Stephanie Xie
@stephxie.bsky.social
Firstgen immigrant scientist, mom and partner.
Studying metabolic and inflammatory heterogeneity in🩸and leukemia stem cells.
Allan Slaight Scientist@Princess Margaret Cancer Centre
Assistant Prof@UofToronto
avid orchid lover. 🇺🇸 🇨🇦citizen.
Studying metabolic and inflammatory heterogeneity in🩸and leukemia stem cells.
Allan Slaight Scientist@Princess Margaret Cancer Centre
Assistant Prof@UofToronto
avid orchid lover. 🇺🇸 🇨🇦citizen.
First trip to Weatern Canada for ECR workshop and #CCRC2025 in #Calgary. Terrific time making new connections in #cancerresearch and reconnecting with colleagues @pmresearch-uhn.bsky.social @sickkidsto.bsky.social.
November 4, 2025 at 11:19 PM
First trip to Weatern Canada for ECR workshop and #CCRC2025 in #Calgary. Terrific time making new connections in #cancerresearch and reconnecting with colleagues @pmresearch-uhn.bsky.social @sickkidsto.bsky.social.
What a wonderful place to be…
October 23, 2025 at 4:34 PM
What a wonderful place to be…
I’m thrilled to be speaking at the Erasmus Hematology Lecture series, Monday Sept 15th. Grateful to @elsdutchy.bsky.social for the invite.
Start: 16.00h /04.00 pm CE(S)T - 10.00 am ET - 09.00 am CT
Zoom ID: 844 1856 0786
www.hematologyrotterdam.nl/2626141_the-...
Start: 16.00h /04.00 pm CE(S)T - 10.00 am ET - 09.00 am CT
Zoom ID: 844 1856 0786
www.hematologyrotterdam.nl/2626141_the-...
The new fall lecture series! | Department of Hematology
The Erasmus MC Hematology Department is excited to announce our new fall lecture series!
Starting on September 1st, there will be webinars from excellent researchers covering a wide range of hematolo...
www.hematologyrotterdam.nl
September 14, 2025 at 10:29 PM
I’m thrilled to be speaking at the Erasmus Hematology Lecture series, Monday Sept 15th. Grateful to @elsdutchy.bsky.social for the invite.
Start: 16.00h /04.00 pm CE(S)T - 10.00 am ET - 09.00 am CT
Zoom ID: 844 1856 0786
www.hematologyrotterdam.nl/2626141_the-...
Start: 16.00h /04.00 pm CE(S)T - 10.00 am ET - 09.00 am CT
Zoom ID: 844 1856 0786
www.hematologyrotterdam.nl/2626141_the-...
Bye-Bye Bay of Fundy. See you next year.
August 23, 2025 at 11:17 AM
Bye-Bye Bay of Fundy. See you next year.
The quiet beauty of a Sunday morning overlooking St Mary’s Bay. #nofiltersneeded #familyvacation
August 17, 2025 at 2:04 PM
The quiet beauty of a Sunday morning overlooking St Mary’s Bay. #nofiltersneeded #familyvacation
Reposted by Stephanie Xie
Check out our new preprint on an epigenetic resistance mechanism to PI3 kinase inhibition in AML and a new combination therapy with an EZH1/2 inhibitor that depletes leukemic stem cells! Great effort by @thehematopoet and the whole team
So excited to share a pre-print of my thesis work! Check it out to see how we can leverage an epigenetic resistance mechanism to PI3K inhibitors to target leukemic stem cells!! (Spoiler alert: PRC2 is involved!) Really proud of this work conducted with @gritsmanlab.bsky.social
Exploiting an Epigenetic Resistance Mechanism to PI3 Kinase Inhibition in Leukemic Stem Cells https://www.biorxiv.org/content/10.1101/2025.07.11.663968v1
July 16, 2025 at 1:45 AM
Check out our new preprint on an epigenetic resistance mechanism to PI3 kinase inhibition in AML and a new combination therapy with an EZH1/2 inhibitor that depletes leukemic stem cells! Great effort by @thehematopoet and the whole team
Reposted by Stephanie Xie
The Myeloid Workshop is back in ASH! Please contact the organizers if you have an exciting story that will not be out by December they are: Zuzana Tothova ,
