco
Creator of Poly, an open source Go package for engineering DNA 🧬
Let's engineer weird little guys together.
github.com/bebop/poly
📍San Francisco
Pinned
Timothy Stiles
@stiles.io
· Nov 9
Made a biotech starter pack because I want to meme with y'all on this site instead of the old one
go.bsky.app/TbKxUEk 🧪🧬💻
go.bsky.app/TbKxUEk 🧪🧬💻
Does anyone know where I can get a COVID vaccine in the Bay Area?
Spoken to two pharmacists now saying that they don't have any and that they're on hold in a warehouse somewhere but I need one now...
Spoken to two pharmacists now saying that they don't have any and that they're on hold in a warehouse somewhere but I need one now...
September 10, 2025 at 8:36 PM
Does anyone know where I can get a COVID vaccine in the Bay Area?
Spoken to two pharmacists now saying that they don't have any and that they're on hold in a warehouse somewhere but I need one now...
Spoken to two pharmacists now saying that they don't have any and that they're on hold in a warehouse somewhere but I need one now...
What it feels like to set up a GPU node for your home computing cluster
July 22, 2025 at 8:45 AM
What it feels like to set up a GPU node for your home computing cluster
Got a 404 for all of a second when trying to look something up on Wikipedia and my heart stopped
July 21, 2025 at 12:16 AM
Got a 404 for all of a second when trying to look something up on Wikipedia and my heart stopped
Market Basket has a stronger fan base in New England than the Red Sox and it's not close
Market Basket CEO Arthur T. Demoulas suspended. He calls it a "hostile takeover."
Market Basket CEO Arthur T. Demoulas has been suspended while his conduct is investigated by the company's board.
www.cbsnews.com
June 27, 2025 at 10:19 PM
Market Basket has a stronger fan base in New England than the Red Sox and it's not close
It's only been 6 weeks since we got a new pope from Chicago and it feels so long ago
June 26, 2025 at 7:37 AM
It's only been 6 weeks since we got a new pope from Chicago and it feels so long ago
I scored a fancy air fryer for 12 bucks at the thrift store what should I put in it?
June 26, 2025 at 3:26 AM
I scored a fancy air fryer for 12 bucks at the thrift store what should I put in it?
I know almost two dozen languages and barely remember how to write a for loop in any of them
The final evolution of software engineer is knowing so many programming languages that you can't code in any of them and have to Google basic syntax.
June 23, 2025 at 10:04 PM
I know almost two dozen languages and barely remember how to write a for loop in any of them
Reposted by Timothy Stiles
The final evolution of software engineer is knowing so many programming languages that you can't code in any of them and have to Google basic syntax.
June 23, 2025 at 9:39 PM
The final evolution of software engineer is knowing so many programming languages that you can't code in any of them and have to Google basic syntax.
The only orange muppet to trust about science.
June 14, 2025 at 9:00 PM
The only orange muppet to trust about science.
So many people my phone lost service and cars have completely given up crossing Market Street with some honking or even getting out of their cars in support.
June 14, 2025 at 8:38 PM
So many people my phone lost service and cars have completely given up crossing Market Street with some honking or even getting out of their cars in support.
People passing by me at ~20 people per second. This has been going at a similar rate for ~30 minutes and shows no signs of stopping.
June 14, 2025 at 7:42 PM
People passing by me at ~20 people per second. This has been going at a similar rate for ~30 minutes and shows no signs of stopping.
There's so many people here that the cell phone towers nearby can't handle the traffic and my phone is struggling to post pictures.
June 14, 2025 at 7:34 PM
There's so many people here that the cell phone towers nearby can't handle the traffic and my phone is struggling to post pictures.
I've never seen this many people at Dolores park
June 14, 2025 at 7:32 PM
I've never seen this many people at Dolores park
Reposted by Timothy Stiles
The war on science in the US is already having an effect on private sector research like AlphaFold. Bears repeating but the private sector builds on top of things created by academic research for the public good. This hurts everyone.
May 28, 2025 at 10:18 AM
The war on science in the US is already having an effect on private sector research like AlphaFold. Bears repeating but the private sector builds on top of things created by academic research for the public good. This hurts everyone.
Reposted by Timothy Stiles
HMMER is the bedrock of genomic annotation globally, and now its funding is terminated for no reason.
@cryptogenomicon.bsky.social is now on bsky:
@cryptogenomicon.bsky.social is now on bsky:
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 28, 2025 at 4:25 PM
HMMER is the bedrock of genomic annotation globally, and now its funding is terminated for no reason.
@cryptogenomicon.bsky.social is now on bsky:
@cryptogenomicon.bsky.social is now on bsky:
Reposted by Timothy Stiles
HMMER is crucial to our modern understanding of protein biochemistry and has almost certainly generated at least a 10-fold return on investment for every dollar the US government has spent on funding it.
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 28, 2025 at 4:26 PM
HMMER is crucial to our modern understanding of protein biochemistry and has almost certainly generated at least a 10-fold return on investment for every dollar the US government has spent on funding it.
Reposted by Timothy Stiles
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 22, 2025 at 12:42 PM
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
In my day people read the abstract when they wanted to pretend to be smart.
This sucks so much man, I’m begging people to just read papers and think with their own brain. Why are you even in this profession otherwise?
May 10, 2025 at 10:36 PM
In my day people read the abstract when they wanted to pretend to be smart.
Chicago style pizza in the Vatican is now cannon.
May 8, 2025 at 5:17 PM
Chicago style pizza in the Vatican is now cannon.
Colossal bio guys have gone too far.
This is what happens when you try to make penguins fly. They're flightless for a reason.
This is what happens when you put tariffs on penguins.
April 12, 2025 at 7:56 PM
Colossal bio guys have gone too far.
This is what happens when you try to make penguins fly. They're flightless for a reason.
April 12, 2025 at 7:55 PM
This is what happens when you try to make penguins fly. They're flightless for a reason.
This is such a crackpot idea but has anyone run for Congress on the explicit promise that they will insider trade and use the profits to set up a wealth fund for their district?
April 10, 2025 at 3:51 PM
This is such a crackpot idea but has anyone run for Congress on the explicit promise that they will insider trade and use the profits to set up a wealth fund for their district?
If you have a free tech or biotech event in the Bay Area that doesn't feature pizza, beer, and AI I will advertise tf out of it
For almost a decade broke recent college grads in hubs like Boston and SF could eat for free and network almost every night as long as they didn't hit their pizza toxicity threshold.
That's no longer the case and I wrote a little about what happened and why I want this back.
That's no longer the case and I wrote a little about what happened and why I want this back.
March 18, 2025 at 6:06 PM
If you have a free tech or biotech event in the Bay Area that doesn't feature pizza, beer, and AI I will advertise tf out of it