Steve Quinn
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Steve Quinn
@steve-quinn-lab.bsky.social
Single molecule biophysicist at the University of York, UK. Alzheimer’s disease, biophotonics, diagnostics, protein-membrane interactions, smFRET.
Pinned
🚨Only 2 more weeks to apply for our fully-funded PhD position @york.ac.uk! Want to pioneer a blood test for dementia, detect single molecules & spend time in industry with
@ei-science.bsky.social?! Apply by 4th Dec:
tinyurl.com/yt36p9tx
It doesn't get any more EXCITING! 🔬🩸🧪
🚨Only 2 more weeks to apply for our fully-funded PhD position @york.ac.uk! Want to pioneer a blood test for dementia, detect single molecules & spend time in industry with
@ei-science.bsky.social?! Apply by 4th Dec:
tinyurl.com/yt36p9tx
It doesn't get any more EXCITING! 🔬🩸🧪
November 17, 2025 at 11:44 AM
Reposted by Steve Quinn
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social

www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
November 9, 2025 at 5:20 PM
🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @york.ac.uk
! Find out more & apply by 4th Dec:

tinyurl.com/yt36p9tx

@ybri-uoy.bsky.social @ei-science.bsky.social @timcraggs.bsky.social
October 31, 2025 at 4:14 PM
We are delighted that our latest @york.ac.uk & @ybri-uoy.bsky.social work showcasing our photonic biosensor for Alzheimer's disease blood biomarkers has been published in @optica.org!
👇
opg.optica.org/optica/fullt...

Thanks to @alzheimerssoc.bsky.social & @alzheimersresearchuk.org for support!
Optica Publishing Group
opg.optica.org
October 2, 2025 at 7:04 PM
Congratulations to Dr Fran D'Rozario from our @york.ac.uk team for successfully defending her thesis! Thanks also to Prof Paula Mendes & @bpsiyork.bsky.social for examining, and to Prof Steve Johnson for supervising. Well done Fran!
a congratulations card with a graduation cap
ALT: a congratulations card with a graduation cap
media.tenor.com
September 29, 2025 at 4:49 PM
New preprint! 🚨 I'm delighted to share our latest @york.ac.uk & @ybri-uoy.bsky.social pre-print: "Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching." Congratulations to Claudia from the team on her first manuscript!
👇👇
www.biorxiv.org/content/10.1...
Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching
Detergent-induced membrane solubilization is important for several biotechnological applications including membrane protein isolation, cell lysis and virus inactivation. The thermodynamic details of t...
www.biorxiv.org
September 29, 2025 at 9:38 AM
We are delighted to announce that our latest work - a handheld photonic biosensor for Alzheimer's disease blood biomarkers - has been accepted for publication in Optica! Check out the pre-print...
👇👇
arxiv.org/abs/2504.08476
...and BBC story below:
www.bbc.co.uk/news/uk-engl...
arxiv.org
August 19, 2025 at 4:50 PM
🚨 New preprint!🚨We introduce a DNA-scaffold strategy for efficient dye labelling of structured RNAs, enabling #smFRET studies of freely-diffusing SARS-CoV-2 pseudoknots🧬
👉 biorxiv.org/content/10.1...

#smFRET #RNA #biophysics #SARSCoV2 #singlemolecule #Covid
A DNA scaffold approach facilitates 5′ labelling of the SARS-CoV-2 RNA pseudoknot for smFRET investigation
Single-molecule Förster resonance energy transfer (smFRET) studies of highly structured RNA molecules are often frustrated by issues with efficient dye conjugation. Here, we develop a DNA scaffold-bas...
biorxiv.org
July 30, 2025 at 9:16 AM
🧬New Pre-Print!🧬 PhD candidate Fran D'Rozario explores how pH-sensitive DNA triplexes retain reversible switching in solution, and when densely immobilized on surfaces - a step towards hybrid electronic DNA devices?
👇👇
biorxiv.org/content/10.1...

#DNAnanotech #bioelectronics #smFRET #DNAmachines
Electronic Actuation of Surface-Immobilized, pH-Responsive DNA Nanoswitches
Dynamic DNA machines exploit the specificity of base pairing and/or sensitivity to the local environment to control the reversible switching of DNA constructs between conformational states. One such e...
biorxiv.org
July 28, 2025 at 2:19 PM
New job opportunity! The Lindemann Trust
is recruiting 2 freelance roles: a Trusts and Grants Fundraiser and Philanthropy Events Fundraiser. For more info, and to apply, visit:
lindemanntrust.co.uk/support/
Closing date: Tuesday 19th August.
Support - The Lindemann Fellowship Administrative Trust
Support If you are interested in supporting our activities, either through sponsorship or by volunteering your time, we would love to hear from you. Below are just a few examples of ways you might be ...
lindemanntrust.co.uk
July 23, 2025 at 11:47 AM
🚨New Preprint! Latest research led by
@jemmabetts.bsky.social & @chillzaa.bsky.social
reveals the structure of a protein-dependent riboswitch, revealing new mechanistic principles that could inspire novel antivirals! Thanks @ukri.org, @ei-science.bsky.social, @ybri-uoy.bsky.social for support! 🔬
July 21, 2025 at 9:45 AM
Congratulations to Dr Sarah Graham @york.ac.uk #Physicsoflife group for successfully defending her thesis!
Thanks also to Dr Tara Sabir & @agnesnoy.bsky.social for doing the honours as examiners, @bpsiyork.bsky.social for co-supervising & @chillzaa.bsky.social for all the help along the way!
a cartoon of snoopy jumping with the words yay congratulations below him
ALT: a cartoon of snoopy jumping with the words yay congratulations below him
media.tenor.com
June 2, 2025 at 12:49 PM
The heat was brutal, and the second half was gruelling. So chuffed to have made it through the 26.2 miles! Thanks London and @alzheimersresearchuk.org that was a blast!
April 27, 2025 at 7:09 PM
26.2 hours until until I take on #londonmarathon2025 , running for @AlzResearchUK ! Every step is for a future free from dementia. Let’s do this!

justgiving.com/page/runlabrun
April 26, 2025 at 10:55 AM
We are excited to share our latest pre-print, now available on
@arxiv.bsky.social: our latest photonic biosensing platform for blood-based Alzheimer's Disease biomarker detection!