@ernstlaboratory.bsky.social
@steidluli.bsky.social
@ericpietras.bsky.social
@kathrinbernt.bsky.social
@gritsmanlab.bsky.social
@ernstlaboratory.bsky.social
@steidluli.bsky.social
@ericpietras.bsky.social
@kathrinbernt.bsky.social
@gritsmanlab.bsky.social
July 21, 2025 at 7:27 PM
The Myeloid Workshop is back in ASH! Please contact the organizers if you have an exciting story that will not be out by December they are: Zuzana Tothova ,
@ernstlaboratory.bsky.social
@steidluli.bsky.social
@ericpietras.bsky.social
@kathrinbernt.bsky.social
@gritsmanlab.bsky.social
@ernstlaboratory.bsky.social
@steidluli.bsky.social
@ericpietras.bsky.social
@kathrinbernt.bsky.social
@gritsmanlab.bsky.social
Travel grants for trainees are available for the stellar FEBS Workshop on Aging in Hematopoiesis that will take place in Crete on October 20-24. Deadline for applications: July 31. More info: aginginhematopoiesis2025.febsevents.org/travel-grants
July 2, 2025 at 2:45 PM
Travel grants for trainees are available for the stellar FEBS Workshop on Aging in Hematopoiesis that will take place in Crete on October 20-24. Deadline for applications: July 31. More info: aginginhematopoiesis2025.febsevents.org/travel-grants
So proud of Team Stemmy! Interdisciplinary collabs are the way to make a difference for preventing and curing cancer. @pmresearch-uhn.bsky.social @uwaterloo.ca
Three Waterloo grads — Isabella Di Biasio, Veronika Sustrova and Katarina Makivic — teamed up to automate blood stem cell analysis using ML and a custom scripting language. Their tool, developed with Princess Margaret Cancer Centre, aims to speed up cancer research.
cs.uwaterloo.ca/news/biochem...
cs.uwaterloo.ca/news/biochem...
June 26, 2025 at 1:02 AM
So proud of Team Stemmy! Interdisciplinary collabs are the way to make a difference for preventing and curing cancer. @pmresearch-uhn.bsky.social @uwaterloo.ca
Those in #Milan for #EHA2025, catch Angelica Varesi in her oral on this story live.
🎤 "Discovery of ATP2B1+ CD49f+ Human Hematopoietic Stem Cells with Superior Long-term Multilineage Reconstitution"
🗓 Thursday, June 12 | 🕔 17:00–17:15 CEST
📍 Brown Hall 1
🎤 "Discovery of ATP2B1+ CD49f+ Human Hematopoietic Stem Cells with Superior Long-term Multilineage Reconstitution"
🗓 Thursday, June 12 | 🕔 17:00–17:15 CEST
📍 Brown Hall 1
Preprint alert🚨‼️
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
ATP2B1 expression identifies human hematopoietic stem cells across… | Stephanie Xie
Those in #Milan for #EHA2025, catch Angelica Varesi in her oral on this story live.
🎤 "Discovery of ATP2B1+ CD49f+ Human Hematopoietic Stem Cells with Superior Long-term Multilineage Reconstitu...
www.linkedin.com
June 11, 2025 at 4:50 PM
Preprint alert🚨‼️
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
ATP2B1 expression identifies human hematopoietic stem cells across… | Stephanie Xie
Those in #Milan for #EHA2025, catch Angelica Varesi in her oral on this story live.
🎤 "Discovery of ATP2B1+ CD49f+ Human Hematopoietic Stem Cells with Superior Long-term Multilineage Reconstitu...
www.linkedin.com
June 11, 2025 at 4:49 PM
Preprint alert🚨‼️
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. @pmresearch-uhn.bsky.social #teamscience
This month has been a whirlwind. I am happy to announce I am the newest Scientist @pmresearch-uhn.bsky.social
The Xie lab 🧪will focus on understanding how inflammatory and metabolic stress promote aging and cancer risk in human🩸hematopoietic stem cells and preventative interventions.
