Sachin Kotak
@spindlebehavior.bsky.social
Cell Biologist interested in fundamental cell division processes working @iiscbangalore
Pinned
Sachin Kotak
@spindlebehavior.bsky.social
· Sep 13
Happy to share our work in @embojournal 👉 shorturl.at/zXNyn
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division?
Follow this thread to know more 👇
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division?
Follow this thread to know more 👇
Reposted by Sachin Kotak
New Aurora A kinase role in maintaining proper nuclear shape organization at mitotic exit:
NuMA inhibition causes its dynamic-to-solid material-state transition, leading to bending of segregated mitotic chromosomes
Sachin Kotak @spindlebehavior.bsky.social et al
www.embopress.org/doi/full/10....
NuMA inhibition causes its dynamic-to-solid material-state transition, leading to bending of segregated mitotic chromosomes
Sachin Kotak @spindlebehavior.bsky.social et al
www.embopress.org/doi/full/10....
September 19, 2025 at 7:49 AM
New Aurora A kinase role in maintaining proper nuclear shape organization at mitotic exit:
NuMA inhibition causes its dynamic-to-solid material-state transition, leading to bending of segregated mitotic chromosomes
Sachin Kotak @spindlebehavior.bsky.social et al
www.embopress.org/doi/full/10....
NuMA inhibition causes its dynamic-to-solid material-state transition, leading to bending of segregated mitotic chromosomes
Sachin Kotak @spindlebehavior.bsky.social et al
www.embopress.org/doi/full/10....
Happy to share our work in @embojournal 👉 shorturl.at/zXNyn
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division?
Follow this thread to know more 👇
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division?
Follow this thread to know more 👇
September 13, 2025 at 5:14 AM
Happy to share our work in @embojournal 👉 shorturl.at/zXNyn
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division?
Follow this thread to know more 👇
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division?
Follow this thread to know more 👇
Reposted by Sachin Kotak
It’s happening on the 15th!!
#centrosome, #microtubules, #centromere, #mitosis, #cellbiology
@kaustuvsanyal.bsky.social
@viji-draviam.bsky.social
@spindlebehavior.bsky.social
#centrosome, #microtubules, #centromere, #mitosis, #cellbiology
@kaustuvsanyal.bsky.social
@viji-draviam.bsky.social
@spindlebehavior.bsky.social
July 9, 2025 at 4:09 PM
It’s happening on the 15th!!
#centrosome, #microtubules, #centromere, #mitosis, #cellbiology
@kaustuvsanyal.bsky.social
@viji-draviam.bsky.social
@spindlebehavior.bsky.social
#centrosome, #microtubules, #centromere, #mitosis, #cellbiology
@kaustuvsanyal.bsky.social
@viji-draviam.bsky.social
@spindlebehavior.bsky.social
Reposted by Sachin Kotak
The cover of @jcb.org's July issue (rupress.org/jcb/issue/22...) shows a confocal timelapse imaging of #Celegans one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein (Adhikary et al. doi.org/10.1083/jcb....)
July 7, 2025 at 2:04 PM
The cover of @jcb.org's July issue (rupress.org/jcb/issue/22...) shows a confocal timelapse imaging of #Celegans one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein (Adhikary et al. doi.org/10.1083/jcb....)