Check it out! 👇👇
arxiv.org/abs/2504.08476

@ybri-uoy.bsky.social
Ultrasensitive Alzheimer's Disease Biomarker Detection with Nanopillar Photonic Crystal Biosensors
The recent development of drugs able to mitigate neurodegenerative diseases has created an urgent need for novel diagnostics. Although biomarker detection directly in patients' blood is now possible, ...
arxiv.org
April 14, 2025 at 12:35 PM
It’s finally time for the taper! My legs are delighted to share that they have completed the final long training run! London Marathon 2025 is just 2 weeks away! #inpain 🏃

Donations to @alzheimersresearchuk.org , who fund critical research are enormously appreciated!

justgiving.com/page/runlabrun
Steve's fundraiser for Alzheimer's Research UK
Help Steven Quinn raise money to support Alzheimer's Research UK
justgiving.com
April 13, 2025 at 4:13 PM
Blood biomarkers are beginning to revolutionize #Alzheimers diagnosis and have potential to offer early detection. Could emerging blood test technologies transform patiet care?

Check out my editorial, out now in @jprecmed.bsky.social
👇👇
tinyurl.com/nwk34t7k

#Biomarkers #Dementia #Diagnostics
The Urgent and Global Need for Democratized Blood-Based Biomarker Diagnostics in Alzheimer’s Disease
Alzheimer’s disease (AD) represents one of the most pressing healthcare challenges of the 21st century. As a leading cause of dementia, AD impacts over 55 million people worldwide, with this number pr...
tinyurl.com
March 19, 2025 at 11:53 AM
Excited to be running #londonmarathon 2025 in support of @alzheimersresearchuk.org! The charity does so much to support ground-breaking dementia research! Any support for their mission, however small, would be massively appreciated and treasured so much!

www.justgiving.com/page/runlabrun
March 10, 2025 at 7:15 PM
Reposted by Steve Quinn
🚨 Exciting Seminar coming up!

→ Unravelling the FLEXibility of DNA hairpins and novel RNA systems

with @timcraggs.bsky.social , Hermia Kung and @steve-quinn-lab.bsky.social

⏰ 11th March 2025 | 5 PM BST (12 PM ET)

🔥 Bonus: A roundtable discussion!

Register here: buff.ly/J5P2J8s
March 4, 2025 at 12:54 PM
We’re on the way to #Birmingham for #ARUKConf2025! Excited to showcase our latest tech for blood based biomarker analysis and learn more about the latest developments in #dementia research! Come chat with us - we’re a friendly bunch! 🔬📈📊🥼
February 24, 2025 at 12:27 PM
Reposted by Steve Quinn
We're all set for @biophysicalsoc.bsky.social
#bps2025! Come learn more about our team's biosensing innovations for blood-based biomarker detection! Katie will showcase a new nanopillar-based approach for multiplexed analysis of Alzheimer's biomarkers! Sunday Feb 16th @ 9.45! 📊🩸🧪
February 7, 2025 at 9:03 AM
We're all set for @biophysicalsoc.bsky.social
#bps2025! Come learn more about our team's biosensing innovations for blood-based biomarker detection! Katie will showcase a new nanopillar-based approach for multiplexed analysis of Alzheimer's biomarkers! Sunday Feb 16th @ 9.45! 📊🩸🧪
February 7, 2025 at 9:03 AM
Reposted by Steve Quinn
🚨 I'm delighted to announce a fully-funded PhD studentship (October 2025 entry) in collaboration with the Pirbright Institute.

Are you interested in FMDV genome replication and packaging? Fascinated by structure and RNA-protein interactions? More info here:

www.findaphd.com/phds/project...
Probing the Function of RNA Structural Elements in the FMDV Genome using Biophysical and Genetic Approaches at The Pirbright Institute on FindAPhD.com
PhD Project - Probing the Function of RNA Structural Elements in the FMDV Genome using Biophysical and Genetic Approaches at The Pirbright Institute, listed on FindAPhD.com
www.findaphd.com
January 20, 2025 at 11:12 AM
Our latest work showcasing a resonant Young's slit interferometric biosensor for the ultrasensitive detection of Alzheimer's disease biomarkers has been accepted for publication! Congrats to Stefanus, Katie & Augusto from the team! Thanks to @alzheimerssoc.bsky.social & @york.ac.uk for support! 🔬🧪
January 10, 2025 at 9:55 AM
Reposted by Steve Quinn
Still time to apply for this PhD project with the awesome 🙌 @steve-quinn-lab.bsky.social, @georgerheath.bsky.social and me.

By the way, York is a beautiful 🤩 historic city!
Please repost, grazie 😊 🌷.
📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.

Supervised by me, @Steve Quinn & @georgerheath.bsky.social

www.findaphd.com/phds/project...
Open to Applicants Worldwide!

📅 January 6, 2025

#microsky #archaeasky
December 18, 2024 at 7:14 PM