The Xie lab 🧪will focus on understanding how inflammatory and metabolic stress promote aging and cancer risk in human🩸hematopoietic stem cells and preventative interventions.
April 30, 2025 at 12:56 PM
This month has been a whirlwind. I am happy to announce I am the newest Scientist @pmresearch-uhn.bsky.social
The Xie lab 🧪will focus on understanding how inflammatory and metabolic stress promote aging and cancer risk in human🩸hematopoietic stem cells and preventative interventions.
The Xie lab 🧪will focus on understanding how inflammatory and metabolic stress promote aging and cancer risk in human🩸hematopoietic stem cells and preventative interventions.
This is the most deserving of honors. Congratulations to my long-time mentor Dr. John Dick!
Congratulations to Dr. John Dick, Senior Scientist at UHN’s
@pmresearch-uhn.bsky.social, on his election to the National Academy of Sciences, one of the highest honours for a scientist.
@pmresearch-uhn.bsky.social, on his election to the National Academy of Sciences, one of the highest honours for a scientist.
April 30, 2025 at 4:37 AM
This is the most deserving of honors. Congratulations to my long-time mentor Dr. John Dick!
Reposted by Stephanie Xie
Congratulations to our Senior Scientist Dr. John Dick on being elected into the National Academy of Sciences. @nationalacademies.org
A huge congratulations to Dr. John Dick @pmresearch-uhn.bsky.social @uhntoronto.bsky.social who has been elected into the National Academy of Sciences @nationalacademies.org as an International member today. www.nasonline.org
National Academy of Sciences
The National Academy of Sciences (NAS) is a private, nonprofit organization of the country’s leading researchers, recognizing and promoting outstanding science.
www.nasonline.org
April 29, 2025 at 7:41 PM
Congratulations to our Senior Scientist Dr. John Dick on being elected into the National Academy of Sciences. @nationalacademies.org
Reposted by Stephanie Xie
Congratulations @stephxie.bsky.social already a star @uhntoronto.bsky.social @pmresearch-uhn.bsky.social
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...
April 26, 2025 at 6:19 PM
Congratulations @stephxie.bsky.social already a star @uhntoronto.bsky.social @pmresearch-uhn.bsky.social
@aircanada.bsky.social Please get your act together. I will miss the plenary session of #AACR2025 and learn about groundbreaking cancer research because my flight got canceled 20 minutes before boarding. Unexpected mechanical failure. Last month too. That’s an awful trend.
April 26, 2025 at 6:16 PM
@aircanada.bsky.social Please get your act together. I will miss the plenary session of #AACR2025 and learn about groundbreaking cancer research because my flight got canceled 20 minutes before boarding. Unexpected mechanical failure. Last month too. That’s an awful trend.
Reposted by Stephanie Xie
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...
April 26, 2025 at 4:18 PM
This year’s 11 NextGen Stars will share their findings on cancer cartography, the dark proteome, cancer-resistant tissues, and more at #AACR25. Learn more about their work and its future implications on the #AACRBlog: www.aacr.org/blog/2025/04...
I had so much fun. 🙏@eirinipapapetrou.bsky.social, Elvin Wagenblast, Chris Sturgeon, Franco Izzo for the hospitality @sinaiirm.bsky.social
A 2 for 1 visit with insightful feedback from the Leukemia Working Group.
A 2 for 1 visit with insightful feedback from the Leukemia Working Group.
Learned all about HSC-iMs and had a great time with @stephxie.bsky.social in NYC. Thank you for visiting us Steph! @kharaslab.bsky.social @gritsmanlab.bsky.social
April 10, 2025 at 1:15 PM
I had so much fun. 🙏@eirinipapapetrou.bsky.social, Elvin Wagenblast, Chris Sturgeon, Franco Izzo for the hospitality @sinaiirm.bsky.social
A 2 for 1 visit with insightful feedback from the Leukemia Working Group.
A 2 for 1 visit with insightful feedback from the Leukemia Working Group.
Still a New Yorker at heart. I love the skyline of my childhood city. Looking forward to talking 🩸🧪science with colleagues at Icahn Mount Sinai and MSKCC and seeing family.
April 8, 2025 at 8:04 PM
Still a New Yorker at heart. I love the skyline of my childhood city. Looking forward to talking 🩸🧪science with colleagues at Icahn Mount Sinai and MSKCC and seeing family.
Huge congratulations to @danieljdrucker.bsky.social and fellow scientists for the Breakthrough Prize in Life Sciences on the 🧪discoveries leading to development of GLP1R agonists. www.theglobeandmail.com/canada/artic...
Canadian scientist Daniel Drucker among winners of Breakthrough Prize for discovery of hormone used in anti-obesity drugs
Senior investigator at Mount Sinai Hospital was one of five researchers jointly awarded US$3-million in world’s largest science prize
www.theglobeandmail.com
April 6, 2025 at 4:54 PM
Huge congratulations to @danieljdrucker.bsky.social and fellow scientists for the Breakthrough Prize in Life Sciences on the 🧪discoveries leading to development of GLP1R agonists. www.theglobeandmail.com/canada/artic...
I am thrilled to be included with this amazing group of scientists as part of the 2025 AACR NextGen Stars. Here are the challenges and future 🧪directions we have identified in our respective areas of cancer research. doi.org/10.1158/2159...
Insights on Future Directions in Cancer Research from the 2025 AACR NextGen Stars
The AACR NextGen Stars program recognizes and supports visionary early-career scientists pushing the boundaries of cancer research. In this set of commentaries, the 2025 NextGen Stars discuss the chal...
doi.org
April 3, 2025 at 5:39 PM
I am thrilled to be included with this amazing group of scientists as part of the 2025 AACR NextGen Stars. Here are the challenges and future 🧪directions we have identified in our respective areas of cancer research. doi.org/10.1158/2159...
Registration for the 2025 FEBS Workshop on the Molecular and Cellular Pathways of Aging in Hematopoiesis in Crete on October 20-24 is live! Check out the amazing lineup of invited speakers on normal and malignant 🩸🧪, CH, inflammation, niche and much more. lnkd.in/eamN_YHs
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
March 18, 2025 at 8:09 PM
Registration for the 2025 FEBS Workshop on the Molecular and Cellular Pathways of Aging in Hematopoiesis in Crete on October 20-24 is live! Check out the amazing lineup of invited speakers on normal and malignant 🩸🧪, CH, inflammation, niche and much more. lnkd.in/eamN_YHs
Reposted by Stephanie Xie
Bluetorial: Women, courage, and leadership
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
March 9, 2025 at 4:33 AM
Bluetorial: Women, courage, and leadership
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
important study of 🩸#stemcells in aging mice. huge translational opportunities for decreasing cancer risk if we can uncover the mechanisms underlying HSC clonal dynamics differences from humans. Kudos to @goodell-lab.bsky.social
@seungchii.bsky.social
@seungchii.bsky.social
Delighted to share my PhD thesis work is now published in @nature.com! This study tracks the journey of blood stem cells in aging mice, examining how the clonal dynmics of blood production change over time. A short 🧵1/n #aging #stemcells #clonalhematopoiesis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Clonal dynamics and somatic evolution of haematopoiesis in mouse - Nature
Isolating and studying haematopoietic stem cells in young and aged mice demonstrates evolutionary processes related to blood production and provides a framework for interpreting future work using labo...
www.nature.com
March 7, 2025 at 1:25 AM
important study of 🩸#stemcells in aging mice. huge translational opportunities for decreasing cancer risk if we can uncover the mechanisms underlying HSC clonal dynamics differences from humans. Kudos to @goodell-lab.bsky.social
@seungchii.bsky.social
@seungchii.bsky.social